Evidence of persistent glial cell dysfunction in the anterior cingulate cortex of juvenile idiopathic arthritis children: a proton MRS study
This study aims to investigate whether the neurometabolites of the anterior cingulate cortex (ACC) were distinct in patients with active and inactive juvenile idiopathic arthritis (JIA) using the proton magnet... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 27, 2022 Category: Rheumatology Authors: Haiwei Han, Ji Hong Xiao, Yifei Weng, Hongyan Liang, Chengkun Han, Cuili Yi, Kezhao Lin and Hua Wu Tags: Research article Source Type: research

Bone remodeling serum markers in children with systemic lupus erythematosus
SLE is an autoimmune multisystem disease. Glucocorticoid is an irreplaceable medication for SLE. Glucocorticoid and inflammatory mediators impact bone remodeling by OPG/RANKL/RANK signal system, which could le... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 27, 2022 Category: Rheumatology Authors: Sheng Hao, Jing Zhang, Bingxue Huang, Dan Feng, Xiaoling Niu and Wenyan Huang Tags: Research article Source Type: research

Factors associated with care- and health-related quality of life of caregivers of children with juvenile idiopathic arthritis
This study investigates the relationship of child, caregiver, and caring context measurements with the care-related quality of life (CRQoL) and health-related quality of life (HRQoL) of caregivers of children ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 23, 2022 Category: Rheumatology Authors: Luiza R. Grazziotin, Gillian Currie, Marinka Twilt, Maarten J. IJzerman, Michelle M. A. Kip, Hendrik Koffijberg, Gouke Bonsel, Susanne M. Benseler, Joost F. Swart, Sebastiaan J. Vastert, Nico M. Wulffraat, Rae S. M. Yeung, Wineke Armbrust, J. Merlijn van Tags: Research article Source Type: research

Modified Delphi study to identify priority clinical questions for the Australian living guidelines for the management of Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is the most common rheumatic inflammatory disease in childhood. Optimal management requires clinicians to be up to date with the rapidly evolving evidence base. ‘Living’ evi... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 23, 2022 Category: Rheumatology Authors: Georgina Tiller, William D. Renton, Joachim Tan, Samuel Whittle, Jodie Avery, Jane Munro and Rachelle Buchbinder Tags: Research article Source Type: research

Baseline characteristics of children with juvenile dermatomyositis enrolled in the first year of the new Childhood Arthritis and Rheumatology Research Alliance registry
To report baseline characteristics, patient reported outcomes and treatment of children with Juvenile Dermatomyositis (JDM) in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 19, 2022 Category: Rheumatology Authors: Jessica Neely, Kaveh Ardalan, Adam Huber and Susan Kim Tags: Research article Source Type: research

Musculoskeletal pain and its effect on daily activity and behaviour in Icelandic children and youths with juvenile idiopathic arthritis: a cross-sectional case-control study
Juvenile idiopathic arthritis is characterised by recurring episodes of acute inflammation, with joint swelling in one or more joints, often accompanied by pain. These episodes can now be controlled better tha... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 15, 2022 Category: Rheumatology Authors: Svanhildur Arna Oskarsdottir, Audur Kristjansdottir, Judith Amalia Gudmundsdottir, Solrun W. Kamban, Zinajda Alomerovic Licina, Drifa Bjork Gudmundsdottir and Bjorg Gudjonsdottir Tags: Research article Source Type: research

PSTPIP1-associated myeloid-related proteinaemia inflammatory (PAMI) syndrome; a case presenting as a perinatal event with early central nervous system involvement?
We report a three-year-old girl with a potentially unique phenotype of perinatal onset and neurovascular features who was found to have PAMI syndrome. We also compare her case to those previously reported and ... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 15, 2022 Category: Rheumatology Authors: Bethany Gillies Whiteside, Hannah Titheradge and Eslam Al-Abadi Tags: Case Report Source Type: research

