2024, a year of openness
Ann Biol Clin (Paris). 2024 Apr 19;82(1):5-6. doi: 10.1684/abc.2024.1872.NO ABSTRACTPMID:38638012 | DOI:10.1684/abc.2024.1872 (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Katell Peoc'h Source Type: research
80 years of Annales de Biologie Clinique: time for renewal!
Ann Biol Clin (Paris). 2024 Apr 19;82(1):7. doi: 10.1684/abc.2024.1879.NO ABSTRACTPMID:38638013 | DOI:10.1684/abc.2024.1879 (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Laurence Pi éroni Source Type: research
New anticoagulants in 2024: Development of factor XI and XIa inhibitors
Ann Biol Clin (Paris). 2024 Apr 19;82(1):9-23. doi: 10.1684/abc.2024.1865.ABSTRACTThrombosis remains one of the leading causes of death in the world. The history of anticoagulation has evolved considerably from non-specific drugs (i.e., heparins and vitamin K antagonists, VKA) to agents that directly target specific coagulation factors (i.e., argatroban, fondaparinux and direct oral anticoagulants, DOAC). Since the last decade, DOAC are widely used in clinical practice because of their ease to use, their favorable pharmacological profile and the fact that they do not require monitoring. However, despite having a better saf...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: N ûn K Bentounes Sophie Melicine Anne-C éline Martin David M Smadja Nicolas Gendron Source Type: research
Newborn screening in France: news and perspectives
Ann Biol Clin (Paris). 2024 Apr 19;82(1):24-31. doi: 10.1684/abc.2024.1869.ABSTRACTNewborn screening is a major public health concern. In France, it was established in 1972 with systematic screening for phenylketonuria. Subsequently, other screenings, including congenital hypothyroidism, congenital adrenal hyperplasia, cystic fibrosis, and sickle cell disease, were added. The introduction of tandem mass spectrometry in screening laboratories in 2020 enabled the inclusion of eight additional inherited metabolic diseases: aminoacidopathies (tyrosinemia type I, maple syrup urine disease, and homocystinuria), organic acidurias...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Emeline Gernez Estelle Roland Claire-Marie Dhaenens Gilles Renom Karine Mention Source Type: research
Programmed cell death in autoimmune diseases: ferroptosis
Ann Biol Clin (Paris). 2024 Apr 19;82(1):33-42. doi: 10.1684/abc.2024.1866.ABSTRACTFerroptosis is an iron dependent cell death driven by lipid peroxidation. Over the past decade, increasing evidence has confirmed that ferroptosis plays an irreplaceable role in the occurrence and development of many diseases, including various cancers, neurodegenerative diseases, cardiovascular diseases and autoimmune diseases. Autoimmune disease is an inflammatory disease characterized by the breakdown of immune tolerance. Nowadays, accumulating evidence indicates that ferroptosis is closely related to the pathogenesis of autoimmune diseas...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Jiantao Sun Lujuan Huang Jiawei Wang Yelang Hu Wenmin Wang Haihong Zhu Source Type: research
Motivational factors for early option choice by laboratory medicine residents in France
This study aimed to analyze these choice and motivational factors, since its implementation in 2017. A national survey was conducted among LM residents and former residents who underwent the early option choice process. A questionnaire was developed and sent to residents via Google Forms. Several groups of items corresponding to potential motivational factors were included and rated on a 5-point Likert scale. A psychometric analysis allowed to identify the main motivational factors. A total of 178 responses from 24 residency regions were recorded. The median age was 28 years, with a slight female predominance (52%), and th...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Enagnon Kazali Alidjinou Quentin Pomorski Maxence Bauvais Annabelle Dupont Fr édéric Grenouillet Myriam Labalette Boualem Sendid Thierry Brousseau Didier Hober Olivier Nicolas Source Type: research
Hormone anti-m üllérienne (AMH) en pédiatrie : établissement de valeurs de référence avec le dosage de l'AMH Fujirebio < sup > ® < /sup > Lumipulse G et comparaison avec le dosage Roche < sup > ® < /sup > Elecsys sur les m êmes échantillons pédiatriques
We described full pediatric gender and age-specific reference ranges for AMH using the Fujirebio® AMH assay on the Lumipulse G 600 II. The study was performed on 281 plasma samples collected in tubes with lithium heparin. The samples were from patients (135 males and 146 females) aged from 3 days to 22 years collected at the University Hospital Center of Tours. The Fujirebio® Lumipulse method showed excellent correlation with Roche® Elecsys but had a significant proportional positive bias. The data were used to propose pediatric reference values adapted to the Fujirebio® method. Our study described full pediatric gende...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Jean-Baptiste Delaye Olivier Le Tilly Emmanuel Enard Christine Collet Patrick Emond Diane Dufour-Rainfray Source Type: research
Le miR-224-5p r égulé sert de biomarqueur pour l'insuffisance hépatique aiguë pédiatrique et régule l'inflammation en modulant ZBTB20
