5-Hydroxymethylfurfural and α-ketoglutaric acid supplementation increases oxygen saturation during prolonged exercise in normobaric hypoxia.
5-Hydroxymethylfurfural and α-ketoglutaric acid supplementation increases oxygen saturation during prolonged exercise in normobaric hypoxia. Int J Vitam Nutr Res. 2019 Aug 14;:1-6 Authors: Kössler F, Mair L, Burtscher M, Gatterer H Abstract This double-blinded, randomized and placebo-controlled, crossover study investigated whether α-ketoglutaric-acid (α-KG) and 5-hydroxymethylfurfural (5-HMF) supplementation improves exercise performance in hypoxia and affects physiological responses during the exercise task. Eight moderately trained male participants (age: 25.3 ±&n...
Source: International Journal for Vitamin and Nutrition Research - August 16, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Evidence of a possible therapeutic role of vitamin D in a cohort of adult Caucasian vitiligo patients.
In conclusion, our study provides a novel evidence of a significant positive association of sufficient 25(OH)D levels with the stability of the disease and a satisfactory repigmentation process in Caucasian adult vitiligo patients and strengthen the need to assess vitamin D status in vitiligo. The correlation between sufficient vitamin D levels and a satisfactory course of the disease opens the way for future randomized controlled trials assessing a possible beneficial role of vitamin D supplementation on vitiligo. PMID: 31414974 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin a...
Source: International Journal for Vitamin and Nutrition Research - August 16, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The effects of garlic supplementation on weight loss: A systematic review and meta-analysis of randomized controlled trials.
Authors: Mofrad MD, Rahmani J, Varkaneh HK, Teymouri A, Mousavi SM Abstract Obesity is related to increase in the incidence of morbidity and mortality. Studies have suggested anti-obesity properties of garlic; however, results are inconsistent. This systematic review and meta-analysis is done to summarize the data obtained from available randomized clinical trials on the effect of garlic supplementation on body weight, Body Mass Index (BMI), and Waist Circumference (WC). The online databases of Scopus, PubMed, Google Scholar and Cochrane library were searched until March 2018 for related publications using relevan...
Source: International Journal for Vitamin and Nutrition Research - August 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Effect of the Mediterranean diet in combination with exercise on metabolic syndrome parameters: 1-year randomized controlled trial.
Authors: Pavić E, Hadžiabdić MO, Mucalo I, Martinis I, Romić Ž, Božikov V, Rahelić D Abstract This work aimed to evaluate and compare the benefits of the energy restricted Mediterranean diet (MD) and Standard hypolipemic diet (SHD) accompanied by exercise on metabolic syndrome parameters. A 12-month, randomized, single-blinded, diet-controlled study was conducted on 124 obese participants in the University Hospital Dubrava. Participants were assigned to the MD (n = 63) or the SHD (n = 61) and received the same amount of nutritional education and guidance on physical activity. The complet...
Source: International Journal for Vitamin and Nutrition Research - July 20, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Lycopene enriched tomato extract suppresses chemically induced skin tumorigenesis in mice.
Authors: Koul A, Bansal MP, Chaudhary H, Chugh NA Abstract The present study revealed the effects of Lycopene enriched tomato extract (LycT) on chemically induced skin cancer in mice. Skin tumors were induced by topical application of 7,12-Dimethylbenz(a)anthracene (DMBA) [500 nmol/100 ul of acetone, twice a week for two weeks] and 12-O-tetradecanoyl phorbol-13-acetate (TPA) [1.7 nmol/100 ul of acetone, twice a week for eighteen weeks] and LycT (5 mg/kg b.w.) was administered orally. Male Balb/c mice were divided into four groups (n = 15 per group): control, DMBA/TPA, LycT and Ly...
Source: International Journal for Vitamin and Nutrition Research - July 16, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Magnesium intake and lung cancer risk: A systematic review and meta-analysis.
