European Journal of Clinical Microbiology and Infectious Diseases 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Pneumococcal vaccination status among cirrhotic patients in Italy: a neglected topic
AbstractTo date, few reports have evaluated the pneumococcal vaccination status in cirrhotic patients. No data are available for European countries. We have explored this topic and the potential independent predictors motivating lack of vaccination in Italy. Between January 1st and June 30th 2022, 1419 cirrhotic patients of any etiology were consecutively enrolled in an observational, prospective study at 8 referral centers in Italy. Adjusted odds ratios (ORs) for the association with lack of vaccination were evaluated by multiple logistic regression analysis. Overall vaccine coverage was 17.9% (8.9% in patients< 65 yea...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 12, 2023 Category: Microbiology Source Type: research
Assessing the quality of the anaerobic environment — a method developed to support EUCAST disk diffusion of anaerobic bacteria
AbstractThe purpose of this study is to establish a method for assessing the anaerobic environment for EUCAST disk diffusion antimicrobial susceptibility testing (AST) of anaerobic bacteria on fastidious anaerobe agar with 5% mechanically defibrinated horse blood (FAA-HB). The method utilizes the association between a decrease in the metronidazole disk zone diameter and increasing oxygen levels with an aerotolerantClostridium perfringens strain DSM 25589 (CCUG 75076 and NCTC 14679). TheC. perfringens strain was tested on FAA-HB with a McFarland 1 inoculum and a metronidazole 5 μg disk. FAA-HB was incubated for 16–20 h a...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 12, 2023 Category: Microbiology Source Type: research
Epidemiology and antimicrobial resistance profile of Neisseria gonorrhoeae in Catalonia, Spain, 2016 –2019
AbstractAntimicrobial resistance data forNeisseria gonorrhoeae is globally sparse and resistant strains are emerging in Catalonia. We aim to describe epidemiological and antimicrobial resistance in all patients infected withN. gonorrhoeae during the period from 2016 to 2019, using available antimicrobial susceptibility data. We retrospectively analysed confirmed N. gonorrhoeae cases notified to Catalonia ’s microbiological reporting system. Antibiotic susceptibility testing (azithromycin, cefixime, ceftriaxone, ciprofloxacin, penicillin, spectinomycin, and tetracycline) was assessed using clinical breakpoints publish...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 10, 2023 Category: Microbiology Source Type: research
Group B streptococci (GBS) strains evading molecular diagnostics showed novel chromosomal deletions encompassing the CAMP-factor (cfb) encoding gene
AbstractA highly conserved fragment adjacent to thecfb gene encoding the CAMP factor is the target of PCR-based molecular diagnostic systems for the identification ofS. agalactiae (group B streptococci (GBS)). Six PCR-negative, culture-positive GBS strains were whole genome sequenced to assess why they escaped molecular diagnostics. GBS strains did not constitute a clonal cluster and presented variably sized chromosomal deletions (from 7 to 33 kb) which always included thecfb gene, a finding never described before. GBS strains that escape molecular diagnostics are considered rare; however, they can cause false-negative res...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 9, 2023 Category: Microbiology Source Type: research
Profile analysis of emerging respiratory virus in children
The objective of our study was to evaluate clinical data from a viral panel performed in children hospitalized with SARS or COVID-19 in the infirmary or ICU of 5 pediatric hospitals in the city of Goi ânia, Goiás, Brazil. Demographic, clinical, and laboratory data were collected for analysis, and data on the outcomes underwent statistical treatment. A total of 128 patients were selected for the study, 54% of whom were male and 46% female. The viral panel included rhinovirus, COVID-19, metapneum ovirus, adenovirus, and parainfluenza. Descriptive analyses of age profile showed differences in the involvement of particular v...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 9, 2023 Category: Microbiology Source Type: research
Molecular detection of Nocardia: development and application of a real-time PCR assay in sputum and bronchoalveolar lavage fluid samples
In this study, our objective was to develop and validate a new TaqMan real-time PCR (qPCR) assay for rapidly detectingNocardia spp. in respiratory samples. Based on published sequence data, primers in a conserved region of the 16S rRNA gene and a probe within that region that was specific forNocardia were designed. The distinction effect of the qPCR assay was assessed betweenNocardia and other respiratory-associated bacteria. Furthermore, the specificity and sensitivity of the assay were evaluated in respiratory clinical samples (n = 205), compared to the results of 16S rRNA gene amplicon sequencing and clinical diagno...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 9, 2023 Category: Microbiology Source Type: research
The interaction between liver cirrhosis, infection by Streptococcus bovis, and colon cancer
In conclusion, risk of colorectal neoplasm is high among cirrhotic patients withS. gallolyticus bacteremia. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 5, 2023 Category: Microbiology Source Type: research
Clinical epidemiology of pulmonary aspergillosis in hospitalized patients and contribution of Cyp51A, Yap1, and Cdr1B mutations to voriconazole resistance in etiologic Aspergillus species
