Low intakes of vitamins C and A are associated with obesity in early adulthood.
Authors: Correa-Rodríguez M, Luis Gómez-Urquiza J, Medina-Martínez I, González-Jiménez E, Schmidt-RioValle J, Rueda-Medina B Abstract To evaluate the relationships between the intake of individual antioxidants as well as the dietary antioxidant quality score and obesity-related measures. A cross-sectional study was conducted on 562 young adults. Fat mass, fat-mass percentage, and fat-free mass were measured using a body composition analyzer. The intake of antioxidant nutrients including vitamins C, E, and A, selenium, zinc, and magnesium were calculated based on a 72-hour diet re...
Source: International Journal for Vitamin and Nutrition Research - July 12, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Increased monocyte to HDL cholesterol ratio in vitamin B12 deficiency: is it related to cardiometabolic risk?
In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p 
Source: International Journal for Vitamin and Nutrition Research - July 9, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

High coenzyme Q10 plasma levels improve stress and damage markers in professional soccer players during competition.
Authors: Sánchez-Cuesta A, Cortés-Rodríguez AB, Navas-Enamorado I, Lekue JA, Viar T, Axpe M, Navas P, López-Lluch G Abstract Ubiquinol, the reduced form of Coenzyme Q10 (CoQ10), is a key factor in bioenergetics and antioxidant protection. During competition, professional soccer players suffer from considerable physical stress causing high risk of muscle damage. For athletes, supplementation with several antioxidants, including CoQ10, is widely recommended to avoid oxidative stress and muscle damage. We performed an observational study of plasma parameters associated with CoQ10 levels in...
Source: International Journal for Vitamin and Nutrition Research - July 9, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin D levels are not associated with non-alcoholic fatty liver disease severity in a Brazilian population.
Authors: Dutra JDM, Lisboa QC, Ferolla SM, Carvalho CMML, Mendes CCM, Ferrari TCA, Couto CA Abstract Some epidemiological evidence suggests an inverse correlation between non-alcoholic fatty liver disease (NAFLD) frequency and vitamin D levels. Likewise, a beneficial effect of vitamin D on diabetes mellitus (DM) and insulin resistance has been observed, but this is an unsolved issue. Thus, we aimed to investigate the prevalence of hypovitaminosis D in a NAFLD Brazilian population and its association with disease severity and presence of comorbidities. In a cross-sectional study, the clinical, biochemical and histo...
Source: International Journal for Vitamin and Nutrition Research - July 9, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Chemopreventive activity of Hydroethanolic Murraya koenigii leaves extract (HEMKLE) against chemically induced skin carcinogenesis in mice.
Authors: Kaur S, Dogra S, Sadwal S, Aniqa A Abstract The present study aimed to examine the chemoprotective effect of Hydroethanolic Murraya koenigii leaves extract (HEMKLE) on murine skin carcinogenesis model. For the study, male LACA mice divided into four groups (n = 15 per group). Group I (Control), Group II (DMBA/TPA), Group III (HEMKLE), and Group IV (HEMKLE + DMBA/TPA). Skin tumors were induced in Group II (DMBA/TPA) and Group IV (HEMKLE + DMBA/TPA) by topical application of 7, 12 dimethylbenz[a]anthracene (DMBA) [500 nmol/100 μL of acetone, twice a week ...
Source: International Journal for Vitamin and Nutrition Research - June 27, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.
Authors: Kelishadi R, Heidari-Beni M, Akbarian SA, Hasan Tajadini M, Haghjooy Javanmard S Abstract Background: Genome Wide Association Studies (GWAS) have evaluated several genes related to vitamin D synthesis, metabolism and transport. They have proposed a genetic basis for low levels of vitamin D in the blood. The current study aims to investigate the relationship between certain vitamin D-associated gene variants and vitamin D deficiency in Iranian adolescents. Methods: In this case-control study, the genomic DNA was extracted by Real Time PCR High Resolution Melt (HRM). All measurements were carried out w...
