Pharmacogenomics: The Science of Personalizing Drugs Based On DNA

Individuals share about 99.97 percent of their DNA and only the remaining 0.03 percent is responsible for the differences in skin, hair or eye color, height, shoe size or sunspots. Scientists discovered somewhat recently that our bodies also metabolize drugs differently so it would make sense to prescribe medications based on the knowledge hidden in our DNA. In some cases, physicians already do that. Here’s what you need to know about pharmacogenomics and the future of prescription drugs. It’s all in your genes Why do some people eat creamy French cakes all the time, only do sports when they have to run after the bus and still remain in shape? How come when others eat some chips, the next day they’ll gain two pounds? What exactly is the reason for some people not being able to drink coffee after 6 pm otherwise they will be up all night; and why do others have some double espresso at 11 pm and sleep around midnight as if nothing happened? The response is all in your genes. Well, more precisely how your organism’s metabolic processes work, which are determined by the double spiral. Genetics and genomics aim to uncover the most hidden secrets of our bodies, and how the human organism might respond to environmental factors. Two specific strands concentrate on metabolic issues: nutrigenomics and pharmacogenomics. The first one deals with food issues and the latter with the drug response of our bodies due to the genetic code. Generally, it argues that despit...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Pharma Genomics Medical Professionals Patients Researchers DNA dna testing drugs genetics Health Healthcare Innovation medication pharmacogenetics pharmacogenomics precision health precision medicine technology Source Type: blogs

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Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
CONCLUSION: High Galectin-3, MMP-9, and ST-2 are independently influenced to a certain degree by demographic, clinical and laboratory characteristics. However, no single characteristic was found to be commonly associated with all of the three biomarkers. PMID: 31438834 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
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Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
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Source: Journal of Applied Developmental Psychology - Category: Child Development Source Type: research
Publication date: Available online 23 August 2019Source: Food ChemistryAuthor(s): Cristian Dima, Stefan DimaAbstractCalcium and vitamin D3 were co-encapsulated in three types of water-in-oil-in-water (W/O/W) double emulsions stabilized with biopolymers: gum arabic, sodium alginate (Alg) and chitosan (Ch). Three calcium salts with different solubility were used: calcium carbonate (CaC), tricalcium phosphate (CaP) and calcium gluconate (CaG). In order to study the bioavailability of calcium and vitamin D3, the W/O/W double emulsions were subjected to digestion in simulated conditions using in vitro gastrointestinal models. T...
Source: Food Chemistry - Category: Food Science Source Type: research
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Source: Current Opinion in Food Science - Category: Food Science Source Type: research
TYPE 2 diabetes is a life-long condition that requires a person to overhaul aspects of their lifestyle to avert the risks. Mike Trenell, founder and CEO of changing Health sheds a light on a vital yet too often overlooked area of diabetes management - behavioural science.
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Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
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Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
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Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
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