AbstractPulmonary aspergillosis is a life-threatening fungal infection with worldwide distribution. In the present study, clinical epidemiology of pulmonary aspergillosis and antifungal susceptibility of etiologicAspergillus species were evaluated in one-hundred fifty patients with special focus on the frequency of voriconazole resistance. All the cases were confirmed by the clinical pictures, laboratory findings, and isolation of etiologicAspergillus species which belonged to two major species, i.e.,A. flavus andA. fumigatus. Seventeen isolates displayed voriconazole MIC greater than or equal to the epidemiological cutoff...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 5, 2023 Category: Microbiology Source Type: research
In vitro activities of omadacycline, eravacycline, cefiderocol, apramycin, and comparator antibiotics against Acinetobacter baumannii causing bloodstream infections in Greece, 2020 –2021: a multicenter study
AbstractResistance ofAcinetobacter baumannii to multiple clinically important antimicrobials has increased to very high rates in Greece, rendering most of them obsolete. The aim of this study was to determine the molecular epidemiology and susceptibilities ofA. baumannii isolates collected from different hospitals across Greece. Single-patientA. baumannii strains isolated from blood cultures (n = 271), from 19 hospitals, in a 6-month period (November 2020 –April 2021) were subjected to minimum inhibitory concentration determination and molecular testing for carbapenemase, 16S rRNA methyltransferase andmcr gene detection ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 3, 2023 Category: Microbiology Source Type: research
Parvimonas micra a new potential pathogen in hospitalized patients: a case series from 2015 –2022
We describe here a large series of hospitalized patients diagnosed withParvimonas micra infections and discuss the clinical and therapeutic management and the outcome of these infections. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 3, 2023 Category: Microbiology Source Type: research
An assessment of the downstream implications of blood culture collection and transit
This study aims to explore the effect of transit times (TT) and culture volume, on time to microbiological diagnosis and patient outcomes. Blood cultures received between 1st March and 31st July 2020/21 were identified. TT, time in incubator (TII), and for positive samples, request to positivity times (RPT) were calculated. Demographic details were recorded for all samples, and culture volume, length of stay (LoS), and 30-day mortality for patients with positive samples. Statistical analysis examined how culture volume and TT effected culture positivity and outcome; in the context of the 4-h national TT target. Totally, 14...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 2, 2023 Category: Microbiology Source Type: research
Antenatal pyelonephritis: a three-year retrospective cohort study of two Irish maternity centres
AbstractPyelonephritis affects 1 –2% of pregnant women, and is associated with significant maternal and fetal morbidity. Antenatal pyelonephritis has been associated with PPROM (preterm premature rupture of membranes), preterm labour, low birth weight (LBW) and prematurity. A three-year retrospective dual-centre cohort study of a ntenatal pyelonephritis cases was conducted in two neighbouring Irish maternity hospitals – the Rotunda Hospital (RH) and the National Maternity Hospital (NMH). Patient demographics, clinical presentation, investigations, management and maternal/neonatal outcomes were recorded. A total of 4...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 1, 2023 Category: Microbiology Source Type: research
Prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation comparing tuberculin skin test and interferon-gamma release assay
AbstractThe aim of this study was to evaluate the prevalence of latentMycobacterium tuberculosis infection in hematopoietic stem cell transplantation candidates, using tuberculin skin test and QuantiFERON-TB Gold-Plus, in a high-burden tuberculosis country. Adult candidates for hematopoietic stem cell transplantation performed both tests before and those submitted to transplantation were followed up for 12 months. The prevalence of latentMycobacterium tuberculosis infection was 17.1% and a moderate agreement between QuantiFERON-TB Gold-Plus and tuberculin skin test was observed in this population. Previous tuberculosis exp...
Source: European Journal of Clinical Microbiology and Infectious Diseases - May 1, 2023 Category: Microbiology Source Type: research
Incidence, seasonal pattern, and clinical manifestations of Streptococcus dysgalactiae subspecies equisimilis bacteremia; a population-based study
AbstractStreptococcus dysgalactiae subspeciesequisimilis (SDSE) is a human pathogen causing severe invasive infections. Population-based studies on SDSE bacteremia are limited. The purpose of this study was to investigate the incidence, seasonal pattern, clinical manifestations, and recurrence of SDSE bacteraemia. Records regarding patients aged ≥ 18 years with SDSE bacteremia in the Pirkanmaa health district in August 2015 to July 2018 were retrospectively reviewed. A total of 230 SDSE bacteremia episodes were identified, with 217 episodes (involving 211 patients) available for analysis. The mean annual incidence ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 29, 2023 Category: Microbiology Source Type: research
Ceftriaxone for methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia: a matter of dosages?
(Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 29, 2023 Category: Microbiology Source Type: research
