[Impaired hypertension control in France: What the nephrologist needs to know].
Abstract In France, 1 adult out of 3 is affected by hypertension and only 1 hypertensive out of 4 achieves blood pressure targets (
Source: Nephrologie and Therapeutique - October 14, 2020 Category: Urology & Nephrology Authors: Rubin S, Boulestreau R, Couffinhal T, Combe C, Girerd X Tags: Nephrol Ther Source Type: research

[Intravascular large B cell lymphoma pathological findings led by positron emission tomography findings: About one case].
ich M Abstract Intravascular large B cell lymphoma is a rare non-Hodgkin large B cell lymphoma disease, with heterogeneous clinical manifestation and difficult pathological diagnosis. Positron emission tomography may be helpfull in this context and has already been reported. A 45-year-old woman was admitted for persistent high fever, inflammatory syndrome and unexplained haemophagocytic syndrome. Bilateral cortical renal hypermetabolism at positron emission tomography initially misled to pyelonephritis diagnosis and secondarily led to kidney biopsy, which showed intravascular large B cell lymphoma. Renal...
Source: Nephrologie and Therapeutique - July 31, 2020 Category: Urology & Nephrology Authors: Puigrenier S, Gnemmi V, Gibier JB, Dubois R, Collet G, Tricot S, Quémeneur T, Ulrich M Tags: Nephrol Ther Source Type: research

[Routine collection of perceived health data in the era of payment for quality: Recommendations by the Epidemiology and public health commission of the SFNDT].
The objective of this paper is to assess these indicators used in nephrology, markers in their own right of the quality of care. The patients reported outcomes measures considering the impact of illness or care and the Patient Reported Experience Measures considering their perception of their experience with the health care system or care pathway, are broader than quality of life. These PROs are measured using standardized and validated questionnaires, generic or specific. The Standardised Outcomes in Nephrology initiative has shown that PROs, too often neglected in favor of biological criteria, are instead favored by pati...
Source: Nephrologie and Therapeutique - July 31, 2020 Category: Urology & Nephrology Authors: Ayav C, Couchoud C, Sautenet B, Lobbedez T, Sens F, Moranne O, Commission épidémiologie et santé publique de la Société francophone de néphrologie, dialyse et transplantation Tags: Nephrol Ther Source Type: research

[ANCA-vasculitis with renal impairment treated by intravenous versus oral cyclophosphamide: Multicentric analysis of relapse free survival (VaReCyS)].
Abstract INTRODUCTION: ANCA-vasculitis are associated with high morbidity and mortality. Large use of cyclophosphamide as induction immunosuppressive therapy is limited by its side effects. All recent literature trends in decreasing cumulative dose while optimizing maintenance therapy. METHODS: This retrospective multicentric analysis included ANCA-vasculitis patients with renal impairment and de novo diagnose followed in Rennes and Vannes hospitals for 2 years minimum. The primary endpoint was to analyze relapse free survival comparing oral and intravenous administration of cyclophosphamide. RESULT...
Source: Nephrologie and Therapeutique - July 7, 2020 Category: Urology & Nephrology Authors: Gouin JB, Dhalluin T, Perrichot R, Vigneau C, Michel A Tags: Nephrol Ther Source Type: research

[Hypokalemia with pseudo-hyperaldosteronism: Is it Lidl ® syndrome?]
DISCUSSION: The consumption of glycyrrhizin is a well-known aetiology for pseudo-hyperaldosteronism. It is commonly mentioned amongst excessive consumers of liquorice or of non-alcoholic anise drinks. Drinks that are derived from original pastis contain varying levels of glycyrrhizin, which is used as a flavour enhancer and can become toxic in cases of prolonged and important consumption. PMID: 32631747 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - July 2, 2020 Category: Urology & Nephrology Authors: Eustache G, Michel A, Golbin L, Vigneau C Tags: Nephrol Ther Source Type: research

[Bartter-Gitelman syndromes].
Abstract Bartter-Gitelman syndromes are rare inherited autosomal recessive salt-losing tubulopathies characterized by severe and chronic hypokalemia associated with metabolic alkalosis and secondary hyperaldosteronism. Bartter syndrome results from a furosemide-like defect in sodium reabsorption in the Henle's loop leading to hypercalciuria and defect in urinary concentration capacity. The antenatal Bartter syndrome is defined by polyhydramnios and an infantile polyuria with severe dehydration whereas classic Bartter syndrome appears during childhood or adulthood. Gitelman syndrome is a thiazide-like salt-losing t...
Source: Nephrologie and Therapeutique - June 30, 2020 Category: Urology & Nephrology Authors: Blanchard A, Courand PY, Livrozet M, Vargas-Poussou R Tags: Nephrol Ther Source Type: research