Source: International Journal for Vitamin and Nutrition Research - June 12, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Naringin reduces body weight, plasma lipids and increases adiponectin levels in patients with dyslipidemia.
Authors: Barajas-Vega JL, Raffoul-Orozco AK, Hernandez-Molina D, Ávila-González AE, García-Cobian TA, Rubio-Arellano ED, Ramirez-Lizardo EJ Abstract Naringin is a citrus-flavonoid which has been shown to have positive metabolic and anti-inflammatory effects. For this reason, we believe it would be interesting to study the effects of Naringin administration on body weight, BMI, lipid profile and adiponectin levels in patients with dyslipidemia, especially considering that dyslipidemias along with obesity and subsequent cardiometabolic complications are some of the most important public health i...
Source: International Journal for Vitamin and Nutrition Research - June 11, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Selenium supplementation can relieve the clinical complications of COVID-19 and other similar viral infections.
Authors: Fakhrolmobasheri M, Nasr-Esfahany Z, Khanahmad H, Zeinalian M PMID: 32513070 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - June 11, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Higher dietary phytochemical index is associated with anthropometric indices in children and adolescents: the weight disorders survey of the CASPIAN-IV study.
Authors: Azizi-Soleiman F, Khoshhali M, Heidari-Beni M, Qorbani M, Ali Pourmirzaei M, Kelishadi R Abstract Objectives: The present study aimed to determine the association of total dietary phytochemical intake with generalized and abdominal obesity in children and adolescents. Material and methods: This nationwide cross-sectional study was conducted in 4296 students aged 6-18 years. Dietary phytochemical index (DPI) was calculated as a percentage of daily energy derived from phytochemical-rich foods divided by total daily energy intake. Results: The mean ± standard error of DPIs in the first,...
Source: International Journal for Vitamin and Nutrition Research - May 31, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Children's psychosocial factors of healthy meal preparation as predictors for nutritional status measures.
Authors: Ng CM, Satvinder K, Koo HC, Yap RWK, Mukhtar F Abstract Involving school-age children in the preparation of healthy meals is shown to be associated with positive eating behavior. Yet, it remains unclear whether this can extend to their nutritional status. The present study aimed to determine the association of school-age children's psychosocial factors (knowledge, attitude, practice, self-efficacy) towards healthy meal preparation with their nutritional status (BMI-for-age, waist circumference, body fat percentage). Stratified random sampling was used to select primary schools (n = 8) in Kuala L...
Source: International Journal for Vitamin and Nutrition Research - May 29, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience.
Authors: Pilone V, Tramontano S, Cutolo C, Marchese F, Pagano AM, Di Spirito F, Schiavo L Abstract We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index...
Source: International Journal for Vitamin and Nutrition Research - May 28, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

CD36 gene polymorphism -31118 G   >  A (rs1761667) is associated with overweight and obesity but not with fat preferences in Mexican children.
CD36 gene polymorphism -31118 G > A (rs1761667) is associated with overweight and obesity but not with fat preferences in Mexican children. Int J Vitam Nutr Res. 2020 May 18;:1-9 Authors: Enciso-Ramírez M, Reyes-Castillo Z, Llamas-Covarrubias MA, Guerrero L, López-Espinoza A, Valdés-Miramontes EH Abstract CD36 glycoprotein is a candidate receptor involved in the gustatory detection of lipids and emerging evidence has suggested that genetic variations in CD36 may modulate the oral perception threshold to fatty acids. Here, we analyzed the association of -31118 G &...
Source: International Journal for Vitamin and Nutrition Research - May 19, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Trans-resveratrol supplement lowers lipid peroxidation responses of exercise in male Wistar rats.
