Case report: Antiphospholipid syndrome presenting as primary adrenal insufficiency
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - February 7, 2024 Category: Rheumatology Authors: Akhil Pawan Goel, Atul Dhingra Tags: LETTER TO THE EDITOR Source Type: research

The impact of hormones in autoimmune cutaneous diseases
CONCLUSION: Pregnancy, menopause, contraceptive use, hormone replacement therapy, and breast cancer treatment drugs result in substantial shifts in hormone levels. Additionally, hormone levels are altered by aromatase inhibitors and anti-estrogen medications. These fluctuations can modulate mechanisms influencing autoimmune skin abnormalities.PMID:38317519 | DOI:10.1080/09546634.2024.2312241 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 6, 2024 Category: Dermatology Authors: Lais Lopes Almeida Gomes Adrienne J Werth Preethi Thomas Victoria P Werth Source Type: research

Taipan snake venom time has high sensitivity for lupus anticoagulants in non-anticoagulated, triple positive antiphospholipid syndrome patients
CONCLUSIONS: TSVT/ET has high sensitivity for the clinically significant LA found in triple positive APS patients. TSVT/ET can establish multiple LA assay positivity in nonanticoagulated patients negative for one of dRVVT or APTT, and is the only assay pairing insensitive to VKAs, the recommended anticoagulation for APS.PMID:38303489 | DOI:10.1111/ijlh.14240 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - February 2, 2024 Category: Hematology Authors: Gary W Moore Sean Platton Nada Yartey Eleanor Foxton Danielle White Stephen G MacDonald Source Type: research

Spontaneous intracranial hypotension and bilateral subdural hematoma in the spectrum of antiphospholipid syndrome and systemic lupus erythematosus: a challenging clinical encounter
Future Neurology, Ahead of Print. (Source: Future Neurology)
Source: Future Neurology - February 2, 2024 Category: Neurology Authors: Arsh Haj Mohamad Ebrahim Ketabforoush Zahra Ahmadian Armin Ariaei Ali Hosseinpour Nahid Abbasi Khoshsirat Source Type: research

Coil Embolization of a Large Recurrent Pulmonary Arteriovenous Malformation by Retrograde Transseptal Pulmonary Vein Access
A 55-year-old woman presented with stroke and exercise intolerance and was found to have a complex right lower lobe pulmonary arteriovenous malformation (PAVM). The PAVM morphology was complex with an extensive number of small feeding arteries/arterioles and 1 dominant draining vein (Fig 1). The PAVM was treated with transarterial embolization in 3 separate procedures over a 6-year time span, using multiple vascular plugs and coils. The patient was also diagnosed with antiphospholipid syndrome and started on warfarin anticoagulation. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - February 2, 2024 Category: Radiology Authors: Peter Barrale, Osamah Aldoss, Prashob Porayette, Bassel Mohammad Nijres, Mohammad A. Amarneh Tags: Letter to the Editor Source Type: research

Antiphospholipid Antibodies (aPL) and Thrombotic Microangiopathy for the Diagnosis of aPL Nephropathy: You Can't Have One Without the Other
J Rheumatol. 2024 Feb 1;51(2):109-111. doi: 10.3899/jrheum.2023-1096.NO ABSTRACTPMID:38302187 | DOI:10.3899/jrheum.2023-1096 (Source: J Rheumatol)
Source: J Rheumatol - February 1, 2024 Category: Rheumatology Authors: Charles E Alpers Source Type: research

Antiphospholipid Antibodies (aPL) and Thrombotic Microangiopathy for the Diagnosis of aPL Nephropathy: You Can't Have One Without the Other
J Rheumatol. 2024 Feb 1;51(2):109-111. doi: 10.3899/jrheum.2023-1096.NO ABSTRACTPMID:38302187 | DOI:10.3899/jrheum.2023-1096 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 1, 2024 Category: Rheumatology Authors: Charles E Alpers Source Type: research

Pitfalls in antiphospholipid antibody testing: specifically interference from anticoagulation
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - February 1, 2024 Category: Rheumatology Source Type: research

Lipid-binding antiphospholipid antibodies: significance for pathophysiology and diagnosis of the antiphospholipid syndrome
. (Source: Critical Reviews in Clinical Laboratory Sciences)
Source: Critical Reviews in Clinical Laboratory Sciences - January 31, 2024 Category: Laboratory Medicine Authors: Nadine M üller-CallejaWolfram RufKarl J. Lacknera Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University, Mainz, Germanyb Center for Thrombosis and Hemostasis (CTH), University Medical Cent Source Type: research

An immunogenomic exome landscape of triple positive primary antiphospholipid patients
Genes & Immunity, Published online: 24 January 2024; doi:10.1038/s41435-024-00255-wAn immunogenomic exome landscape of triple positive primary antiphospholipid patients (Source: Genes and Immunity)
Source: Genes and Immunity - January 24, 2024 Category: Genetics & Stem Cells Authors: A. Guffroy L. Jacquel Y. Seeleuthner N. Paul V. Poindron F. Maurier V. Delannoy A. C. Voegeli P. Zhang B. Nespola A. Molitor M. J. Apithy P. Soulas-Sprauel T. Martin R. E. Voll S. Bahram V. Gies J. L. Casanova A. Cobat B. Boisson R. Carapito A. S. Korgano Source Type: research

Analysis of clinical, immunological characteristics, damage, and survival in 300 Turkish systemic lupus erythematosus patients
CONCLUSION: Ethnicity and geography influence the clinical diversity of SLE. Recognizing these disparities is crucial for tailoring patient care. Future inception cohort studies in Turkish SLE patients are necessary to address the limitations of retrospective research.PMID:38258530 | DOI:10.1177/09612033241228174 (Source: Lupus)
Source: Lupus - January 23, 2024 Category: Rheumatology Authors: Senem Tekeoglu Duygu Temiz Karadag Ozlem Ozdemir Isik Ayten Yazici Ayse Cefle Source Type: research

The prevalence and incidence of thrombotic primary antiphospholipid syndrome in adults aged 18-49  years: A population-based study in a mountain community in northern Italy
CONCLUSIONS: Thrombotic PAPS was found to be a rare disease in this population-based study. Prevalence and incidence were not significantly different between males and females aged 18-49 years, but a different type of onset was observed.PMID:38246213 | DOI:10.1016/j.clim.2024.109905 (Source: Clinical Immunology)
Source: Clinical Immunology - January 21, 2024 Category: Allergy & Immunology Authors: Laura Andreoli Cecilia Nalli Elena Raffetti Fabrizio Angeli Greta Pascariello Arianna Zentilin Federica Pedersoli Cinzia Gasparotti Michele Magoni Carmelo Scarcella Giuliana Martini Franco Franceschini Francesco Donato Angela Tincani Source Type: research

The effects of hydroxychloroquine and its promising use in refractory obstetric antiphospholipid syndrome
AbstractHydroxychloroquine (HCQ) is obtained by hydroxylation of chloroquine (CQ) and the first indication was malaria. Nowadays, HCQ is commonly used in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) with favorable results. Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombosis and/or pregnancy morbidity and persistent positivity of antiphospholipid antibodies. Around 20 –30% of pregnant women with APS develop adverse pregnancy outcomes despite conventional treatment with aspirin and heparin, called refractory obstetric APS. Interestingly, HCQ has shown positive effects on...
Source: Rheumatology International - January 20, 2024 Category: Rheumatology Source Type: research