Epidemiology and antimicrobial resistance patterns of bacterial meningitis among hospitalized patients at a tertiary care hospital in Saudi Arabia: a six-year retrospective study
ConclusionThe study highlights the substantial burden of bacterial meningitis among hospitalized patients, especially among high-risk groups. Emerging antimicrobial resistance emphasizes the need for optimized surveillance and stewardship. Future prospective research employing molecular techniques across multiple centers in the country is warranted to enhance understanding and guide public health strategies in Saudi Arabia. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 29, 2024 Category: Microbiology Source Type: research

Tick-Borne Bacterial Diseases in Europe: Threats to public health
ConclusionsBy integrating various pieces of information on these bacterial species, the paper aims to provide a comprehensive  resource for researchers and healthcare professionals addressing the impact of bacterial tick-borne diseases in Europe. This review underscores the importance of understanding the complex details influencing bacterial prevalence and transmission dynamics to better combat these emerging public he alth threats. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 27, 2024 Category: Microbiology Source Type: research

Evolution, control and success of combination therapy with Ampicilin-sulbactam/Ceftazidime-Avibactam during a Carbapenem-Resistant Acinetobacter baumannii outbreak in burn Intensive Care Unit
We present our findings on interpatient transmission, epidemic control measures, and the outcomes of a series of ten critically ill burn patients who were either colonized or infected with carbapenem-resistantAcinetobacter baumannii (CRAB). None of the five infected patients achieved clinical cure, and all experienced relapses. Microbiological failure was observed in 40% of the infected patients. The isolated CRAB strains were found to carry blaOXA −23 and armA resistance genes. Despite the lack of clinical cure, all five infected patients survived and were discharged from the Burn Intensive Care Unit. (Source: European ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 27, 2024 Category: Microbiology Source Type: research

Oligella spp.: A systematic review on an uncommon urinary pathogen
ConclusionOligella is an uncommon pathogen that can be underrecognized. Microbiologists should be prompt to prolong the incubation of agar media plated with urines when the direct examination showed Gram-negative coccobacilli. Carbapenems should probably be given for the empirical treatment. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 26, 2024 Category: Microbiology Source Type: research

MAST ® D72C test: a novel option for ESBL, AmpC and carbapenemase detection
ConclusionThese results show that the MAST ® D72C test can be a useful tool for the detection of ESBL- and AmpC-production in clinical laboratories. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 25, 2024 Category: Microbiology Source Type: research

Development and validation of an online dynamic nomogram system for pulmonary consolidation in children with Mycoplasma pneumoniae pneumonia
ConclusionsWe developed a dynamic online nomogram for predicting combined pulmonary consolidation in children with MP based on 7 variables for the first time. The predictive value and clinical benefit of the nomogram model were acceptable. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 24, 2024 Category: Microbiology Source Type: research

In vitro activity of cefiderocol against carbapenem-resistant Acinetobacter baumannii carrying various β-lactamase encoding genes
ConclusionsCefiderocol susceptibility was 60.7% in CRAB isolates. MIC50, MIC90 ofblaPER −1 positive andblaPER −1 negative groups were>  128/>128 and 0.25/>128  mg/L. A correlation between the presence ofblaPER −1 and cefiderocol resistance was observed (p <  0.0001). Among colistin-resistant isolates, the presence ofblaPER −1 was 47.1% and 75% of them were resistant to cefiderocol respectively. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 23, 2024 Category: Microbiology Source Type: research

Rubella virus-associated cutaneous granulomatous disease in an immunocompetent woman
(Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 22, 2024 Category: Microbiology Source Type: research

Molecular epidemiological and clinical infection characteristics analysis of Ralstonia
ConclusionWe established a sequence typing system with a relatively fine resolution and the PCR assay is a faster and more sensitive method for clinical identification ofRalstonia pickettii. ST9 is the most common sequence types ofRalstonia pickettii. The most common clinical characteristics ofRalstonia pickettii infected patients were cough, sputum, shortness of breath and pulmonary rales. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 19, 2024 Category: Microbiology Source Type: research

Clinical effectiveness of cefiderocol for the treatment of bloodstream infections due to carbapenem-resistant Acinetobacter baumannii during the COVID-19 era: a single center, observational study
ConclusionsCFDC could represent an effective and safe treatment option for CRAB BSI, especially in patients with bacteremic HAP/VAP and frail patients where the risk of acute renal failure during therapy should be avoided. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 18, 2024 Category: Microbiology Source Type: research

Evaluation of the JF5-based Aspergillus galactomannoprotein lateral flow device for diagnosing invasive aspergillosis in cancer patients
ConclusionThe AspLFD demonstrated good performance in diagnosing IA in cancer patients, especially those with solid tumours. The AspLFD is thus an alternative POCT, particularly when GM evaluations are not readily available. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 16, 2024 Category: Microbiology Source Type: research

Molecular epidemiology and resistance mechanisms of tigecycline-non-susceptible Acinetobacter baumannii isolated from a tertiary care hospital in Chongqing, China
AbstractWe studied 34 isolates of Tigecycline-Non-SusceptibleA. baumannii (TNAB) obtained from clinical specimens at a large tertiary care hospital in Chongqing, China. These 34 strains belonged to 8 different clones including ST195 (35.3%) and ST208 (17.7%). EBURST analysis found that these 8 ST types belonged to the Clonal Complex 92. Tigecycline resistance-associated genesadeR, adeS, adeL, adeN, rrf, rpsJ, and trm were detected in most strains. The expression level of the resistance-nodulation-cell division (RND) efflux pumps in TNAB strains was higher than the reference strain ATCC19606. 58.8% of strains had a decrease...
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 15, 2024 Category: Microbiology Source Type: research

Performance of two immunochromatographic tests in detecting KPC variants conferring resistance to ceftazidime-avibactam
(Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 15, 2024 Category: Microbiology Source Type: research

Diagnostic performance, stability, and acceptability of self-collected saliva without additives for SARS-CoV-2 molecular diagnosis
ConclusionsThis research supports the implementation of self-collected saliva as a comfortable and user-friendly alternative sample for SARS-CoV-2 diagnosis. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 13, 2024 Category: Microbiology Source Type: research

Detection of intrathecal IgG antibody for varicella and measles diagnosis by evaluation and comparison of a commercial IgG chemiluminescent immunoassay with two ELISAs
ConclusionThe findings indicate that CLIA testing can improve antibody detection in CSF samples, aiding the diagnosis of infectious neurological impairments. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 13, 2024 Category: Microbiology Source Type: research