This study was designed to examine the effects of all-trans resveratrol supplementation as an antioxidant to mediate anti-oxidation and lipid per-oxidation responses to exercise in male Wistar rats. Sixty-four male Wistar rats were randomly divided into four equal number (n = 16) including training + supplement (TS), training (T), supplement (S) and control (C) group. The rats in TS and S groups received a dose of 10 mg/kg resveratrol per day via gavage. The training groups ran on a rodent treadmill 5 times per week at the speed of 10 m/min for 10 min; the speed gradually increased to 30 ...
Source: International Journal for Vitamin and Nutrition Research - May 15, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Tribulus Terrestris may decrease muscle damage markers following a high-intensity resistance exercise: a pilot study.
In conclusion, short-term supplementation with TT has no effect on IL-6 and hs-CRP, but may be effective on the reduction of muscle damage enzymes CPK and LDH following high-intensity circuit RE. PMID: 32375572 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 9, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage in rats.
Authors: Baykalir BG, Arslan AS, Mutlu SI, Parlak Ak T, Seven I, Seven PT, Yaman M, Gul HF Abstract The aim of this study was to investigate the possible protective effects of chrysin on oxidative status and histological alterations against carbon tetrachloride (CCl4)-induced liver and kidney tissue in rats. The animals were randomly divided into four groups; the control, chrysin (100 mg/kg), CCl4 (0.5 ml/kg) and chrysin + CCl4 groups. Liver and kidney injuries were assessed by biochemical and histopathological examinations. The levels of malondialdehyde (MDA), reduced glutathione (GSH), and su...
Source: International Journal for Vitamin and Nutrition Research - May 2, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Inhibitory effects of bioaccessible anthocyanins and procyanidins from apple, red grape, cinnamon on α-amylase, α-glucosidase and lipase.
Inhibitory effects of bioaccessible anthocyanins and procyanidins from apple, red grape, cinnamon on α-amylase, α-glucosidase and lipase. Int J Vitam Nutr Res. 2020 Apr 24;:1-9 Authors: Ercan P, El SN Abstract The goals of this study were to determine and evaluate the bioaccessibility of total anthocyanin and procyanidin in apple (Amasya, Malus communis), red grape (Papazkarası, Vitis vinifera) and cinnamon (Cassia, Cinnamomum) using an in vitro static digestion system based on human gastrointestinal physiologically relevant conditions. Also, in vitro inhibitory effects of these foods on ...
Source: International Journal for Vitamin and Nutrition Research - April 26, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Fatty acids of human milk - a review.
Authors: Bobiński R, Bobińska J Abstract The composition of human milk is the result of the evolution of mammals over millions of years. Among the most important components of milk are fatty acids. Approximately 85% are saturated and monounsaturated fatty acids - the rest are polyunsaturated one. Their role is to provide energy and immunity and to serve as buildings blocks, as well as assisting the hormonal system and the metabolism of fats, carbohydrates and proteins. The structural differences between fatty acids determine their biodiversity and give them particular physiological importance. Correct developmen...
Source: International Journal for Vitamin and Nutrition Research - April 23, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Prudent and traditional dietary patterns are positively and negatively associated with bone mineral density in Iranian adults, respectively.
In conclusion, the prudent and traditional dietary patterns are positively and negatively associated with BMD in Iranian adults, respectively. PMID: 32319359 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - April 23, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Thiamine pyrophosphate diminishes nitric oxide synthesis in endothelial cells.
Authors: Alcázar-Leyva S, Zapata E, Bernal-Alcántara D, Gorocica P, Alvarado-Vásquez N Abstract Although thiamine pyrophosphate (TPP) is considered a protective agent for endothelial cells, it is still unknown if this is associated with nitric oxide (NO) synthesis. Our aim was to evaluate the synthesis of NO in endothelial cells incubated with TPP and high glucose concentrations. Endothelial cells from the umbilical cord vein from newborns (n = 20), were incubated with 5, 15 or 30 mmol/L glucose, in absence or presence of 0.625 mg/ml of TPP. Our results showed a significant...