[Advance directives in hemodialysis patient: A feasibility study].
lé B Abstract Respect of patient's autonomy is essential. So that patients are able to write their advance directives in case of a situation where they are unable to make decisions for themselves. Currently, few people have written advance directives. We studied the feasibility of a systematic implementation of advance directives in haemodialysis patients. This prospective, single-center study was conducted in an ambulatory hemodialysis center. There were 4 steps: caregivers survey about advance directives; selection of patients and information about advance directives; writing advance directives with the i...
Source: Nephrologie and Therapeutique - June 26, 2020 Category: Urology & Nephrology Authors: D'Halluin P, Sautenet B, François M, Birmelé B Tags: Nephrol Ther Source Type: research

Reprint of: Kidney health for everyone everywhere-from prevention to detection and equitable access to care.
PMID: 32600861 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - June 25, 2020 Category: Urology & Nephrology Authors: Li PK, Garcia-Garcia G, Lui SF, Andreoli S, Fung WW, Hradsky A, Kumaraswami L, Liakopoulos V, Rakhimova Z, Saadi G, Strani L, Ulasi I, Kalantar-Zadeh K, World Kidney Day Steering Committee Tags: Nephrol Ther Source Type: research

[Carfilzomib-induced haemolytic and uremic syndrome: Favorable outcome with eculizumab].
We report the case of a patient who developed "secondary" hemolytic and uremic syndrome associated with carfilzomib, a proteasome inhibitor which is used in case of multiple myeloma relapses. Besides stopping the treatment, the patient still showed signs of hemolysis and renal failure with anuria requiring hemodialysis. An eculizumab treatment was therefore initiated. The overall evolution was favorable and an improvement of the renal function promptly allowed the discontinuation of hemodialysis. We discuss the mechanisms that may activate the alternative complement pathway and the potential interest of a transie...
Source: Nephrologie and Therapeutique - June 18, 2020 Category: Urology & Nephrology Authors: Casiez C, Pica GM, Bally S Tags: Nephrol Ther Source Type: research

[Capnocytophaga spp. peritonitis in a peritoneal dialysis: A case report].
CONCLUSION: The case of our patient once again reveals the diagnostic difficulties posed by Capnocytophaga spp. Innovative techniques, such as MALDI-TOF-MS or genomic sequencing of ribosomal RNA, should be further used in peritoneal dialysis in the diagnosis of peritonitis. PMID: 32571739 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - June 18, 2020 Category: Urology & Nephrology Authors: Noto Kadou Kaza B, Nogier MB, Tosi PO, Floch P Tags: Nephrol Ther Source Type: research

[Ischemia-reperfusion injury after kidney transplantation].
Abstract Ischemia-reperfusion injury is an inescapable phenomenon in kidney transplantation. It combines lesional processes of biochemical origin associated with oxydative stress and of immunological origin in connection with the recruitment and activation of innate immunity cells. Histological lesions associate acute tubular necrosis and interstitial œdema, which can progress to interstitial fibrosis. The extent of these lesions depends on donor characteristics (age, expanded criteria donor, etc.) and cold ischemia time. In the short term, ischemia-reperfusion results in delayed recovery of graft function. ...
Source: Nephrologie and Therapeutique - June 18, 2020 Category: Urology & Nephrology Authors: Dufour L, Ferhat M, Robin A, Inal S, Favreau F, Goujon JM, Hauet T, Gombert JM, Herbelin A, Thierry A Tags: Nephrol Ther Source Type: research

The effect of self-care education through teach back method on the quality of life in hemodialysis patients.
CONCLUSION: This study showed that self-care education through teach back method improves the quality of life in hemodialysis patients. Therefore, it is recommended that nurses in the hemodialysis unit implement self-care education through teach back method as an important task. PMID: 32532600 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - June 8, 2020 Category: Urology & Nephrology Authors: Abbasi Abianeh N, Abdollah Zargar S, Amirkhani A, Adelipouramlash A Tags: Nephrol Ther Source Type: research

[Use of iron in nephrology: Results of a French practical survey].
zot C Abstract The French-speaking Society of Nephrology, Dialysis and Transplantation conducted, in 2018, a survey among French nephrologists into their iron prescribing habits for patients with chronic kidney disease stages 3 to 5 before dialysis. The results show that 73% of nephrologists use intravenous iron before dialysis stage. When a patient has gastrointestinal symptoms under oral iron therapy, only 48% of nephrologists use intravenous route. The starting thresholds for iron are for 78% of nephrologists a transferrin saturation
Source: Nephrologie and Therapeutique - May 10, 2020 Category: Urology & Nephrology Authors: Brunet P, Choukroun G, Moulin B, Zaoui P, Thervet É, Frimat L, Chazot C Tags: Nephrol Ther Source Type: research

