Tissue Ingrowth Markedly Reduces Mechanical Anisotropy and Stiffness in Fibre Direction of Highly Aligned Electrospun Polyurethane Scaffolds
ConclusionBased on the observations, it is proposed that the mechanism underlying the softening of the highly aligned scaffold in the predominant fibre direction is associated with scaffold compaction and local displacement of fibres by the newly formed tissue. The stiffening of the scaffold, observed transverse to highly aligned fibres and for more a random fibre distribution, represents the actual mechanical contribution of the tissue that developed in the scaffold. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - July 1, 2020 Category: Cardiology Source Type: research

Experimental Assessment of Two Non-Contrast MRI Sequences Used for Computational Fluid Dynamics: Investigation of Consistency Between Techniques
ConclusionIn conclusion, choosing different MRI sequences resulted in slightly different geometries of the same anatomy, which led to compounded errors in WSS quantities from CFD simulation. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - July 1, 2020 Category: Cardiology Source Type: research

Evaluation of the Effect of Crosslinking Method of Poly(Vinyl Alcohol) Hydrogels on Thrombogenicity
ConclusionThis work supports crosslinker dependent thrombogenicity of PVA hydrogels and advances our understanding of how the manufacturing of a PVA hydrogel affects its hemocompatibility. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 30, 2020 Category: Cardiology Source Type: research

Mitral Valve Posterior Leaflet Reconstruction Using Extracellular Matrix: In Vitro Evaluation
ConclusionsIn thisin vitro model, mitral valve anatomy and function were comparable between the native mitral valve and our new surgical technique for complete reconstruction of the posterior mitral leaflet and associated chordae tendineae. These promising results warrant furtherin vivo evaluation. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 26, 2020 Category: Cardiology Source Type: research

Haemodynamic Effect of Left Atrial and Left Ventricular Cannulation with a Rapid Speed Modulated Rotary Blood Pump During Rest and Exercise: Investigation in a Numerical Cardiorespiratory Model
ConclusionFor a simulated heart failure patient intending to complete exercise, LVC seems to assure a better hemodynamic performance in terms of pressure-volume area unloading and increasing RBP flow. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 16, 2020 Category: Cardiology Source Type: research

Influence of the Adopted Balloon Modeling Strategies in the Stent Deployment Procedure: An In-Silico Analysis
ConclusionThe hyperelastic taper-ended balloon suggests being the model that better correlates with both experimental and clinical results regarding the expanded balloon profile during the procedure. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 15, 2020 Category: Cardiology Source Type: research

Residual Stress Estimates from Multi-cut Opening Angles of the Left Ventricle
ConclusionWe conclude that both radial and circumferential cuts are required to release the residual stress in the left ventricle; using multiple radial cuts alone is not sufficient. A multiple-cut model gives a marked increase of residual stress in a left ventricle ring compared to that of the commonly used single-cut model. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 15, 2020 Category: Cardiology Source Type: research

Biomechanical Assessment of Bicuspid Aortic Valve Phenotypes: A Fluid –Structure Interaction Modelling Approach
ConclusionThe findings of this proof-of-concept work suggest that there are specific differences across haemodynamics and valve mechanics associated with BAV phenotypes, which may be critical to subsequent processes associated with their pathophysiology processes. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 9, 2020 Category: Cardiology Source Type: research

Role of Occlusion Position in Coronary Artery Fistulas with Terminal Aneurysms: A Hemodynamic Perspective
ConclusionsA proximal occlusion, namely, removing the aneurysm of the CAF, may help in reducing the risk of thrombosis after surgery. However, follow-up studies with a larger cohort should be carried out to test and verify this speculation in the future. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 1, 2020 Category: Cardiology Source Type: research

An Insight to the Role of Thermal Effects on the Onset of Atrioesophageal Fistula: A Computer Model of Open-Irrigated Radiofrequency Ablation
AbstractPurposeAtrial fibrillation (AF) is the most common heart rhythm disorder in the world. Radiofrequency catheter ablation (RFCA) has become the preferred method of treatment for drug-refractory AF. One of the rare (
Source: Cardiovascular Engineering and Technology - May 14, 2020 Category: Cardiology Source Type: research

Effect of the Center Post Establishment and Its Design Variations on the Performance of a Centrifugal Rotary Blood Pump
ConclusionsThe center post can greatly reduce the stagnation zone occurring in the center post free pump. The diameter of center post makes a difference to the flow field in the gap between the impeller and the center post. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - May 14, 2020 Category: Cardiology Source Type: research