Authors: Dana N, Karimi R, Mansourian M, Javanmard SH, Laher I, Vaseghi G Abstract Magnesium may reduce the risk of lung cancer by affecting cell proliferation, inflammation and by preserving lung function; however, the results of epidemiological studies on the potential benefits of magnesium in lung pathology are inconclusive. We conducted this meta-analysis to investigate the association between magnesium intake and the risk of lung cancer. A total of 5 studies were extracted from PubMed, SCOPUS, and the Cochrane Review (to May 2018). These studies involved 58,5821 participants with 8,977 lung cancer cases. The ...
Source: International Journal for Vitamin and Nutrition Research - July 16, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Obesity is associated with folate metabolism.
Conclusion: Overweight and obese individuals have lower serum folate concentrations when compared with individuals with normal weight. It is explained by increased use of folic acid, urinary excretion, dilution of blood volume, different levels in different tissues and changes in the endocrine functions of folate. Individuals with higher Body Mass Indexes have less supplement use, unhealthier diets and donot consume sufficient vegetables and fruits, all of which can affect decrease in folate levels. Furthermore, adiposity may affect folate absorption by intestinal epithelium. PMID: 31259666 [PubMed - as supplied by pub...
Source: International Journal for Vitamin and Nutrition Research - July 3, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Zinc deficiency is an independent risk factor for prehypertension in healthy subjects.
Authors: Nevárez-López SC, Simental-Mendía LE, Guerrero-Romero F, Burciaga-Nava JA Abstract Objective: To assess whether zinc deficiency is associated with prehypertension (preHTN) in apparently healthy subjects. Design: Apparently healthy women and men, aged 20 to 60 years were enrolled into a case-control study. Individuals with and without preHTN were allocated into the case and control groups, respectively. Hypertension, liver disease, renal disease, smoking, pregnancy, diabetes, malignancy, hypernatremia, hypomagnesemia, medical treatment, and use of supplements containing zinc were ...
Source: International Journal for Vitamin and Nutrition Research - July 3, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Sorghum Fermented by Aspergillus oryzae NK Enhances Inhibition of Vascular Inflammation in TNF- α-stimulated Human Aortic Smooth Muscle Cells.
Sorghum Fermented by Aspergillus oryzae NK Enhances Inhibition of Vascular Inflammation in TNF-α-stimulated Human Aortic Smooth Muscle Cells. Int J Vitam Nutr Res. 2019 Jun 25;:1-10 Authors: Song HS, Kwon JE, Baek HJ, Kim CW, Jeon H, Ra JS, Lee HK, Kang SC Abstract Sorghum bicolor L. Moench is widely grown all over the world for food and feed. The effects of sorghum extracts on general inflammation have been previously studied, but its anti-vascular inflammatory effects are unknown. Therefore, this study investigated the anti-vascular inflammation effects of sorghum extract (SBE) and ferme...
Source: International Journal for Vitamin and Nutrition Research - June 27, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Higher Oxidative Balance Score Is Associated with Better Glycemic Control among Iranian Adults with Type-2 Diabetes.
Authors: Golmohammadi M, Ayremlou P, Zarrin R Abstract The oxidative balance score (OBS) is a measure of combined pro- and anti-oxidant exposure status, with a higher OBS representing a predominance of anti- over pro-oxidant exposures. We aimed to examine the association of OBS and glycemic control among Iranian adults with type-2 diabetes. This cross-sectional study was conducted among 476 adults with type-2 diabetes (mean age 56.2 y; 66.6% female). Fasting glycosylated hemoglobin (HbA1c) and serum glucose (FSG) levels were measured as markers of glycemic control. The OBS was calculated by combining information f...
Source: International Journal for Vitamin and Nutrition Research - June 26, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

PPAR γ Pro12Ala Polymorphism Influences the Relationship between Dietary Fat Intake, Adiposity and Lipid Profile in Patients with Type 2 Diabetes.
Conclusions: The findings of the current study support a significant association between PPARγ Pro12Ala polymorphism and metabolic syndrome components, and they suggest that this polymorphism can modulate the biological response of dietary fat intake on body mass index and triglyceride levels. PMID: 31188078 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - June 13, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

High Prevalence of Vitamin D Deficiency in Pregnant Women in South China.
