Unusual Primary Ocular Manifestation of Sarcoidosis
A 23-year-old male patient presented with very mild visual disturbances, but a distinct prominence of the optic discs, more pronounced in the right than in the left eye. The ophthalmic symptoms initially seemed trivial, but a large-scale interdisciplinary workup later identified them as the presenting symptoms of sarcoidosis affecting lung and eyes. A standard steroid monotherapy successfully caused regression of the ophthalmic findings.Case Rep Ophthalmol 2019;10:205 –212 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - July 3, 2019 Category: Opthalmology Source Type: research

Trapped Pre-Macular Bubble of Octafluoropropane Gas Masquerading as Retained Submacular Perfluorocarbon Liquid
Conclusion: Submacular entrapment of various substances used during vitrectomy has been described in a number of case reports and case series. To our knowledge, this is the first described case of a retained fragment of fluorocarbon gas trapped at the macula following successful retinal detachment repair and highlights a previously unreported cause of an abnormal foveal appearance. However, clinical examination together with the use of SD-OCT is helpful in differentiating the appearance from that seen in other retained vitrectomy adjuncts.Case Rep Ophthalmol 2019;10:200 –204 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - June 14, 2019 Category: Opthalmology Source Type: research

A Case of Giant Macular Hole Progression after Rupture of a Giant Retinal Pigment Epithelial Detachment
We report a case of giant macular hole progression after rupture of giant retinal pigment epithelial detachment (PED). The patient was a 91-year-old man who had a giant PED in the left eye. He had bilateral hypermetropia (+2.00 dpt), and he had developed posterior vitreous detachment. The PED was 5,800 μm in diameter and 800 μm in height and ruptured during follow-up. A macular hole was formed, with a diameter of 400 μm, and the height of the PED had reduced to 360 μm. After 5 months, the macular hole expanded up to a diameter of 600 μm. Therefore, some cases of giant PED may lead to macular hole.Case Rep Op...
Source: Case Reports in Ophthalmology - June 6, 2019 Category: Opthalmology Source Type: research

Recovery of Vision following Enzyme Replacement Therapy in a Patient with Mucopolysaccharidosis Type II, Hunter Syndrome
We analyzed the effects of enzyme replacement therapy (ERT) on the visual acuity and visual fields of a patient with mucopolysaccharidosis type II, Hunter syndrome, with degeneration of the retina and abnormalities of the optic nerve. After the ERT, there was an improvement of the visual acuity and visual fields and an improvement of the activities of daily living. Despite the late onset of Hunter syndrome in this patient, ERT was still able to improve the visual function. We conclude that ERT should be considered regardless of the age of the manifestations of the signs and symptoms of Hunter syndrome.Case Rep Ophthalmol 2...
Source: Case Reports in Ophthalmology - June 6, 2019 Category: Opthalmology Source Type: research

Refractory Myopic Retinal Detachment and Macular Hole Closure with Autologous Neurosensory Retinal Free Flap
The purpose of this case report is to describe a modified technique involving the use of an autologous neurosensory retinal free flap for closure of a macular hole (MH) during retinal detachment (RD) surgery. A 50-year-old female presented with sudden vision loss (light perception only) and a recurrent myopic RD associated with an MH. An autologous neurosensory retinal free flap was obtained and moved toward the MH. Silicone oil was used as an endotamponade and removed after 6 months. Two months after oil removal visual acuity improved to 20/400 and remained stable thereafter; however, the patient developed central retinal...
Source: Case Reports in Ophthalmology - May 23, 2019 Category: Opthalmology Source Type: research

Angiography and En Face Optical Coherence Tomography Findings in Acute Syphilitic Posterior Placoid Chorioretinopathy
We report the outer retinal findings on en face optical coherence tomography (OCT) and the alteration of choriocapillaris flow findings on OCT angiography in a patient with ASPPC at the time of presentation, after penicillin treatment completion and during follow-up.Case Rep Ophthalmol 2019;10:165 –171 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - May 23, 2019 Category: Opthalmology Source Type: research

