GSE176342 Bulk transcriptomics analysis of SIX2+CITED1+ cells from Wilms Tumor
Conclusion: Our study represents the first transcriptomic characterization of Wilms Tumor cancer stem cells (SIX2+CITED1+) against human fetal kidney SIX2+CITED1+ cells. Identifying specify gene expression and signaling pathway profiles across different subtypes of Wilms Tumor and against human fetal kidney SIX2+CITED1+ cells. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - January 8, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
A rare case of extrarenal Wilms tumor of the uterine corpus: comprehensive genomic profile and review of the literature
We present the case of an adult woman who underwent total abdominal hysterectomy due to a uterine mass causing persistent abdominal pain. The characteristic triphasic morphology (composed of epithelial, stromal, and blastemal elements) supported by a broad immunohistochemical panel, along with the imaging exclusion of a renal neoplasm, was diagnostic of WT of the uterus. For the first time, a comprehensive genomic profiling of a uterine primary WT was also performed by next-generation sequencing, disclosing alterations at the level of copy number variations in the genes ERBB2, FGFR23, FGF6, FGFR2, and RPS6KB1. All previous...
Source: Pathologica - January 5, 2024 Category: Pathology Authors: Lara Alessandrini Angela Guerriero Giada Munari Biancamaria Del Forno Luisa Santoro Matteo Marchetti Margherita Nardin Roberto Tozzi Matteo Fassan Angelo Paolo Dei Tos Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
A rare case of extrarenal Wilms tumor of the uterine corpus: comprehensive genomic profile and review of the literature
We present the case of an adult woman who underwent total abdominal hysterectomy due to a uterine mass causing persistent abdominal pain. The characteristic triphasic morphology (composed of epithelial, stromal, and blastemal elements) supported by a broad immunohistochemical panel, along with the imaging exclusion of a renal neoplasm, was diagnostic of WT of the uterus. For the first time, a comprehensive genomic profiling of a uterine primary WT was also performed by next-generation sequencing, disclosing alterations at the level of copy number variations in the genes ERBB2, FGFR23, FGF6, FGFR2, and RPS6KB1. All previous...
Source: Pathologica - January 5, 2024 Category: Pathology Authors: Lara Alessandrini Angela Guerriero Giada Munari Biancamaria Del Forno Luisa Santoro Matteo Marchetti Margherita Nardin Roberto Tozzi Matteo Fassan Angelo Paolo Dei Tos Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
A rare case of extrarenal Wilms tumor of the uterine corpus: comprehensive genomic profile and review of the literature
We present the case of an adult woman who underwent total abdominal hysterectomy due to a uterine mass causing persistent abdominal pain. The characteristic triphasic morphology (composed of epithelial, stromal, and blastemal elements) supported by a broad immunohistochemical panel, along with the imaging exclusion of a renal neoplasm, was diagnostic of WT of the uterus. For the first time, a comprehensive genomic profiling of a uterine primary WT was also performed by next-generation sequencing, disclosing alterations at the level of copy number variations in the genes ERBB2, FGFR23, FGF6, FGFR2, and RPS6KB1. All previous...
Source: Pathologica - January 5, 2024 Category: Pathology Authors: Lara Alessandrini Angela Guerriero Giada Munari Biancamaria Del Forno Luisa Santoro Matteo Marchetti Margherita Nardin Roberto Tozzi Matteo Fassan Angelo Paolo Dei Tos Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
A rare case of extrarenal Wilms tumor of the uterine corpus: comprehensive genomic profile and review of the literature
We present the case of an adult woman who underwent total abdominal hysterectomy due to a uterine mass causing persistent abdominal pain. The characteristic triphasic morphology (composed of epithelial, stromal, and blastemal elements) supported by a broad immunohistochemical panel, along with the imaging exclusion of a renal neoplasm, was diagnostic of WT of the uterus. For the first time, a comprehensive genomic profiling of a uterine primary WT was also performed by next-generation sequencing, disclosing alterations at the level of copy number variations in the genes ERBB2, FGFR23, FGF6, FGFR2, and RPS6KB1. All previous...
Source: Pathologica - January 5, 2024 Category: Pathology Authors: Lara Alessandrini Angela Guerriero Giada Munari Biancamaria Del Forno Luisa Santoro Matteo Marchetti Margherita Nardin Roberto Tozzi Matteo Fassan Angelo Paolo Dei Tos Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
MicroRNA-193a Promotes Apoptosis in Retinal Neuronal Cells in Early-Stage Diabetic (DM) Rat via Wilms' Tumor Gene 1
CONCLUSION: miR-193a could inhibit early retinal neuronal cell apoptosis in DM rats by targeting and negatively regulating WT1 expression.PMID:38182143 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - January 5, 2024 Category: Laboratory Medicine Authors: Juan Yu Kehai Che Chong Gao Xuemei Pu Lijun Ren Source Type: research