Source: International Journal for Vitamin and Nutrition Research - April 3, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin D status among patients with drug-resistant and non-drug-resistant epilepsy.
Authors: Jésus P, Godet B, Darthou-Pouchard L, Fayemendy P, Abdallah-Lebeau F, Villeneuve O, Marcon C, Gimenez L, Preux PM, Couratier P, Desport JC Abstract Background & Aims: Epilepsy affects nearly 70 million people worldwide. Vitamin D deficiency may influence the balance of certain epilepsies. The purpose of this study was to determine the vitamin D status and anthropometric measurements of people with epilepsy (PWE), according to their pharmacosensitivity. Methods: Forty-six PWE, with or without drug resistance, underwent nutritional assessment after giving consent. Weight, body mass index (BMI), t...
Source: International Journal for Vitamin and Nutrition Research - March 14, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

A healthy dietary pattern may be associated with primary insomnia among Iranian adults: A case-control study.
Conclusions: The findings showed that although no statistically significant association was observed between both Western and Iranian traditional dietary patterns with primary insomnia, people with greater adherence to the healthy dietary pattern are less likely to have primary insomnia. PMID: 32156220 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - March 13, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

No effect of vitamin D supplementation on metabolic parameters but on lipids in patients with type 2 diabetes and chronic kidney disease.
Authors: Kim J, Nam JS, Kim H, Lee HS, Lee JE Abstract Background/Aims: Trials on the effects of cholecalciferol supplementation in type 2 diabetes with chronic kidney disease patients were underexplored. Therefore, the aim of this study was to investigate the effects of two different doses of vitamin D supplementation on serum 25-hydroxyvitamin D [25(OH)D] concentrations and metabolic parameters in vitamin D-deficient Korean diabetes patients with chronic kidney disease. Methods: 92 patients completed this study: the placebo group (A, n = 33), the oral cholecalciferol 1,000 IU/day group (B, n ...
Source: International Journal for Vitamin and Nutrition Research - March 10, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Tea catechin role in decreasing the oxidation of dairy beverages containing linseed oil.
Authors: Boroski M, Giroux HJ, Visentainer JV, Dubé P, Desjardins Y, Britten M Abstract Dairy beverages containing emulsified linseed oil is a suitable vehicle for delivering polyunsaturated fatty acids to consumers. However, these beverages are prone to oxidation. The purpose of this study was to evaluate the effect of adding various concentrations (0, 0.001, 0.01 and 0.1% (w/w)) of green tea extract (GTE) to dairy beverages (DB) containing linseed oil (2.0%, w/w), in order to inhibit lipid oxidation during storage at high temperature (50 °C) or under fluorescent light exposure. During storage, th...
Source: International Journal for Vitamin and Nutrition Research - March 7, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Adherence to healthy dietary pattern and risk of kidney disease: a systematic review and meta-analysis of observational studies.
Authors: Soltani S, Jayedi A Abstract Epidemiological studies show that adherence to healthy dietary patterns may be associated with a lower risk of decline in kidney function. However, existing evidence has not been quantitatively gathered. Pertinent observational studies investigating the association of adherence to a healthy dietary pattern, either priori-defined dietary pattern/indices or data-driven dietary patterns, with risk of kidney disease in the general population were identified by searching Medline and Scopus databases to May 28, 2018. A random-effects meta-analysis was applied. The analysis included ...
Source: International Journal for Vitamin and Nutrition Research - March 7, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The association between dietary inflammatory index and risk of central obesity in adults: An updated systematic review and meta-analysis.
Conclusion: The findings proposed that adherence to diets with high DII® scores was associated with increased WC. Further studies with interventional designs are necessary to elucidate the causality inference between DII® and central obesity indices. PMID: 32129728 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - March 6, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin D deficiency and mortality among critically ill surgical patients in an urban Korean hospital.