Management of Traumatic Lower-Eyelid Avulsion and Complete Loss of the Lacrimal Canaliculus: A Case Report
Eyelid injuries commonly occur as a result of blunt or sharp periocular trauma. When the medial canthal region is affected, injury can be associated with canalicular laceration or avulsion. Complete loss of the lacrimal canaliculus associated with epiphora is a challenging condition, and reconstruction often leads to poor and disappointing results. Surgical treatment of a patient following blunt facial trauma that resulted in medial avulsion of the lower eyelid with tissue loss is presented. A 72-year-old male patient presented with avulsion of the medial 2/3 of the left lower eyelid together with complete loss of the infe...
Source: Case Reports in Ophthalmology - May 23, 2019 Category: Opthalmology Source Type: research

Muir-Torre Syndrome: The Importance of a Detailed Family History
We describe a case that highlights the importance of a detailed family history.Case Rep Ophthalmol 2019;10:180 –185 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - May 23, 2019 Category: Opthalmology Source Type: research

A Subcutaneous Juvenile Xanthogranuloma in a 4-Year-Old Girl Who Presented with a Lower Eyelid Mass
Juvenile xanthogranuloma (JXG) is a relatively uncommon, benign, histiocytic proliferative cutaneous disorder that typically affects children, with the head and neck being the most common sites. The present case report describes an isolated subcutaneous JXG in a 4-year-old girl who presented with a circumscribed oval mass located in the lower eyelid of the right eye. This lesion was histologically diagnosed as JXG after a surgical resection of the mass.Case Rep Ophthalmol 2019;10:153 –159 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - May 16, 2019 Category: Opthalmology Source Type: research

Relentless Placoid Chorioretinitis: A Case Series of Successful Tapering of Systemic Immunosuppressants Achieved with Adalimumab
Conclusions: In the current two RPC cases, adalimumab was quite effective and useful to reduce the dosages of systemic immunosuppressants. Further study is necessary to confirm the effectiveness of adalimumab in RPC patients.Case Rep Ophthalmol 2019;10:145 –152 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - May 5, 2019 Category: Opthalmology Source Type: research

A Case of Tacrolimus-Induced Posterior Reversible Encephalopathy Syndrome Initially Presenting as a Bilateral Optic Neuropathy
Conclusion: Tacrolimus may be associated with optic neuropathy and PRES at the initial presentation to an ophthalmologist.Case Rep Ophthalmol 2019;10:140 –144 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - April 24, 2019 Category: Opthalmology Source Type: research

Posterior Scleritis in Familial Mediterranean Fever
Conclusions: FMF rarely involves the posterior pole. Visual loss in FMF results from either posterior scleritis or posterior uveitis. A high degree of suspicion of posterior scleritis is warranted in female patients with known FMF presenting with cloudy serous macular detachment.Case Rep Ophthalmol 2019;10:134 –139 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - April 18, 2019 Category: Opthalmology Source Type: research

< b > < i > Exserohilum rostratum < /i > < /b > Keratitis in a Patient with Human Immunodeficiency Virus
Conclusions: Corneal phaeohyphomycosis caused byExserohilumwas noted in an immunocompromised patient with ocular trauma. A brown pigmented lesion in an otherwise white infiltrate due toExserohilumwas diagnosed with corneal scrapings and polymerase chain reaction. Antifungal medications and debridement were the mainstay of corneal fungal infection treatment.Case Rep Ophthalmol 2019;10:127 –133 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - April 17, 2019 Category: Opthalmology Source Type: research

Immunoglobulin Heavy Chain Gene Rearrangement Studies in the Diagnosis of a Paediatric Conjunctival Lesion
We present a case whereby standard immunohistochemistry and flow cytometry studies for a conjunctival biopsy were unable to reliably differentiate between the two distinct pathological processes of benign reactive lymphoid hyperplasia from conjunctival lymphoma. A tissue diagnosis was only able to be conclusively attained after the application of immunoglobulin heavy chain rearrangement studies to the specimen. This is unusual and to our knowledge has not been previously expressed in the literature. Hence, the use of these further molecular studies may have great potential clinical implications in helping resolve such diag...
Source: Case Reports in Ophthalmology - April 15, 2019 Category: Opthalmology Source Type: research