[Who are these patients on dialysis and not on the kidney transplant waiting list?]
net C Abstract Access to kidney transplants for patients with end-stage chronic renal disease is a major challenge in France. Registration on the transplant waiting list is a mandatory step to be able to access this technique. The Haute Autorité de santé (HAS) updated, in 2015, the contraindications to access this list. In this context, we wanted to make an inventory of the reasons for non-registration on the renal transplant waiting list in patients on dialysis for at least a year, aged less than 80 years, in France. All patients included in the Epidemiology and Nephrology Information Register ...
Source: Nephrologie and Therapeutique - May 10, 2020 Category: Urology & Nephrology Authors: Vabret E, Vigneau C, Bayat S, Frimat L, Monnet É, Hannedouche T, Jacquelinet C Tags: Nephrol Ther Source Type: research

[What do we know about these dialysed patients who are not on the waiting list?]
PMID: 32409291 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - May 10, 2020 Category: Urology & Nephrology Authors: Hourmant M, Chatelet V Tags: Nephrol Ther Source Type: research

[Natriuretic peptides in  dialysis: From theory to clinical practice].
[Natriuretic peptides in dialysis: From theory to clinical practice]. Nephrol Ther. 2020 May 11;: Authors: Jean G, Deleaval P, Chazot C Abstract Cardiologists and emergency-wards physicians are used to check natriuretic peptides serum level, mainly B-type natriuretic peptide and N-terminal pro-Brain natriuretic peptide for acute cardiac failure diagnosis. Due to their accumulation in chronic kidney disease and their elimination by dialysis, natriuretic peptides sampling remains debatable in chronic kidney disease patients. In dialysis patients, high natriuretic peptides values are associated...
Source: Nephrologie and Therapeutique - May 10, 2020 Category: Urology & Nephrology Authors: Jean G, Deleaval P, Chazot C Tags: Nephrol Ther Source Type: research

Undiagnosed chronic kidney disease and  its associated risk factors in an agricultural Moroccan adult's population.
This study aimed to estimate the prevalence of chronic kidney disease and its associated risk factors among Moroccan population sample from Sidi Bennour province. METHODS: An observational, descriptive and analytical study was conducted in an agricultural community of Morocco. A sample of 182 subjects aged 18 or older, randomly selected from the province health care centers. The information on the participants was collected using a structured questionnaire, blood samples were collected and the serum creatinine was determined. Subsequent glomerular filtration rate (eGFR) was estimated by the modification of d...
Source: Nephrologie and Therapeutique - April 7, 2020 Category: Urology & Nephrology Authors: Moustakim R, El Ayachi M, Mziwira M, Belahsen R Tags: Nephrol Ther Source Type: research

Comparison between citrate and acetate dialysate in  chronic online hemodiafiltration: A short-term prospective study in pediatric settings.
CONCLUSION: The use of citrate instead of acetate in dialysis and substitution solutions appears in the short term as a safe alternative for chronic online hemodiafiltration in children. PMID: 32278736 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - April 7, 2020 Category: Urology & Nephrology Authors: Quinaux T, Pongas M, Guissard É, Ait-Djafer Z, Camoin-Schweitzer MC, Ranchin B, Vrillon I Tags: Nephrol Ther Source Type: research

[Vaccine recommendations for children with idiopathic nephrotic syndrome].
lier S, Vrillon I Abstract The specific treatment of idiopathic nephrotic syndrome is based on corticosteroid therapy and/or steroid-sparing immunosuppressive agents in children who are steroid-dependant or frequent relapsers (60-70 %). Patients have an increased infectious risk not only related to the disease during relapses (hypogammaglobulinemia and urinary leakage of opsonins) but also to treatments (corticosteroids or immunosuppressive agents) in period of remission. Vaccination is therefore particularly recommended in these patients. Potential vaccine risks are ineffectiveness, induction of vaccine dise...
Source: Nephrologie and Therapeutique - April 7, 2020 Category: Urology & Nephrology Authors: Boyer O, Baudouin V, Bérard É, Biebuyck-Gougé N, Dossier C, Guigonis V, Audard V, Klifa R, Leroy V, Ranchin B, Roussey G, Samaille C, Tellier S, Vrillon I Tags: Nephrol Ther Source Type: research

