MALDI-TOF mass spectrometry identification and antifungal susceptibility testing of yeasts causing vulvovaginal candidiasis (VVC) in Tebessa (Northeastern Algeria)
Ann Biol Clin (Paris). 2024 Jan 1;81(6). doi: 10.1684/abc.2023.1852. Online ahead of print.ABSTRACTVulvovaginal candidiasis (VVC) alongside with antifungal resistance are becoming a major clinical problem in recent years. A prospective study aimed to evaluate the diversity of yeast strains associated with VVC in Tebessa city (northeastern Algeria) and investigate their susceptibility patterns. Over two months, yeasts were isolated on chromogenic medium from twenty-nine non-pregnant women with symptomatic VVC. The isolates were characterized with MALDI-TOF MS and antifungal susceptibility testing was performed for nine anti...
Source: Annales de Biologie Clinique - January 8, 2024 Category: Biochemistry Authors: Mabrouka Benhadj Taha Menasria St éphane Ranque Source Type: research
MALDI-TOF mass spectrometry identification and antifungal susceptibility testing of yeasts causing vulvovaginal candidiasis (VVC) in Tebessa (Northeastern Algeria)
Ann Biol Clin (Paris). 2024 Jan 1;81(6). doi: 10.1684/abc.2023.1852. Online ahead of print.ABSTRACTVulvovaginal candidiasis (VVC) alongside with antifungal resistance are becoming a major clinical problem in recent years. A prospective study aimed to evaluate the diversity of yeast strains associated with VVC in Tebessa city (northeastern Algeria) and investigate their susceptibility patterns. Over two months, yeasts were isolated on chromogenic medium from twenty-nine non-pregnant women with symptomatic VVC. The isolates were characterized with MALDI-TOF MS and antifungal susceptibility testing was performed for nine anti...
Source: Annales de Biologie Clinique - January 8, 2024 Category: Biochemistry Authors: Mabrouka Benhadj Taha Menasria St éphane Ranque Source Type: research
GSE233619 Fungicide-tolerant persister formation during cryptococcal pulmonary infection
Contributors : Weixin Ke ; Yingying Chen ; Yuyan Xie ; Linqi WangSeries Type : Expression profiling by high throughput sequencingOrganism : Cryptococcus neoformans var. grubii H99Bacterial persisters, a subpopulation of genetically susceptible cells that are normally dormant and tolerant to bactericides, have been studied extensively because of their clinical importance. In comparison, much less is known about the determinants underlying fungicide-tolerant fungal persister formation in vivo. Here, we report that during mouse lung infection, Cryptococcus neoformans forms persisters that are highly tolerant to amphoteric...
Source: GEO: Gene Expression Omnibus - January 8, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Cryptococcus neoformans var. grubii H99 Source Type: research
Minimizing the Recurrence Rate in Covid Associated Mucormycosis: Our Experience in 500 Patients
AbstractMucormycosis is an aggressive, fatal fungal infection. The fungal organisms are ubiquitous and easily affect immunocompromised patients. The main aim of this article is to emphasize over the knowledge of different diagnostic methods (diagnostic nasal endoscopy, ct/ contrast mri pns + orbit + brain, Wet KOH mount), the importance of practising an aggressive surgical resection, medical treatments (liposomal amphotericin B, amphotericin gel, tablet posaconazole, nasal douching, retrorbital amphotericin injection), suction cleaning and regular follow up of the patient aft er surgical management. This can great...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 7, 2024 Category: ENT & OMF Source Type: research
Role of Amphotericin B in the Treatment of Mucormycosis
CONCLUSION: The article demonstrates the traits of the drug associated with its chemical, pharmacokinetics, stability, and other features, and illustrates their most useful characteristics for clinical application.PMID:38178658 | DOI:10.2174/0113816128272443231221101415 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 5, 2024 Category: Drugs & Pharmacology Authors: Alisha Sachdeva Monika Targhotra Meenakshi Kanwar Chauhan Monica Chopra Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
Role of Amphotericin B in the Treatment of Mucormycosis
CONCLUSION: The article demonstrates the traits of the drug associated with its chemical, pharmacokinetics, stability, and other features, and illustrates their most useful characteristics for clinical application.PMID:38178658 | DOI:10.2174/0113816128272443231221101415 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 5, 2024 Category: Drugs & Pharmacology Authors: Alisha Sachdeva Monika Targhotra Meenakshi Kanwar Chauhan Monica Chopra Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
Role of Amphotericin B in the Treatment of Mucormycosis
CONCLUSION: The article demonstrates the traits of the drug associated with its chemical, pharmacokinetics, stability, and other features, and illustrates their most useful characteristics for clinical application.PMID:38178658 | DOI:10.2174/0113816128272443231221101415 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - January 5, 2024 Category: Drugs & Pharmacology Authors: Alisha Sachdeva Monika Targhotra Meenakshi Kanwar Chauhan Monica Chopra Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