Long-Term Venovenous Connection for Extracorporeal Carbon Dioxide Removal (ECCO 2 R) –Numerical Investigation of the Connection to the Common Iliac Veins
ConclusionIn conclusion, a connection without recirculation could be feasible and therefore provides a promising option for a long-term ECCO2R connection. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - May 13, 2020 Category: Cardiology Source Type: research

The Ryanodine Receptor Contributes to the Lysophosphatidylcholine-Induced Mineralization in Valvular Interstitial Cells
ConclusionsOur findings suggest blocking the activity of the ryanodine receptor can attenuate the valvular mineralization caused by LPC. We conclude that oxidized lipids, such as LPC, play an important role in the development and progression of CAVD and that the ryanodine receptor is a promising target for pharmacological intervention. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - April 30, 2020 Category: Cardiology Source Type: research

Non-Invasive Quantification of Ventricular Contractility, Arterial Elastic Function and Ventriculo-Arterial Coupling from a Single Diagnostic Encounter Using Simultaneous Arterial Tonometry and Magnetic Resonance Imaging
ConclusionNon-invasive assessment of LV pressure –volume and aortic pressure-flow relationships are both feasible and reproducible using simultaneous AT and CMRI. Methods permit assessment of load independent LV contractility, arterial function and LV/arterial coupling from a single non-invasive diagnostic encounter. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - April 20, 2020 Category: Cardiology Source Type: research

Large-Eddy Simulations of Flow in the FDA Benchmark Nozzle Geometry to Predict Hemolysis
ConclusionThe ICTVSS framework of generalizing laminar power-law models to turbulent flows shows promise, but would benefit from further numerical validation and carefully designed experiments. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - April 15, 2020 Category: Cardiology Source Type: research

Transcatheter Mitral Valve Replacement: State of the Art
AbstractThe emergence of transcatheter aortic valve replacement (TAVR) has segued the development of transcatheter mitral valve (MV) repair devices. Transcatheter mitral valve repair has become a well-established alternative for patients with severe primary and secondary mitral regurgitation (MR) and with a perceived surgical risk. Transcatheter mitral valve replacement (TMVR) could become a more complete form of reduction of severe MR compared to MV repair devices, albeit with significant engineering challenges and all the risks associated with a bioprosthetic heart valve. The development of TMVR devices has become promin...
Source: Cardiovascular Engineering and Technology - March 4, 2020 Category: Cardiology Source Type: research

Hemodynamic Effects of Additional Pulmonary Blood Flow on Glenn and Fontan Circulation
ConclusionsModerate APBF is not only a measure to promote pulmonary artery growth and systemic arterial oxygen saturation but also an effective method against endothelial dysfunction and thrombosis. However, moderate APBF is patient-specific and should be determined based on hemodynamic preference that leads to desired patient outcomes, and care should be taken to preventPRSVC and heart load from being too high as well as an imbalance in HFD. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - February 18, 2020 Category: Cardiology Source Type: research

Respiration and Heat Shock Protein After Short-Term Heating/Stretch-Fixing on Smooth Muscle Cells
ConclusionsSMCs heated at 60  °C with stretching would have high recovery ability and low respiratory activity related to SMC migration. These results may be important evidence in determining the treatment condition in PTDBA. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - February 3, 2020 Category: Cardiology Source Type: research

Post-exercise Response of Arterial Parameters for Arterial Health Assessment Using a Microfluidic Tactile Sensor and Vibration-Model-Based Analysis: A Proof-of-Concept Study
The objective of this study is to propose a novel method that can measure post-exercise response of arterial parameters and is also suitable for routine use.ApproachA microfluidic tactile sensor with a location-insensitive configuration was used for arterial pulse signal measurements on six asymptomatic male subjects, offering measurement reliability, ease use by a layperson, and affordability. By treating the arterial pulse signal as a vibration signal of the arterial wall, vibration-model-based analysis of only one measured pulse signal with no calibration was conducted for simultaneous estimation of three arterial param...
Source: Cardiovascular Engineering and Technology - January 30, 2020 Category: Cardiology Source Type: research

A Metabolic Intravascular Platform to Study FDG Uptake in Vascular Injury
ConclusionIn this study, we validated a tunable very sensitive metabolic sensor platform that can be used for the detection of vascular metabolism, such as inflammation. This sensor can be used not only for the detection of macrophage activity but, with alternative probes, it could allow the detection of other pathophysiological processes. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 30, 2020 Category: Cardiology Source Type: research

