Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: Mol Biol Cell - April 18, 2024 Category: Molecular Biology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
Cretan HLA genetics supports its early Minoan culture as a link between North Africa and Europe
Hum Immunol. 2024 Apr 17:110799. doi: 10.1016/j.humimm.2024.110799. Online ahead of print.ABSTRACTHLA studies in Crete show that this population is related to North Africans and also Iberians. This may be a reflection of a common prehistoric first Europeans relationships with North Africans and drying Saharan emigration after 10,000 years BC; it may be specifically represented by a primitive and early cult to the bull in both Cretan (Minoan) and Iberian populations. In the present study, unrelated Cretans representing different Island parts have been studied for class II HLA-DRB1 and -DQB1 alleles. The most frequent ones w...
Source: Human Immunology - April 18, 2024 Category: Allergy & Immunology Authors: Antonio Arnaiz-Villena Ignacio Juarez Christian Vaquero-Yuste Tomas Lledo Jose Manuel Martin-Villa Fabio Suarez-Trujillo Source Type: research
Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
Cretan HLA genetics supports its early Minoan culture as a link between North Africa and Europe
Hum Immunol. 2024 Apr 17:110799. doi: 10.1016/j.humimm.2024.110799. Online ahead of print.ABSTRACTHLA studies in Crete show that this population is related to North Africans and also Iberians. This may be a reflection of a common prehistoric first Europeans relationships with North Africans and drying Saharan emigration after 10,000 years BC; it may be specifically represented by a primitive and early cult to the bull in both Cretan (Minoan) and Iberian populations. In the present study, unrelated Cretans representing different Island parts have been studied for class II HLA-DRB1 and -DQB1 alleles. The most frequent ones w...
Source: Human Immunology - April 18, 2024 Category: Allergy & Immunology Authors: Antonio Arnaiz-Villena Ignacio Juarez Christian Vaquero-Yuste Tomas Lledo Jose Manuel Martin-Villa Fabio Suarez-Trujillo Source Type: research
The chemical composition of the aerial parts' essential oil of < em > Limonium lobatum < /em > (L.f.) Chaz. growing wild in Algeria
Nat Prod Res. 2024 Apr 16:1-8. doi: 10.1080/14786419.2024.2342001. Online ahead of print.ABSTRACTThe Limonium genus (Plumbaginaceae) includes several species of perennial herbs and shrubs belonging to a particular type of halophytes, known as 'recretohalophytes'. Limonium species are widely distributed in the Mediterranean region, mainly in the North-Eastern and Southern countries and several bioactivities have been well documented. In the present study, the chemical composition of the essential oil (EO) of the aerial parts of Limonium lobatum (L.f.) Chaz., a species never chemically previously studied and collected in Alg...
Source: Natural Product Research - April 16, 2024 Category: Biochemistry Authors: Larbi Derbak Natale Badalamenti Khellaf Rebbas Bendif Hamdi Maurizio Bruno Source Type: research
A sulfated exopolysaccharide derived from Chlorella sp. exhibiting in vitro anti- α-D-Glucosidase activity
This study aimed to isolate a polysaccharide-producing microalga from an extreme ecosystem and to evaluate its capacity to inhibit the α-D-glucosidase enzyme. Chlorella strain is isolated from hypersaline Lake in the Algerian desert. The exopolysaccharide extraction was performed by the concentration of free-cell supernatant in a rotary evaporator. The infrared analysis showed a characteristic footprint of carbohydrates with particular functional groups, such as sulfate. Gas chromatography-mass spectrometry has revealed a hetero-exopolysaccharide composed of galactose 35.75%, glucose 21.13%, xylose 16.81%, fructose 6.96%,...
Source: Archives of Microbiology - April 16, 2024 Category: Microbiology Authors: Karima Guehaz Zakaria Boual Alia Telli Hicham Meskher Hakim Belkhalfa Guillaume Pierre Philippe Michaud Alessandra Adessi Source Type: research
News at a glance: Jailed conservationists freed, physics titan dies, and diversity in anatomical illustrations
ASTRONOMY
Scientists flock to the eclipse
Tens of millions in North America turned their specially protected eyes to the skies on 8 April for several minutes of darkness when the Moon blocked the disk of the Sun, casting a shadow across Mexico, 15 U.S. states, and Canada. Researchers and citizen scientists seized the opportunity to study the corona—the wispy, outer layer of the Sun’s atmosphere—from the ground and in eclipse-chasing aircraft. They expected to see loops of plasma and other solar flares because the eclipse coincided with solar maximum, a period of high magnetic activity. Research...