Temporary Filtering Bleb Failure Induced by Anterior Chamber Sulfur Hexafluoride Gas: A Complication after Descemet Membrane Endothelial Keratoplasty
Herein, we report two clinical cases with acute temporary filtering bleb obstruction by gas tamponade after Descemet membrane endothelial keratoplasty (DMEK) surgery and postoperative intraocular pressure (IOP) peaks. Both patients underwent uncomplicated DMEK surgery with 20% sulfur hexafluoride (SF6) anterior chamber tamponade and had previous trabeculectomy for glaucoma. Prior to surgery, both patients showed patent bleb function with low to normal IOP without antiglaucomatous medication. After uneventful DMEK surgery, both patients showed postoperative IOP peaks of up to 50 mm Hg despite patent inferior iridotomy and n...
Source: Case Reports in Ophthalmology - April 15, 2019 Category: Opthalmology Source Type: research

Corneal Perforation after Nd:YAG Capsulotomy: A Case Report and Literature Review
Conclusion: The possibility of corneal perforation after Nd-YAG capsulotomy in patients with systemic scleroderma and connective tissue disease should be borne in mind when treating such patients.Case Rep Ophthalmol 2019;10:111 –115 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - April 3, 2019 Category: Opthalmology Source Type: research

Erratum
Case Rep Ophthalmol 2019;10:110 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - March 31, 2019 Category: Opthalmology Source Type: research

Evaluation of a Novel Blue-Colored Ophthalmic Viscoelastic Device Applied during Phacoemulsification in Eyes with Pseudoexfoliation Syndrome
The objective of this case series is to investigate whether the use of a blue-colored OVD during cataract surgery in patients with pseudoexfoliation syndrome (PXF) and narrow pupils (miosis) has advantages over the use of a clear standard OVD in combination with trypan blue. We included 52 eyes of 52 consecutive cataract patients diagnosed with PXF. Study participants were divided into two groups of 26 patients each, depending on which OVD was used during surgery (group A: blu e-colored OVD; group B: standard clear OVD). Intraoperatively, we evaluated the operation time (surgery start to the beginning of phacoemulsificatio...
Source: Case Reports in Ophthalmology - March 21, 2019 Category: Opthalmology Source Type: research

Combined Single-Step Procedure for Correction of Silent Sinus Syndrome
We present a 30-year-old man who noticed facial asymmetry during the previous month and was referred to our oculoplastic clinic. His examination revealed right hypoglobus and a 2-mm right enophthalmos. The diagnosis of right SSS was confirmed by orbital and paranasal computed tomography scan. The patient had no otolaryngological symptoms and visual acuity was normal bilaterally. He was treated surgically in a combined approach by a team of oculoplastic and otorhinolaryngology surgeons. Functional endoscopic sinus surgery included uncinectomy, maxillary antrostomy, and orbitotomy, with insertion of an orbital implant. This ...
Source: Case Reports in Ophthalmology - March 20, 2019 Category: Opthalmology Source Type: research

A Case of Eosinophilic Chronic Rhinosinusitis Associated with Choroidal Folds and Ocular Motility Disorder
We report a case of eosinophilic chronic rhinosinusitis (ECRS) associated with choroidal folds and ocular motility disorder. A 50-year-old male with rhinosinusitis and bronchial asthma presented with anorthopia of the lower visual field and ocular motility disorder of the left eye. Dilated fundus examination and optical coherence tomography (OCT) revealed wavy choroidal folds in the upper retina. An emergent computed tomography (CT) showed sinusitis, a partial defect of the superior wall of the orbit on the left side, and deformation of the left eye. Based on the clinical findings, the patient was diagnosed with sinusitis ...
Source: Case Reports in Ophthalmology - March 7, 2019 Category: Opthalmology Source Type: research

Bilateral Syphilitic Optic Neuropathy with Secondary Autoimmune Optic Neuropathy and Poor Visual Outcome
We describe the case of a 65-year-old man who suffered progressive visual loss despite appropriate treatment of ocular syphilis. Our patient initially presented with a unilateral 6th nerve palsy and associated double vision, which self-resolved over 6 months. His ophthalmic examination was otherwise normal. 12 months after the initial complaint, he represented with dyschromatopsia, reduced visual acuity, tonic pupils, and optic nerve atrophy. He tested positive for syphilis and was admitted for treatment of neurosyphilis with high-dose benzylpenicillin. Despite treatment, at a 4-month review his visual acuity remained poor...
Source: Case Reports in Ophthalmology - February 26, 2019 Category: Opthalmology Source Type: research