Speckle-Tracking Echocardiography Enables Model-Based Identification of Regional Stiffness Indices in the Left Ventricular Myocardium
ConclusionOur findings suggest that STE-integrated computational modeling can be used to track indices of LV myocardial stiffness and, thus, is a potential tool for HF diagnosis and prognosis. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 29, 2020 Category: Cardiology Source Type: research

Correlation Between Doppler Derived Carotid Artery Corrected Flow Time and Pressure Transducer Derived Radial Artery Corrected Flow Time: A Prospective Observational Study
AbstractPurposeCarotid artery corrected flow time (cFT) derived from Doppler USG is a known predictor of volume responsiveness. However, it can ’t be obtained continuously, and is operator dependent. In this prospective study, correlation between Doppler derived carotid artery cFT and pressure transducer derived radial artery cFT was evaluated in adult patients undergoing surgery under general anaesthesia.MethodsDoppler derived carotid artery cFT were obtained fromn = 51 adult patients atn = 125 time points. Simultaneously, pressure transducer waveforms were saved at the time of measuremen...
Source: Cardiovascular Engineering and Technology - January 16, 2020 Category: Cardiology Source Type: research

A Highly Conductive 3D Cardiac Patch Fabricated Using Cardiac Myocytes Reprogrammed from Human Adipogenic Mesenchymal Stem Cells
ConclusionBased on the results of this study, there is evidence to support the successful fabrication of a highly functional 3D patches with measurable electrical activity using cardiac myocytes reprogrammed from hADMSCs. 3D patches fabricated using optimal conductions described in this study can be used to improve the functional properties of failing hearts. Predominantly, in case of the infarcted hearts with partial loss of electrical activity, the electrical properties of the 3D patches may restore the electrical activity of the heart. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 8, 2020 Category: Cardiology Source Type: research

Inhibition of miR-217 Protects Against Myocardial Ischemia –Reperfusion Injury Through Inactivating NF-κB and MAPK Pathways
ConclusionsMiR-217 inhibition protected against MIRI through inactivating NF- κB and MAPK pathways by targeting DUSP14. This study may provide valuable diagnostic and factors and therapeutic agents for MIRI. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 8, 2020 Category: Cardiology Source Type: research

Effect of Aortic Wall Deformation with Healthy and Calcified Annulus on Hemodynamic Performance of Implanted On-X Valve
ConclusionsIn this study, the complex flow field characteristics in the new generation of BMHVs considering aorta flexibility with healthy and calcified annulus were investigated. It was found that the blood flow around the hinges region is in the danger of hemolysis and platelet activation and subsequently thromboembolism. Furthermore, the results show that similar to vessel wall deformation, considering the probable annulus calcification after valve replacement is also essential. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 7, 2020 Category: Cardiology Source Type: research

Influence of Configuration on Stress Distribution of Pulmonary Monocusp Leaflet
ConclusionsThe leaflet of model (1.2_min) had the most even stress distribution and lowest peak principal stress, which was the optimal choice among all the models. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 18, 2019 Category: Cardiology Source Type: research

Numerical Simulation of Magnetic Drug Targeting to the Stenosis Vessel Using Fe 3 O 4 Magnetic Nanoparticles Under the Effect of Magnetic Field of Wire
AbstractPurposeIn the present paper, the magnetic drug targeting using drug coated Fe3O4 nanoparticles to the stenosis region of the vessel was investigated. The problem was solved for various magnetic numbers. Moreover, the effect of the location of the wire, as a magnetic source, on the MDT was studied.MethodsThe governing equations of continuity, momentum and volume fraction were solved by taking into account the effects of kelvin force and magnetophoresis. Finite volume method is used for discretization of unsteady two-phase flow equations.ResultsIn low magnetic numbers, the most important phenomenon is the gradual for...
Source: Cardiovascular Engineering and Technology - December 18, 2019 Category: Cardiology Source Type: research

Future Balloon-Expandable Stents: High or Low-Strength Materials?
ConclusionUsing high-strength materials has a double-edged sword effect on the stent performance and existing uncertainty in the precise estimate of stent mechanical properties adversely affects the reliability of numerical models ’ predictions. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 13, 2019 Category: Cardiology Source Type: research

A Systematic Review for the Design of In Vitro Flow Studies of the Carotid Artery Bifurcation
ConclusionsA simplified three-step design process is proposed for better fitting and adequate match with the pertinent research question at hand and as guidance for less experienced flow study researchers. The three consecutive selection steps are: flow parameters, image modality, and model materials and designs. Model materials depend on the chosen imaging technique, whereas choice of flow parameters is independent from imaging technique and is therefore only determined by the goal of the study. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 10, 2019 Category: Cardiology Source Type: research