PFAPA flares observed during COVID outbreak: can emotional stress trigger PFAPA attacks? A multicenter cohort study
It is common knowledge among clinicians who treat PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis) patients that emotional stress can trigger PFAPA attacks similarly to other autoinflammatory... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 8, 2022 Category: Rheumatology Authors: Yoel Levinsky, Yonatan Butbul Aviel, Sabreen Abu Ahmad, Mor Broide, Yulia Gendler, Neta Dagan, Michal Gafner, Hadar Gavra, Shelly Kagan, Kfir Kedar, Hamada Mohammad Natour, Rotem Tal, Tamar Veres, Gil Amarilyo and Liora Harel Tags: Research article Source Type: research

Uveitis associated with juvenile arthritis: a continued cohort study 40  years after uveitis onset
A third follow-up study, mean 40.7  years after uveitis onset, of a cohort originally consisting of 55 Swedish patients with uveitis associated with juvenile arthritis. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - July 8, 2022 Category: Rheumatology Authors: Angelika Skarin, Elisabet Berthold, Ola Rauer and Elisabeth Bengtsson-Stigmar Tags: Research article Source Type: research

Association of juvenile idiopathic arthritis with maternal infection: a case control study
Maternal infection has been posited as a risk factor for childhood autoimmune disease such as type I diabetes. Given that similar studies in JIA are scant, our objective was to evaluate the association between... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 23, 2022 Category: Rheumatology Authors: Anna Sutton, Sabah M. Quraishi and Susan Shenoi Tags: Short Report Source Type: research

Quality improvement in juvenile idiopathic arthritis: a mixed-methods implementation pilot of the CAPTURE-JIA dataset
A significant proportion of children and young people with juvenile idiopathic arthritis (JIA) do not achieve inactive disease during the first two years following diagnosis. Refinements to clinical care pathw... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 18, 2022 Category: Rheumatology Authors: Flora McErlane, Chris Anderson, Saskia Lawson-Tovey, Barbara Lee, Chris Lee, Laura Lunt, Janet E. McDonagh, Andrew D. Smith, Nicola Smith and Gavin Cleary Tags: Research article Source Type: research

Monogenic disorders as mimics of juvenile idiopathic arthritis
Juvenile idiopathic arthritis is the most common chronic rheumatic disease of childhood. The term JIA encompasses a heterogenous group of diseases. The variability in phenotype of patients affected by the dise... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 18, 2022 Category: Rheumatology Authors: Laura Furness, Phil Riley, Neville Wright, Siddharth Banka, Stephen Eyre, Adam Jackson and Tracy A. Briggs Tags: Case Report Source Type: research

Myeloid-related protein 8/14 in plasma and serum in patients with new-onset juvenile idiopathic arthritis in real-world setting in a single center
The aim of this study was to analyze the usefulness of myeloid-related protein 8/14 (MRP8/14) in the prediction of disease course in a real-world setting for patients with new-onset juvenile idiopathic arthrit... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 16, 2022 Category: Rheumatology Authors: Paula L. Keskitalo, Salla M. Kangas, Sirja Sard, Tytti Pokka, Virpi Glumoff, Petri Kulmala and Paula V ähäsalo Tags: Research article Source Type: research

Chronic nonbacterial osteomyelitis in children: a multicentre Belgian cohort of 30 children
To evaluate clinical characteristics, imaging findings, therapeutic approach and outcome of paediatric patients with Chronic Non-Bacterial Osteomyelitis (CNO). (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 13, 2022 Category: Rheumatology Authors: Sara Kaut, Ine Van den Wyngaert, Davy Christiaens, Carine Wouters, Nathalie Noppe, Nele Herregods, Joke Dehoorne and Lien De Somer Tags: Research article Source Type: research

Dengue infection triggered immune mediated necrotizing myopathy in children: a case report and literature review
Immune-mediated necrotizing myopathy (IMNM) is a subgroup of idiopathic inflammatory myopathies manifesting with progressive weakness, elevated serum creatine kinase (CK) levels, and necrotizing myopathic feat... (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - June 7, 2022 Category: Rheumatology Authors: Aphirak Mekmangkonthong, Jakkrit Amornvit, Numphung Numkarunarunrote, Montida Veeravigrom and Parichat Khaosut Tags: Case Report Source Type: research