This study included 8852 pregnant women and 2000 newborns. The serum 25-hydroxyvitamin D [25(OH)D] levels of the 8852 pregnant women and the cord blood of 2000 newborns were measured. Results: The results showed that the average level of 25(OH)D in pregnant women in this area was 76.55 nmol/L, and women in different trimesters had different vitamin D levels (p 
Source: International Journal for Vitamin and Nutrition Research - June 13, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Inverse relation between fruit and vegetable intake and the risk of gestational diabetes mellitus.
Authors: Mirmiran P, Hosseinpour-Niazi S, Moghaddam-Banaem L, Lamyian M, Goshtasebi A, Azizi F Abstract Background: The aim of this study was to investigate the association of intakes of fruit, vegetable and dairy with gestational diabetes mellitus (GDM). Methods: This prospective study was conducted over a 17 month period, on a random sample of pregnant women (n = 1026), aged 18-45 y, in their first half of pregnancy, attending prenatal clinics in five hospitals' affiliated to universities of medical sciences in different districts of Tehran, Iran. Dietary intakes were assessed during gestational a...
Source: International Journal for Vitamin and Nutrition Research - June 13, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Higher Vitamin B6 Intake is Associated with Lower Depression and Anxiety Risk in Women but not in Men: A large Cross-Sectional Study.
Authors: Kafeshani M, Feizi A, Esmaillzadeh A, Keshteli AH, Afshar H, Roohafza H, Adibi P Abstract Objective: The prevalence of depression and anxiety is increasing worldwide. Diet as a modifiable factor for mental health has received great attention. The aim of the present study was to evaluate the association of vitamin B6 intake with depression and anxiety. Methods: This cross-sectional study was performed among 3362 adults in 2011. Anxiety and depression were evaluated using an Iranian validated version of the Hospital Anxiety and Depression Scale (HADS) questionnaire. Dietary intakes were evaluated by a valid...
Source: International Journal for Vitamin and Nutrition Research - June 13, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The Consumption of Breakfast, Fish and/or Caffeine does not Predict Study Progress in Adult Distance Education.
This study is important as it is the first to report on these relations in this specific age group and educational setting, which is increasingly important due to the increased preference for this type of education. PMID: 31161895 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - June 6, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Effects of Lycopene in Hyperoxia-Induced Lung Injury in Newborn Rats.
Authors: Bastug O, Fatih Sonmez M, Ozturk MA, Korkmaz L, Kesici H, Cilenk KT, Halis H, Korkut S, Ozdemir A, Bastug F, Gunes T, Kurtoglu S Abstract The aim of this study was to evaluate the therapeutic effect of lycopene on a hyperoxia-induced lung injury model in rat pups. Full-term rat pups were included in the study 12-24 h after delivery. The pups were separated into 4 groups: normoxia control (NC), hyperoxia control (HC), hyperoxia + lycopene (HL), and normoxia lycopene (NL). The normoxia groups were housed in ambient air, and the hyperoxia groups in > 85% O2. HL and NL groups recei...
Source: International Journal for Vitamin and Nutrition Research - June 6, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The Protective Effect of Thiamine Pryophosphate Against Sugar-Induced Retinal Neovascularisation in Rats.
Authors: Cinici E, Mammadov R, Findik H, Suleyman B, Cetin N, Calik I, Balta H, Hakki Tas I, Sener E, Altuner D Abstract The aim of this study was to investigate the effect of thiamine pyrophosphate (TPP), administered via sugar water, on retinal neovascularisation in rats. Animals were assigned to three groups, namely the TPP sugar-water group (TPSWG, n = 12), the control group (CG, n = 12) and the healthy group (HG, n = 12). The TPSWG was injected intraperitoneally with TPP once a day for 6 months. CG and HG rats were given distilled water in the same way. TPSWG and CG rats were left free to access an additional...
