Phytochemical profile, < em > in vitro < /em > antioxidant and antibacterial activities of different extracts of an Algerian endemic: < em > Teucrium atratum < /em >
Nat Prod Res. 2024 Apr 22:1-10. doi: 10.1080/14786419.2024.2340758. Online ahead of print.ABSTRACTTeucrium atratum Pomel. is a species belonging to the Lamiaceae family used in Algerian folk medicine. The present work essentially aimed to assess the phenolic composition and to evaluate some of the biological effects of different extracts, never previously studied, of T. atratum growing in Algeria. High levels of total phenolic and flavonoids were recorded in the hydromethanolic extract. Chlorogenic acid, isoquercetin, coumarin, cinnamic acid, quercetin dihydrate, and catechin were identified in the methanolic extract by me...
Source: Natural Product Research - April 22, 2024 Category: Biochemistry Authors: Nina Sadou Lynda Gali Ratiba Seridi Maurizio Bruno Hamdi Bendif Source Type: research
Harnessing artificial intelligence-driven approach for enhanced indole-3-acetic acid from the newly isolated Streptomyces rutgersensis AW08
This study aims to select a high IAA-producing Streptomyces-like strain isolated from Lake Oubeira sediments (El Kala, Algeria) for further investigations (i.e., 16S rRNA gene barcoding and process optimization). Subsequently, artificial intelligence-based approaches were employed to maximize IAA bioproduction on spent coffee grounds as high-value-added feedstock. The specificity was the novel application of the Limited-Memory Broyden-Fletcher-Goldfarb-Shanno Box (L-BFGS-B) optimization algorithm. The new strain AW08 was a significant producer of IAA (26.116 ± 0.61 μg/mL) and was identified as Streptomyces rutgersensis b...
Source: Environmental Research - April 20, 2024 Category: Environmental Health Authors: Wiem Alloun Mohammed Berkani Amin Shavandi Adl ène Beddiar Marika Pellegrini Matteo Garzia Delloula Lakhdari Sharanabasava V Ganachari Tejraj M Aminabhavi Yasser Vasseghian Uday Muddapur Noreddine Kacem Chaouche Source Type: research
Tumor necrosis factor alpha induced protein 3, interleukin 10, tumor necrosis factor alpha, and interleukin 17 F genes polymorphisms in Algerian patients with rheumatoid arthritis
CONCLUSION: Our results show that there is a tendency for the AG genotype of IL10-1082 to be associated with the production of ACPA in patients with RA. None of the variants studied were associated with RA susceptibility in Algerians.PMID:38642181 | DOI:10.1007/s11033-024-09525-2 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 20, 2024 Category: Molecular Biology Authors: D Benahmed M Abbadi D Zaoui H Ait Hamoudi W Boukouaci S Bouguerra-Aouichat S S Salah Source Type: research
Thymus algeriensis Boiss. et Reut., a north African endemic plant species: genetic diversity and population structure as assessed by molecular markers, a pioneer step for conservation implications
CONCLUSIONS: The used molecular markers (ISSRs and SSRs) seem to be effective in deciphering genetic polymorphism of Tunisian genotypes of T. algeriensis. Therefore, the genetic structure of the studied genotypes could constitute a starting point for further conservation, characterization and breeding programs.PMID:38642172 | DOI:10.1007/s11033-024-09473-x (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 20, 2024 Category: Molecular Biology Authors: Imen Ben Elhadj Ali Islem Yangui Anhar Raadani Arbi Guetat Soumaya Hmissi Jih ène Flihi Mohamed Boussaid Chokri Messaoud Source Type: research
High-temperature CO < sub > 2 < /sub > sorption over Li < sub > 4 < /sub > SiO < sub > 4 < /sub > synthesized from diatomite: study of sorption heat and isotherm modeling
Environ Sci Pollut Res Int. 2024 Apr 20. doi: 10.1007/s11356-024-33332-8. Online ahead of print.ABSTRACTThe Li4SiO4 seems to be an excellent sorbent for CO2 capture at post-combustion. Our work contributes to understanding the effect of the natural Algerian diatomite as a source of SiO2 in the synthesis of Li4SiO4 for CO2 capture at high temperature. For this purpose, we use various molar % (stoichiometric and excess) of calcined natural diatomite and pure SiO2. To select the best composition, CO2 sorption isotherms at 500 °C on the prepared Li4SiO4 are obtained using TGA measurements under various flows of CO2 in N2. The...
Source: Environmental Science and Pollution Research International - April 20, 2024 Category: Environmental Health Authors: Khedidja Messabih Nadia Bendjaballah-Lalaoui Youcef Boucheffa Source Type: research
Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: Mol Biol Cell - April 18, 2024 Category: Molecular Biology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
Cretan HLA genetics supports its early Minoan culture as a link between North Africa and Europe
Hum Immunol. 2024 Apr 17:110799. doi: 10.1016/j.humimm.2024.110799. Online ahead of print.ABSTRACTHLA studies in Crete show that this population is related to North Africans and also Iberians. This may be a reflection of a common prehistoric first Europeans relationships with North Africans and drying Saharan emigration after 10,000 years BC; it may be specifically represented by a primitive and early cult to the bull in both Cretan (Minoan) and Iberian populations. In the present study, unrelated Cretans representing different Island parts have been studied for class II HLA-DRB1 and -DQB1 alleles. The most frequent ones w...
