Proceedings from the 2nd Next Gen Therapies for Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome symposium held on October 3-4, 2019
For reasons poorly understood, and despite the availability of biological medications blocking IL-1 and IL-6 that have markedly improved overall disease control, children with Systemic Juvenile Idiopathic Arth... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 15, 2020 Category: Rheumatology Authors: Scott W. Canna, Grant S. Schulert, Adriana de Jesus, Alex Pickering, Hermine Brunner, Massimo Gadina, Stewart Levine, Raphaela Goldbach-Mansky, Jonathan Boutelle, Rashmi Sinha, Fabrizio DeBenedetti and Alexei Grom Tags: Meeting report Source Type: research

Subclinical cardiovascular risk signs in adults with juvenile idiopathic arthritis in sustained remission
Juvenile Idiopathic Arthritis (JIA) is one of the most common chronic diseases of childhood that often persists into adulthood and can result in significant long-term morbidity. As a long lasting chronic infla... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 14, 2020 Category: Rheumatology Authors: Inmaculada Concepci ón Aranda-Valera, Iván Arias de la Rosa, Rosa Roldán-Molina, María del Carmen Ábalos-Aguilera, Carmen Torres-Granados, Alejandra Patiño-Trives, María Luque-Tevar, Alejandro Ibáñez-Costa, Rocío Guzmán-Ruiz, María del Mar Mal Tags: Research article Source Type: research

The paediatric global musculoskeletal task force - ‘towards better MSK health for all’
There is increasing concern about the emerging global non-communicable diseases (NCDs) burden. The focus has mainly been on NCDs in adults but it is important that MSK morbidity in both children and adults is ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 14, 2020 Category: Rheumatology Authors: Helen E. Foster, Christiaan Scott, Carl J. Tiderius and Matthew B. Dobbs Tags: Commentary Source Type: research

Neurological involvement in Kawasaki disease: a retrospective study
Kawasaki disease (KD) is an acute, self-limiting systemic vasculitis that predominately affects children. Neurological involvement is a known complication of KD, however, its association with KD severity remai... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 14, 2020 Category: Rheumatology Authors: Xiaoliang Liu, Kaiyu Zhou, Yimin Hua, Mei Wu, Lei Liu, Shuran Shao and Chuan Wang Tags: Research article Source Type: research

Assessment and treatment of Down syndrome-associated arthritis: a survey of pediatric rheumatologists
Inflammatory arthritis in children with Down syndrome (DS) was first described in 1984 and is now termed Down syndrome-associated arthritis (DA). Studies have shown that DA is under-recognized with a 19-month ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 13, 2020 Category: Rheumatology Authors: Anna Nicek, Nasreen Talib, Daniel Lovell, Chelsey Smith, Mara L. Becker and Jordan T. Jones Tags: Research article Source Type: research

Leukoencephalopathy and cerebral edema as the presenting manifestations of SLE in an ANA-negative adolescent female: a case report and review of literature
Systemic lupus erythematosus (SLE) is an autoimmune disease with various clinical manifestations involving multiple organ systems. Neuropsychiatric manifestations of SLE have been associated with increased mor... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 13, 2020 Category: Rheumatology Authors: Alexandra Theisen, Paroma Bose, Christina Knight and Melissa Oliver Tags: Case Report Source Type: research

Successful treatment of refractory hyperferritinemic syndromes with canakinumab: a report of two cases
Hyperferritinemic syndromes are systemic inflammatory disorders characterized by a dysfunctional immune response, which leads to excessive activation of the monocyte-macrophage system with hypercytokinemia and... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 11, 2020 Category: Rheumatology Authors: Riccardo Papa, Valentina Natoli, Roberta Caorsi, Francesca Minoia, Marco Gattorno and Angelo Ravelli Tags: Case Report Source Type: research