[Poisson regression use in nephrology].
rologie, dialyse et transplantation Abstract Poisson regression is a powerful tool for the analysis of incidence rates from cohort survival studies and facilitates simple, straightforward analyses of temporal patterns that may be difficult to assess with other methods. The Kaplan-Meier method, the logrank test, and the Cox model each have their respective parallels in grouped data analysis: instantaneous hazards, the hazard ratio for grouped data, and Poisson regression, grouped by intervals. This approach makes it possible to present the instantaneous speed of occurrence of events that may be more significant for...
Source: Nephrologie and Therapeutique - April 6, 2020 Category: Urology & Nephrology Authors: Couchoud C, Commission épidémiologie et santé publique de la Société francophone de néphrologie, dialyse et transplantation Tags: Nephrol Ther Source Type: research

[Analysis of the infectious risk around the patient in the hemodialysis unit of Ibn Sina Rabat hospital using the failure modes, effects and criticality analysis method].
CONCLUSION: This analysis makes it possible, through periodic evaluations, to enter a real quality approach, which reinforces the satisfaction of the patients as well as all the actors of the hemodialysis center. PMID: 32192869 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - March 15, 2020 Category: Urology & Nephrology Authors: El Marnissi S, Khomsi Z, Kassy Raymond Sylvestre A, El Harti J, Taoufik J, Chaibi A, Benamar L, Bayahia R Tags: Nephrol Ther Source Type: research

[Nephrolithiasis: From mechanisms to preventive medical treatment].
Abstract Renal lithiasis is a frequent pathology (prevalence ranging from 10 to 12% in France) and a recurrent condition. It is associated with chronic kidney disease and is responsible for 2 to 3% of cases of end-stage renal disease, especially if it is associated with nephrocalcinosis and/or is part of a monogenic disease (1.6% of lithiasis in adults, including 1% of cystinuria). In order to understand the pathophysiology of the nephrolithiasis, the analysis of stones (morphological and by infrared spectrophotometry) as well as a minimal biological evaluation including crystalluria must be carried out. Calcium n...
Source: Nephrologie and Therapeutique - February 27, 2020 Category: Urology & Nephrology Authors: Courbebaisse M, Prot-Bertoye C, Daudon M Tags: Nephrol Ther Source Type: research

[How to manage abdominal hernia on peritoneal dialysis?]
bet M Abstract Abdominal hernias are a frequent complication in peritoneal dialysis, representing up to 60.4% of anatomical complications. Their prevalence varies between 7 and 27.5%. Established risk factors are male gender, an older age, multiparity, a low body mass index and a paramedian approach for the catheter insertion. Polykystic renal disease and the intra-peritoneal volume are controversial risk factors. The diagnosis is mainly clinical, though peritoneography imaging can be useful in difficult cases. Hernia's complications, of strangulation, incarceration, bowel occlusion and peritonitis; can be very se...
Source: Nephrologie and Therapeutique - January 26, 2020 Category: Urology & Nephrology Authors: Boyer A, Bonnamy C, Lanot A, Guillouet S, Béchade C, Recorbet M Tags: Nephrol Ther Source Type: research

[Clarification of the method used for drug dosage adjustment in patients with renal failure: The CLEAR study].
CONCLUSION: The majority of summaries of product characteristics do not mention the Cockcroft-Gault formula and in the majority of cases it is not possible to identify the formula or technique used in the studies on which is based the reference to dosage adjustment in the summarie of product characteristics. In addition, there are discrepancies between the wording of the summaries of product characteristics and the data from development studies. The use of Cockcroft-Gault for dosage adjustment is to be questioned, especially since the Isotope-dilution mass spectrometry, or IDMS, standardization of creatinine dosage makes o...
Source: Nephrologie and Therapeutique - January 23, 2020 Category: Urology & Nephrology Authors: Berdougo J, Delorière É, Deray G, Launay-Vacher V Tags: Nephrol Ther Source Type: research

[End stage kidney disease in Maghreb and Africa: Overview of transplant programs in Maghreb and Africa].
sig M Abstract Kidney transplantation is the best treatment for the patient with end stage kidney disease in term of increasing the survival rate, reducing complications, improving quality of live and its lower cost compared to peritoneal dialysis or hemodialysis. However, the number of patients waiting for kidney transplantation is growing day by day and the gap between demand and supply is still huge. This situation is even more complicated in developing countries where the lack of legislation, infrastructure and government involvement is common. Some national transplantation programs have been implemented, with...
Source: Nephrologie and Therapeutique - January 23, 2020 Category: Urology & Nephrology Authors: Nlandu Y, Hamaz S, Robert A, Cheddani L, Vilaine È, Seidowsky A, Ebel A, Massy Z, Essig M Tags: Nephrol Ther Source Type: research

