Lung involvement in children with newly diagnosed rheumatic diseases: characteristics and associations
Pulmonary complications of rheumatic diseases may cause functional impairment and increase mortality. However, reports regarding detection of lung involvement in children with treatment-naive, newly diagnosed ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 20, 2022 Category: Rheumatology Authors: Hua Huang, Yabin Hu, Yufen Wu, Fei Ding, Xuemei Xu, Yingying Jin, Yanliang Jin and Yixiao Bao Tags: Research article Source Type: research

Humoral and cellular immune response to mRNA SARS-CoV-2 BNT162b2 vaccine in adolescents with rheumatic diseases
Data about safety and efficacy of the mRNA SARS-CoV-2 vaccine in adolescents with rheumatic diseases (RD) is scarce and whether these patients generate a sufficient immune response to the vaccine remains an ou... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 13, 2022 Category: Rheumatology Authors: Clara Udaondo, Carmen C ámara, Laura Miguel Berenguel, Rosa Alcobendas Rueda, Celia Muñoz Gómez, Claudia Millán Longo, Blanca Díaz – Delgado, Iker Falces-Romero, Mariana Díaz Almirón, Jordi Ochando, Ana Méndez – Echevarría, Agustín Remesal C Tags: Research article Source Type: research

A case of ANCA-associated vasculitis in a 16-year-old female following SARS-COV-2 infection and a systematic review of the literature
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare form of vasculitis in children. SARS-CoV-2, the virus that causes COVID-19 infection, seems to trigger autoimmunity and new-onse... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 13, 2022 Category: Rheumatology Authors: Maria C. Bryant, L. Terry Spencer and Ali Yalcindag Tags: Case Report Source Type: research

α2-fraction and haptoglobin as biomarkers for disease activity in oligo- and polyarticular juvenile idiopathic arthritis
Unlike in adult rheumatology, for most forms of juvenile idiopathic arthritis (JIA) no reliable biomarkers currently exist to assess joint and disease activity. However, electrophoresis is frequently found cha... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 13, 2022 Category: Rheumatology Authors: Ludwig Zeller, Pascal N. Tyrrell, Stella Wang, Nadine Fischer, Johannes-Peter Haas and Boris H ügle Tags: Research article Source Type: research

Tapering of biological treatment in autoinflammatory diseases: a scoping review
Biological treatment and treat-to-target approaches guide the achievement of inactive disease and clinical remission in Autoinflammatory Diseases (AID). However, there is limited evidence addressing optimal ta... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 13, 2022 Category: Rheumatology Authors: Tatjana Welzel, Lea Oefelein, Marinka Twilt, Marc Pfister, Jasmin B. Kuemmerle-Deschner and Susanne M. Benseler Tags: Review Source Type: research

Characteristics and genetic analysis of patients suspected with early-onset systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is rarely diagnosed before 5-years-old. Those with disease onset at a very young age are predicted by a higher genetic risk and a more severe phenotype. We performed whole-ex... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 13, 2022 Category: Rheumatology Authors: Wan-Fang Lee, Wen-Lang Fan, Min-Hua Tseng, Huang-Yu Yang, Jing-Long Huang and Chao-Yi Wu Tags: Case Report Source Type: research

Comment on: a novel transition clinic structure for adolescent and young adult patients with childhood onset rheumatic disease improves transition outcomes
(Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 9, 2022 Category: Rheumatology Authors: Mislav Radi ć Tags: Letter to the Editor Source Type: research

Feasibility of quantitative sensory testing in juvenile idiopathic arthritis
Juvenile Idiopathic Arthritis (JIA) is a childhood-rheumatic disease with pain as a major early complaint, and in 10 –17% pain remains a major symptom. Very few data exist on sensory threshold changes at the kn... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 9, 2022 Category: Rheumatology Authors: Maarten O. Mensink, Niels Eijkelkamp, Dieuwke S. Veldhuijzen and Nico M. Wulffraat Tags: Research article Source Type: research