Source: International Journal for Vitamin and Nutrition Research - June 6, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Antidiabetic and Antioxidant Effects of Apple Cider Vinegar on Normal and Streptozotocin-Induced Diabetic Rats.
In this study, the beneficial effects of apple cider vinegar (ACV) supplementation on blood glucose level, hepatic and renal toxicity and antioxidant enzyme activities in normal and diabetic rats were investigated. Four groups (8 animals/group) of male Wistar rats were used. The animals were fasted overnight and DM was induced by an intraperitoneal injection of freshly prepared streptozotocin (STZ). Control rats were injected with citrate buffer only. ACV was administrated orally for 4 weeks. Our findings indicated that ACV increased the activity of antioxidant enzymes (superoxide dismutase (p
Source: International Journal for Vitamin and Nutrition Research - May 31, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Health Implications of Bioactive Peptides: A Review.
Authors: Nourmohammadi E, Mahoonak AS Abstract Today, due to immobility, improper food habits, and changes in lifestyle, communities are faced with an increase in health problems such as blood pressure, cholesterol, diabetes, and thrombosis. Bioactive peptides are considered as being the main products of protein hydrolysis which exert high effects on the nervous, immune, and gastrointestinal systems. Unlike synthetic drugs, bioactive peptides have no side effects and this advantage has qualified them as an alternative to such drugs. Due to the above-mentioned properties, this paper focuses on the study of health-i...
Source: International Journal for Vitamin and Nutrition Research - May 31, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Alpha Lipoic Acid Reduces Symptoms and Inflammation Biomarkers in Patients with Chronic Hemorrhoidal Illness.
Authors: Šabanović M, Jašić M, Odobašić A, Aleksovska ES, Pavljašević S, Bajraktarević A, Čepo DV Abstract Background: Oral dietary supplementation is becoming increasingly popular as an addition to classical approaches for the prevention and treatment of hemorrhoidal disease. Aim: To examine the effect of orally administrated alpha lipoic acid (ALA), known for its antioxidant and anti-inflammatory properties, in the treatment of patients with permanent symptoms of hemorrhoidal disease. Methods: Patients with second- and third-degree hemorrhoids (n = 100) were enrolled i...
Source: International Journal for Vitamin and Nutrition Research - May 31, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Ascorbic Acid can Reverse the Inhibition of Phytic Acid, Sodium Oxalate and Sodium Silicate on Iron Absorption in Caco-2 cells.
The objective of the present study is to determine the effect of phytic acid (PA), sodium oxalate (SO) and sodium silicate (SS) on non-heme iron bioavailability in both the presence and absence of ascorbic acid (AA) using an in vitro digestion/Caco-2 cell model, and the levels of AA needed to promote Fe absorption from Fe complexed with PA, SO or SS were also determined. The results indicated that adding PA at 1:1, 3:1, 5:1 and 10:1 molar as compared to Fe decreased ferrous iron uptake by 55.80 %(P
Source: International Journal for Vitamin and Nutrition Research - May 29, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin E status in healthy population in Asia: a review of current literature.
Authors: Malik A, Eggersdorfer M, Trilok-Kumar G Abstract Vitamin E is a lipid soluble antioxidant which mainly circulates as α-tocopherol in the human plasma. Its deficiency is associated with ataxia, neuropathy, anaemia and several other health conditions. Although substantial data on vitamin E status has been published worldwide, there is paucity of data on the extent of deficiency from most Asian countries, including India. Part of the problem is lack of validated biomarkers for vitamin E and no consensus on cut offs for defining deficiency and sufficiency. Thus, interpretation of the data on the vitamin...
Source: International Journal for Vitamin and Nutrition Research - May 29, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Cholecalciferol, Ergosterol, and Cholesterol Enhance the Antibiotic Activity of Drugs.
CONCLUSIONS: There is no reported study on the use of cholesterol and ergosterol as modulators of antibiotics or any other drug, making this the first study in this area highlighting the interaction between cholesterol, ergosterol, and cholecalciferol with regard to modifying aminoglycoside activity. PMID: 31124408 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 29, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

No Differences in Hematological Parameters of Fasting and Non-Fasting Pregnant Women Three Months after Ramadan.
