Vitamin D2 Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Extended-release calcifediol in stage 3-4 chronic kidney disease: a new therapy for the treatment of secondary hyperparathyroidism associated with hypovitaminosis D
This article focuses on the position of extended-release calcifediol in the treatment of patients with stage 3-4 chronic kidney disease and secondary hyperparathyroidism with hypovitaminosis D. Several characteristics of extended-release calcifediol support its use in the intermediate stages of chronic kidney disease. The pharmacokinetics of extended-release calcifediol make it effective for replenishing 25-OH vitamin D levels, with minimal impact on vitamin D catabolism from fibroblast-growth factor-23 and CYP24A1 upregulation. Extended-release calcifediol increases circulating 25-OH vitamin D levels in a dose-dependent m...
Source: Journal of Nephrology - October 9, 2021 Category: Urology & Nephrology Authors: Mario Cozzolino Paola Minghetti Pierluigi Navarra Source Type: research

Improving vitamin D status in bariatric surgery subjects with monthly high-dose ergocalciferol
Conclusion: This study showed 100,000 IUs ergocalciferol once a month is a safe and effective treatment for vitamin D insufficiency in most patients having bariatric surgery.PMID:34521264 | DOI:10.1024/0300-9831/a000728 (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - September 15, 2021 Category: Nutrition Authors: Shannon Galyean David Syn Hadil S Subih Mallory Boylan Source Type: research

Molecules, Vol. 26, Pages 5182: An LC-MS/MS Method for Analysis of Vitamin D Metabolites and C3 Epimers in Mice Serum: Oral Supplementation Compared to UV Irradiation
Conclusions: A validated method, combined with a simple extraction technique, for the sensitive LC-MS/MS determination of vitamin D metabolites is described here. The method can eliminate the interferences in LC-MS/MS analysis caused by the overlapping epimer and isobar due to them having the same molecular weights as 25OHD. The validated method was applied to mouse serum samples. It was concluded that a standard-vitamin D diet causes an increase in the proportion of all the vitamin D metabolites and C3 epimers and isobar, while UV light has no pronounced effect on the concentrations of the majority of the vitamin D metabo...
Source: Molecules - August 26, 2021 Category: Chemistry Authors: Amir Sohail Asma Al Menhali Soleiman Hisaindee Iltaf Shah Tags: Article Source Type: research

Vitamin D supplementation for chronic liver diseases in adults
CONCLUSIONS: Given the high risk of bias and insufficient power of the included trials and the very low certainty of the available evidence, vitamin D supplementation versus placebo or no intervention may increase or reduce all-cause mortality, liver-related mortality, serious adverse events, or non-serious adverse events in adults with chronic liver diseases. There is a lack of data on liver-related morbidity and health-related quality of life. Further evidence on clinically important outcomes analysed in this review is needed.PMID:34431511 | DOI:10.1002/14651858.CD011564.pub3 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 25, 2021 Category: General Medicine Authors: Milica Bjelakovic Dimitrinka Nikolova Goran Bjelakovic Christian Gluud Source Type: research

Vitamin D and Muscle Health: A Systematic Review and Meta ‐analysis of Randomized Placebo‐Controlled Trials
The objective of this study was to investigate the effects of vitamin D supplementation versus placebo on muscle health. For this systematic review and trial-level meta-analysis of placebo-controlled trials, a systematic search of randomized controlled trials published until October 2020 was performed in Medline, Embase, and Google Scholar. We included studies in humans (except athletes) on supplementation with vitamin D2 or D3 versus placebo, regardless of administration form (daily, bolus, and duration) with or without calcium co-supplementation. The predefined endpoints were physical performance reported as timed up and...
Source: Journal of Bone and Mineral Research - August 18, 2021 Category: Orthopaedics Authors: Lise Sofie Bislev, Diana Grove ‐Laugesen, Lars Rejnmark Tags: Original Article Source Type: research