Hemodynamic Effects of Multiple Overlapping Uncovered Stents on Aortic Dissection: Surgical Strategies and Implications for False Lumen Thrombosis
ConclusionsMOUS helps to generate a favored hemodynamic environment for thrombus formation in the false lumen. Application of MOUS along with covered stent grafts may represent a more effective treatment for AD than utilizing MOUS or stent graft alone. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 9, 2019 Category: Cardiology Source Type: research

Evaluation of a Desktop 3D Printed Rigid Refractive-Indexed-Matched Flow Phantom for PIV Measurements on Cerebral Aneurysms
ConclusionsThis study presents an alternative low-cost option for 3D printing of a flow phantom suitable  for flow visualization simulations. The use of 3D printed flow phantoms reduces the complexity, time and effort required compared to conventional investment casting methods by removing the necessity of a multi-part process required with investment casting techniques. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 9, 2019 Category: Cardiology Source Type: research

The Implementation of an Adjustable Afterload Module for Ex Situ Heart Perfusion
ConclusionsWe conclude that due to the demonstrable control of our afterload module, we can maintain physiological aortic pressures in a passive afterload working mode across prolonged perfusion periods, enabling effective perfusion regardless of contractile performance. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 3, 2019 Category: Cardiology Source Type: research

Hydrodynamic Resistance of Intracranial Flow-Diverter Stents: Measurement Description and Data Evaluation
AbstractPurposeIntracranial aneurysms are malformations forming bulges on the walls of brain arteries. A flow diverter device is a fine braided wire structure used for the endovascular treatment of brain aneurysms. This work presents a rig and a protocol for the measurement of the hydrodynamic resistance of flow diverter stents. Hydrodynamic resistance is interpreted here as the pressure loss versus volumetric flow rate function through the mesh structure. The difficulty of the measurement is the very low flow rate range and the extreme sensitivity to contamination and disturbances.MethodsRigorous attention was paid to rep...
Source: Cardiovascular Engineering and Technology - December 3, 2019 Category: Cardiology Source Type: research

Cardiac Output Monitoring in Children, Adolescents and Adults Based on Pulse Contour Analysis: Comparison with Echocardiography-Derived Data and Identification of Factors Associated with Their Differences
ConclusionCO(PCA) had systematic (
Source: Cardiovascular Engineering and Technology - November 27, 2019 Category: Cardiology Source Type: research

Balloon Aortic Valvuloplasty Using a Non-Occlusive Balloon Catheter: First Animal Experience
ConclusionsThe novel non-occlusive balloon catheter, which permitted uninterrupted cardiac output for a prolonged period without the need for pacing-induced temporary cessation of cardiac output, is both feasible and well tolerated in the acute sheep model. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 18, 2019 Category: Cardiology Source Type: research

Effects of Normal Variation in the Rotational Position of the Aortic Root on Hemodynamics and Tissue Biomechanics of the Thoracic Aorta
ConclusionA clockwise rotational position of the aortic root imparts an increased wall shear stress at the sinutubular junction and proximal ascending aorta in comparison to other root rotation positions. This may pose increased risk for dilation of the sinutubular junction and ascending aorta in the patient with a clockwise positioned aortic root compared to other normal positional configurations. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 7, 2019 Category: Cardiology Source Type: research

A New Approach Based on a Multiobjective Evolutionary Algorithm for Accurate Control of Flow Rate and Blood Pressure in Cardiac Bioreactors
ConclusionThe strong non-linear interaction that exists between the three controlled variables makes it difficult to obtain a precise control of any of these, let alone all three simultaneously. However, the results showed that this new control algorithm can efficiently overcome such difficulties. In the particular field of bioreactors reproducing the cardiovascular environment, such a flexible, versatile and accurate reproduction of these three interdependent controlled variables is unprecedented. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 30, 2019 Category: Cardiology Source Type: research

Experimental and Numerical Simulation of Biodegradable Stents with Different Strut Geometries
ConclusionAnalysis of the stent parameters indicates that the hexagonal geometry is a relatively good stent strut design. The results described in this paper will be useful in further optimization studies and for the development of stents with a higher radial strength and increased fracture resistance. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 29, 2019 Category: Cardiology Source Type: research