Rare Histological Type of Adenoma of the Nonpigmented Ciliary Epithelium
We report the rare case of an adenoma of the nonpigmented ciliary epithelium (NPCE). A 67-year-old healthy man presented with a regularly shaped and nonpigmented mass at the iris root of his right eye. His best-corrected visual acuity was 1.5 with normal intraocular pressure. During observation, the size of the tumor remained stable for 1.5 years but then rapidly grew, extending through the iris, and gradually enlarged to the point of compressing the iris. Ultimately, an iridocyclectomy with scleral resection under a lamellar scleral flap was performed. The histopathologic features of the resected tissue were consistent wi...
Source: Case Reports in Ophthalmology - February 20, 2019 Category: Opthalmology Source Type: research

Vogt-Koyanagi-Harada Disease-Like Uveitis during Nivolumab (Anti-PD-1 Antibody) Treatment for Metastatic Cutaneous Malignant Melanoma
We report such a case. A 63-year-old woman with metastatic cutaneous malignant melanoma experienced visual loss in both eyes 10 days after her second nivolumab injection. Her decimal best-corrected visual acuity (BCVA) was 0.7 in the right eye and 0.4 in the left eye. Examination revealed bilateral granulomatous keratic precipitates and posterior synechiae in the left eye. Optical coherence tomography showed multiple sites of serous retinal detachment (SRD) in the left eye and wavy retinal pigment epithelium in both eyes. Fluorescein angiography revealed multiple pinpoint-sized areas of leakage in both eyes and active leak...
Source: Case Reports in Ophthalmology - February 8, 2019 Category: Opthalmology Source Type: research

Maxillary Zoster and Neurotrophic Keratitis following Trigeminal Block
We report a case of reactivated maxillary herpes zoster combined with neurotrophic keratitis due to percutaneous 2nd and 3rd branch of trigeminal nerve block with alcohol to treat trigeminal neuralgia. A 57-year-old female came to the ophthalmology department complaining of decreased visual acuity and skin vesicle over the right lower lid and cheek. She had undergone right trigeminal nerve block for treatment of trigeminal neuralgia. Clinical examination revealed neurotrophic keratitis and maxillary herpes zoster. She was treated with oral and topical antivirals and vigorous lubrication with eye drops. Her neurotrophic ker...
Source: Case Reports in Ophthalmology - February 6, 2019 Category: Opthalmology Source Type: research

Intrascleral Fixation of an Intraocular Lens through the Pars Plana Prevents Corneal Endothelial Damage
We report two cases of aphakia in whom an intraocular lens (IOL) was intrasclerally fixated through the pars plana to minimize further corneal endothelial damage. A modified lock-and-lead technique was used. A sclerotomy and scleral incision were made 2.5 mm from the limbus. A 24-G catheter needle was used for penetration of the leading haptic, and two ultrathin 30-G needles were used to bury the ends of the haptics. The scleral incision was sutured with 8-0 nylon. Corneal endothelial cells were preserved after surgery. Neither intra- nor postoperative complications were observed. Intrascleral fixation of an IOL through th...
Source: Case Reports in Ophthalmology - February 4, 2019 Category: Opthalmology Source Type: research

Two-Year Outcome of Aflibercept for the Treatment of Choroidal Neovascularization in Punctate Inner Choroidopathy
Punctate inner choroidopathy (PIC) is a rare inflammatory chorioretinopathy that predominantly affects young myopic women. Visual prognosis is generally good, but occurrence of choroidal neovascularization (CNV) is common and may be vision threatening. Case reports and short case series support the effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) agents (ranibizumab and bevacizumab) for CNV associated with PIC given their anti-angiogenic and anti-inflammatory effects. Evidence concerning aflibercept, a more recent intravitreal anti-VEGF, is limited to a single case report. In this case report, w...
Source: Case Reports in Ophthalmology - January 27, 2019 Category: Opthalmology Source Type: research