[Low Body Mass Index and impact of antiretroviral therapy on nephrotoxicity, chronic renal disease among HIV-infected patients in Brazzaville, Congo].
Abstract OBJECTIVE: To describe the incidence and risks factors of ART induced nephrotoxicity and chronic kidney disease in HIV-1-infected adults with low body mass index (
Source: Nephrologie and Therapeutique - January 23, 2020 Category: Urology & Nephrology Authors: Herbas Ekat M, Tidiane Ndour C, Bienvenue Ossibi Ibara R, Diafouka M, Boumandoki P, Adoua Doukaga T, Axel Aloumba G, Mahambou-Nsonde D, Roger Nzounza P, Obengui P, Seydi M Tags: Nephrol Ther Source Type: research

[Amending of the 3rd cycle of medical studies in France: What the nephrologists stand for].
io JP Abstract 2017 was the year during which France has seen the amendment of the 3rd cycle of medical education. Three new steps have been uploaded: "basement", "in depth", and "liability". The latter has been particularly discussed as it is really close to the former post-graduate state. Nephrology has always been a very attractive discipline. While most others have been increased in terms of length in initial medical education, nephrology has been assigned to 4 years. Altogether, nephrologists whatever their generation have led a series of questionnaires we report here. From 3 of ...
Source: Nephrologie and Therapeutique - January 16, 2020 Category: Urology & Nephrology Authors: Lohéac C, Maisons V, Bureau C, Bertocchio JP Tags: Nephrol Ther Source Type: research

[Ericksonian hypnosis and mindfulness meditation: Towards a behavioral medicine in nephrology].
The objective of this report is to describe how Ericksonian hypnosis, mindfulness meditation and compassion meditation could support chronic kidney disease patients, their caregivers and the health-care professional. PMID: 31928954 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - January 8, 2020 Category: Urology & Nephrology Authors: Thuillier Lecouf A, Videloup L, Letrecher S, Béchade C, Recorbet M, Chatelet V Tags: Nephrol Ther Source Type: research

[Nephropathy associated with hypocomplementemic urticarial vasculitis: A case report and literature review].
Abstract Hypocomplementemic urticarial vasculitis is a rare systemic vasculitis, affecting small vessels, characterised by chronicle urticaria, hypocomplementemia, and systemic manifestations. Renal involvement, whose prevalence varies between 9% and 60%, is mainly glomerular. We here report the case of a 59 years old woman presenting kidney failure, associated with chronicle urticaria and arthralgias. Laboratory investigation showed haematuria, proteinuria, hypocomplementemia and anti-SSa antibody positivity. A percutaneous kidney biopsy revealed focal and segmental glomerulonephritis associated with an acute int...
Source: Nephrologie and Therapeutique - January 8, 2020 Category: Urology & Nephrology Authors: Boyer A, Gautier N, Comoz F, Hurault de Ligny B, Aouba A, Lanot A Tags: Nephrol Ther Source Type: research

[Premature immune senescence and chronic kidney disease: Update and perspectives].
In conclusion, to reduce the increasing incidence of morbidity and mortality of chronic kidney disease patients, a better knowledge of uremia-induced immune senescence would help to pave the way to build clinical studies and promote innovative therapeutic approaches. We believe that therapeutic reversion and immune senescence prevention approaches will be part of the management of chronic kidney disease patients in the future. PMID: 31848067 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 13, 2019 Category: Urology & Nephrology Authors: Crépin T, Legendre M, Courivaud C, Vauchy C, Laheurte C, Rebibou JM, Saas P, Ducloux D, Bamoulid J Tags: Nephrol Ther Source Type: research

[Immune check point inhibitor-associated renal toxicity].
Abstract Immune checkpoint inhibition had a major clinical success in clinical oncology and impacted the treatment paradigm in many cancers. Immune related adverse events are well-described toxicities that are closely associated with CPI therapies and can involve any organ in the body. Renal toxicity is multifocal. In addition to the predominant tubulointerstitial involvement, immunotherapy can lead to a variety of glomerular damage and electrolyte disorders. Suggested mechanisms include direct renal interstitium lymphocyte infiltration, renal immune complex deposition, microangiopathic endothelial disease, or cyt...
Source: Nephrologie and Therapeutique - December 12, 2019 Category: Urology & Nephrology Authors: Izzedine H, Gueutin V Tags: Nephrol Ther Source Type: research

[Potential application of fibroblast growth factor 23-klotho axis in chronic kidney disease].
Abstract Membrane Alpha Klotho (α-klotho) is expressed in the kidney and functions as a co-receptor of FGF receptors (FGFRs) to activate specific fibroblast growth factor 23 (FGF23) signal pathway. FGF23 is produced in bones and participates in mineral homeostasis. The extracellular domain of transmembrane αklotho can be cleaved by proteases and released into the circulation as soluble α-klotho. Klotho deficiency is a pathogenic factor for chronic kidney disease progression and cardiovascular diseases. The FGF23 excess may also contribute to cardiovascular diseases where its pathogenic effect act...
Source: Nephrologie and Therapeutique - December 12, 2019 Category: Urology & Nephrology Authors: Lacroix JS, Urena-Torres P Tags: Nephrol Ther Source Type: research

