Correlation between maternal and umbilical cord 25-hydroxy-vitamin D levels over a range of values. A prospective observational study from the United Arab Emirates
by Magnus Jutell, Shakura Bhat, Maria Lindstrom Bagge, Per-Erik Isberg, Nana Wiberg
Worldwide vitamin D insufficiency is remarkably prevalent in both children and adults, including pregnant women. The total amount of the vitamin is best measured by 25-hydroxy-vitamin D (25(OH)D), which is a measurement of total serum cholecalciferol 25(OH)D3 and ergocalciferol 25(OH)D2. There is a known correlation between maternal and umbilical cord blood (UCB) 25(OH)D; however, whether specific maternal demographics or comorbidities influence the correlation remains uncertain. This prospective observational study was designed to study i...
Source: PLoS One - April 23, 2024 Category: Biomedical Science Authors: Magnus Jutell Source Type: research
Molecules, Vol. 29, Pages 1872: Analysis of Volatile Aroma Components in Different Parts of Shiitake Mushroom (Lentinus edodes) Treated with Ultraviolet C Light-Emitting Diodes Based on Gas Chromatography & ndash;Ion Mobility Spectroscopy
In this study, a comparison of UVC-LED irradiation treatment on the flavor profiles in various parts of shiitake mushrooms was conducted using gas chromatography–ion mobility spectrometry (GC-IMS) and sensory analysis. Sixty-three volatile compounds were identified in shiitake mushrooms. The fresh shiitake mushrooms were characterized by the highest values of raw mushroom odors. After UVC-LED treatment, the content of C8 alcohols decreased, especially that of 1-octen-3-ol, while the content of aldehydes increased, especially the content of nonanal and decanal. The score of fatty and green odors was enhanced. ...
Source: Molecules - April 19, 2024 Category: Chemistry Authors: Daihua Hu Yulin Wang Fanshu Kong Danni Wang Chingyuan Hu Xu Yang Xiaohua Chen Wang Chen Zili Feng Tags: Article Source Type: research
The antimicrobial effect of different vitamin D compounds on < em > Streptococcus mutans < /em > and their impact on glycosyltransferase expression
CONCLUSION: Vitamin D2 and D3 inhibited S. mutans mediated pH drop in sucrose supplemented cultures and altered glycosyltransferase expression, suggesting potential therapeutic roles in dental caries prevention. Further research is needed to assess their full impact on S. mutans survival under environmental stresses.PMID:38550660 | PMC:PMC10976999 | DOI:10.1080/20002297.2024.2327758 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - March 29, 2024 Category: Microbiology Authors: Marta Picolo Abish Stephen Aylin Baysan Source Type: research
Clinical Efficacy and Mechanism of Vitamin D2 in Treating Hashimoto's Thyroiditis
CONCLUSION: Vitamin D2 may play an immunomodulatory role by regulating the aforementioned immune-related molecules and immune cells, thereby improving its therapeutic effects on HT.PMID:38410421 | PMC:PMC10896103 | DOI:10.2147/JIR.S441120 (Source: Cell Research)
Source: Cell Research - February 27, 2024 Category: Cytology Authors: Lu Gan Yuqi Li Source Type: research
Clinical Efficacy and Mechanism of Vitamin D2 in Treating Hashimoto ’s Thyroiditis
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - February 22, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging
Int Immunopharmacol. 2023 Dec 15;127:111357. doi: 10.1016/j.intimp.2023.111357. Online ahead of print.ABSTRACTProlonged or excessive ultraviolet (UV) exposure can lead to premature skin aging. Doxercalciferol (Dox), an analog of vitamin D2, is chiefly used to treat endocrine diseases, cardiovascular diseases, kidney diseases, etc. To date, research on Dox in alleviating photoaging and UV-induced inflammation is scarce. In this research, we evaluated the function of Dox in ultraviolet radiation B (UVB)-induced photoaging and explored the potential mechanism in human keratinocytes (Hacat) and BALB/c mice. First, we establish...
Source: International Immunopharmacology - December 17, 2023 Category: Allergy & Immunology Authors: Yuchen Ge Man Li Shirui Bai Cui Chen Shulin Zhang Jiamao Cheng Xiaobo Wang Source Type: research
Doxercalciferol alleviates UVB-induced HaCaT cell senescence and skin photoaging
Int Immunopharmacol. 2023 Dec 15;127:111357. doi: 10.1016/j.intimp.2023.111357. Online ahead of print.ABSTRACTProlonged or excessive ultraviolet (UV) exposure can lead to premature skin aging. Doxercalciferol (Dox), an analog of vitamin D2, is chiefly used to treat endocrine diseases, cardiovascular diseases, kidney diseases, etc. To date, research on Dox in alleviating photoaging and UV-induced inflammation is scarce. In this research, we evaluated the function of Dox in ultraviolet radiation B (UVB)-induced photoaging and explored the potential mechanism in human keratinocytes (Hacat) and BALB/c mice. First, we establish...