Authors: Lee JH, Doo SR, Kim D, Park YK, Park EJ, Lee JM Abstract Critically ill patients in intensive care units (ICUs) are exposed to various risk factors for vitamin D deficiency. Vitamin D deficiency in extended-stay patients may result in decreased muscle mass and increased fat tissue, which may impair rehabilitation and recovery. Our study aimed to evaluate the degree of serum vitamin D deficiency in critically ill surgical patients and its association with clinical outcomes. Clinical data from 186 adult male (n = 121; 65.1%) and female (n = 65; 34.9%) patients hospitalized in surgical IC...
Source: International Journal for Vitamin and Nutrition Research - February 26, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

History of tobacco, vitamin D and women.
Authors: Manavi KR, Alston-Mills BP, Thompson MP Abstract Tobacco usage kills more than 8 million people a year. Approximately 7 million of those deaths are the result of direct tobacco use, while approximately 1.2 million are the result of non-smokers being exposed to second-hand smoke. About 200 million of the world's one billion smokers are women and usage among women is increasing in some countries. Nicotine from smoking tobacco, specifically its metabolite cotinine, has negative effects on human health causing lung cancer, COPD and non-respiratory problems. Over a billion people worldwide are Vitamin D defici...
Source: International Journal for Vitamin and Nutrition Research - February 26, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Glycine supplementation during six months does not alter insulin, glucose or triglycerides plasma levels in healthy rats.
In conclusion, chronic supplementation with 1% glycine did not have any significant detrimental side effects in our model. However, more studies are still necessary to evaluate the effect of 1% glycine supplementation in humans. PMID: 32091321 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - February 26, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing.
Authors: Muizzuddin N, Benjamin R Abstract Background: Methylsulfonylmethane (MSM) is an organosulfur compound with known benefits for joint health, sports nutrition, immune function, and anti-aging formulations and is gaining popularity as a nutritional supplement for the support of hair, skin and nails. Methods: The study was conducted in two steps; in Part I (pilot study) a panel of 20 participants ingested either 3 g a day of MSM or placebo capsules for 16 weeks. Visual and subject self assessment of wrinkles and skin texture as the predominant sign of ageing was observed. In Part II (dose-response study)...
Source: International Journal for Vitamin and Nutrition Research - February 23, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Nutritional and environmental contributions to Autism Spectrum Disorders: Focus on nutrigenomics as complementary therapy.
Authors: Jaureguiberry MS, Venturino A Abstract The prevalence of autism spectrum disorders (ASD) has risen sharply in the last 30 years, posing a major public health concern and a big emotional and financial challenge for families. While the underlying causes remain to be fully elucidated, evidence shows moderate genetic heritability contribution, but heavy environmental influence. Over the last decades, modern lifestyle has deeply changed our eating, rest, and exercise habits, while exposure to air, water, and food chemical pollution has increased due to indiscriminate use of pesticides, food additives, adjuvant...
Source: International Journal for Vitamin and Nutrition Research - February 19, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis.
Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease. PMID: 32065560 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - February 19, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin C supplementation had no side effect in non-cancer, but had anticancer properties in ovarian cancer cells.
Authors: Gregoraszczuk EL, Zajda K, Tekla J, Respekta N, Zdybał P, Such A Abstract Vitamin C (Vit C) has been widely used in the treatment and prevention of cancer. Nevertheless, the clinical results are still inconclusive. Using non-cancer (HOSEpiC) and cancer OVCAR-3 cells cultured in basal medium or in ovarian cancer-associated fibroblast (CAF)-supplemented medium, we estimated the dose-dependent effect of Vit C on sodium-ascorbate co-transporters (SVCT1, SVCT2) and glucose transporter (GLUT1) protein expression. Additionally, the action of Vit C on cell proliferation (alamarBlue), membrane permeability (LDH a...
Source: International Journal for Vitamin and Nutrition Research - February 6, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Cocoa and unripe banana flour beverages improve anthropometric and biochemical markers in overweight women: A randomised double-blind study.