Adenosine deaminase 2 activity negatively correlates with age during childhood
Human adenosine deaminase 2 (ADA2) is an extracellular enzyme that negatively regulates adenosine-mediated cell signaling by converting adenosine to inosine. Altered ADA2 enzyme activity has been associated wi... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 10, 2020 Category: Rheumatology Authors: Sarah M. Bowers, Kristen M. Gibson, David A. Cabral and Kelly L. Brown Tags: Research article Source Type: research

High prevalence of rare FBLIM1 gene variants in an Italian cohort of patients with Chronic Non-bacterial Osteomyelitis (CNO)
FBLIM1 gene has been recently demonstrated to be involved in the pathogenesis of bone sterile inflammation. The aim of the study is to evaluate the prevalence of FBLIM1 gene variants in a cohort of 80 Italian pat... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 10, 2020 Category: Rheumatology Authors: Adamo Pio d ’Adamo, Anna Monica Bianco, Giovanna Ferrara, Martina La Bianca, Antonella Insalaco, Alberto Tommasini, Manuela Pardeo, Marco Cattalini, Francesco La Torre, Martina Finetti, Clotilde Alizzi, Gabriele Simonini, Virginia Messia, Serena Pastore Tags: Research article Source Type: research

Image guided sacroiliac joint corticosteroid injections in children: an 18-year single-center retrospective study
Sacroiliitis is commonly seen in enthesitis-related arthritis (ERA), a subtype of juvenile idiopathic arthritis (JIA). Sacroiliitis is characterized by the inflammation of the sacroiliac (SI) joints (+/ − adjac... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 17, 2020 Category: Rheumatology Authors: Racha Chamlati, Bairbre Connolly, Ronald Laxer, Jennifer Stimec, Jyoti Panwar, Shirley Tse, Prakash Muthusami, Joao Amaral, Michael Temple and Dimitri A. Parra Tags: Research article Source Type: research

Failure of anti Interleukin-1 β monoclonal antibody in the treatment of recurrent pericarditis in two children
Recurrent pericarditis (RP) is a complication (15 –30%) of acute pericarditis with an unknown etiology. Treatment regimen consists of a combination of non-steroidal anti-inflammatory drugs (NSAIDs) and colchici... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 16, 2020 Category: Rheumatology Authors: Sara Signa, Matteo D ’Alessandro, Rita Consolini, Angela Miniaci, Marta Bustaffa, Chiara Longo, Maria A. Tosca, Martina Bizzi, Roberta Caorsi, Leonardo Oliveira Mendonça, Andrea Pession, Angelo Ravelli and Marco Gattorno Tags: Case Report Source Type: research

Neonatal Kawasaki disease with multiple arterial aneurysms: a case report
Kawasaki disease (KD) is a medium vessel vasculitis that typically occurs in children aged between 6  months and 5 years. It is extraordinarily rare in the neonatal period. KD-related systemic artery aneurysms ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 15, 2020 Category: Rheumatology Authors: Qu-ming Zhao, Xue-cun Liang, Lin Wu and Fang Liu Tags: Case Report Source Type: research

Global prevalence estimates of three chronic musculoskeletal conditions: club foot, juvenile idiopathic arthritis and juvenile systemic lupus erythematosus
Musculoskeletal (MSK) conditions are a major source of morbidity and disability. There is a lack of global comparable data on the burden of MSK conditions in children and young people. Our aim was to estimate ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 12, 2020 Category: Rheumatology Authors: Mona Dave, Judith Rankin, Mark Pearce and Helen E. Foster Tags: Research article Source Type: research

Effect of different doses of aspirin on the prognosis of Kawasaki disease
Kawasaki disease (KD) is the leading cause of acquired heart disease in children, and is steadily increasing in prevalence in East Asia. KD is often complicated by coronary artery damage, including dilatation ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 11, 2020 Category: Rheumatology Authors: Jinxin Wang, Huiqiao Chen, Hongying Shi, Xuting Zhang, Yiping Shao, Biyao Hang, Zhipeng Xu, Xing Rong, Maoping Chu and Huixian Qiu Tags: Research article Source Type: research