[Renal toxicities of targeted therapies in oncology].
This article reviews the renal toxicity associated with targeted anticancer therapies directed against Epidermal growth factor receptor, Human epidermal growth factor-2, B-rapidly accelerated fibrosarcoma, Mitogen-activated protein kinase, Anaplastic lymphoma kinase, Programmed cell death-1/programmed cell death ligand-1, Cytotoxic T lymphocyte antigen-4 and Vascular endothelial growth factor/receptor. The early diagnosis and management of these renal adverse events is essential for the clinician who cares for such patients. PMID: 31818703 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 5, 2019 Category: Urology & Nephrology Authors: Izzedine H Tags: Nephrol Ther Source Type: research

[Erratum to "A better characterization of kidney allograft rejection infiltrates using in situ multiplex immunofluorescence" [Nephrol. Ther. 15S (2019) S43-S52]].
[Erratum to "A better characterization of kidney allograft rejection infiltrates using in situ multiplex immunofluorescence" [Nephrol. Ther. 15S (2019) S43-S52]]. Nephrol Ther. 2019 Dec;15(7):553 Authors: Calvani J, Terada M, Lesaffre C, Duong Van Huyen JP, Bruneval P, Rabant M PMID: 31787168 [PubMed - in process] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - November 30, 2019 Category: Urology & Nephrology Authors: Calvani J, Terada M, Lesaffre C, Duong Van Huyen JP, Bruneval P, Rabant M Tags: Nephrol Ther Source Type: research

Evolution of secondary hyperparathyroidism in patients following return to hemodialysis after kidney transplant failure.
Abstract INTRODUCTION: Severe uncontrolled secondary hyperparathyroidism and kidney transplantation history are both risk factors for fractures in hemodialyzed patients. Moreover, patients who return to dialysis after transplant failure have more severe infections/anemia and higher mortality risk than transplant-naive patients starting dialysis with native kidneys. In this context, our aim was to test the hypothesis that transplant failure patients have more secondary hyperparathyroidism than transplant-naive patients. METHODS: We retrospectively compared 29 transplant failure patients to 58 transpl...
Source: Nephrologie and Therapeutique - November 28, 2019 Category: Urology & Nephrology Authors: Jannot M, Normand M, Chabroux-Seffert A, Azzouz L, Afiani A, Jurine J, Ziane A, Mariat C, Lafage-Proust MH Tags: Nephrol Ther Source Type: research

[Sodium metabolism: An update in 2019].
Abstract The classical theory of sodium metabolism considers mostly its role on the extracellular volume according to a daily response to the variations of salt intake, correlated to the variations of water volume. Recent works consider sodium tissular storage. This non-osmotic pool could play a role in blood pressure regulation and in immunity mechanisms. The regulation modalities could be more complex, organised over the long term, with a modification of the sodium-water relationship. The aim of this article is to give a new insight on sodium metabolism, based on recent works, especially on the role and regulati...
Source: Nephrologie and Therapeutique - November 28, 2019 Category: Urology & Nephrology Authors: Robert A, Cheddani L, Ebel A, Vilaine E, Seidowsky A, Massy Z, Essig M Tags: Nephrol Ther Source Type: research

[The contribution of an ethical concertation group in nephrology validated by a research protocol].
ing L Abstract For more than 10 years, nephrologists in the Grenoble-region have sought advice from the Ethical Concertation Unit in Nephrology with regards to whether to stop or continue dialysis for patients under palliative care. This process deserves a multidisciplinary debate between health professionals and qualified non-health professionals. Thus, we organized a qualitative research protocol in three parts (medical, philosophical, judicial) to explore this issue. Our study aimed to assess the impact of Ethical Concertation Unit in Nephrology's discussions regarding perception, knowledge, and judicial and et...
Source: Nephrologie and Therapeutique - November 10, 2019 Category: Urology & Nephrology Authors: Maurizi-Balzan J, Fourneret É, Cimar L, Noble J, Naciri-Bennani H, Tetaz R, Rostaing L Tags: Nephrol Ther Source Type: research

