A Blood Filter Fights Deadly Inflammatory Response

A new blood filtration technology may prove to be life-saving for patients whose normally healthy inflammatory response to injury or illness has gone into overdrive, resulting in fatally high levels of cytokines in their blood. In an interview with MD+DI, Dr. Phillip Chan, MD, PhD, CEO of CytoSorbents Corp., explained that inflammation, and the production of substances called cytokines that drive inflammation, are the body’s natural response to heal injury or infection. But sometimes, the inflammatory response is so severe in such conditions as sepsis and infection, burn injuries, trauma, pancreatitis, liver failure, acute respiratory distress syndrome, and the stress of undergoing open heart surgery, that the body releases dangerously higher and higher levels of cytokines, often referred to as a cytokine storm. “The inflammation and cytokine storm can be so massive that they cause cell death and broad organ damage,” he said. “Ultimately, this can cause the failure of vital organs like the heart, lungs, kidneys, brain, and liver, leading to a very high risk of death,” he continued. Chan said there are currently no good ways to control this deadly inflammation, noting that standard anti-inflammatory drugs are not strong enough in these extreme cases. “On the other end of the spectrum, there are drugs like high doses of steroids or immunosuppressants that are very good at...
Source: MDDI - Category: Medical Devices Authors: Tags: Cardiovascular Source Type: news

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Most of the literature and the instructional information publications regarding facial plastic surgery procedures has historically been from North American or European sources. Because of that history, much of the focus and development of clinical surgical information and facial plastic procedures has been described utilizing a Caucasian patient base. However, there has been tremendous growth and expansion internationally in the interest in facial plastic procedures, and accordingly, the ethnic patient population base has greatly expanded.
Source: Facial Plastic Surgery Clinics of North America - Category: Cosmetic Surgery Authors: Tags: Foreword Source Type: research
Digital holography is a useful tool to image microscopic particles. Reconstructed holograms give high-resolution shape information ...
Source: Journal of the Optical Society of America A - Category: Physics Authors: Source Type: research
[WHO] I was greatly heartened by the global show of support demonstrated at the Global COVID-19 Summit hosted by the President of the United States of America, Joe Biden, on Wednesday, 22 September 2021.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
You can say one thing for Professor Mark Haub: He knows how to make a lesson stick. Haub, who teaches nutrition at Kansas State University, wanted to prove to his students that weight loss is simply about calories. So, for 10 weeks, the professor proceeded to eat an 1,800-calorie diet consisting of a Twinkie every three hours. He also dined on Doritos, Little Debbies, sugary cereal and other junk food. When he started, Haub tipped the scales at 201 pounds, which for his height was considered overweight. By the end of his snack-food spree, he had lost 27 pounds, putting him at a svelte 174. The story went viral, with the me...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: news
It’s Telehealth Awareness Week! Today on Health in 2 Point 00, we cover Pager raising $70 million, bringing their total to $132.6 million. German-based company Ovivia gets $80 million, bringing their total to $127 million. Meru Health raises $38 million, and NOCD raises $33 million. —Matthew Holt
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health in 2 Point 00 Health Tech Health Technology Jessica DaMassa Matthew Holt Ovivia Pager Source Type: blogs
We describe a successfully diagnosed and treated CHL-PTLD stage IV pediatric patient, 8 years after liver transplantation. The patient was treated with standard CHL (Children’s Cancer Group 5942 group 3) chemotherapy, rituximab and reduction of immunosuppressant. The patient remains in complete remission after 3 years with stable graft function. To our best knowledge, this is the first pediatric case report of a successfully treated stage IV CHL-PTLD after a liver transplant.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
Hepatitis-associated aplastic anemia (HAAA) has been reported in 23% to 33% of patients who received orthotopic liver transplantation (LT) for acute liver disease of unknown origin (nonviral hepatitis). In this situation, hematopoietic stem cell transplantation (HSCT) might be a curative option. Here the authors report on 6 patients who received HSCT after LT for nonviral HAAA hepatitis. The outcomes were interpreted in the context of recently reported immune suppressive therapy (IST) outcomes in 8 patients with HAAA and to HSCT outcomes in patients with HAAA who recovered from hepatitis without undergoing LT. All patients...
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
Conclusions: High ferritin and low hemoglobin levels, a high mean platelet volume, a high red cell distribution width, low weight (below the third percentile), and a short height (below the third percentile) may be associated with elevated cerebral blood flow velocities and an increased stroke risk in children with SCD. Children with such features should be closely followed-up through transcranial Doppler ultrasonography examination.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Original Articles Source Type: research
Conclusions: In this cohort, there seems to be an association between SCD and AILD; SC in this population was severe. Physicians should be aware of this and evaluate patients with SCD and elevated liver enzymes for AILD.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Original Articles Source Type: research
In the Netherlands, between 1985 and 2007 secular changes in the health care of patients with sickle cell disease (SCD) have taken place, such as penicillin prophylaxis, vaccination programs and stroke prevention. We investigated the number and causes of death in a cohort of 298 SCD patients, established in 2007, before introduction of neonatal screening, to determine preventable deaths. All patients were diagnosed with SCD before the age of 18 (median age at diagnosis 5.1 y). Their vital status was determined up to January 2017. After a total follow-up period of 4565 patient years and a median time of follow-up of ...
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Original Articles Source Type: research
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