Neurosarcoidosis Occurring 6 Years after Onset of Vogt-Koyanagi-Harada Disease
We report a case of the concurrence of VKHD and sarcoidosis, which may share a common pathophysiology. Accumulation of further similar cases is necessary to elucidate the precise mechanism underlying the concurrence of these two diseases.Case Rep Ophthalmol 2019;10:32 –40 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 27, 2019 Category: Opthalmology Source Type: research

Penetrating Eyelid and Ocular Fishhook-Related Injury
Conclusions: The visual prognosis for a fishhook-related ocular injury is associated with various variables including size and location of lacerated wound and technique to remove a fishhook. In this case, a patient could achieve a favorable final visual and anatomical outcome. This removal technique could be taken into consideration when encountering a fishhook-related eye injury patient.Case Rep Ophthalmol 2019;10:41 –46 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 27, 2019 Category: Opthalmology Source Type: research

Intracameral Air and Fibrin Glue for the Management of Late Bleb Leak following Glaucoma Surgery
Conclusion: The combination of intracameral air and fibrin glue may have a role in the management of bleb leaks.Case Rep Ophthalmol 2019;10:47 –52 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 27, 2019 Category: Opthalmology Source Type: research

Different Types of Maculopathy in Eyes after a High-Voltage Electrical Shock Injury
Conclusion: Two different types of maculopathy can occur in each eye after high-voltage electrical shock injury, and this might be due to asymmetric pathogenesis of the eyes according to the proximity to the route of electrical current.Case Rep Ophthalmol 2019;10:19 –23 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 17, 2019 Category: Opthalmology Source Type: research

The Difficulty of Diagnosing Invasive Aspergillosis Initially Manifesting as Optic Neuropathy
Conclusions: When examining refractory and persistent disc swelling, we should rule out fungal infections of the optic nerve.Case Rep Ophthalmol 2019;10:11 –18 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 16, 2019 Category: Opthalmology Source Type: research

An Atypical Presentation of Acute Macular Neuroretinopathy after Non-Ocular Trauma
Conclusion: We report a rare case of AMN following non-ocular trauma with the unique fundus findings of CWS and RH. This presentation supports the role of ischemia in the retinal deep capillary plexus, of which trauma contributed to the pathophysiological process.Summary: AMN is a rare condition whose pathophysiological process remains speculative. We report an atypical case of AMN, which supports the role of trauma in the pathophysiology of deep retinal capillary plexus compromise.Case Rep Ophthalmol 2019;10:1 –4 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 13, 2019 Category: Opthalmology Source Type: research

Impaired Retinal Circulation during Axitinib Treatment for Metastatic Renal Cell Carcinoma
Conclusion: Clinicians should be aware of retinal circulatory disorder that can occur in patients under axitinib treatment.Case Rep Ophthalmol 2019;10:5 –10 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 13, 2019 Category: Opthalmology Source Type: research

Acute-Onset Optic Neuropathy in Wilson ’s Disease
We report the case of a 20-year-old female who presented with acute liver failure and associated monocular vision loss. WD was found to be a cause of her liver disease and decreased vision.Case Rep Ophthalmol 2018;9:520 –525 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 3, 2019 Category: Opthalmology Source Type: research

Diffuse Large B-Cell Lymphoma of the Lacrimal Sac in a Japanese Patient
Conclusion: We report a case of DLBCL in the lacrimal sac, which is the most common type of lacrimal sac lymphoma in Japan. Since DLBCL is one of the aggressive types of lymphoma, Japanese patients with lacrimal sac lymphoma tend to have a poor prognosis.Case Rep Ophthalmol 2018;9:516 –519 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 3, 2019 Category: Opthalmology Source Type: research

Exudative Type 3 Retinal Arteriovenous Malformation in a Pediatric Patient
We describe a 7-year-old girl who developed exudation nasally to the right optic disc due to retinal arteriovenous malformation. Fluorescein angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography were performed. We give an overview of the different imaging techniques and discuss the differential diagnosis. Since there was no visual impairment, no treatment was started. A spontaneous decrease in edema and exudation was noted after 6 months.Case Rep Ophthalmol 2018;9:504 –509 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - December 21, 2018 Category: Opthalmology Source Type: research