Source: Science of Aging Knowledge Environment - April 11, 2024 Category: Geriatrics Source Type: research
Removal of malachite green from aqueous solution by kerolite/stevensite mixed-layer clay: full factorial design analysis
. (Source: International Journal of Environmental Analytical Chemistry)
Source: International Journal of Environmental Analytical Chemistry - April 11, 2024 Category: Chemistry Authors: Yassine BounouriMadjid BerkaniNabila HaddakMeriem IdireneSalima ZatoutSaloua TensaoutGhania FouraChafika MezitiSalima Harounea Facult é des Sciences Exactes, Laboratoire de Physico-chimie des Matériaux et Catalyse, Université de Bejaia, Bejaia, Algeria Source Type: research
The frequencies distribution of CYP3A5 rs776746 and ABCB1 rs1045642 polymorphisms in the west Algerian population and relationships with pharmacogenetics
Conclusion: The difference in the allelic and genotypic distribution of these polymorphisms emphasize the need for dose adjustmentsin drugs metabolized by CYP3A5 and transported by ABCB1 to optimize treatments outcomes.Keywords: CYP3A5; ABCB1; genetic polymorphism; pharmacogenetics; West Algeria. (Source: African Health Sciences)
Source: African Health Sciences - April 8, 2024 Category: African Health Authors: Amina Ammour, Meriem Aberkane, Abdallah Boudjema, Wefa Boughrara, Sounnia Mediene Benchekor Source Type: research
News at a glance: Giant telescope camera complete, limits to Paxlovid benefits, and missing battlefield bones
ASTRONOMY
Biggest ever digital camera heads to Chile
Skip slideshow
Researchers at the SLAC National Accelerator Laboratory have finished building the biggest ever astronomical camera. It will create a movie of the universe, imaging the whole southern sky in unprecedented detail every 3 days.
Jacqueline Ramseyer Orrell/SLAC National Accelerator Laboratory
Researchers install the first of 21 arrays of image sensors that together make up the camer...
Source: Science of Aging Knowledge Environment - April 4, 2024 Category: Geriatrics Source Type: research
Epidemiological insights into colorectal cancer in northwestern Algeria
CONCLUSION: This study may provide a comprehensive glimpse into CRC epidemiology in northwest Algeria. Understanding regional differences is the key to implementing specific preventive and interventional strategies.PMID:38566765 | PMC:PMC10984843 | DOI:10.3332/ecancer.2024.1684 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - April 3, 2024 Category: Cancer & Oncology Authors: Salah Eddine El Herrag Soraya Moulessehoul Douniazad El Mehadji Djamila Yekrou M éghit Boumediène Khaled Source Type: research
Évaluation pharmaco-économique de la transplantation rénale à l’établissement hospitalier et universitaire d’Oran : analyse des coûts et implications
CONCLUSION: This study estimated the cost of kidney transplantation at the UHEO and revealed that the cost of the first year is the most important due to many factors. It also showed that costs tend to decrease with the age of the transplant and the clinical stability of the recipient.PMID:38567524 | DOI:10.1684/ndt.2024.72 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - April 3, 2024 Category: Urology & Nephrology Authors: Mohamed Sadeg Amine Amarni Habiba Fetati Kada Djoudad Brahim Bendifallah Faiza Zerdoumi Houari Toumi Source Type: research
Factors associated with therapeutic non-adherence in renal transplant patients: a bicentric study in Algeria
CONCLUSION: The findings of this study highlight concerning therapeutic adherence among kidney transplant recipients, emphasizing the crucial importance of therapeutic education to improve treatment adherence and underscoring the need to integrate these factors into clinical patient management.PMID:38567520 | DOI:10.1684/ndt.2024.69 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - April 3, 2024 Category: Urology & Nephrology Authors: Akli Islem Chebli Zeyneb Chelighem Emad Shalabi Younes Zebbiche Nada Boubidi Bahi Baraa Nechoia Boumalha Djihad Bouhlassa Sara Abdennour Source Type: research