Conclusion: Although the immediate effects of Ramadan fasting on hematological parameters are not known, this study concluded that partial fasting during Ramadan from a hematological point of view is of no concern for pregnant women 3 months after the end of Ramadan. PMID: 31124419 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 29, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Instant White Rice with Pigmented Giant Embryonic Rice Improves Glucose Metabolism and Inhibits Oxidative Stress in High-Fat Diet-Fed Mice.
Authors: Im Chung S, W Rico C, Chul Lee S, Young Kang M Abstract The effects of instant cooked rice made from a combination of white rice and pigmented giant embryonic Keunnunjami rice, in comparison with those of instant regular white or brown rice and instant non-pigmented giant embryonic brown rice, on the glucose metabolism and antioxidant defense status in high-fat diet-fed mice were investigated. 56 male C57BL/6N mice were randomly divided into 7 dietary groups: normal control, high fat (23 %, HF), and HF supplemented with normal white (HF + NW) or brown rice (HF + NB), non-pigmented giant embryonic rice (HF...
Source: International Journal for Vitamin and Nutrition Research - May 29, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Pomegranate juice and extract extended lifespan and reduced intestinal fat deposition in Caenorhabditis elegans.
Authors: Zheng J, Heber D, Wang M, Gao C, Heymsfield SB, Martin RJ, Greenway FL, Finley JW, Burton JH, Johnson WD, Enright FM, Keenan MJ, Li Z Abstract Pomegranate juice with a high content of polyphenols, pomegranate extract, ellagic acid, and urolithin A, have anti-oxidant and anti-obesity effects in humans. Pomegranate juice extends lifespan of Drosophila melanogaster. Caenorhabditis elegans (C. elegans) (n = 6) compared to the control group in each treatment, lifespan was increased by pomegranate juice in wild type (N2, 56 %, P
Source: International Journal for Vitamin and Nutrition Research - May 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin D (FokI) Receptor Gene Polymorphism is associated with Vitamin D Deficiency and Chronic Musculoskeletal Pain. A meta-analysis.
Conclusion: FokI VDR gene polymorphism (FF) plays an important role in the relationship between VDD and CMP. PMID: 31084485 [PubMed] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The discovery of beri-beri and scurvy vitamins - two hundred and two years from its discovery.
Authors: Piro A, Tagarelli A, Quattrone A Abstract The history of the discovery of vitamins was the history of their deficiency disorders. Casimir Funk, the father of vitaminic therapy, studied the interrelationships in the human body of those elements that Christiaan Eijkman demonstrated in animals, particularly birds. In 1911, he designated these factors vitamins (vita = life and amine, a nitrogenous substance essential for life); this name was accepted by the scientific community in 1912. Here, we intend to give an illustrative view on the early days of vitamin research as carried out by Casimir Funk. PMID:...
Source: International Journal for Vitamin and Nutrition Research - May 10, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Oral administration of Lactobacillus casei Shirota can ameliorate the adverse effect of an acute aflatoxin exposure in Sprague Dawley rats.
In conclusion, this experiment indicated that probiotic LsC was able to slightly ameliorate the adverse effect of an acute exposure to AFB1 in rats. However, future studies with longer probiotics treatment or higher probiotics dose is required to confirm these findings. PMID: 31056010 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 7, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Profiling older community-dwellers with hypovitaminosis D: A classification tree analysis.
In conclusion, these easily-recordable measures may be used in clinical routine to identify older community-dwellers for whom vitamin D supplementation should be initiated. PMID: 31056012 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 7, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Effect of Vitamin D Supplementation in Prostate Cancer: A Systematic Review of Randomized Control Trials.