A 5-Year-Old Case of Choroidal Neovascularization in Enhanced S-Cone Syndrome Treated with Ranibizumab
Conclusion: CNV has been reported to occur in different inherited retinal degenerations, including ESCS. Our experience confirms that treatment with ranibizumab in patients with CNV-complicated ESCS can be potentially vision-saving.Case Rep Ophthalmol 2018;9:510 –515 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - December 21, 2018 Category: Opthalmology Source Type: research

Successful Certolizumab Pegol Treatment of Chronic Anterior Uveitis Associated with Psoriasis Vulgaris
This report presents details on a 45-year-old male Japanese patient with chronic and refractory anterior uveitis associated with psoriasis vulgaris who was administered certolizumab pegol (CZP), which is an anti-tumor necrosis factor alpha (TNF- α) monoclonal antibody. Although CZP has only been formally approved for rheumatoid arthritis treatment in Japan, a clinical trial allowed us to assess CZP effectiveness in this patient. The grade 3+ anterior chamber inflammation (for both the cells and flare) observed at baseline improved to grade 0 at 3 months post-treatment. Dermatologically, the psoriasis area severity in...
Source: Case Reports in Ophthalmology - December 14, 2018 Category: Opthalmology Source Type: research

Ocular Complications from Retained Intraocular Ointment Discovered 33 Months after Cataract Surgery
We present a case of a patient who presented with history of poor vision since the time of cataract surgery 33 months prior, who had cystoid macular edema, reduced endothelial cell count, and apparent Maxitrol ointment (neomycin, polymyxin B sulfate, and dexamethasone in paraffin vehicle; Novartis Pharmaceuticals UK) floating in the AC. The patient was treated with AC washout and sub-Tenon injection of triamcinolone. His vision, retinal architecture by optical coherence tomography, endothelial cell count, and pachymetry has been followed for 9 months following this treatment.Case Rep Ophthalmol 2018;9:493 –498 (Sourc...
Source: Case Reports in Ophthalmology - December 13, 2018 Category: Opthalmology Source Type: research

Postoperative Late-Onset Endophthalmitis Caused by < b > < i > Leishmania donovani < /i > < /b > : A Case Report
Leishmania donovani is a human blood parasite that belongs to the genusLeishmania. We would like to present a case of lateLeishmania donovani endophthalmitis in one eye of a patient that underwent simultaneous bilateral grade 3 cataract surgery.Case Rep Ophthalmol 2018;9:484 –486 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - December 4, 2018 Category: Opthalmology Source Type: research

Multimodal Imaging in a Case of Idiopathic Neuroretinitis
A 37-year-old woman presented with painful visual loss in the left eye for 2 weeks. The best-corrected visual acuity was 20/200. Ophthalmic examination of the left eye revealed vitreous cells, optic disc swelling, serous retinal detachment, and macular star-figure hard exudates. Swept-source optical coherence tomography showed both inner and outer retinas were swollen, the choroid was thickened, and the corresponding retinal pigment epithelium was elevated. Wide-field indocyanine green angiography disclosed multiple hypofluorescent spots in the mid-periphery. Taken together, an involvement of optic disc, entire retina, and...
Source: Case Reports in Ophthalmology - December 4, 2018 Category: Opthalmology Source Type: research

Corneal Toxicity Induced by ABT-414 Therapy for Glioblastoma Multiforme: A Case Report
Conclusions: The systemic use of EGFR inhibitor ABT-414 may be associated with corneal toxicity and the effects are reversible with treatment.Case Rep Ophthalmol 2018;9:479 –483 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - November 29, 2018 Category: Opthalmology Source Type: research

Microvascular Capillary Plexus Findings of Commotio Retinae on Optical Coherence Tomography Angiography
We present a 46-year-old man who sustained a tennis ball injury to the right eye with visual acuity reduction to 20/30 and grey-white deep macular discoloration, suggestive of CR. Spectral-domain OCT (SD-OCT) showed increased reflectivity and thickness of the ellipsoid zone (junction of photoreceptor inner and outer segments). OCTA revealed no apparent microvascular alterations (right versus left eye) in the foveal avascular zone superficial (0.42 vs. 0.43 mm2) and deep (0.45 vs. 0.44 mm2), superficial foveal capillary density (34.1 vs. 32.6%), and superficial parafoveal capillary density (55.2 vs. 52.2%). Deep macular cap...
Source: Case Reports in Ophthalmology - November 27, 2018 Category: Opthalmology Source Type: research

