Spontaneous Corneal Graft Reattachment Following Descemet Stripping Automated Endothelial Keratoplasty in Prone Position: A Case Report and Literature Review
Graft detachment after Descemet stripping automated endothelial keratoplasty (DSAEK) is usually managed with air-bubbling. However, it is an invasive procedure, which can cause corneal endothelial reduction, and requires hospitalization and supine position maintenance. Only few case reports on graft reattachment in the prone position exist, and this is the first report from Japan. An 87-year-old woman presented with sudden pain in her left eye. Examination of her left eye showed a best-corrected vision of 20/50, shallow anterior chamber, cataractous lens, central corneal thickness (CCT) of 630 μm, and corneal endothelial ...
Source: Case Reports in Ophthalmology - February 14, 2022 Category: Opthalmology Source Type: research

Very High-Frequency Ultrasonography Signs in Bilateral Acute Choroidal Effusion Associated with Systemic Sulphonamide Medications: 2 Cases
Sulphonamides are commonly used in medicine for several purposes; however, they can lead to significant adverse effects, including idiosyncratic reactions and choroidal detachment corresponding to a forward rotation of the iris-lens diaphragm; this could also evolve into acute transient myopia with possible acute angle closure glaucoma. The risk of such reactions to sulphonamides is approximately 3%. In our communication, we have reported on 2 cases involving patients who suffered choroidal detachments after starting sulphonamide treatments and who were diagnosed with the help of ultrasound biomicroscopy. Patient 1 was an ...
Source: Case Reports in Ophthalmology - February 14, 2022 Category: Opthalmology Source Type: research

Reversible Retinopathy Associated with Fibroblast Growth Factor Receptor Inhibitor
We present a case of reversible, pseudovitelliform lesions while a patient was taking pembrolizumab (PDL-1 inhibitor) and erdafitinib (pan-fibroblast growth factor receptor inhibitor) outside of clinical trial protocols. A 61-year-old patient with 3 days of metamorphopsia was found to have pseudovitelliform lesions in both eyes 6 weeks after initiation of erdafitinib. After discontinuation of this drug, his visual complaints resolved and his lesions decreased on optical coherence tomography. To our knowledge, this is the first case depicting reversible macular lesions with use of this newly approved medication outside of c...
Source: Case Reports in Ophthalmology - February 11, 2022 Category: Opthalmology Source Type: research

A Case of an Intraorbital Wooden Chip Foreign Body Diagnosed and Removed Several Months after Injury Despite Repeated Imaging Study
Intraorbital foreign bodies due to trauma are commonly encountered in clinical practice. However, organic foreign bodies, such as wood chips, can sometimes be difficult to diagnose. Here, we report the case of a patient with a wooden chip located intraorbitally that was not detected until spontaneous discharge, despite repeated diagnostic imaging. A 43-year-old intoxicated woman presented to our hospital with a bruised face and eyelid. The patient was diagnosed with conjunctivitis and iritis, but no foreign body was noted in repeated imaging studies since the first visit. Therefore, the patient was observed and managed con...
Source: Case Reports in Ophthalmology - February 10, 2022 Category: Opthalmology Source Type: research

Monocular Temporal Hemianopia due to Acute Zonal Occult Outer Retinopathy
We report a case of a young woman with a monocular temporal hemianopia respecting the vertical meridian due to acute zonal occult outer retinopathy (AZOOR). This 34-year-old woman presented with a 10-day history of left eye vision loss and was found to have a visual acuity of 20/20 in both eyes, a left RAPD, and left temporal hemianopia on Humphrey 24-2 SITA-Fast visual field testing. Dilated fundus examination showed a normal-appearing optic nerve and retina in both eyes. She had already had a normal magnetic resonance imaging of the orbits with contrast and retinal disease was suspected. Optical coherence tomography show...
Source: Case Reports in Ophthalmology - February 10, 2022 Category: Opthalmology Source Type: research

Simultaneous and Sequential Development of Sixth Nerve Palsy and Horner ’s Syndrome from Carotid Cavernous Sinus Fistulas
The combination of ipsilateral sixth nerve palsy (6NP) and Horner ’s syndrome (Horner’s) is a localizing sign of an injury to the posterior cavernous sinus. The presentation and clinical course of 3 patients presenting with coexisting ipsilateral 6NP and Horner’s as a result of carotid cavernous sinus fistulas (CCFs) are discussed in this case series. We hig hlight these cases to show the possible sequence of events: (i) simultaneous discovery of 6NP and Horner’s, (ii) 6NP followed by Horner’s, and (iii) Horner’s followed by 6NP. It is important to carefully assess for Horner’s in patients with 6NP as this ha...
Source: Case Reports in Ophthalmology - February 7, 2022 Category: Opthalmology Source Type: research

Granular Cell Tumor in the Medial Rectus Muscle: A Case Report
An 80-year-old female complained of diplopia after undergoing cataract surgery. On the first examination, adduction and abduction were slightly restricted. Magnetic resonance imaging revealed a mass in the medial rectus muscle. The results of pathological examination of a specimen harvested from the mass corresponded to granular cell tumor. Although we could not completely excise the mass because of firm adhesion of the mass to the muscle, there was no recurrence without any suspicious metastatic lesion at 2.5 years of follow-up.Case Rep Ophthalmol 2022;13:33 –36 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 31, 2022 Category: Opthalmology Source Type: research