The objective of this study was to evaluate the effect of a functional cocoa and unripe banana flour (UBF) beverage intake on the anthropometric and biochemical markers of overweight women. Methods: This prospective, double-blinded, randomized clinical trial involved 60 female volunteers aged between 20 and 50 years. One group received a cocoa beverage (n = 30) and one group received a cocoa and UBF beverage (n = 30), for 6 weeks. The cocoa beverage showed 3.07 total g dietary fiber/serving and 29.55 mg gallic acid equivalentes/portion (GAE/portion). Cocoa and UBF beverage contained 8.48% resi...
Source: International Journal for Vitamin and Nutrition Research - February 6, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

High dietary acid load score is not associated with the risk of metabolic syndrome in Iranian adults.
Conclusion: Our findings suggest no association between dietary acid load and MetS risk in Iranian adults. However, higher dietary acid load, measured by NEAP, but not PRAL, was associated with increased risk of impaired fasting blood sugar. Longitudinal studies are warranted to explore whether a diet low in potential acid load could reduce MetS risk. PMID: 32019435 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - February 6, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Short-term Ubiquinol-10 supplementation alleviates tissue damage in muscle and fatigue caused by strenuous exercise in male distance runners.
Authors: Suzuki Y, Nagato S, Sakuraba K, Morio K, Sawaki K Abstract Background: Coenzyme Q10 (CoQ10) is the electron transporter in oxidative phosphorylation and an endogenous antioxidant. Recent researches have indicated that doses of 200-300 mg/day are needed to recognize effects to prevent oxidative damage in athletes, and the reduced form of CoQ10, ubiquinol-10, is more bioavailable than its oxidized form. Therefore, we hypothesized that higher doses of ubiquinol-10 could elevate plasma CoQ10 levels rapidly and exert physiological benefits in athletes. Therefore, a placebo controlled, double blinded test ...
Source: International Journal for Vitamin and Nutrition Research - February 2, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The alternate-day fasting diet is a more effective approach than a calorie restriction diet on weight loss and hs-CRP levels.
Conclusions: These findings suggest that a modified alternate-day fasting diet can be a beneficial alternative for the management of body weight, fat mass and WC as well as hs-CRP and coagulation factors levels among metabolic syndrome patients. PMID: 32003649 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - February 2, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Dietary total antioxidant capacity and severity of stenosis in patients with coronary artery disease.
Authors: Paknahad Z, Moosavian SP, Jervekani ZT, Hasanzadeh A, Hashemi M Abstract Aim: Coronary artery disease (CAD) is a major cause of mortality worldwide. Many studies suggest that dietary antioxidant can offer significant protection against stroke, heart failure, and coronary heart disease. However, there is no study that assessed the association between dietary TAC and severity of stenosis in patients with CVD. The aim of this study was to investigate the association of dietary TAC and severity of stenosis in patients with coronary artery disease. Methods: Dietary and medical History of 160 patients with CAD ...
Source: International Journal for Vitamin and Nutrition Research - January 29, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Does the normalization of body weight improve male fertility?
Authors: Renck AC, Trarbach EB, Frade Costa EM PMID: 31976827 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - January 26, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

In silico, in-vitro and in vivo screening of biological activities of citral.
The objective of this work was to elucidate the biological properties of citral at molecular level using an integrated in silico, in vitro and in vivo approaches. To elucidate this in silico molecular docking studies were performed with in vitro validation by DPPH scavenging activity, MTT assays, enzymatic assays and Chorio Allantoic Membrane (CAM) assay. The in silico analysis demonstrated the potential binding of citral with PPARγ ligand binding domain and vascular endothelial growth factor receptors (VEGFR-1 and VEGFR-2). Citral is already a proven anti-oxidant which is further confirmed by increased DPPH inhibiti...