Off-Label Use of Phakic Intraocular Lens with a “Piggyback” Technique
Conclusion: This case demonstrates the successful off-label use of a phakic IOL in a pseudophakic, highly myopic patient with a piggyback technique, resulting in improved visual acuity and ultimately allowing IOL placement in the fellow eye for emmetropia. This off-label use of pIOL can offer ophthalmologists an alternative option for pseudophakic patents with severe refractive error.Case Rep Ophthalmol 2018;9:465 –472 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - November 22, 2018 Category: Opthalmology Source Type: research

Diagnosis, Clinical Trend, and Treatment of Diffuse Lamellar Keratitis after Femtosecond Laser-Assisted in situ Keratomileusis: A Case Report
We report a severe case of diffuse lamellar keratitis (DLK) following femtosecond laser-assisted in situ keratomileusis (femto-LASIK). A 25-year-old man was submitted to 150 kHz iFS ® IntraLase-assisted LASIK in both eyes for compound myopic astigmatism. The day after surgery, clinical examination showed a diffuse whitish granular cell reaction particularly in the right eye. High-dose dexamethasone eyedrops with topical antibiotic and artificial tears were prescribed. Five day s after surgery, a central corneal opacity with convergent striae was detected at biomicroscopy. The suspicion of DLK was confirmed. Additional ...
Source: Case Reports in Ophthalmology - November 14, 2018 Category: Opthalmology Source Type: research

Iris Morphological Features in Patients with 360 ° Angle-Closure Neovascular Glaucoma: An Anterior Segment Optical Coherence Tomography Study
Conclusions: In patients with 360 ° angle-closure NVG, the iris thickness decreased to about 50% of that in healthy subjects, and the PAS length exceeded the trabecular meshwork length by about 1.5 times.Case Rep Ophthalmol 2018;9:449 –456 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - October 25, 2018 Category: Opthalmology Source Type: research

Detection of < b > < i > Candida < /i > < /b > Endophthalmitis in a Newborn Using Handheld Spectral-Domain Optical Coherence Tomography
In a newborn with candidemia, two retinal lesions were seen without external inflammatory signs or reaction in the anterior chamber or vitreous. However, handheld spectral domain-optical coherence tomography (HH SD-OCT) images show that one of the retinal lesions had a “firework display” projecting to the vitreous that was not identified in indirect ophthalmoscopy. This finding suggested aCandida endophthalmitis. HH SD-OCT findings allowed us to make an accurate diagnosis and, therefore, modified the decision-making process in the treatment of the pathology.Case Rep Ophthalmol 2018;9:439 –443 (Source: Cas...
Source: Case Reports in Ophthalmology - October 18, 2018 Category: Opthalmology Source Type: research

Bilateral Spontaneous Hyphemas in a Patient with Aplastic Anemia
We present a patient with aplastic anemia without obvious risk factors for hyphema who developed bilateral spontaneous hyphemas. To our knowledge, this is the first reported case of bilateral spontaneous hyphemas in a patient with aplastic anemia.Case Rep Ophthalmol 2018;9:444 –448 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - October 18, 2018 Category: Opthalmology Source Type: research

Development of a Donor Tissue Holding Technique for Descemet ’s Membrane Endothelial Keratoplasty Using a 25-Gauge Graft Manipulator
Conclusions: This donor tissue holding technique enabled rapid and safe DMEK in a reproducible manner, even in Asian eyes with shallow anterior chambers with high vitreous pressure.Case Rep Ophthalmol 2018;9:431 –438 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - October 11, 2018 Category: Opthalmology Source Type: research

Lipemia Retinalis, Macular Edema, and Vision Loss in a Diabetic Patient with a History of Type IV Hypertriglyceridemia and Pancreatitis
Conclusions: In the setting of lipemia retinalis and hypertriglyceridemia, the current patient developed macular edema and vision loss. The macular edema was treated with intravitreal injections of bevacizumab, and the patient experienced a rapid recovery of visual acuity.Case Rep Ophthalmol 2018;9:425 –430 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - October 5, 2018 Category: Opthalmology Source Type: research