Non-physiologic Bioreactor Processing Conditions for Heart Valve Tissue Engineering
ConclusionThese results suggest the use of non-physiologic bioreactor conditioning parameters can increasein vitro recellularization of tissue engineered heart valve leaflets. Particularly, hypoxic culture was found to increase the cellular infiltration. Therefore, bioreactor conditioning of tissue engineered constructs need not always mimic physiologic conditions, and it is worth investigating novel or uncharacteristic culture conditions as they may benefit aspects of tissue culture. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 24, 2019 Category: Cardiology Source Type: research

Cardiothoracic Morphology Measures in Heart Failure Patients to Inform Device Designs
ConclusionsThese cardiothoracic morphology measurements are important to consider in the design of cardiac devices for heart failure management (e.g. cardiac pacemakers, ventricular assist devices, and implantable defibrillators), since morphology differs by sex and ejection fraction. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 21, 2019 Category: Cardiology Source Type: research

Cilostazol Promotes Angiogenesis and Increases Cell Proliferation After Myocardial Ischemia –Reperfusion Injury Through a cAMP-Dependent Mechanism
ConclusionCilostazol could promote angiogenesis, increase cell viability and inhibit cell apoptosis, consequently protecting myocardial tissues against I/R-injury through activating cAMP. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 17, 2019 Category: Cardiology Source Type: research

Three-Dimensional Contractile Mechanics of Artery Accounting for Curl of Axial Strip Sectioned from Vessel Wall
ConclusionsWe have shown that the Riemannian stress-free configuration is appropriate tool to analyze stress distributions of arterial wall under passive and activated conditions with the residual stresses. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 17, 2019 Category: Cardiology Source Type: research

Haemodynamics Study of Tapered Stents Intervention to Tapered Arteries
ConclusionsThe implantation of a tapered stent in the tapered artery can effectively improve intravascular haemodynamics. The tapered stent allows the tapered artery to obtain better haemodynamics and reduces the probability of ISR. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 15, 2019 Category: Cardiology Source Type: research

Vascular Parameters for Ambulatory Monitoring of Congestive Heart Failure Patients: Proof of Concept
ConclusionHome monitoring of some of the proposed parameters could detect HF deterioration on its onset and alert to health personnel. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 9, 2019 Category: Cardiology Source Type: research

Automated Detection of Vulnerable Plaque for Intravascular Optical Coherence Tomography Images
ConclusionsThe proposed algorithms can detect vulnerable plaques with superior performance; our system can be used as an auxiliary diagnostic tool for vulnerable plaque detection in IVOCT images. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - September 18, 2019 Category: Cardiology Source Type: research

Location-Specific Comparison Between a 3D In-Stent Restenosis Model and Micro-CT and Histology Data from Porcine In Vivo Experiments
ConclusionsThe approach presented here provides a very detailed, location-specific, validation methodology forin silico restenosis models. The model was able to closely match both histology datasets with a single set of parameters. Good agreement was obtained for both the overall amount of neointima produced and the local distribution. It should be noted that including vessel curvature and ECM production in the model was paramount to obtain a good agreement with the experimental data. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - September 17, 2019 Category: Cardiology Source Type: research

Optimization Framework for Patient-Specific Cardiac Modeling
ConclusionsThis work will facilitate the use of biomechanics and circulatory cardiac models in both clinical and research environments by ameliorating the tedious process of manually fitting the parameters. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - September 17, 2019 Category: Cardiology Source Type: research

Embolus Transport Simulations with Fully Resolved Particle Surfaces
AbstractPurposeThere has been interest in recent work in using computational fluid dynamics with Lagrangian analysis to calculate the trajectory of emboli-like particles in the vasculature. While previous studies have provided an understanding of the hemodynamic factors determining the fates of such particles and their relationship to risk of stroke, most analyses have relied on a particle equation of motion that assumes the particle is “small” e.g., much less than the diameter of the vessel. This work quantifies the limit when a particle can no longer be considered “small”.MethodsThe motion of embo...
Source: Cardiovascular Engineering and Technology - September 16, 2019 Category: Cardiology Source Type: research

Editorial
(Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - August 20, 2019 Category: Cardiology Source Type: research

Design and Computational Validation of a Novel Bioreactor for Conditioning Vascular Tissue to Time-Varying Multidirectional Fluid Shear Stress
ConclusionsA bioreactor capable of generating simultaneously desired time-varying WSS magnitude and directionality was designed and validated computationally. The ability to subject tissue toin vivo-like WSS will provide new insights into cardiovascular mechanobiology and disease. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - July 15, 2019 Category: Cardiology Source Type: research