Source: International Journal for Vitamin and Nutrition Research - January 24, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Supplemental Vit D3 does not affect musculoskeletal or psychomotor performance in college aged males.
In conclusion, four weeks of Vit D supplementation was not effective in increasing musculoskeletal or psychomotor performance. PMID: 31971089 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - January 24, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Lower serum levels of alpha tocopherol and lycopene is associated with higher pain and physical disability in subjects with primary knee osteoarthritis: A case-control study.
Authors: Eftekharsadat B, Aghamohammadi D, Dolatkhah N, Hashemian M, Salami H Abstract Background: We aimed to determine dietary intake and serum concentration of α-tocopherol and lycopene in subjects with knee osteoarthritis (KOA) in relation to pain intensity and functional status and comparing them with healthy controls. Methods: This case-control study was conducted among 35 patients with primary KOA and 35 matched healthy subjects selected using convenience sampling method. Dietary intakes of alpha-tocopherol and lycopene were estimated from 24-hour dietary records. Visual Analogue Scale (VAS) and Weste...
Source: International Journal for Vitamin and Nutrition Research - January 24, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin D signaling in a mouse allergic sensitization model.
In this study we examined various factors involved in Vitamin D-mediated signalling in a mouse model for allergic dermatitis with systemic (OVA IP) and systemic plus topical allergic sensitization (OVA IP + EC). We found that the major enzyme responsible for 1,25-Vitamin D3 synthesis, the 1-hydoxylase CYP27B1 (3,6-fold for OVA IP and 2,7-fold for OVA IP + EC), the vitamin D receptor (not altered) and the sensitive Vitamin D-mediated signalling target gene CYP24A1 (65-fold in OVA IP and 726-fold in OVA IP + EC) are upregulated after systemic and systemic plus topical allergic sensitization (OVA...
Source: International Journal for Vitamin and Nutrition Research - January 24, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Coenzyme Q10 administration has no effect on sICAM-1 and metabolic parameters of pediatrics with type 1 diabetes mellitus.
Conclusion: Administration of CoQ10 for 3 months in T1DM pediatric patients was well tolerated but had no favorable effect on ED or metabolic parameters. PMID: 31942840 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - January 17, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Reduction of paw edema and liver oxidative stress in carrageenan-induced acute inflammation by Lobaria pulmonaria and Parmelia caperata, lichen species, in mice.
In this study, the anti-inflammatory effect of Lobaria pulmonaria (LP) and Parmelia caperata (PC), two lichen species, was examined in carrageenan-induced mouse paw edema test. Compared to the controls in carrageenan-induced inflammation (n = 5/group), our results showed that pretreatment by single oral doses with PC extract (50-500 mg/kg) gives better results than LP extract (50-500 mg/kg) in terms of anti-edematous activity, as after 4 h of carrageenan subplantar injection, paw edema formation was inhibited at 82-99% by PC while at 35-49% by LP. The higher anti-inflammatory effect of PC, at all d...
Source: International Journal for Vitamin and Nutrition Research - December 20, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Folate and vitamin B-12 deficiencies additively impaired memory function and disturbed the gut microbiota in amyloid- β infused rats.
Folate and vitamin B-12 deficiencies additively impaired memory function and disturbed the gut microbiota in amyloid-β infused rats. Int J Vitam Nutr Res. 2019 Dec 16;:1-13 Authors: Park S, Kang S, Sol Kim D Abstract Folate and vitamin B12(V-B12) deficiencies are associated with metabolic diseases that may impair memory function. We hypothesized that folate and V-B12 may differently alter mild cognitive impairment, glucose metabolism, and inflammation by modulating the gut microbiome in rats with Alzheimer's disease (AD)-like dementia. The hypothesis was examined in hippocampal amyloid-β inf...
Source: International Journal for Vitamin and Nutrition Research - December 18, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Melatonin reduces high levels of lipid peroxidation induced by potassium iodate in porcine thyroid.