Source: International Immunopharmacology - December 17, 2023 Category: Allergy & Immunology Authors: Yuchen Ge Man Li Shirui Bai Cui Chen Shulin Zhang Jiamao Cheng Xiaobo Wang Source Type: research
Gut microbiome and metabolome in aneurysm rat with hypertension after ginsenoside Rb1 treatment
In this study, a rat model was used to investigate the effects of ginsenosides on both blood pressure and intracranial arteries. Comparative analysis was conducted, and 16S rRNA sequencing was employed to identify marker genera within the gut microbiota. Metabolites were also analyzed to uncover potential mediators of blood pressure regulation.Results and Discussion: The results of this study revealed that ginsenosides, particularly ginsenoside Rb1, demonstrated positive effects in reducing both blood pressure and the development of intracranial aneurysms in rats. Furthermore, the analysis of gut microbiota showed that cer...
Source: Frontiers in Pharmacology - November 23, 2023 Category: Drugs & Pharmacology Source Type: research
Efficacy and safety of vitamin D supplementation on psoriasis: A systematic review and meta-analysis
ConclusionsThe efficacy and safety of vitamin D supplementation in the treatment of psoriasis remains unremarkable. The search for a new prognostic index that combines clinical and laboratory factors is needed to compensate for the shortcomings of existing measures and provide stronger evidence of validity. (Source: PLoS One)
Source: PLoS One - November 15, 2023 Category: Biomedical Science Authors: Qianqian Dai Source Type: research
Molecules, Vol. 28, Pages 7516: Nutritional Composition and Odor-Contributing Volatile Compounds of the Edible Mushroom Cantharellus alborufescens
In conclusion, this study supports the use of C. alborufescens as a food rich in fiber and vitamin E, with a suitable amount of protein and other nutrients. (Source: Molecules)
Source: Molecules - November 10, 2023 Category: Chemistry Authors: Mohaddeseh Moghaddam Masoomeh Ghobad-Nejhad Thomas Stegemann Serhat Sezai Çiçek Christian Zidorn Majid Javanmard Tags: Article Source Type: research
Comparison of the effect of daily vitamin D2 and vitamin D3 supplementation on serum 25-hydroxyvitamin D concentration (total 25(OH)D, 25(OH)D2 and 25(OHD3) and importance of body mass index: a systematic review and meta-analysis
CONCLUSIONS: D3 leads to a greater increase of 25(OH)D than D2, even if limited to daily dose studies, but D2 and D3 had similar positive impacts on their corresponding 25(OH)D hydroxylated forms. BMI should be considered when comparing the effect of daily vitamin D2 and vitamin D3 supplementation on total 25(OH)D concentration.STATEMENT OF SIGNIFICANCE: Previous meta-analyses suggest that vitamin D3 may be more potent in increasing serum 25(OH)D concentrations than vitamin D2. In addition, it appeared that with daily dosing this difference is smaller compared to other doses, e.g. monthly/bolus. Our meta-analysis confirms ...
Source: Adv Data - October 21, 2023 Category: Epidemiology Authors: Ellen Ghm van den Heuvel Paul Lips Linda J Schoonmade Susan A Lanham-New Natasja M van Schoor Source Type: research
Comparison of the effect of daily vitamin D2 and vitamin D3 supplementation on serum 25-hydroxyvitamin D concentration (total 25(OH)D, 25(OH)D2 and 25(OHD3) and importance of body mass index: a systematic review and meta-analysis
CONCLUSIONS: D3 leads to a greater increase of 25(OH)D than D2, even if limited to daily dose studies, but D2 and D3 had similar positive impacts on their corresponding 25(OH)D hydroxylated forms. BMI should be considered when comparing the effect of daily vitamin D2 and vitamin D3 supplementation on total 25(OH)D concentration.STATEMENT OF SIGNIFICANCE: Previous meta-analyses suggest that vitamin D3 may be more potent in increasing serum 25(OH)D concentrations than vitamin D2. In addition, it appeared that with daily dosing this difference is smaller compared to other doses, e.g. monthly/bolus. Our meta-analysis confirms ...
Source: Adv Data - October 21, 2023 Category: Epidemiology Authors: Ellen Ghm van den Heuvel Paul Lips Linda J Schoonmade Susan A Lanham-New Natasja M van Schoor Source Type: research