Authors: Petrou S, Mamais I, Lavranos G, Tzanetakou IP, Chrysostomou S Abstract Vitamin D is important in many cellular functions including cell cycling and proliferation, differentiation, and apoptosis. Via the induction of cell cycle arrest and/or apoptosis, vitamin D inhibits normal prostatic epithelial cells growth. Review the evidence of the effect of vitamin D supplementation on prostate cancer (PC) biomarkers and patient survival and assess optimal dosage, formulation and duration. Pubmed, Medline and Ebsco Host databases were systematically searched for relevant literature. 8 Randomized Controlled Trials w...
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Zinc and Manganese of serum were negatively, but Copper positively influenced by Iron elevation in diet of male Wistar rats.
Authors: Zolfaghari A, Gheisari HR, Omidi A, Nazifi S Abstract The purpose of the study was to determine the effect of dietary iron on distribution of zinc, manganese, copper, calcium and magnesium in the body of Wistar rats. Commercial Sangak, an Iranian traditional flat bread was used in this study. It was prepared by additionof yeast and sourdough. Different doses of iron (35, 70, 140, and 210 mg/kg per diet) were added to bread vehicle for 30 days with or without baking soda (250 mg/kg per diet). The concentrations of the above elements were determined by graphite furnace and flame atomic absorption ...
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Tissue Changes in the Development of Fatty Liver by Chronic Ingestion of Sucrose Associated with Obesity and Dyslipidemia in Rats.
Authors: Solano-Silva M, Bazán-de Santillana I, Soto-Rodríguez I, Bautista-Piña C, Alexander-Aguilera A Abstract A diet high in sucrose, which is a common food constituent, induces obesity and non-alcoholic fatty liver (NFLD) caused by high caloric intake; however, it is important to investigate those sequential changes in the hepatic parenchyma related to sugar consumption which are associated to obesity and dyslipidemia. We analyzed the effects of long-term sucrose intake on fatty liver development, by the administration of 30% sucrose in drinking water in healthy Wistar rats during 30 ...
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Cautionary Note About Magnitude of Decline in Neural Tube Birth Defects Following Folic Acid Fortification in the United States.
Authors: Ginsburg HJ, Mendez RV, Haskard-Zolnierek KB PMID: 31038031 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Effect of Coenzyme Q10 Alone and in Combination with Exercise Training on Oxidative Stress Biomarkers in Rats.
Conclusion: The present findings indicate that Q10 supplementation increased the Q10 concentration in blood but not in skeletal muscle tissue. On the other hand, Q10 administration alone and in combination with exercise challenge improved antioxidant enzyme capacity especially in the aged rats. PMID: 31038032 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Short sleep duration is related to kidney-related biomarkers, but not lipid profile and diet quality in diabetic nephropathy patients.
Authors: Onvani S, Najafabadi MM, Haghighatdoost F, Larijani B, Azadbakht L Abstract Objectives: Diabetic nephropathy may adversely influence on sleep duration. The quality of diet may also be affected by both sleep duration and diabetes nephropathy. Therefore, lower diet quality in short sleepers-diabetic nephropathy patients might be related to higher metabolic abnormalities. In the present study, we investigated if sleep duration is related to diet quality indices and biochemical markers in diabetic nephropathy patients. Method: This cross-sectional study was conducted among 237 diabetic nephropathy patients, r...
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Vitamin D ameliorates systolic but not diastolic blood pressure in patients with type 2 diabetes: Results from a meta-analysis of randomized controlled trials.
This study aimed to evaluate the subject through a meta-analysis. A computerized literature search on five databases was performed and randomized controlled trials (RCTs) published until March 2016 were identified. The eligibility criteria for articles to be selected were parallel-group RCTs in which consumption of a kind of vitamin D was compared with placebo in patients with T2D. Un-standardized mean difference and its corresponding 95 % confidence interval (CI) was calculated from the effect sizes by using random effects model. Studies comparing intervention group (received vitamin D) with control group (received p...
Source: International Journal for Vitamin and Nutrition Research - May 1, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Alpha-Tocopherol and contrast-induced nephropathy: a meta-analysis of randomized controlled trials.