[Criteria to indicate kidney biopsy in type 2 diabetic patients with proteinuria: Survey among French nephrologists].
sik F Abstract Diabetic nephropathy is usually a presumptive diagnosis based on clinical and biological evidence. Renal biopsies are performed in diabetic patients with atypical findings evoking non-diabetic renal disease who could benefit from specific therapies. French speaking nephrologists were asked which criteria they retain to indicate renal biopsy in patients with type 2 diabetes and albuminuria>0.5g/day or equivalent through an online anonymous questionnaire. Among the suggested criteria were absence of diabetic retinopathy, hematuria, rapid decrease in GFR, short diabetes duration or rapid raise ...
Source: Nephrologie and Therapeutique - November 8, 2019 Category: Urology & Nephrology Authors: Chemouny JM, Sannier A, Hanouna G, Raimbourg Q, Daugas É, Vigneau C, Vrtovnsik F Tags: Nephrol Ther Source Type: research

[Descriptive study of practices with patients in conservative care practices in a French district, the Normandy].
CONCLUSION: The results of this study show that the course of the patients in conservative treatment is heterogeneous and is not formalized. Improvements are needed to integrate conservative treatment for patients with chronic kidney disease. PMID: 31718994 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - November 8, 2019 Category: Urology & Nephrology Authors: Uteza S, Thuillier Lecouf A, Videloup L, Béchade C, Henri P, Guillouët S Tags: Nephrol Ther Source Type: research

[Kidney disease care for the elderly].
This article aims to focus on the kidney diseases commonly observed in elderly patients and analyze their specific nephrogeriatric care modalities. It should be noticed that all known kidney diseases can be also observed in the elderly, most often with a quite similar clinical presentation. This review is thus focused on the diseases most frequently and most specifically observed in elderly patients (except for monoclonal gammopathy associated nephropathies, out of the scope of this work), as well as the peculiarities of old age nephrological care. PMID: 31711751 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - November 7, 2019 Category: Urology & Nephrology Authors: Hamroun A, Frimat M, Beuscart JB, Buob D, Lionet A, Lebas C, Daroux M, Provôt F, Hazzan M, Boulanger É, Glowacki F Tags: Nephrol Ther Source Type: research

[Anxiety and depression during chronic renal failure before end stage at the University hospital center Yalgado Ouedraogo of Ouagadougou (Burkina Faso)].
ogo A Abstract AIM: We wanted to know the prevalence of depression and anxiety, as well as the associated factors in patients with chronic renal failure in Burkina Faso. PATIENTS AND METHODS: This was an analytical cross-sectional study conducted from February to May 2016. We included all adult patients with moderate or severe chronic renal failure. The diagnosis of anxiety and depression was made using the Hamilton scales. Identification of factors associated with both conditions required bi- and multivariate analyzes. RESULTS: The study involved 191 patients, with a mean age of 53.2±14.2&nb...
Source: Nephrologie and Therapeutique - November 2, 2019 Category: Urology & Nephrology Authors: Coulibaly G, Goumbri PP, Lengani HYA, Millogo T, Zoma VP, Dabilgou A, Napon C, Karfo K, Ouango GJ, Lengani A, Ouédraogo A Tags: Nephrol Ther Source Type: research

[Hygieno-dietetic recommendations in the prevention of accumulation of advanced glycation products].
Abstract Advanced glycation products are proteins whose structural and functional properties have been modified by a process of oxidative glycation. The accumulation of advanced glycation products in most tissues and the oxidative stress and inflammatory reactions that accompany it, account for the multi-systemic impairment observed particularly in the elderly, diabetics and in chronic renal failure. The advanced glycation products endogenous production is continuous, related to oxidative stress, but the most important source of advanced glycation products is exogenous, mainly of food origin. Exogenous advanced gl...
Source: Nephrologie and Therapeutique - October 30, 2019 Category: Urology & Nephrology Authors: Chauveau P, Lasseur C, Azar R, Niu W, Combe C, Aparicio M Tags: Nephrol Ther Source Type: research

[Epidemiology of acute renal failure during dengue fever in the city of Ouagadougou].
CONCLUSION: The acute renal failure in our dengue fever patients population was very common, severe, and highly lethal. The prognosis should improve with early management. It would be even better to promote primary prevention through effective vector control. PMID: 31669117 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - October 24, 2019 Category: Urology & Nephrology Authors: Coulibaly G, Lengani HYA, Sondo KA, Konvolbo HP, Diendéré ÉA, Nitiéma IJ, Karambiri AR, Sanou G, Lengani A Tags: Nephrol Ther Source Type: research

Reasons for dialysis patients choosing or refusing kidney transplantation as renal replacement therapy: A qualitative study.
Abstract This paper aims to identify the reasons for choosing or refusing kidney transplantation as renal replacement therapy among patients with Chronic Kidney Disease (CKD). Data were collected through interviews with CKD patients treated by dialysis. Health professionals were also interviewed. A thematic analysis was used to analyze the data. Results show that various reasons account for CKD patients' refusal to have a kidney transplant: the perception of kidney transplantation as a renal replacement therapy without positive outcome, refusal to have an allograft. There are also situations such as the lack of or...
Source: Nephrologie and Therapeutique - October 22, 2019 Category: Urology & Nephrology Authors: Senghor AS Tags: Nephrol Ther Source Type: research