This study focused on evaluating the clinical significance of miR-224-5p in PALF and revealing its potential molecular mechanism in regulating liver cell injury. This study enrolled 103 children with PALF and 55 healthy children without liver diseases. Serum miR-224-5p levels were compared between the two groups, and their clinical significance was estimated by analyzing the correlation with clinicopathological features and outcomes of PALF children. In vitro, a normal liver cell was treated with lipopolysaccharide (LPS), and cell growth and inflammation were assessed by CCK8 and ELISA assay. Upregulated miR-224-5p in PALF...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Qin Wang Gaoyin Zhang Mengmeng Zhang Yunxia Zhang Lianying Ruan Hengrui Hao Source Type: research
Use of LDBIO Diagnostics < sup > ® < /sup > TOXOPLASMA ICT IGG-IGM in association with Siemens Atellica < sup > ® < /sup > IM in toxoplasmosis serological screening
Ann Biol Clin (Paris). 2024 Apr 19;82(1):81-92. doi: 10.1684/abc.2024.1875.ABSTRACTAccording to French recommendations for serological screening of toxoplasmosis, some profiles must be confirmed by additional methods, extending the time taken to produce results. Thus, the Laborizon Bretagne technical platform in Nantes studied the place of the LDBIO Diagnostics® TOXOPLASMA ICT IGG-IGM (ICT) test in addition to Siemens Atellica® serology. IgG-/IgM+ and equivocal or weak positive IgG/IgM- (IgGEq/IgM-) profiles on Atellica® will be confirmed by ICT, Alinity® Abbott and Platelia® Biorad. Among the 66 IgGEq/IgM- profiles, ...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Mickael Fortun Julien L'hirondel Source Type: research
Fonction de l'ARNnc exosomal HEIH dans le carcinome h épatocellulaire associé au virus de l'hépatite B
This study aimed to investigate the expression of exosomal lncRNA-HEIH in B-HCC patients and explore its clinical significance. We collected blood samples from 60 B-HCC patients, 60 non-hepatitis virus-associated HCC (N-HCC) patients, and 50 healthy volunteers. Exosomal lncRNA-HEIH levels were measured by real-time PCR and analyzed for their correlation with patient prognosis using Kaplan-Meier analysis. Multivariate COX regression analysis was conducted to identify factors affecting patient outcomes. The effects of lncRNA-HEIH on carcinogenesis were also investigated by constructing a Huh7 cell line stably expressing the ...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Tao Yu Huiming Li Guijia Shen Qifang Wu Source Type: research
Evaluation of a new portable analyzer, HemoCue < sup > ® < /sup > Hb801, for hemoglobin point-of-care testing
Ann Biol Clin (Paris). 2024 Apr 19;82(1):103-111. doi: 10.1684/abc.2024.1868.ABSTRACTThe use of portable hemoglobin measuring devices is widespread. In this context, the company HemoCue® has put on the market a new device, the Hb801. It uses a whole blood absorbance measurement method and not the azidmethemoglobin measurement method used by HemoCue's older devices. We evaluated this new equipment on EDTA venous blood. Hb801 is lightweight, compact, requires a volume of 10 μL of blood and renders its result in less than a second. The repeatability and intermediate precision are close to the values expected according to Ri...
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Bryan Zamorano Yolla Sakr Fr édérique Galopin-Dubois Source Type: research
Microcristaux de cholest érol dans le liquide synovial et polyarthrite rhumatoïde
Ann Biol Clin (Paris). 2024 Apr 19;82(1):112-113. doi: 10.1684/abc.2024.1870.NO ABSTRACTPMID:38638024 | DOI:10.1684/abc.2024.1870 (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Jean-Marc Blouin Nicolas Poursac Sophie Gad Emmanuel Richard Source Type: research
Summary of the 32nd national meeting of the Coll ège National de Biochimie des Hôpitaux
Ann Biol Clin (Paris). 2024 Apr 19;82(1):114-124. doi: 10.1684/abc.2024.1878.NO ABSTRACTPMID:38638025 | DOI:10.1684/abc.2024.1878 (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - April 19, 2024 Category: Biochemistry Authors: Magali Annette-Reisch Édith Bigot-Corbel Valery Brunel Yohan Darrieux Patrick Ray Camille Richard Batiste Simonet Fr édéric Sobas Marie-H élène Tournoys Panagiotis Tsiamyrtzis Source Type: research
Inquilinus limosus, an atypical Gram-negative rod from lung transplant recipients and cystic fibrosis patients
Ann Biol Clin (Paris). 2024 Apr 1;82(2):1-2. doi: 10.1684/abc.2024.1876. Online ahead of print.NO ABSTRACTPMID:38616576 | DOI:10.1684/abc.2024.1876 (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - April 15, 2024 Category: Biochemistry Authors: Eric Farfour St éphane Corvec Thomas Guillard H élène Revillet Source Type: research
Inquilinus limosus, an atypical Gram-negative rod from lung transplant recipients and cystic fibrosis patients
Ann Biol Clin (Paris). 2024 Apr 1;82(2):1-2. doi: 10.1684/abc.2024.1876. Online ahead of print.NO ABSTRACTPMID:38616576 | DOI:10.1684/abc.2024.1876 (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - April 15, 2024 Category: Biochemistry Authors: Eric Farfour St éphane Corvec Thomas Guillard H élène Revillet Source Type: research
