An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
An Uncommon Case of Fungal Rhinosinusitis Caused by the Mold < em > Exserohilum rostratum < /em > in a Patient with Relapsed Acute Myeloid Leukemia: Case Report and Review of the Literature
We present here a patient with relapsed acute myeloid leukemia who was neutropenic for a prolonged period. Symptoms worsened during the hospital course, including left-sided sinus swelling, which was also noted on imaging. ENT performed a bedside endoscopy and biopsied an eschar forming in the left nasal cavity. This was ultimately found to be acute invasive rhinosinusitis due to infection with the mold Exserohilum rostratum The patient was started on Posaconazole and Amphotericin B. He eventually also underwent surgical debridement. Infections with this organism are very uncommon, as noted in our literature search. In the...
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: David Thomas Jeff Johnson Humberto Trejo Bittar Aliyah Baluch Source Type: research
Field Efficacy of Topical Nano-Liposomal Amphotericin B (Sina Ampholeish ®) Alone or in Combination with Glucantime® and Cryotherapy on Human Cutaneous Leishmaniasis
CONCLUSION: Sina Ampholeish® in combination with other standard protocols of treatment of CL is well tolerated and with acceptable clinical efficacy rate.PMID:38169758 | PMC:PMC10758084 | DOI:10.18502/ijpa.v18i4.14241 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - January 3, 2024 Category: Parasitology Authors: Zahra Alizadeh Mohammad Reza Shirzadi Gholam Reza Hassanpour Hossein Keshavarz Fatemeh Mohebali Seyed Ebrahim Eskandari Mohammad Zeinali Sedigheh Shirmohammad Mehdi Mohebali Source Type: research
Amphotericin B-Loaded Extracellular Vesicles Derived from < em > Leishmania major < /em > Enhancing Cutaneous Leishmaniasis Treatment through In Vitro and In Vivo Studies
CONCLUSION: EVs-AmB improved the efficacy of AmB in mouse skin lesions and reduced hepatorenal toxicity. Furthermore, EVs could be a promising nanoplatform for the delivery of AmB in CL caused by L. major.PMID:38169565 | PMC:PMC10758083 | DOI:10.18502/ijpa.v18i4.14260 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - January 3, 2024 Category: Parasitology Authors: Afshin Davari Homa Hajjaran Ali Khamesipour Mehdi Mohebali Fatemeh Mehryab Saeed Shahsavari Faezeh Shekari Source Type: research
Field Efficacy of Topical Nano-Liposomal Amphotericin B (Sina Ampholeish ®) Alone or in Combination with Glucantime® and Cryotherapy on Human Cutaneous Leishmaniasis
CONCLUSION: Sina Ampholeish® in combination with other standard protocols of treatment of CL is well tolerated and with acceptable clinical efficacy rate.PMID:38169758 | PMC:PMC10758084 | DOI:10.18502/ijpa.v18i4.14241 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - January 3, 2024 Category: Parasitology Authors: Zahra Alizadeh Mohammad Reza Shirzadi Gholam Reza Hassanpour Hossein Keshavarz Fatemeh Mohebali Seyed Ebrahim Eskandari Mohammad Zeinali Sedigheh Shirmohammad Mehdi Mohebali Source Type: research
Amphotericin B-Loaded Extracellular Vesicles Derived from < em > Leishmania major < /em > Enhancing Cutaneous Leishmaniasis Treatment through In Vitro and In Vivo Studies
CONCLUSION: EVs-AmB improved the efficacy of AmB in mouse skin lesions and reduced hepatorenal toxicity. Furthermore, EVs could be a promising nanoplatform for the delivery of AmB in CL caused by L. major.PMID:38169565 | PMC:PMC10758083 | DOI:10.18502/ijpa.v18i4.14260 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - January 3, 2024 Category: Parasitology Authors: Afshin Davari Homa Hajjaran Ali Khamesipour Mehdi Mohebali Fatemeh Mehryab Saeed Shahsavari Faezeh Shekari Source Type: research
