Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients
The plasticity of T helper-17 (Th17) and regulatory T (Treg) cells may be a clue to pathogenesis of Juvenile Idiopathic Arthritis (JIA). It is still unclear, whether targeted suppression of Interleukin (IL)-17... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 11, 2022 Category: Rheumatology Authors: Marie-Therese Holzer, Giovanni Almanzar, Robert Woidich, Boris H ügle, Johannes-Peter Haas and Martina Prelog Tags: Research article Source Type: research

In pediatric rheumatologic disease, methotrexate leads to mildly changed bloodwork on the second day after administration
(Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 7, 2022 Category: Rheumatology Authors: Boris Hugle, Nadine Fischer and Johannes-Peter Haas Tags: Letter to the Editor Source Type: research

Challenging the silent temporomandibular joint paradigm in children with juvenile idiopathic arthritis
(Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - April 2, 2022 Category: Rheumatology Authors: Willemijn F. C. de Sonnaville, Michel H. Steenks, Caroline M. Speksnijder, Nico M. Wulffraat and Antoine J. W. P. Rosenberg Tags: Letter to the Editor Source Type: research

Feasibility of the wingate anaerobic exercise test as a clinical measure in patients with juvenile dermatomyositis
Core sets, while widely adopted for clinical assessment in juvenile dermatomyositis (JDM), have some drawbacks – they are time consuming, were developed primarily for research, and require an experienced multi... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 28, 2022 Category: Rheumatology Authors: Saunya Dover, Samantha Stephens, Hayyah Clairman, Andrew Abesamis, Omidali Aghababaei Jazi, Stephanie Babij, Jo-Anne Marcuz, Natasha Naraidoo, Jing Pan, Eleanor Pullenayegum, Dax Rumsey, Kristi Whitney and Brian M. Feldman Tags: Research article Source Type: research

Rheumatic fever in a developed country – is it still relevant? A retrospective, 25 years follow-up
Our aims were to clinically and epidemiologically characterize rheumatic fever (RF) in the current era in Israel. Although there has been a steady decline in the incidence of RF in the western world, evidence ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - March 15, 2022 Category: Rheumatology Authors: Rotem Tal, Mohamad Hamad Saied, Razi Zidani, Yoel Levinsky, Rachel Straussberg, Jacob Amir, Gil Amarilyo and Liora Harel Tags: Research article Source Type: research