Salivary gland ultrasound in the diagnostic workup of juvenile Sj ögren’s syndrome and mixed connective tissue disease
Juvenile Sj ögren’s Syndrome (jSS) is a rare phenomenon that may appear as primary jSS or associated with mixed connective tissue disease (MCTD) and other autoimmune diseases as secondary jSS. With currently no... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 9, 2020 Category: Rheumatology Authors: Manuela Krumrey-Langkammerer and Johannes-Peter Haas Tags: Research article Source Type: research

Vitamin C deficiency mimicking inflammatory bone disease of the hand
Severe vitamin C deficiency, or scurvy, encompasses a syndrome of multisystem abnormalities due to defective collagen synthesis and antioxidative functions. Among the more common presentations is a combination... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 9, 2020 Category: Rheumatology Authors: Emily J. Liebling, Raymond W. Sze and Edward M. Behrens Tags: Case Report Source Type: research

C-type natriuretic peptide stimulates osteoblastic proliferation and collagen-X expression but suppresses fibroblast growth factor-23 expression in vitro
The effects of C-type natriuretic peptide (CNP) and fibroblast growth factor (FGF)-23 appear to oppose each other during the process of bone formation, whereas few studies exist on the interaction between CNP ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 9, 2020 Category: Rheumatology Authors: Wei Xia Chen, Hui Hui Liu, Rui Xue Li, Goshgar Mammadov, Jing Jing Wang, Fei Fei Liu, Sama Samadli, Yang Fang Wu, Dong Dong Zhang, Huang Huang Luo and Peng Hu Tags: Research article Source Type: research

Artificial intelligence for interpretation of segments of whole body MRI in CNO: pilot study comparing radiologists versus machine learning algorithm
To initiate the development of a machine learning algorithm capable of comparing segments of pre and post pamidronate whole body MRI scans to assess treatment response and to compare the results of this algori... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 9, 2020 Category: Rheumatology Authors: Chandrika S. Bhat, Mark Chopra, Savvas Andronikou, Suvadip Paul, Zach Wener-Fligner, Anna Merkoulovitch, Izidora Holjar-Erlic, Flavia Menegotto, Ewan Simpson, David Grier and Athimalaipet V. Ramanan Tags: Research article Source Type: research

Prevalence of co-existing autoimmune disease in juvenile idiopathic arthritis: a cross-sectional study
Many autoimmune diseases share common pathogenic mechanisms, cytokine pathways and systemic inflammatory cascades; however, large studies quantifying the co-existence of autoimmune diseases in patients with ju... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 5, 2020 Category: Rheumatology Authors: Teresa A. Simon, Gowri Priya Harikrishnan, Hugh Kawabata, Sanket Singhal, Hermine I. Brunner and Daniel J. Lovell Tags: Research article Source Type: research

Usefulness of magnetic resonance enterography in detecting signs of sacroiliitis in young patients with inflammatory bowel disease
Arthritis is often an underestimated extraintestinal manifestation in pediatric inflammatory bowel disease (IBD), including sacroiliitis, whose early signs are well detectable at magnetic resonance imaging (MR... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 3, 2020 Category: Rheumatology Authors: Teresa Giani, Azzurra Bernardini, Massimo Basile, Marco Di Maurizo, Anna Perrone, Sara Renzo, Viola Filistrucchi, Rolando Cimaz and Paolo Lionetti Tags: Research article Source Type: research

Nephrological disorders and neurological involvement in pediatric primary Sjogren syndrome:a case report and review of literature
Sj ögren syndrome (SS) is a rare disease in pediatrics, and little attention has been paid to the clinical feature in these patients. To date, there are few cases concern about neurological and nephrological di... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - May 24, 2020 Category: Rheumatology Authors: Jingya Zhao, Qin Chen, Yunyun Zhu, Meng Zhao, Jun Liu, Zhenzhong Zhang and Xiaoting Gong Tags: Case Report Source Type: research

