European Journal of Clinical Microbiology and Infectious Diseases 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Racemose neurocysticercosis simulating tuberculous meningitis
We report a patient with racemose neurocysticercosis, highlighting the diagnostic and management issues. A 37-year-old male had headaches, fever, and seizures for 8 months. He had a positive tuberculin test, cerebrospinal fluid pleocytosis, and hydrocephalus and exudates on MRI. His symptoms rapidly resolved following antitubercular and prednisolone treatment. After 2 months, he was readmitted with headache and vomiting, and his brain MRI revealed communicat ing hydrocephalus with a cyst in the lateral ventricle and subarachnoid space, which was confirmed as neurocysticercosis on the third ventriculostomy. The patient w...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 22, 2022 Category: Microbiology Source Type: research
Ancient DNA confirmation of lepromatous leprosy in a skeleton with concurrent osteosarcoma, excavated from the leprosarium of St. Mary Magdalen in Winchester, Hants., UK
AbstractTo establish a biological profile and disease aetiologies for one of four burials recovered during a Time Team dig at the St. Mary Magdalenleprosarium, Winchester, UK in AD 2000. Osteological techniques were applied to estimate age at death, biological sex, stature and pathology. Visual assessment of the material was supplemented by radiographic examination. Evidence for leprosy DNA was sought using ancient DNA (aDNA) analysis. The remains are those of a male individual excavated from a west –east aligned grave. The skeleton shows signs of two pathologies. Remodelling of the rhino-maxillary area and degenerative ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 17, 2022 Category: Microbiology Source Type: research
Comparison between culture-positive and culture-negative septic shock in patients in the emergency department
This study aimed to compare clinical characteristics and outcomes of patients with culture-negative septic shock (CNSS) and culture-positive septic shock (CPSS) in the emergency department. We also assessed the differences in duration and de-escalation timing of antibiotic administration between the two groups. This single-center, retrospective, case –control study included adult patients diagnosed with septic shock in the emergency department between January 1, 2019 and March 31, 2020. They were divided into the CNSS and CPSS groups based on their culture results. The baseline characteristics, infection sites, culture t...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 15, 2022 Category: Microbiology Source Type: research
Molecular analysis of OXA-48-producing Escherichia coli in Switzerland from 2019 to 2020
This study describes the epidemiology of OXA-48-producingE. coli isolates submitted to the Swiss National Reference Center for Emerging Antibiotic Resistance (NARA) between January 2019 and December 2020. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 14, 2022 Category: Microbiology Source Type: research
Bordetella pertussis population changes under whole-cell and acellular pertussis vaccines-induced immunity selection pressure in Poland
(Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 14, 2022 Category: Microbiology Source Type: research
Follow-up blood cultures in Staphylococcus aureus bacteremia: a probability-based optimization
AbstractStaphylococcusaureus bacteremia (SAB) is a relevant finding which prompts a thorough diagnostic work-up. Follow-up blood cultures (BC) are essential in this work-up. We investigate the probability of detecting an ongoing bacteremia after initiation of active therapy according to the number of BC taken at key time points. A retrospective analysis of all patients with SAB in a 6-year period was performed. Total number of BCs taken and the positivity was registered for each day after start of therapy. A positivity-rate was corrected using a logistic mixed effects model. Observed detection frequencies were applied to c...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 6, 2022 Category: Microbiology Source Type: research
Safety and efficacy of phage therapy in difficult-to-treat infections: studies in Chinese literature
(Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 6, 2022 Category: Microbiology Source Type: research
VanA-Enterococcus faecalis in Poland: hospital population clonal structure and vanA mobilome
AbstractThe aim of our study was to characterize the epidemiological situation concerning nosocomial vancomycin-resistantEnterococcus faecalis of VanA-phenotype (VREfs-VanA) in Poland by investigating their clonal relationships and thevanA-associated mobilome. One-hundred twenty-five clinical isolates of VREfs-VanA collected between 2004 and 2016 were studied by phenotypic assays, multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE), PCR detection of plasmid-specific genes, and Tn1546 structure and localization mapping. Selected isolates were subjected to PFGE-S1, Southern hybridization, genomic seque...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 3, 2022 Category: Microbiology Source Type: research
