The obstetrical consequences of ischemic stroke in women of childbearing age
CONCLUSIONS: We observed no recurrence of IS during pregnancy. The study also highlighted that the risk of miscarriages was higher than general population and that of stillbirth should be further studied.PMID:38679658 | DOI:10.1007/s00404-024-07498-y (Source: Atherosclerosis)
Source: Atherosclerosis - April 28, 2024 Category: Cardiology Authors: Jeremy David Helene Desmurs-Clavel Laura Mechtouff Anne Long Yesim Dargaud Judith Catella Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

Renal artery occlusion in a young woman - a tale of mysterious thrombosis
CONCLUSION: Renal artery thrombosis in young people is extremely rare and presents a diagnostic and management challenge requiring input from multiple teams including nephrology, rheumatology, paediatrics and vascular surgery. Systemic coagulopathy and vasculitis are differentials against anatomical aetiologies such as fibromuscular dysplasia. Our case adds to the limited literature regarding this in the young population. Renal artery thrombosis with occlusion in young people is very rare and is most often associated with a systemic coagulopathic disorder, such as antiphospholipid syndrome or structural pathology of the re...
Source: Vascular - April 26, 2024 Category: Surgery Authors: Ned Farley Joseph Faraj Malindu Fernando Tejas Singh Aaron Powell Senthil Kumar Source Type: research

The clinical relevance of different antiphospholipid antibody profiles in pediatric rheumatology patients
The clinical relevance of different antiphospholipid antibody (aPL) profiles, including low level anticardiolipin (aCL) and anti- β2-glycoprotein-I (aβ2GPI) antibodies, is ill-defined in the pediatric population. ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 26, 2024 Category: Rheumatology Authors: Jheel Pandya, Karen Onel and Doruk Erkan Tags: Short Report Source Type: research

Long-term incidence, risk factors and complications for venous thromboembolism in patients with systemic lupus erythematosus
CONCLUSIONS: VTE affected 12.8% of patients with SLE at six times the VTE rate in controls with aPL as the strongest, but not the only risk factor in SLE. The risk of PH was increased in both groups following PE, but VTE did not associate with an increased risk of arterial events.PMID:38655753 | DOI:10.1177/09612033241247359 (Source: Lupus)
Source: Lupus - April 24, 2024 Category: Rheumatology Authors: Johannes Cornelis Nossent Helen Isobel Keen David Brian Preen Charles Anoukpar Inderjeeth Source Type: research

Eculizumab administration for myasthenia gravis also stabilizes thrombogenicity of catastrophic antiphospholipid syndrome
ConclusionsEculizumab can be effective for controlling multiple complement-mediated pathophysiology. (Source: Clinical and Experimental Neuroimmunology)
Source: Clinical and Experimental Neuroimmunology - April 23, 2024 Category: Neurology Authors: Sunao Takahashi, Nobuo Sanjo, Ryuji Koike, Takanori Yokota Tags: CASE REPORT Source Type: research

Antiphospholipid Patients Admitted in the Intensive Care Unit: What Must The Rheumatologist Know?
AbstractPurpose of the reviewAntiphospholipid syndrome (APS) is a rare systemic autoimmune disorder that can escalate into a 'thrombotic storm' called the catastrophic antiphospholipid syndrome (CAPS), frequently requiring ICU admission for multiple organ failure. This review aims to offer insight and recent evidence on critically-ill APS patients.Recent findingsThe CAPS classification criteria define this condition as the involvement of at least three organs/systems/tissues within less than a week, caused by small vessel thrombosis, in patients with elevated antiphospholipid antibodies levels. These criteria do not encomp...
Source: Current Rheumatology Reports - April 23, 2024 Category: Rheumatology Source Type: research

T cell involvement in antiphospholipid syndrome
Clin Immunol. 2024 Apr 17:110218. doi: 10.1016/j.clim.2024.110218. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by arterial and venous thrombosis, and obstetric complications in the presence of antiphospholipid antibodies (aPL), including lupus anticoagulant, anticardiolipin and anti-β2-glycoprotein I antibodies, manifesting as single, or often as recurrent events, and rarely as a catastrophic condition. Most studies of APS pathogenesis to date have focused on the prothrombotic role of aPL, while innate immune components such as monocyte, complement and neut...
Source: Clinical Immunology - April 19, 2024 Category: Allergy & Immunology Authors: Maria G Tektonidou Nikolaos I Vlachogiannis Petros P Sfikakis Source Type: research

Waldmann's disease: Primary intestinal lymphangiectasia diagnosed by 99mTc ‐labeled albumin macroaggregate scintigraphy—A case report in an adult patient
Key Clinical MessageRare yet significant, this case sheds light on the uncommon presentation of Waldmann's disease in adults, showcasing the diagnostic challenges it poses. A multidisciplinary approach, integrating clinical, endoscopic, histological, and radiological evaluations, is crucial for accurate diagnosis and management. Further research is needed to deepen our understanding of this complex disorder.AbstractWaldmann's disease, or primary intestinal lymphangiectasia, is a rare disorder characterized by protein-losing enteropathy due to dilation and leakage of intestinal lymphatic vessels. Although typically diagnose...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Alex Jos é Castellón Méndez, Allan Bodán Campbell, Victor Rosales Obregón, Mohammed Zahran Tags: CASE REPORT Source Type: research