Recurrent Henoch-Sch önlein Purpura with bullous rash and pulmonary nodules
Henoch-Sch önlein purpura (HSP) is the most common vasculitis of childhood. It has a characteristic rash described as palpable purpura that most frequently affects the distal lower extremities and buttocks. HSP... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - May 24, 2020 Category: Rheumatology Authors: Christopher Zheng, Julie Childers, Egla Rabinovich and Kristina Nazareth-Pidgeon Tags: Case Report Source Type: research

Assessing the reporting quality of physical activity programs in randomized controlled trials for the management of juvenile idiopathic arthritis using three standardized assessment tools
This study aimed to assess and compare... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - May 24, 2020 Category: Rheumatology Authors: Teresa-Rose Kattackal, Sabrina Cavallo, Lucie Brosseau, Aditi Sivakumar, Michael J. Del Bel, Michelle Dorion, Erin Ueffing and Karine Toupin-April Tags: Research article Source Type: research

Type 1 interferonopathy presenting as juvenile idiopathic arthritis with interstitial lung disease: report of a new phenotype
STING-associated vasculopathy with onset in infancy (SAVI) is a type 1 interferonopathy manifesting as a pulmonary and vascular syndrome resulting from gain-of-function mutations in TMEM173, the gene encoding STI... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - May 12, 2020 Category: Rheumatology Authors: S. L. N. Clarke, L. Robertson, G. I. Rice, L. Seabra, T. N. Hilliard, Y. J. Crow and A. V. Ramanan Tags: Case Report Source Type: research

The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis
Systemic juvenile idiopathic arthritis (sJIA) has many clinical features overlapping with familial Mediterranean fever (FMF), which is caused by mutations in MEFV gene. And FMF patients were easily misdiagnosed a... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - May 12, 2020 Category: Rheumatology Authors: Linqing Zhong, Wei Wang, Ji Li, Mingsheng Ma, Lijuan Gou, Changyan Wang, Zhongxun Yu, Tiannan Zhang, Yanqing Dong, Qijiao Wei and Hongmei Song Tags: Research article Source Type: research

Feasibility and acceptability of an innovative adherence intervention for young adults with childhood-onset systemic Lupus Erythematosus
In Childhood-Onset Systemic Lupus Erythematosus (cSLE), poor medication adherence rates are very high. Interventions targeting this problem in cSLE are limited thus effective interventions are needed. The obje... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 26, 2020 Category: Rheumatology Authors: Onengiya Harry, Lori E. Crosby, Constance Mara, Tracy V. Ting, Jennifer L. Huggins and Avani C. Modi Tags: Research article Source Type: research

COVID-19 and what pediatric rheumatologists should know: a review from a highly affected country
On March 11th, 2020 the World Health Organization declared COVID-19 a global pandemic. The infection, transmitted by 2019 novel coronavirus (2019-nCov), was first discovered in December 2019, in Wuhan, Hubei P... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 22, 2020 Category: Rheumatology Authors: Francesco Licciardi, Teresa Giani, Letizia Baldini, Ennio Giulio Favalli, Roberto Caporali and Rolando Cimaz Tags: Review Source Type: research

Treating juvenile idiopathic arthritis to target: what is the optimal target definition to reach all goals?
In 2018, an international Task Force formulated recommendations for treating Juvenile Idiopathic Arthritis (JIA) to target. The Task Force has not yet resolved three issues. The first issue is the lack of a si... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 16, 2020 Category: Rheumatology Authors: Casper G. Schoemaker, Joost F. Swart and Nico M. Wulffraat Tags: Commentary Source Type: research

Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is the most common periodic fever syndrome in children. There is considerable heterogeneity in management strategies and... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 15, 2020 Category: Rheumatology Authors: Gil Amarilyo, Deborah Rothman, Kalpana Manthiram, Kathryn M. Edwards, Suzanne C. Li, Gary S. Marshall, Cagri Yildirim-Toruner, Kathleen Haines, Polly J. Ferguson, Geraldina Lionetti, Julie Cherian, Yongdong Zhao, Patricia DeLaMora, Grant Syverson, Simona Tags: Research article Source Type: research