Conclusions: Alpha-tocopherol pre-treatment is associated with reduction of incidence of CIN. Its administration deserves to be further explored as a simple and inexpensive tool for CIN prevention. PMID: 31017554 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - April 26, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Neuroprotective and long term potentiation improving effects of vitamin E in juvenile hypothyroid rats.
Authors: Baghcheghi Y, Mansouri S, Beheshti F, Shafei MN, Salmani H, Reisi P, Anaeigoudari A, Bideskan AE, Hosseini M Abstract Protective effects of vitamin E (Vit E) on long term potentiation (LTP) impairment, neuronal apoptosis and increase of nitric oxide (NO) metabolites in the hippocampus of juvenile rats were examined. The rats were grouped (n=13) as: (1) control; (2) hypothyroid (Hypo) and (3) Hypo-Vit E. Propylthiouracil (PTU) was given in drinking water (0.05%) during 6 weeks. Vit E (20 mg/ kg) was daily injected (IP). To evaluate synaptic plasticity, LTP from the CA1 area of the hippocampus followed by h...
Source: International Journal for Vitamin and Nutrition Research - April 26, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Turmeric and chicory seed have beneficial effects on  obesity markers and lipid profile in non-alcoholic fatty liver disease (NAFLD).
Turmeric and chicory seed have beneficial effects on obesity markers and lipid profile in non-alcoholic fatty liver disease (NAFLD). Int J Vitam Nutr Res. 2019 Apr 24;:1-10 Authors: Ghaffari A, Rafraf M, Navekar R, Sepehri B, Asghari-Jafarabadi M, Ghavami SM Abstract In an attempt to investigate new strategies aimed at reducing risk factors of non-alcoholic fatty liver disease (NAFLD), effects of turmeric (Curcuma longa L.) and chicory seed (Cichorium intybus L.) supplementation was evaluated in these patients. In this double-blind, randomized, controlled clinical trial, 92 patients with NAFLD ag...
Source: International Journal for Vitamin and Nutrition Research - April 26, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Erythrocytes Polyunsaturated Fatty Acids Mediate Relationship between Dietary Patterns and Depression.
Conclusion: Based on the results, the type of dietary pattern is related to the risk of depression considering the changes in n-3 and n-6 PUFA as well as the ratio of n-3 to n-6 as the mediator variables. Of course, further studies are required in this area. PMID: 30994404 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - April 19, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The Role of Zinc in Thyroid Hormones Metabolism.
Authors: Severo JS, Morais JBS, de Freitas TEC, Andrade ALP, Feitosa MM, Fontenelle LC, de Oliveira ARS, Cruz KJC, do Nascimento Marreiro D Abstract Thyroid hormones play an important role in body homeostasis by facilitating metabolism of lipids and glucose, regulating metabolic adaptations, responding to changes in energy intake, and controlling thermogenesis. Proper metabolism and action of these hormones requires the participation of various nutrients. Among them is zinc, whose interaction with thyroid hormones is complex. It is known to regulate both the synthesis and mechanism of action of these hormones. In t...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Prevalent Low Thiamine Status Among Adults Living in Seoul Metropolitan Area (South Korea).
Authors: Kim YN, Cho YO Abstract The thiamine status of South Korean people has not been recently reported. Therefore, the aim of this study was to determine thiamine intake and status of Korean adults based on a biochemical index. Three consecutive 24-h food recalls and morning first-urine samples were obtained from 143 healthy adults (65 men and 78 women), aged 20-64 years, living in Seoul metropolitan area, Korea. Daily dietary thiamine intake of men and women was 1.42 ± 0.37 mg and 1.18 ± 0.24 mg, respectively. Only 9.1% of the subjects consumed less total thiami...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Duplicate portion sampling gives the most accurate iron intake estimate: Implications for iron status of female students.
Authors: Ghaseminasab Parizi M, Tangestani H, Rahmdel S, Aqaeinejad R SM, Abdollahzadeh SM, Mazloomi SM Abstract Iron deficiency (ID) is one of the most common nutritional problems in the developing world, affecting primarily women of childbearing age. Poor dietary iron intake is a major reason of ID. Accurate measurement of iron intake is of crucial importance to combat the problem. The daily dietary iron intake of 67 female students aged between 20-30 years (a mean BMI of 21.8±3.4 kg/m2) was evaluated using three assessment methods: atomic absorption spectrometry of 3-day food duplicate samples, and food c...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Effects of Astaxanthin Supplementation on Oxidative Stress.
