Presumed Melanoma of Unknown Primary Origin Metastatic to the Choroid Mimics Primary Uveal Melanoma
We describe the case of a 69-year-old woman who presented with a decline in vision in the left eye and was found to have a choroidal lesion with clinical and echographic features concerning for primary uveal melanoma. Systemic imaging identified numerous metastases to the liver, kidneys, paratracheal lymph nodes, lung, and brain. The hepatic lesion was biopsied, and genetic analysis identified a Val600Glu (c.1799T#x3e;A)BRAF mutation, consistent with a cutaneous primary malignancy, although no primary tumor was identified. This case highlights that metastasis to the choroid is a rare presentation of nonuveal melanoma that ...
Source: Case Reports in Ophthalmology - December 28, 2021 Category: Opthalmology Source Type: research
Subthreshold Laser Treatment for Serous Retinal Detachment Associated with Tilted Disc Syndrome
In conclusion, subthreshold laser photocoagulation is an effective treatment for SRD associated with TDS. Thus, the clinical indications of subthreshold laser photocoagulation may be extended to SRD in patients with TDS.Case Rep Ophthalmol 2021;12:978 –986 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - December 28, 2021 Category: Opthalmology Source Type: research
Acknowledgement to the Reviewers
Case Rep Ophthalmol 2021;12:975 –977 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - December 21, 2021 Category: Opthalmology Source Type: research
To Amputate or Not to Amputate: Management of Iatrogenic LASIK Flap Dehiscence and Epithelial Ingrowth with Overlying Pseudopterygium
A 73-year-old male with a history of myopic laser-assisted in situ keratomileusis (LASIK) 20 years earlier presented with a late LASIK flap dehiscence, epithelial ingrowth, conjunctivalization, and the development of a pseudopterygium in the right eye. The findings were consistent with surgical trauma, likely occurring after corneal epithelial debridement to improve visualization during pars plana vitrectomy for retinal detachment repair 3 months earlier. The patient underwent epithelial ingrowth debridement, LASIK flap reapproximation and suturing, and a conjunctival limbal autograft from the contralateral eye. The surger...
Source: Case Reports in Ophthalmology - December 20, 2021 Category: Opthalmology Source Type: research
Bilateral Diffuse Uveal Melanocytic Proliferation in a Woman with Metastatic Scalp Squamous Cell Carcinoma Treated with Cemiplimab
Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic intraocular syndrome that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. The IgG factor – cultured melanocyte elongation and proliferation – was found in the IgG fraction of the serum of BDUMP patients. It has been shown to be involved in melanocytic proliferation. In this case report, we describe the first case of BDUMP related to metastatic cutaneous squamous cell carcinoma (cSCC ) of the scalp. A 61-year-old woman complained of decreased vision in both of her eyes, while be...
Source: Case Reports in Ophthalmology - December 10, 2021 Category: Opthalmology Source Type: research
A Case of Vogt-Koyanagi-Harada Disease-Like Uveitis Induced by Nivolumab and Ipilimumab Combination Therapy
We report a case of VKH disease-like uveitis recurrence after resuming ICPIs. A 73-year-old man with advanced melanoma was referred to our clinic with visual loss 25 days after starting nivolumab/ipilimumab. His corrected visual acuity was 0.5 in the right eye and 0.02 in the left eye. Enhanced-depth imaging optical coherence tomography (EDI-OCT) showed marked choroid thickening. The patient was diagnosed with VKH disease-like uveitis due to IRAEs. Subtenon injection of triamcinolone acetonide was performed, and nivolumab/ipilimumab was suspended, but serous retinal detachment (SRD) markedly worsened and choroidal detachme...
Source: Case Reports in Ophthalmology - December 2, 2021 Category: Opthalmology Source Type: research
Ocular Surface Erosion after Suspected Exposure to Evaporated COVID-19 Vaccine
The purpose is to report ocular surface erosion of health personnel who were exposed to evaporated CoronaVac during a vaccination campaign. A campaign for CoronaVac vaccination was conducted in a closed space of 11.04 × 5.96 m, partially divided into 6 rooms with interconnected area among the rooms. A total of 20 health personnel worked in the vaccination rooms. On the third day of campaign, a vial, containing a single dose of 0.5 mL, of the vaccine was dropped accidentally onto the floor and broken by an admini stering nurse. A total of 15 personnel had symptoms and signs of ocular surface erosion at the average time fro...
Source: Case Reports in Ophthalmology - December 2, 2021 Category: Opthalmology Source Type: research
Pre-Descemetic Placement of Intracorneal Ring Segments for Keratoconus after Mechanical Implantation
We report the case of a 23-year-old male who was referred to our clinic for a routine follow-up examination. The patient was treated for keratoconus 3 years ago in Colombia, where intracorneal ring segments were implanted mechanically in both eyes to improve his visual acuity. Surprisingly, we discovered a pre-descemetic placement of intracorneal ring segments, which could lead to potential complications, under circumstances. We illustrate this impressive finding with slit-lamp photography and high-resolution anterior segment OCT and advocate for the use of femtosecond laser as the method of choice for intracorneal ring se...