Authors: Iwan P, Stepniak J, Karbownik-Lewinska M Abstract Iodine is essential for thyroid hormone synthesis. Under normal iodine supply, calculated physiological iodine concentration in the thyroid is approx. 9 mM. Either potassium iodide (KI) or potassium iodate (KIO3) are used in iodine prophylaxis. KI is confirmed as absolutely safe. KIO3 possesses chemical properties suggesting its potential toxicity. Melatonin (N-acetyl-5-methoxytryptamine) is an effective antioxidant and free radical scavenger. Study aims: to evaluate potential protective effects of melatonin against oxidative damage to membrane lipids...
Source: International Journal for Vitamin and Nutrition Research - December 18, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Calcitriol modulates Cholesteryl ester transfer protein (CETP) levels and lipid profile in hypercholesterolemic male rabbits: A pilot study.
Authors: Radagdam S, Asoudeh-Fard A, Karimi MA, Faridvand Y, Gholinejad Z, Gerayesh Nejad S Abstract Vitamin D3 efficacy against cardiovascular disease prevention has been reported in many experimental studies. We aimed to investigate the effect of the calcitriol or active form of Vitamin D3 (1, 25(OH) 2D3) on serum Cholesteryl ester transfer protein (CETP) levels in a rabbit model of atherosclerosis. New Zealand white male rabbits were fed with 1% cholesterol diet and randomly assigned into two groups (n = 6). The case group was administrated with 50000 calcitriol (IU/kg/per wk) and the control group wh...
Source: International Journal for Vitamin and Nutrition Research - December 18, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Efficacy of phytosomal curcumin among patients with non-alcoholic fatty liver disease.
Authors: Mirhafez SR, Rezai A, Dehabeh M, Nobakht M Gh BF, Bidkhori M, Sahebkar A, Hariri M Abstract Scientists proposed that curcumin could be used for treatment of non-alcoholic fatty liver disease (NAFLD). In this article, we aimed to identify the effect of curcumin on NAFLD improvement. Fifty patients with NAFLD, were divided into two groups in this randomized, double-blind, and controlled clinical trial. Patients in the curcumin group received 250 mg/day of phytosomal curcumin, while those in the control group received 250 mg/day of placebo for duration of eight weeks. Anthropometric measurements an...
Source: International Journal for Vitamin and Nutrition Research - December 11, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

An encapsulated fruit, vegetable and berry juice powder concentrate increases plasma values of specific carotenoids and vitamins.
Authors: Dams S, Holasek S, Tsiountsioura M, Malliga DE, Meier-Allard N, Poncza B, Lackner S, Jansenberger Y, Lamprecht M Abstract Vitamins and carotenoids are organic compounds that are important for vital functions of the human organism. Since the human body is not able to synthesize most of these micronutrients, they need to be supplied by the intake of food or supplements. The aim of this study was to analyze whether a whole food based, encapsulated fruit, berry, and vegetable juice powder concentrate provides bioavailable carotenoids and vitamins A (all-trans retinol), E and C. Eighteen healthy subjects recei...
Source: International Journal for Vitamin and Nutrition Research - November 18, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Optimization the formulation parameters in preparation of α-tocopherol nanodispersions using low-energy solvent displacement technique.
Optimization the formulation parameters in preparation of α-tocopherol nanodispersions using low-energy solvent displacement technique. Int J Vitam Nutr Res. 2019 Nov 14;:1-12 Authors: Jaberi N, Anarjan N, Jafarizadeh-Malmiri H Abstract α-Tocopherol is the main compound of vitamin E with great antioxidant activity. However, like other functional lipid bioactive compounds, it suffers from low bioavailability due to its low water solubility and liable chemical structure. A bottom-up procedure based on a solvent-displacement method was constructed for fabrication of α-tocopherol nanodis...
Source: International Journal for Vitamin and Nutrition Research - November 16, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research