Authors: Wu D, Xu H, Chen J, Zhang L Abstract A systematic review and meta-analysis was conducted in six databases from 1948 to 2015 to assess the antioxidant activity of astaxanthin in humans. Nine randomized controlled trials were included in the systematic review. Results of meta-analysis revealed a borderline significant antioxidant effect of astaxanthin between the intervention and control groups, with a malondialdehyde-lowering effect for lipid peroxidation ( p = 0.050). However, the data included here are insufficient. When compared with the baseline in intervention groups, the meta-analysis suggested that a...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The Effect of Vitamin D on Serum Asymmetric Dimethylarginine in Patients with Mild to Moderate Ulcerative Colitis.
CONCLUSIONS: In this study, we found no significant changes in serum ADMA levels 3 months following a high dose vitamin D administration in mild to moderate UC patients. Further studies in vitamin D deficient patients are needed. PMID: 30982443 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Associations among serum folate, waist-to-hip ratio, lipid profile, and eating habits with homocysteine in an elderly Thai population.
Authors: Paratthakonkun C, Kaewprasert S, Arthan D, Soonthornworasiri N, Tungtrongchitr R, Prangthip P, Wongsutthilerd A, Pooudoung S, Chantaranipapong Y, Nakosiri W, Aroonnual A, Chupeerach C, Chanchai S, Nana A Abstract A lower serum folate level is common in older populations and is associated with increased serum homocysteine concentration. In turn, an elevated homocysteine level is associated with increased risk of cardiovascular disease and age-related diseases. Contemporary studies of folate and dietary risk factors for cardiovascular disease among the elderly population in Thailand are lacking. This cross-s...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

The Effect of L-Arginine Supplementation on Obesity-Related Indices: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Authors: Mousavi SM, Milajerdi A, Fatahi S, Rahmani J, Zarezadeh M, Ghaedi E, Varkaneh HK Abstract The clinical studies regarding the effect of L-arginine in human anthropometry have not been fully consistent, therefore, we carried out a systematic review and meta-analysis of randomized clinical trials in order to precisely evaluate and quantify the efficacy of L-arginine on weight, waist circumference, and BMI. We searched online databases including PubMed, SCOPUS, and Google Scholar for relevant articles up to September 2017. Eligible articles were reviewed by two independent investigators. Mean differences of th...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

No Difference in Magnesium Intake between Obese Women and Healthy Controls.
This study aimed to estimate the dietary intake of magnesium and its association with adiposity parameters in obese women. This cross-sectional study included 125 women, aged between 20 and 50 years, who were divided into two groups: obese group (n = 62) and control group (n = 63). The control group was age-matched. Adiposity parameters determined were weight, body mass index and waist circumference as well as the intake of calories, macronutrients, and magnesium were calculated. The cut-off for obesity was body mass index between 30.0 and 39.9 kg/m2 and for control group was between 18.5 and ...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Synbiotic supplementation is not effective on breast milk selenium concentrations and growth of exclusively breast fed infants: a pilot study.
Authors: Taghipour S, Nikniaz L, Mahavi R, Ostadrahimi A, Nikniaz Z Abstract In this randomized, double-blind, placebo-controlled trial, 57 lactating mothers were randomly allocated into two groups to receive a daily supplement of synbiotic (n = 30) which contained different probiotic strains (2.0 × 108 CFU) and fructooligosaccharide (394 mg) or a placebo (n = 27) for 30 days. Dietary intake was collected from lactating women by 24-hour recall method. Breast milk selenium contents were determined by atomic absorption spectrometry with graphite furnace. Weight for age Z-score (WAZ...
Source: International Journal for Vitamin and Nutrition Research - April 17, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research