Familial chilblain lupus due to a novel mutation in TREX1 associated with Aicardi –Goutie’res syndrome
Familial chilblain lupus (FCL) is a rare, chronic form of cutaneous lupus erythematosus, which is characterized by painful bluish-red inflammatory cutaneous lesions in acral locations. Mutations in TREX1, SAMHD1 ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 15, 2020 Category: Rheumatology Authors: Cuili Yi, Qiyuan Li and Jihong Xiao Tags: Case Report Source Type: research

Experiences, perspectives and expectations of adolescents with juvenile idiopathic arthritis regarding future work participation; a qualitative study
Having Juvenile idiopathic Arthritis (JIA) has widespread implications for a person ’s life. Patients have to deal with recurring arthritis, characterized by pain often accompanied by a loss of energy. Since JI... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 15, 2020 Category: Rheumatology Authors: E. Charlotte van Gulik, Floris Verkuil, Anouk M. Barendregt, Dieneke Schonenberg-Meinema, Amara Nassar-Sheikh Rashid, Taco W. Kuijpers, J. Merlijn van den Berg and Jan L. Hoving Tags: Research article Source Type: research

Choroidal vascularity index as a biomarker of systemic inflammation in childhood Polyarteritis Nodosa and adenosine deaminase-2 deficiency
To assess EDI-OCT (enhanced depth imaging optical coherence tomography) of choroid for inflammatory signs in children with polyarteritis nodosa (PAN) and adenosine deaminase-2 deficiency (DADA-2). (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 3, 2020 Category: Rheumatology Authors: Ata BAYTARO ĞLU, Sibel KADAYIFÇILAR, Abdullah AĞIN, Özge DELİKTAŞ, Selcan DEMİR, Yelda BİLGİNER, Jale KARAKAYA, Seza ÖZEN and Bora ELDEM Tags: Research article Source Type: research

Spectrum of paediatric rheumatic disorders at a tertiary hospital in Tanzania
Paediatric rheumatic disorders are common in children and result in significant impairment in quality of life, morbidity and mortality. There is limited information on the burden of these disorders in lower in... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 3, 2020 Category: Rheumatology Authors: Francis F. Furia, Evance Godfrey, Naomi Mwamanenge and Peter Swai Tags: Research article Source Type: research

A preliminary study of the child abuse and central sensitization in adolescent patients with chronic non-organic chest pain and an overlooked condition: juvenile fibromyalgia syndrome
Only a small percentage of pediatric chest pain is of cardiac origin and the most common detected cause is musculoskeletal. Among musculoskeletal causes, acute chest pain is better described, with the causes o... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 31, 2020 Category: Rheumatology Authors: Basak Mansiz-Kaplan, F. Figen Ayhan, Mihriban Cagli, Fatih Atik and İbrahim Ece Tags: Research article Source Type: research

Inpatient mortality in transition-aged youth with rheumatic disease: an analysis of the National Inpatient Sample
Transition from pediatric to adult care is a vulnerable time for youth with chronic diseases. In youth with rheumatic disease, studies show high rates of loss to follow up and increased disease activity. Howev... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 30, 2020 Category: Rheumatology Authors: Paul T. Jensen, Keumseok Koh, Rebecca E. Cash, Stacy P. Ardoin and Ayaz Hyder Tags: Research article Source Type: research

Importance of pediatric rheumatologists and transitional care for juvenile idiopathic arthritis-associated uveitis: a retrospective series of 9 cases
Juvenile idiopathic arthritis-associated uveitis (JIA-U) is a serious condition associated with the risk of blindness. However, pediatric rheumatologists rarely encounter cases of blindness, because most patie... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 23, 2020 Category: Rheumatology Authors: Susumu Yamazaki, Asami Shimbo, Yuko Akutsu, Hiroshi Takase, Tomohiro Morio and Masaaki Mori Tags: Case Report Source Type: research

