Crocin improves the renal autophagy in rat experimental membranous nephropathy via regulating the SIRT1/Nrf2/HO-1 signaling pathway
Ren Fail. 2023;45(2):2253924. doi: 10.1080/0886022X.2023.2253924. Epub 2023 Sep 19.ABSTRACTMembranous nephropathy (MN) is a glomerular disease. Crocin is isolated from saffron and gardenia. Its antioxidant, anti-inflammatory, anti-hyperlipidemic, anti-atherosclerotic, anti-tumor, free-radical scavenging and neuroprotective activities have been well established. We investigated the biological functions of crocin and its related mechanisms in MN. We established an experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum. The rats were divided into sham, sham + crocin, PHN, PHN + crocin, and PHN +...
Source: Renal Failure - September 19, 2023 Category: Urology & Nephrology Authors: Hongyan Liu Hong Cheng Hongyun Wang Qiong Wang Jun Yuan Source Type: research

Magnesium Sulfate in Pediatric Abdominal Cancer Surgery: Safety and Efficacy in Ultrasound-Guided Transversus Abdominis Plane (US-TAP) Block in Conjugation with Levobupivacaine
CONCLUSION: We conclude that adding magnesium sulphate as an adjuvant to local anaesthetic in US-TAP block for pain management in pediatric abdominal cancer surgeries resulted in better and longer analgesia, with less consumption of rescue analgesics with no serious side effects.PMID:37719936 | PMC:PMC10505031 | DOI:10.2147/LRA.S425649 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - September 18, 2023 Category: Anesthesiology Authors: Fatma El Sherif Doaa Gomaa Sayed Khaled Mohamed Fares Sahar Abdel-Baky Mohamed Amira Mahmoud Osman Ahmed Kamal Sayed Shereen Mamdouh Kamal Source Type: research

A pancreatic adenocarcinoma mimicking hepatoid carcinoma of uncertain histogenesis: A case report and literature review
Oncol Lett. 2023 Aug 28;26(4):442. doi: 10.3892/ol.2023.14029. eCollection 2023 Oct.ABSTRACTIn rare cases, metastatic adenocarcinomas of different origin may exhibit the features of hepatoid carcinoma (HC), a rare malignant epithelial tumor, most commonly occurring in the ovaries and stomach, as well as in the pancreas and biliary ducts. A case of a 72-year-old female patient who developed a highly aggressive, poorly differentiated pancreatic ductal adenocarcinoma with peritoneal carcinomatosis, demonstrating hepatoid differentiation upon conventional hematoxylin and eosin staining is reported in the present study. The pat...
Source: Oncology Letters - September 18, 2023 Category: Cancer & Oncology Authors: Andreea Iliesiu Radu-Valeriu Toma Ana Maria Ciongariu Radu Costea Narcis Zarnescu Liviu B îlteanu Source Type: research

Magnesium Sulfate in Pediatric Abdominal Cancer Surgery: Safety and Efficacy in Ultrasound-Guided Transversus Abdominis Plane (US-TAP) Block in Conjugation with Levobupivacaine
CONCLUSION: We conclude that adding magnesium sulphate as an adjuvant to local anaesthetic in US-TAP block for pain management in pediatric abdominal cancer surgeries resulted in better and longer analgesia, with less consumption of rescue analgesics with no serious side effects.PMID:37719936 | PMC:PMC10505031 | DOI:10.2147/LRA.S425649 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - September 18, 2023 Category: Anesthesiology Authors: Fatma El Sherif Doaa Gomaa Sayed Khaled Mohamed Fares Sahar Abdel-Baky Mohamed Amira Mahmoud Osman Ahmed Kamal Sayed Shereen Mamdouh Kamal Source Type: research

A pancreatic adenocarcinoma mimicking hepatoid carcinoma of uncertain histogenesis: A case report and literature review
Oncol Lett. 2023 Aug 28;26(4):442. doi: 10.3892/ol.2023.14029. eCollection 2023 Oct.ABSTRACTIn rare cases, metastatic adenocarcinomas of different origin may exhibit the features of hepatoid carcinoma (HC), a rare malignant epithelial tumor, most commonly occurring in the ovaries and stomach, as well as in the pancreas and biliary ducts. A case of a 72-year-old female patient who developed a highly aggressive, poorly differentiated pancreatic ductal adenocarcinoma with peritoneal carcinomatosis, demonstrating hepatoid differentiation upon conventional hematoxylin and eosin staining is reported in the present study. The pat...
Source: Oncology Letters - September 18, 2023 Category: Cancer & Oncology Authors: Andreea Iliesiu Radu-Valeriu Toma Ana Maria Ciongariu Radu Costea Narcis Zarnescu Liviu B îlteanu Source Type: research

Magnesium Sulfate in Pediatric Abdominal Cancer Surgery: Safety and Efficacy in Ultrasound-Guided Transversus Abdominis Plane (US-TAP) Block in Conjugation with Levobupivacaine
CONCLUSION: We conclude that adding magnesium sulphate as an adjuvant to local anaesthetic in US-TAP block for pain management in pediatric abdominal cancer surgeries resulted in better and longer analgesia, with less consumption of rescue analgesics with no serious side effects.PMID:37719936 | PMC:PMC10505031 | DOI:10.2147/LRA.S425649 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - September 18, 2023 Category: Anesthesiology Authors: Fatma El Sherif Doaa Gomaa Sayed Khaled Mohamed Fares Sahar Abdel-Baky Mohamed Amira Mahmoud Osman Ahmed Kamal Sayed Shereen Mamdouh Kamal Source Type: research

A pancreatic adenocarcinoma mimicking hepatoid carcinoma of uncertain histogenesis: A case report and literature review
Oncol Lett. 2023 Aug 28;26(4):442. doi: 10.3892/ol.2023.14029. eCollection 2023 Oct.ABSTRACTIn rare cases, metastatic adenocarcinomas of different origin may exhibit the features of hepatoid carcinoma (HC), a rare malignant epithelial tumor, most commonly occurring in the ovaries and stomach, as well as in the pancreas and biliary ducts. A case of a 72-year-old female patient who developed a highly aggressive, poorly differentiated pancreatic ductal adenocarcinoma with peritoneal carcinomatosis, demonstrating hepatoid differentiation upon conventional hematoxylin and eosin staining is reported in the present study. The pat...
Source: Oncology Letters - September 18, 2023 Category: Cancer & Oncology Authors: Andreea Iliesiu Radu-Valeriu Toma Ana Maria Ciongariu Radu Costea Narcis Zarnescu Liviu B îlteanu Source Type: research

Laparoscopic nephron-sparing surgery and laparoscopic nephrectomy for Wilms' tumor
CONCLUSIONS: This report demonstrates the feasibility of LN in children with Wilms' tumors. The patients should be carefully selected and specific training in laparoscopy is necessary, particularly with regard to laparoscopic heminephrectomy.PMID:37680728 | PMC:PMC10481445 | DOI:10.5114/wiitm.2022.123115 (Source: Videosurgery and Other Miniinvasive Techniques)
Source: Videosurgery and Other Miniinvasive Techniques - September 8, 2023 Category: Surgery Authors: Maciej Murawski Joanna Stefanowicz Marcin Łosin Andrzej Go łębiewski Piotr Czauderna Source Type: research