Branch Retinal Vein Occlusion after Messenger RNA-Based COVID-19 Vaccine
Two days after the second dose of the messenger RNA-based COVID-19 vaccine (BNT162b2), a healthy 38-year-old man developed branch retinal vein occlusion (BRVO) in his left eye (OS). His previous medical history was unremarkable and he was a nonsmoker. His blood pressure was 117/78 mm Hg. Blood examination did not suggest thrombophilia. His best-corrected visual acuity (BCVA) was 0.9 OS with myopic correction. A fundus examination showed a retinal hemorrhage and cotton wool spots in the superotemporal region of the posterior pole OS. Optical coherence tomography macular scans showed subfoveal fluid accumulation and retinal ...
Source: Case Reports in Ophthalmology - January 31, 2022 Category: Opthalmology Source Type: research

Cilioretinal Sparing Central Retinal Artery Occlusion from Giant Cell Arteritis
A 93-year-old woman presented with a 1-day history of sudden painless vision loss in her right eye with a background of new temporal headaches and jaw claudication. Dilated fundus examination of the right eye showed mild retinal whitening and edema throughout the right fundus with selective sparing in the distribution of the cilioretinal artery. A diagnosis of giant-cell arteritis (GCA) was made and confirmed with temporal artery biopsy. Oral prednisone was initiated and her vision improved to 20/200 in the right eye at 3-month follow-up. GCA-related cilioretinal artery sparing central retinal artery occlusion is rare and ...
Source: Case Reports in Ophthalmology - January 31, 2022 Category: Opthalmology Source Type: research

Corneal Graft Rejection after Descemet ’s Membrane Endothelial Keratoplasty with Peripheral Anterior Synechiae
Descemet ’s membrane endothelial keratoplasty (DMEK) for patients with corneal endothelial loss rarely results in graft rejection. Herein, we report a rare case of graft rejection following DMEK, in which peripheral anterior synechiae were observed postoperatively. A 66-year-old woman was referred to our h ospital after complaints of decreased visual acuity of her right eye after laser iridotomy for primary angle closure 3 years earlier. Her right cornea had bullous keratopathy with mild cataract, and her best-corrected visual acuity (BCVA) was 20/40. After cataract surgery, DMEK was successfully perf ormed, except for d...
Source: Case Reports in Ophthalmology - January 31, 2022 Category: Opthalmology Source Type: research

Deep Anterior Lamellar Keratoplasty and Peripheral Lamellar Keratoplasty for a Case of Severe Peripheral Ulcerative Keratitis
In conclusion, combined DALK and peripheral LK may be a surgical option for treating severe peripheral ulcerative keratitis.Case Rep Ophthalmol 2022;13:9 –16 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - January 18, 2022 Category: Opthalmology Source Type: research

A Case of Angioid Streaks in Congenital Dyserythropoietic Anaemia Type II
The authors describe a case report of retinal angioid streaks (AS) in a patient with congenital dyserythropoietic anaemia (CDA) type II and compare the retinal findings to those of an affected first-degree relative without ocular manifestations of the disease. A 52-year-old man with a confirmed diagnosis of CDA type II has been dependent on treatment with regular transfusions and chelating agents. He presents with bilateral retinal AS. The subject ’s brother, who also has CDA type II, underwent splenectomy in childhood, and has required no treatment since then. He has no ocular manifestations of the disease. To the autho...
Source: Case Reports in Ophthalmology - January 11, 2022 Category: Opthalmology Source Type: research

Decompensated Superior Oblique Palsy Secondary to Bilateral Nutritional Optic Neuropathy Following Bariatric Surgery
We present a unique case of a 39-year-old man, claiming to be generally healthy, who presented with intermittent vertical diplopia and bilateral decreased vision in each eye. Visual acuity was 6/18 in the right eye and 6/12 in the left eye. Ishihara testing was defective for both eyes. Automated visual fields showed a severe generalized reduction in sensitivity in both eyes. The patient had a left head tilt and a right intermittent hypertropia of 30 prism diopters in primary position. CT of the orbits revealed a right superior oblique of small caliber. On further questioning, the patient admitted to a history of bariatric ...
Source: Case Reports in Ophthalmology - December 30, 2021 Category: Opthalmology Source Type: research

Treatment of Bilateral Endogenous < b > < i > Aspergillus < /i > < /b > Endophthalmitis with Multiple Intravitreal Voriconazole Injections with Good Visual Outcome
Endogenous endophthalmitis caused byAspergillus species tends to be very aggressive, often leading to devastating visual outcomes. Historically, intravitreal amphotericin injections have played a central role in management, but with variable visual outcomes and a risk of toxicity. Limited reports suggest that use of intravitreal voriconazole is a safe and efficacious alternative, though these cases were treated with only few intravitreal injections. Here, we report a case of bilateral endogenousAspergillus endophthalmitis treated with 8 intravitreal voriconazole injections in the right eye and 11 in the left eye with good ...
Source: Case Reports in Ophthalmology - December 30, 2021 Category: Opthalmology Source Type: research

Acute Lymphoblastic Leukemia Relapse Limited to the Anterior Chamber of the Eye and Treated with Novel CAR T-Cell Therapy
Acute lymphoblastic leukemia (ALL) is a malignant neoplasm of the blood stem cells, characterized by increased formation of immature lymphocytes. Ocular manifestations may vary with ocular, adnexal, and orbital involvement. In this case report, we describe the first case of extramedullary relapse of ALL limited to the anterior chamber of the eye treated with the novel chimeric antigen receptor T (CAR T)-cell therapy and provide a literature review of cases of ALL relapse in the anterior chamber. A 21-year-old male with a history of B-cell ALL presented with a unilateral blurry vision in his left eye. Ocular examination rev...
Source: Case Reports in Ophthalmology - December 28, 2021 Category: Opthalmology Source Type: research