Assessment of traditional and non-traditional risk factors for premature atherosclerosis in children with juvenile dermatomyositis and pediatric controls
Children with juvenile dermatomyositis (JDM), the most common inflammatory myopathy of childhood, may be at increased risk of premature atherosclerosis given a host of traditional and non-traditional risk fact... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 18, 2020 Category: Rheumatology Authors: Dawn M. Wahezi, Emily J. Liebling, Jaeun Choi, Marija Dionizovik-Dimanovski, Qi Gao and Jillian Parekh Tags: Research article Source Type: research

The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease
The calcineurin and nuclear factor of activated T-cells (CaN-NFAT) signaling pathway had been found to be associated with Kawasaki disease (KD) susceptibility and coronary artery aneurysm formation as a contri... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 17, 2020 Category: Rheumatology Authors: Yameng Sun, Jingjing Liu, Zhimin Geng, Yijing Tao, Fenglei Zheng, Ying Wang, Songling Fu, Wei Wang, Chunhong Xie, Yiying Zhang and Fangqi Gong Tags: Research article Source Type: research

A case of rectal ulcers during aspirin therapy in acute Kawasaki disease
Kawasaki disease (KD) is an acute febrile multisystem vasculitis and has been recognized to be one of the most common causes of acquired heart disease in children. Although gastrointestinal symptoms including ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 17, 2020 Category: Rheumatology Authors: Yong Han, Chenmin Hu and Yanping Yu Tags: Letter to the Editor Source Type: research

Patient factors associated with waiting time to pediatric rheumatologist consultation for patients with juvenile idiopathic arthritis
Early diagnosis and treatment of Juvenile Idiopathic Arthritis (JIA) is essential to optimize outcomes. Wait times (WTs) to consultation with a pediatric rheumatologist consultation is a Canadian quality measu... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 6, 2020 Category: Rheumatology Authors: Claire E. H. Barber, Cheryl Barnabe, Susanne Benseler, Ricky Chin, Nicole Johnson, Nadia Luca, Paivi Miettunen, Marinka Twilt, Dwaraka Veeramreddy, Natalie J. Shiff and Heinrike Schmeling Tags: Research article Source Type: research

Factors impacting referral of JIA patients to a tertiary level pediatric rheumatology center in North India: a retrospective cohort study
JIA studies demonstrate that there is a “window of opportunity” early in the disease course during which appropriate management improves outcomes. No data is available regarding patients’ pathway, before first... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 4, 2020 Category: Rheumatology Authors: Manjari Agarwal, Caroline Freychet, Sumidha Jain, Abhay Shivpuri, Anju Singh, Veronique Dinand and Sujata Sawhney Tags: Research article Source Type: research

Expert panel consensus recommendations for diagnosis and treatment of secondary osteoporosis in children
Osteoporosis incidence in children is increasing due to the increased survival rate of patients suffering from chronic diseases and the increased use of drugs that can damage bones. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 24, 2020 Category: Rheumatology Authors: Roc ío Galindo-Zavala, Rosa Bou-Torrent, Berta Magallares-López, Concepción Mir-Perelló, Natalia Palmou-Fontana, Belén Sevilla-Pérez, Marta Medrano-San Ildefonso, Mª. Isabel González-Fernández, Almudena Román-Pascual, Paula Alcañiz-Rodríguez, Tags: Research article Source Type: research

Maintenance of antibody response to diphtheria/tetanus vaccine in patients aged 2 –5 years with polyarticular-course juvenile idiopathic arthritis receiving subcutaneous abatacept
Patients with polyarticular-course juvenile idiopathic arthritis (pJIA), receiving disease-modifying anti-rheumatic drugs with immunosuppressive effects, may be at increased risk of vaccine-preventable infecti... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 22, 2020 Category: Rheumatology Authors: Hermine I. Brunner, Nikolay Tzaribachev, Gabriel Vega Cornejo, Rik Joos, Elisabeth Gervais, Rolando Cimaz, Inmaculada Calvo Penad és, Rubén Cuttica, Thomas Lutz, Pierre Quartier, Yash Gandhi, Marleen Nys, Robert Wong, Alberto Martini, Daniel J. Lovell a Tags: Short Report Source Type: research