Retrospective analysis of a large single cohort of Enterobacteriaceae producing extended-spectrum B-lactamase (E-ESBL) patients: incidence, microbiology, and mortality
AbstractWe conducted a retrospective study from 2005 to 2019 to describe the epidemiology and mortality of enterobacterial producing extended-spectrum β-lactamase (E-ESBL) infections in our university hospital over a 17-year period of time. Clinical and microbiological data were extracted from different software used for continuous surveillance. Stool samples from systematic screening for E-ESBL colonization were excluded from the study. The inci dence rate of infected patient was calculated by E-ESBL species and by year. A comparison of mortality rate in patients with bloodstream infections versus other types of infectio...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 2, 2022 Category: Microbiology Source Type: research
Missed pertussis diagnosis during co-infection with Bordetella holmesii
AbstractThe purpose of this study is to identify predictive factors associated with missed diagnosis ofB. pertussis–B. holmesii co-infection by assessing the analytical performance of a commercially available multiplexed PCR assay and by building a prediction model based on clinical signs and symptoms for detecting co-infections. This is a retrospective study on the electronic health records of all clinical samples that tested positive to eitherB. pertussis orB. holmesii from January 2015 to January 2018 at Geneva University Hospitals. Multivariate logistic regression was used to build a model for co-infection prediction...
Source: European Journal of Clinical Microbiology and Infectious Diseases - September 1, 2022 Category: Microbiology Source Type: research
Clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in children in China
AbstractInvasiveSalmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoidSalmonella infections is increasingly recognized with the improvement of laboratory detection capacity and techniques. A retrospective multicenter study was conducted to analyze the clinical profiles and antimicrobial resistance patterns of invasiveSalmonella infections in hospitalized children in China during 2016 –2018. A total of 130 children with invasiveSalmonella infections were included with the median age of 1...
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 30, 2022 Category: Microbiology Source Type: research
Community-acquired hypervirulent Klebsiella pneumoniae invasive infection in critically ill patients who dramatically improved
(Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 27, 2022 Category: Microbiology Source Type: research
Development of the invasive candidiasis discharge [I Can discharge] model: a mixed methods analysis
This study aimed to assess echinocandin use at hospital discharge and develop a transition of care (TOC) model to facilitate discharge for patients with IC. This was a mixed method study design that used epidemiologic assessment to better understand echinocandin use at hospital discharge TOC. Using grounded theory methodology focused on patients given echinocandins during their last day of hospitalization, a TOC model for patients with IC, the invasive candidiasis [I Can] discharge model was developed to better understand discharge barriers. A total of 33% (1405/4211) echinocandin courses were continued until the last day ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 25, 2022 Category: Microbiology Source Type: research
Metagenomic next-generation sequencing restores the diagnosis of a rare infectious complication of B cell depletion
AbstractA 45-year-old female patient receiving rituximab for B cell non-Hodgkin follicular lymphoma presented unexplained recurrent fever, abdominal discomfort, and pollakiuria. We performed shotgun metagenomic sequencing from peri-kidney collection that identified a co-infection withMycoplasma hominis andUreaplasma urealyticum. The patient recovered with sequelae after appropriate antibiotic treatment was given. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 24, 2022 Category: Microbiology Source Type: research
A systematic review and meta-analysis on the accuracy of rapid immunochromatographic tests for dengue diagnosis
AbstractRapid immunochromatographic tests are frequently used to diagnose dengue due to their easy use, low cost, and fast response. A high level of accuracy is essential for rapid diagnostic tests to support their large-scale use. Thus, this systematic review aims to evaluate the accuracy of rapid dengue diagnostic tests. The investigation was run through the following databases: LILACS, Medline (Pubmed), CRD, The Cochrane Library, Trip Medical Database, and Google Scholar. To solve difficulties, two independent reviewers performed document screening and selection. ELISA assay was adopted as a reference test because of se...
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 20, 2022 Category: Microbiology Source Type: research