Source: Case Reports in Ophthalmology - December 2, 2021 Category: Opthalmology Source Type: research
Ocular TASER Probe Injury Managed with Primary Evisceration: Case Report
A 34-year-old male presented to the emergency department with a penetrating injury of the left globe and orbit from a Thomas A Swift ’s Electric Rifle (TASER®) probe. The severity of the globe injury precluded primary closure of the globe; a primary evisceration was performed. In this article, we discuss not only the case in detail but also the TASER® rifle and the literature to support our decision in performing an evisceration rather than an enucleation, which historically has been taught to decrease the risk of sympathetic ophthalmia (SO) in the fellow eye. We are of the opinion, after reviewing the literature, that...
Source: Case Reports in Ophthalmology - November 30, 2021 Category: Opthalmology Source Type: research
Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
A 19-year-old Caucasian woman was referred to the emergency room and thereafter to the department of ophthalmology complaining for bilateral decrease of visual acuity and severe pain. A complete ophthalmological evaluation was performed. Best-corrected visual acuity (BCVA) was LogMAR 0.3 in the right eye (RE) and LogMAR 0.5 in the left eye (LE). Intraocular pressure (IOP) was 28 and 38 mm Hg in the RE and LE, respectively. The patient showed a shallow anterior chamber and spherical equivalent refractive error −29.0 diopters (D) in the RE and −30.0 D in the LE. The diagnosis of bilateral angle closure glaucoma, secondar...
Source: Case Reports in Ophthalmology - November 25, 2021 Category: Opthalmology Source Type: research
< b > < i > Agrobacterium radiobacter < /i > < /b > Endophthalmitis Associated with Baerveldt Tube Exposure
This report illustrates the resistant nature of this organism in addition to the efficacy of silicone oil administration and intraocular prosthesis explantation.Case Rep Ophthalmol 2021;12:921 –926 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - November 25, 2021 Category: Opthalmology Source Type: research
Vitreous and Optic Nerve Infiltration of an Adrenal B Lymphoma
This study aimed to report a case of vitreous and optic nerve infiltration of a primary adrenal B lymphoma.Case Report: An 81-year-old patient consulted for decrease in vision in the left eye and pain with ocular movements during the last week. The patient was being treated with chemotherapy for an adrenal gland diffuse large B-cell lymphoma. On examination, vitritis was seen in both eyes and optic disc edema in his left eye. After an extensive study based on orbital and brain magnetic resonance imaging and vitreous cytology, an ocular infiltration by systemic B lymphoma was confirmed. A treatment based on intravitreal met...
Source: Case Reports in Ophthalmology - November 16, 2021 Category: Opthalmology Source Type: research
Bilateral Adie ’s Pupil following Laser Treatment of the Ischemic Peripheral Retina for Uveitis: A Case Report
We describe a patient who experienced varying severities of Adie’s pupil after separate laser treatments of the ischemic peripheral retina for uveitis. Fluorescein angiography revealed peripheral retinal nonperfusion in the bilateral eyes of a 37 -year-old Japanese female who had been suffering from posterior uveitis. To avoid proliferative changes, 360° laser photocoagulation of the retinal nonperfusion region located in the far periphery was first delivered to the left eye over 2 sessions. Soon after treatment, the patient complained of a cute photophobia and blurred vision in the treated eye. Ocular examination revea...
Source: Case Reports in Ophthalmology - November 11, 2021 Category: Opthalmology Source Type: research
Optic Nerve Head Microcirculation in Eyes with Vogt-Koyanagi-Harada Disease Accompanied by Anterior Ischemic Optic Neuropathy
Anterior ischemic optic neuropathy (AION) is infrequently complicated with Vogt-Koyanagi-Harada (VKH) disease. We quantitatively examined sequential changes in the morphology and circulation hemodynamics, using a C-scan of optical coherence tomography (OCT) and laser speckle flowgraphy (LSFG) in a patient with VKH disease accompanied by AION. A 65-year-old female complained of blurred vision in both of her eyes. The patient presented with optic disc swelling and remarkable choroidal thickening detected by OCT bilaterally. The diagnosis of VKH disease was established based on the presence of pleocytosis detected in the cere...
Source: Case Reports in Ophthalmology - November 8, 2021 Category: Opthalmology Source Type: research
Suprachoroidal Gas: A Rare Complication of Intravitreal Injection of Perfluoropropane
This report also serves as a review of the current state of knowledge in the area of suprachoroidal gas as a complication of pneumatic retinopexy and sutureless vitrectomy.Case Rep Ophthalmol 2021;12:894 –898 (Source: Case Reports in Ophthalmology)
Source: Case Reports in Ophthalmology - November 8, 2021 Category: Opthalmology Source Type: research