Source: Human Immunology - April 18, 2024 Category: Allergy & Immunology Authors: Antonio Arnaiz-Villena Ignacio Juarez Christian Vaquero-Yuste Tomas Lledo Jose Manuel Martin-Villa Fabio Suarez-Trujillo Source Type: research
Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research
The chemical composition of the aerial parts' essential oil of < em > Limonium lobatum < /em > (L.f.) Chaz. growing wild in Algeria
Nat Prod Res. 2024 Apr 16:1-8. doi: 10.1080/14786419.2024.2342001. Online ahead of print.ABSTRACTThe Limonium genus (Plumbaginaceae) includes several species of perennial herbs and shrubs belonging to a particular type of halophytes, known as 'recretohalophytes'. Limonium species are widely distributed in the Mediterranean region, mainly in the North-Eastern and Southern countries and several bioactivities have been well documented. In the present study, the chemical composition of the essential oil (EO) of the aerial parts of Limonium lobatum (L.f.) Chaz., a species never chemically previously studied and collected in Alg...
Source: Natural Product Research - April 16, 2024 Category: Biochemistry Authors: Larbi Derbak Natale Badalamenti Khellaf Rebbas Bendif Hamdi Maurizio Bruno Source Type: research
A sulfated exopolysaccharide derived from Chlorella sp. exhibiting in vitro anti- α-D-Glucosidase activity
This study aimed to isolate a polysaccharide-producing microalga from an extreme ecosystem and to evaluate its capacity to inhibit the α-D-glucosidase enzyme. Chlorella strain is isolated from hypersaline Lake in the Algerian desert. The exopolysaccharide extraction was performed by the concentration of free-cell supernatant in a rotary evaporator. The infrared analysis showed a characteristic footprint of carbohydrates with particular functional groups, such as sulfate. Gas chromatography-mass spectrometry has revealed a hetero-exopolysaccharide composed of galactose 35.75%, glucose 21.13%, xylose 16.81%, fructose 6.96%,...
Source: Archives of Microbiology - April 16, 2024 Category: Microbiology Authors: Karima Guehaz Zakaria Boual Alia Telli Hicham Meskher Hakim Belkhalfa Guillaume Pierre Philippe Michaud Alessandra Adessi Source Type: research
News at a glance: Jailed conservationists freed, physics titan dies, and diversity in anatomical illustrations
ASTRONOMY
Scientists flock to the eclipse
Tens of millions in North America turned their specially protected eyes to the skies on 8 April for several minutes of darkness when the Moon blocked the disk of the Sun, casting a shadow across Mexico, 15 U.S. states, and Canada. Researchers and citizen scientists seized the opportunity to study the corona—the wispy, outer layer of the Sun’s atmosphere—from the ground and in eclipse-chasing aircraft. They expected to see loops of plasma and other solar flares because the eclipse coincided with solar maximum, a period of high magnetic activity. Research...
Source: Science of Aging Knowledge Environment - April 11, 2024 Category: Geriatrics Source Type: research
Removal of malachite green from aqueous solution by kerolite/stevensite mixed-layer clay: full factorial design analysis
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Source: International Journal of Environmental Analytical Chemistry - April 11, 2024 Category: Chemistry Authors: Yassine BounouriMadjid BerkaniNabila HaddakMeriem IdireneSalima ZatoutSaloua TensaoutGhania FouraChafika MezitiSalima Harounea Facult é des Sciences Exactes, Laboratoire de Physico-chimie des Matériaux et Catalyse, Université de Bejaia, Bejaia, Algeria Source Type: research
The frequencies distribution of CYP3A5 rs776746 and ABCB1 rs1045642 polymorphisms in the west Algerian population and relationships with pharmacogenetics
Conclusion: The difference in the allelic and genotypic distribution of these polymorphisms emphasize the need for dose adjustmentsin drugs metabolized by CYP3A5 and transported by ABCB1 to optimize treatments outcomes.Keywords: CYP3A5; ABCB1; genetic polymorphism; pharmacogenetics; West Algeria. (Source: African Health Sciences)
Source: African Health Sciences - April 8, 2024 Category: African Health Authors: Amina Ammour, Meriem Aberkane, Abdallah Boudjema, Wefa Boughrara, Sounnia Mediene Benchekor Source Type: research
News at a glance: Giant telescope camera complete, limits to Paxlovid benefits, and missing battlefield bones
ASTRONOMY
Biggest ever digital camera heads to Chile
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Researchers at the SLAC National Accelerator Laboratory have finished building the biggest ever astronomical camera. It will create a movie of the universe, imaging the whole southern sky in unprecedented detail every 3 days.
Jacqueline Ramseyer Orrell/SLAC National Accelerator Laboratory
Researchers install the first of 21 arrays of image sensors that together make up the camer...
Source: Science of Aging Knowledge Environment - April 4, 2024 Category: Geriatrics Source Type: research