Correction to: Biomarkers associating endothelial dysregulation in pediatric-onset systemic lupus erythematous
Following publication of the original article [1], we have been notified that the colour representation of the graph is not correct in Figure 6 legend. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 18, 2020 Category: Rheumatology Authors: Wan-Fang Lee, Chao-Yi Wu, Huang-Yu Yang, Wen-I Lee, Li-Chen Chen, Liang-Shiou Ou and Jing-Long Huang Tags: Correction Source Type: research

Consensus protocols for the diagnosis and management of the hereditary autoinflammatory syndromes CAPS, TRAPS and MKD/HIDS: a German PRO-KIND initiative
Rare autoinflammatory diseases (AIDs) including Cryopyrin-Associated Periodic Syndrome (CAPS), Tumor Necrosis Receptor-Associated Periodic Syndrome (TRAPS) and Mevalonate Kinase Deficiency Syndrome (MKD)/ Hype... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 17, 2020 Category: Rheumatology Authors: Sandra Hansmann, Elke Lainka, Gerd Horneff, Dirk Holzinger, Nikolaus Rieber, Annette F. Jansson, Angela R ösen-Wolff, Gabi Erbis, Martina Prelog, Juergen Brunner, Susanne M. Benseler and Jasmin B. Kuemmerle-Deschner Tags: Research article Source Type: research

Correction to: Pain, functional disability, and their Association in Juvenile Fibromyalgia Compared to other pediatric rheumatic diseases
Following publication of the original article [1], we have been notified that the corresponding author ’s given name is spelled incorrectly. The given name, thus, should be as follows: (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 12, 2020 Category: Rheumatology Authors: Mark Connelly and Jennifer E. Weiss Tags: Correction Source Type: research

Adolescent Sjogren ’s syndrome presenting as psychosis: a case series
Neurological involvement has been reported in up to 80% of adults with Primary Sjogren ’s syndrome (pSS) with psychiatric abnormalities including anxiety, depression, and cognitive dysfunction being common. Psy... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 11, 2020 Category: Rheumatology Authors: Erin K. Hammett, Cristina Fernandez-Carbonell, Courtney Crayne, Alexis Boneparth, Randy Q. Cron and Suhas M. Radhakrishna Tags: Case Report Source Type: research

Correction to: Proposal for a definition for response to treatment, inactive disease and damage for JIA associated uveitis based on the validation of a uveitis related JIA outcome measures from the Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC)
Following publication of the original article [1], we have been notified that the author Joan Calzada should not have been included to the team of authors. The authors ’ team, thus, should be as follows: (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 11, 2020 Category: Rheumatology Authors: Ivan Foeldvari, Jens Klotsche, Gabriele Simonini, Clive Edelsten, Sheila T. Angeles-Han, Regitze Bangsgaard, Joke de Boer, Gabriele Brumm, Rosa Bou Torrent, Tamas Constantin, Cinzia DeLibero, Jesus Diaz, Valeria Maria Gerloni, Margarida Guedes, Arnd Heili Tags: Correction Source Type: research

Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance
Methotrexate (MTX) therapy has proven to be a successful and safe treatment for Juvenile Idiopathic Arthritis (JIA). Despite the high efficacy rates of MTX, treatment outcomes are often complicated by burdenso... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 7, 2020 Category: Rheumatology Authors: Rosanne M. Smits, Dieuwke S. Veldhuijzen, Henriet van Middendorp, Petra C. E. Hissink Muller, Wineke Armbrust, Elizabeth Legger, Nico M. Wulffraat and Andrea W. M. Evers Tags: Hypothesis Source Type: research

Children ’s fear of needle injections: a qualitative study of training sessions for children with rheumatic diseases before home administration
Treatment of rheumatic diseases in children often includes long-term needle injections, which represent a risk for refusing medication based on potential needle-fear. How nurses manage children ’s fear and pain... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 7, 2020 Category: Rheumatology Authors: Kari S ørensen, Helge Skirbekk, Gunnvald Kvarstein and Hilde Wøien Tags: Research article Source Type: research