Adalimumab Monotherapy in the Treatment of Idiopathic Multifocal Choroiditis: A Case Report
In this study, we report a case of multifocal choroiditis that was successfully treated with adalimumab monotherapy. A 25-year-old male presented with a history of bilateral multifocal choroiditis which was resistant to a combination of azathioprine, valacyclovir, and prednisone. Dilated fundoscopy revealed small creamy-yellow lesions around the arcades in both eyes (OU). Indocyanine green angiography (ICGA) revealed active hypocyanescent lesions around the arcades and macula OU. Valacyclovir was stopped, adalimumab subcutaneous injections biweekly were added to the regimen, and prednisone was tapered after the second adal...
Source: Case Reports in Ophthalmology - November 2, 2022 Category: Opthalmology Source Type: research
Recurrent acute retinal necrosis
Conclusion:
Recurrent ARN can respond to aggressive treatment. Chorioretinal scars, such as from photocoagulation, may be potential sites of viral invasion during recurrences. Antiviral prophylaxis may be indicated for at-risk patients. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - November 1, 2022 Category: Opthalmology Tags: Case Report Source Type: research
Segmental Zoster Paresis of the Unilateral Lower Extremity With Neuritis MRI Findings: A Case Report and Literature Review
We present a 62-year-old male with a HZ rash in the right calf and low back pain radiating to the right leg accompanied by a right leg great toe weakness for one week. Neurological examination revealed 4/5 dorsiflexion of the right great toe. Also, the patient's rash was distributed on the L5 dermatome. The lumbar MRI showed a contrast enhancement of the right L5 nerve root with enlargement diagnosed as neuritis. The patient was treated with valacyclovir. The neuromotor deficit and the cutaneous rash started to improve on the third day of treatment. This case emphasizes the necessity of considering SZP in the differential ...
Source: Herpes - October 24, 2022 Category: Infectious Diseases Authors: Hamisi M Mraja Sule Nur Mraja Inas Mohamed Fawzy Daadour Ayhan Mutlu Selhan Karadereler Meric Enercan Azmi Hamzaoglu Source Type: research
Segmental Zoster Paresis of the Unilateral Lower Extremity With Neuritis MRI Findings: A Case Report and Literature Review
We present a 62-year-old male with a HZ rash in the right calf and low back pain radiating to the right leg accompanied by a right leg great toe weakness for one week. Neurological examination revealed 4/5 dorsiflexion of the right great toe. Also, the patient's rash was distributed on the L5 dermatome. The lumbar MRI showed a contrast enhancement of the right L5 nerve root with enlargement diagnosed as neuritis. The patient was treated with valacyclovir. The neuromotor deficit and the cutaneous rash started to improve on the third day of treatment. This case emphasizes the necessity of considering SZP in the differential ...
Source: Herpes - October 24, 2022 Category: Infectious Diseases Authors: Hamisi M Mraja Sule Nur Mraja Inas Mohamed Fawzy Daadour Ayhan Mutlu Selhan Karadereler Meric Enercan Azmi Hamzaoglu Source Type: research
Successful treatment with repeated dexamethasone implant injections for recurrent macular edema after acute retinal necrosis
ConclusionsThis case shows successful treatment of recurring cystoid macular edema following acute retinal necrosis with repeated intravitreal dexamethasone implants in a patient receiving valacyclovir maintenance treatment. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - October 21, 2022 Category: Opthalmology Source Type: research
Recurrent congenital CMV infection in a sequential pregnancy with severe sequelae, and a possible association with prophylactic valacyclovir treatment: a case report
Cytomegalovirus (CMV) infection occurs in 0.5-2.2% of pregnancies (Ornoy and Diav-Citrin, 2006). The risks for vertical transmission and fetal disease in primary maternal CMV infection are well described (Revello and Gerna, 2002), allowing prenatal counselling. The risks in pregnant women with evidence of preconceptional immunity are far less defined and management is more difficult. An even more complex situation exists in women with a recent primary infection who are planning pregnancy. A widely accepted recommendation is to wait for at least six months from seroconversion to conception (Ornoy and Diav-Citrin, 2006; Reve...
Source: International Journal of Infectious Diseases - October 9, 2022 Category: Infectious Diseases Authors: Tal Brosh-Nissimov, Neta Benshalom-Tirosh, Efrat Bucris, Hagar Morad, Neta S. Zuckerman, Michal Tepperberg Oikawa Tags: Case Report Source Type: research
Recurrent congenital cytomegalovirus infection in a sequential pregnancy with severe sequelae, and a possible association with prophylactic valacyclovir treatment: a case report
Cytomegalovirus (CMV) infection occurs in 0.5-2.2% of pregnancies (Ornoy and Diav-Citrin, 2006). The risks for vertical transmission and fetal disease in primary maternal CMV infection are well described (Revello and Gerna, 2002), allowing prenatal counseling. The risks in pregnant women with evidence of preconception immunity are far less defined, and management is more difficult. An even more complex situation exists in women with a recent primary infection who are planning pregnancy. A widely accepted recommendation is to wait for at least six months from seroconversion to conception (Ornoy and Diav-Citrin, 2006;...
Source: International Journal of Infectious Diseases - October 9, 2022 Category: Infectious Diseases Authors: Tal Brosh-Nissimov, Neta Benshalom-Tirosh, Efrat Bucris, Hagar Morad, Neta S. Zuckerman, Michal Tepperberg Oikawa Tags: Case Report Source Type: research
Valacyclovir-associated neurotoxicity among patients on hemodialysis and peritoneal dialysis: A nationwide population-based study
Front Med (Lausanne). 2022 Sep 20;9:997379. doi: 10.3389/fmed.2022.997379. eCollection 2022.ABSTRACTWhether valacyclovir-associated neurotoxicity (VAN) occurs more frequently in patients with end-stage renal disease (ESRD) on dialysis is unknown. This is the first population-based study to examine the risk of VAN associated with ESRD patients on dialysis. Among 2,284,800 patients diagnosed as having herpes zoster from 2002 to 2016, patients with ESRD on dialysis and individuals with normal renal function were enrolled in this study. Following propensity score matching, we compared the risk of altered mental status between ...
Source: Herpes - October 7, 2022 Category: Infectious Diseases Authors: Yi-Chun Wang Shu-Hui Juan Ching-Hao Li Chu-Lin Chou Li-Ying Chen Li-Nien Chien Te-Chao Fang Source Type: research
Valacyclovir-associated neurotoxicity among patients on hemodialysis and peritoneal dialysis: A nationwide population-based study
Front Med (Lausanne). 2022 Sep 20;9:997379. doi: 10.3389/fmed.2022.997379. eCollection 2022.ABSTRACTWhether valacyclovir-associated neurotoxicity (VAN) occurs more frequently in patients with end-stage renal disease (ESRD) on dialysis is unknown. This is the first population-based study to examine the risk of VAN associated with ESRD patients on dialysis. Among 2,284,800 patients diagnosed as having herpes zoster from 2002 to 2016, patients with ESRD on dialysis and individuals with normal renal function were enrolled in this study. Following propensity score matching, we compared the risk of altered mental status between ...
Source: Herpes - October 7, 2022 Category: Infectious Diseases Authors: Yi-Chun Wang Shu-Hui Juan Ching-Hao Li Chu-Lin Chou Li-Ying Chen Li-Nien Chien Te-Chao Fang Source Type: research