Successful rituximab treatment for severe rapidly progressive interstitial lung disease with anti-MDA5 antibody-positive juvenile dermatomyositis: a case report and literature review
Rapidly progressive (RP) interstitial lung disease (ILD) is a life-threatening complication of juvenile dermatomyositis (JDM); however, it is generally refractory to treatment; to the best of our knowledge, no... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 4, 2022 Category: Rheumatology Authors: Kentaro Nishi, Masao Ogura, Naotaka Tamai, Naofumi Gima, Kentaro Ide, Goro Koinuma, Koichi Kamei and Shuichi Ito Tags: Case Report Source Type: research

Clinical observations on infliximab treatment of infantile onset Takayasu arteritis
There is insufficient evidence on the clinical effectiveness and safety of infliximab (IFX) treatment of Takayasu arteritis (TA) in infants. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - August 4, 2022 Category: Rheumatology Authors: Min Kang, Jianming Lai, Dan Zhang, Yingjie Xu, Jia Zhu and Ming Li Tags: Research article Source Type: research

Latent classes of early response trajectories to biologics initiation in juvenile idiopathic arthritis: an analysis of four trials
1) To delineate latent classes of treatment response to biologics in juvenile idiopathic arthritis (JIA) patients in the first 16  weeks after initiation. 2) To identify predictors of early disease response. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 30, 2022 Category: Rheumatology Authors: Lily Siok Hoon Lim, Shamsia Shobhan, Armend Lokku, Sarah Ringold and Eleanor Pullenayegum Tags: Research article Source Type: research

Is an association of acro-osteolysis, bone fragility, and enchondromatosis a newfound disease caused by an amplification of PTHLH? A case report
Acro-osteolysis (AO) refers to resorption of the distal finger and toe phalanges. It displays two patterns: (i) diffuse AO and (ii) transverse or bandlike AO. AO can be a sign of local distress (e.g. of toxic ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 30, 2022 Category: Rheumatology Authors: St éphane Echaubard, Céline Pebrel-Richard, Aurélie Chausset, Jean-Louis Kemeny, Etienne Merlin and Fanny Laffargue Tags: Case Report Source Type: research

Bilateral anterior and intermediate uveitis in SARS-CoV-2 associated multisystem inflammatory syndrome in a pediatric patient
To report a case of bilateral anterior intermediate uveitis after recovery from SARS-CoV-2 associated multisystem inflammatory syndrome in children (MIS-C). (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 30, 2022 Category: Rheumatology Authors: Jessica Shantha, Amit K. Reddy, Amol Sura, Adrian Tsang, Kareem Moussa, Nisha Acharya, John Gonzales and Thuy Doan Tags: Case Report Source Type: research

Glucose metabolism in systemic juvenile idiopathic arthritis
Systemic juvenile idiopathic arthritis (SJIA) is a chronic systemic inflammatory disease in children. Overproduction of inflammatory cytokines in SJIA resembles that in adult onset Still disease. Chronic infla... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 29, 2022 Category: Rheumatology Authors: Papatsorn Suppasit, Soamarat Vilaiyuk, Preamrudee Poomthavorn, Sarunyu Pongratanakul, Patcharin Khlairit and Pat Mahachoklertwattana Tags: Research article Source Type: research

The efficacy and safety of allogeneic stem cell transplantation in Mevalonate Kinase Deficiency
Mevalonate kinase deficiency (MKD) is a rare autoinflammatory syndrome. Several reports have described allogeneic hematopoietic stem cell transplantation in severely affected patients, sometimes with promising... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 29, 2022 Category: Rheumatology Authors: Jerold Jeyaratnam, Maura Faraci, Andrew R. Gennery, Katarzyna Drabko, Mattia Algeri, Akira Morimoto, Tiarlan Sirait, Arjan C. Lankester, Michael Albert, Benedicte Neven and Joost Frenkel Tags: Research article Source Type: research