The Opportunity for Women’s Health in Emerging Markets
In this month’s article, I explore issues relating to the health of women in emerging markets. I will recommend that pharma companies wishing to maximize the opportunity in women’s health need to start from an understanding of how women are viewed by society in these markets and challenge awareness, attitudes and access barriers that can lead to their health outcomes being sub-optimal. As a starting point, it is necessary to establish a working definition of women’s health. This isn’t as straightforward as it might seem, as women’s health can be considered at multiple levels. The conditions which most obviously fall under the ‘women’s health’ umbrella relate to women’s sex, their female biological characteristics. This branch of medicine is known as gynecology, derived from the Greek word for woman, “gyneco”. Typically the remit of gynecologists/OBGYNs, this includes reproductive medicine (in terms of either fertility or contraception) and the menopause, along with diseases of organs specific to the female anatomy, such as uterine, cervical and ovarian cancer. Although breast cancer technically affects men, too, it is approximately 100 times more common in women and therefore also typically considered a women’s health issue. Female sexual dysfunction is a growing, if controversial, area of interest for pharma. Hoping to follow in the footsteps of the mass erectile dysfu...
CONCLUSIONS:: Malingering was prevalent in the psychiatric emergency department, and suspicion of malingering was associated with disposition differences. Disposition was significantly influenced by both suspicion of malingering and the gains sought by patients. PMID: 30526343 [PubMed - as supplied by publisher]
CONCLUSIONS:: Among outpatients with psychotic disorders, response to item 9 of the PHQ-9 accurately identified those at increased short-term risk of a suicide attempt. PMID: 30526341 [PubMed - as supplied by publisher]
Authors: Gara MA, Minsky S, Silverstein SM, Miskimen T, Strakowski SM Abstract OBJECTIVE:: The authors examined electronic medical record (EMR) outpatient data to determine whether African Americans with schizophrenia or schizoaffective disorder were more likely than non-Latino whites to screen positive for major depression. METHODS:: EMR data for 1,657 patients at Rutgers University Behavioral Health Care certified community outpatient clinics were deidentified and accrued for 9 months starting July 1, 2017. A Fisher's exact test was used to compare differences in the proportion of patients with positive scree...
Publication date: Available online 12 December 2018Source: Journal of the American College of RadiologyAuthor(s): Felix M. Gonzalez, J. Matthew Kerchberger, Douglas D. Robertson, Yara Younan, Adam Singer, Walter A. Carpenter, Richard Duszak, James R. Roberson, Monica B. UmpierrezAbstractPurposeTo evaluate the appropriateness of MRI ordering practices and their effect on clinical management for nontraumatic knee pain at the primary care clinics of a large public urban hospital.Materials and MethodsIn all, 196 consecutive MRIs for nontraumatic knee pain ordered from primary care clinics in a large public urban hospital over ...
CONCLUSIONS: This study provides further evidence on the short-term variability of SI in very short time frames implying the need of assessing SI repeatedly in clinical and research settings. The associations between interpersonal variables and passive and active SI were only partial in line with assumptions of the Interpersonal Theory of Suicide. Overall, the effects were small warranting further investigation. PMID: 30530103 [PubMed - as supplied by publisher]
During the production of this paper, an error appeared in the title. The title should be, “Immune Checkpoint Inhibition Combined With Intracranial Stereotactic Radiation Therapy in Non-Small Cell Lung Cancer: Is There an Increasing Rate of Radionecrosis or Not? In Regards to Schapira et al, Huppeling et al and Colaco et al.”
Prostate cancer is the leading cause of cancer treatment –related years lived with disability for men worldwide.1 This has driven a disruptive change in management of favorable-risk prostate cancer such that nearly all National Comprehensive Cancer Network (NCCN) very low-risk patients are recommended conservative management rather than radical therapy. 2 Simultaneously, at the other end of the risk spectrum, treatment intensification with more potent systemic therapies has been the subject of recent trials for men with higher-risk disease (eg, NCT02772588).
In the above referenced article, portions of the text and table reading “CALGB 80801” should have read “CALGB 80101,” to correctly reflect the referenced Fuchs CS et al. publication and CALGB study. The authors regret the error.
The authors' letter and translational research work support the question posed in the review1,2: Are we at the tipping point for the era of real-time radiation therapy? The research by Dahele and Verbakel adds additional clinical evidence that real-time 3-dimensional image guided radiation therapy (3D IGRT) can be performed on standard-equipped cancer radiation therapy (RT) systems. Indeed, had it been published or known to us before we wrote the review, their clinical translation of markerless spine tracking3 would have been included as a fourth real-time 3D IGRT implementation on standard-equipped systems.
Multiple randomized studies have demonstrated that breast-conserving therapy (partial mastectomy plus whole breast radiation) can yield survival outcomes equivalent to those of mastectomy (1). However, newer population-based data suggest that breast cancer –specific survival and overall survival with breast-conserving therapy may actually be better than those with mastectomy (2-8). How is this possible? How can removal of the breast yield outcomes inferior to those of a therapy that leaves most of the breast intact and where in-breast failures are r eported to occur in approximately 5% to 10% of patients at 10 y...
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