[Renal transplantation: Procedure and early follow-up].
ute; D, Méjean A, Legendre C Abstract More than fifty years after the success of the two first renal transplantations in Boston and in Necker hospital in Paris, renal transplantation became the treatment of choice of end stage renal failure, because it improves not only the quality of life of the patients but also their long-term survival. In France, more than 3,700 kidney transplantations are performed every year and more than 40,000 patients are living with a functioning kidney allograft. This treatment of end stage renal disease requires a fine-tuned pre-transplant evaluation and a multidi...
Source: Nephrologie and Therapeutique - October 18, 2019 Category: Urology & Nephrology Authors: Anglicheau D, Tinel C, Canaud G, Loupy A, Zuber J, Delville M, Rabaté C, Scemla A, Snanoudj R, Sberro-Soussan R, Mamzer-Bruneel MF, Bererhi L, Martinez F, Timsit MO, Rabant M, Correas JM, Bienaimé F, Duong JP, Hélénon O, Prié D, Méjean A, Legendre C Tags: Nephrol Ther Source Type: research

[e-Health in nephrology: 1st French survey on telenephrology].
In conclusion, French nephrologists are yet connected but they really need more help again to face new challenges raised by e-health. PMID: 31640944 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - October 18, 2019 Category: Urology & Nephrology Authors: Citarda S, Camarroque AL, Seret G, De Laforcade L, Bureau C, Caillette-Beaudoin A, Bertocchio JP, Comité scientifique du club des jeunes néphrologues Tags: Nephrol Ther Source Type: research

[Risk analysis and validation of the process for producing the substitution fluid for online hemodiafiltration].
CONCLUSION: This work has enabled us to validate our production process in extreme cases to promote safer use of the technique. PMID: 31636047 [PubMed - as supplied by publisher] (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - October 17, 2019 Category: Urology & Nephrology Authors: Yousfi MA, Ben Saada R, Ourir A, Bafoun A, Jalel Hmida M Tags: Nephrol Ther Source Type: research

[A patient with rheumatoid arthritis presenting a nephrotic syndrome: A case report].
Abstract A fifty-one years-old patient with a history of rheumatoid arthritis of recent diagnosis is hospitalized for exploration of a rapidly progressive anasarca state. First analysis discovered an impure nephrotic syndrome (acute renal failure, hematuria) and massive glomerular proteinuria. Auto-medication by nonsteroidal anti-inflammatory drug was revealed. Renal biopsy showed minimal glomerular disease and acute tubular necrosis. Corticosteroid use permitted a normalization of proteinuria and renal recovery was obtained. Literature review showed renal impairment occurring in rheumatoid polyarthritis. Minimal ...
Source: Nephrologie and Therapeutique - October 17, 2019 Category: Urology & Nephrology Authors: Daniel A, Gibier JB, Azar R Tags: Nephrol Ther Source Type: research

[Prevention of iatrogenic risk and screening of chronic kidney disease].
Abstract Ten percent of the world's population is affected by chronic kidney disease that can lead to kidney failure. In France, nearly three million people are concerned, half of whom are undiagnosed, 85,000 people are on dialysis or waiting for a kidney transplant. Each year, 11,000 new diagnoses of severe renal failure are made, one third of which had not been treated before. Kidney failure is constantly increasing due to the aging of the population and the resurgence of chronic diseases, including obesity and cardiovascular diseases such as high blood pressure and diabetes, two conditions that impair...
Source: Nephrologie and Therapeutique - October 17, 2019 Category: Urology & Nephrology Authors: Vasmant D Tags: Nephrol Ther Source Type: research

Complement inhibition in ANCA vasculitis.
Abstract A role for the alternative complement pathway has emerged in the understanding of ANCA vasculitis pathogenesis. Current therapies of ANCA vasculitis are limited by partial efficacy and toxicity and many patients pursue a relapsing course. Improved therapies are needed. Inhibition of the alternative complement pathway component C5a is attractive due to its role in neutrophil activation and migration, and engagement of other inflammatory and thrombotic mechanisms. Two inhibitors of C5a are in clinical development for ANCA vasculitis: avacopan, an oral C5a receptor inhibitor has demonstrated efficacy, safety...
Source: Nephrologie and Therapeutique - October 16, 2019 Category: Urology & Nephrology Authors: Jayne D Tags: Nephrol Ther Source Type: research