Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

Associations between Different Antivirals and Hospital acquired Acute Kidney Injury in Adults with Herpes Zoster
CONCLUSIONS: Among antiviral therapies for herpes zoster, we found different risks of hospital acquired AKI among the patients receiving different antivirals, in particular, those administered intravenously. Among intravenous antivirals, acyclovir was associated with highest risk of hospital acquired AKI, followed by penciclovir/ganciclovir and foscarnet. Confirmation studies with large samples from other populations are warranted.PMID:38527975 | DOI:10.2215/CJN.0000000000000452 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - March 26, 2024 Category: Urology & Nephrology Authors: Ruqi Xu Qi Gao Yuping Zhang Yuxin Lin Yanqin Li Licong Su Shiyu Zhou Yue Cao Peiyan Gao Pingping Li Fan Luo Ruixuan Chen Xiaodong Zhang Sheng Nie Xin Xu CRDS study Investigators Source Type: research

The combination of oral valacyclovir with topical clobetasol therapy was the most effective in reducing the time to heal from herpes labialis
J Evid Based Dent Pract. 2024 Mar;24(1):101962. doi: 10.1016/j.jebdp.2023.101962. Epub 2023 Dec 21.ABSTRACTARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Koe KH, Veettil SK, Maharajan MK, Syeed MS, Nair AB, Gopinath D. comparative efficacy of antiviral agents for prevention and management of herpes labialis: A systematic review and network meta-analysis. J Evid Based Dent Pract. 2023 Mar; 23(1):101778. doi: 10.1016/j.jebdp.2022.101778. Epub 2022 Sep 14. PMID: 36914303.SOURCE OF FUNDING: None.TYPE OF STUDY/DESIGN: Systematic review with meta-analysis.PMID:38448120 | DOI:10.1016/j.jebdp.2023.101962 (Source: Herpes)
Source: Herpes - March 6, 2024 Category: Infectious Diseases Authors: Sung-Kiang Chuang Jie Han Timothy Sng Source Type: research

Vasculitis-like herpes zoster in the course of treatment with tofacitinib in ulcerative colitis: An assessment of local viral distribution by RNA in situ hybridization
J Dermatol. 2024 Feb 27. doi: 10.1111/1346-8138.17169. Online ahead of print.ABSTRACTA 67-year-old man had taken the janus kinase (JAK) inhibitor, tofacitinib, for ulcerative colitis. He was referred to our department for a refractory ulcer on his lower leg. We suspected vasculitis and performed skin biopsy. Histopathological examination showed multinucleated giant cells in the epidermis and fibrinoid degeneration of small vessels in the upper dermis. Varicella zoster virus (VZV) DNA was detected by polymerase chain reaction and we diagnosed the patient with atypical vasculitis-like herpes zoster. The patient was treated w...
Source: Herpes - February 28, 2024 Category: Infectious Diseases Authors: Eri Uchiyama Reimon Yamaguchi Kazushi Anzawa Toshiki Fujii Daisuke Watanabe Akira Shimizu Source Type: research

Vasculitis-like herpes zoster in the course of treatment with tofacitinib in ulcerative colitis: An assessment of local viral distribution by RNA in situ hybridization
J Dermatol. 2024 Feb 27. doi: 10.1111/1346-8138.17169. Online ahead of print.ABSTRACTA 67-year-old man had taken the janus kinase (JAK) inhibitor, tofacitinib, for ulcerative colitis. He was referred to our department for a refractory ulcer on his lower leg. We suspected vasculitis and performed skin biopsy. Histopathological examination showed multinucleated giant cells in the epidermis and fibrinoid degeneration of small vessels in the upper dermis. Varicella zoster virus (VZV) DNA was detected by polymerase chain reaction and we diagnosed the patient with atypical vasculitis-like herpes zoster. The patient was treated w...
Source: Herpes - February 28, 2024 Category: Infectious Diseases Authors: Eri Uchiyama Reimon Yamaguchi Kazushi Anzawa Toshiki Fujii Daisuke Watanabe Akira Shimizu Source Type: research

Baseline Participant Characteristics at Enrollment in the Zoster Eye Disease Study
CONCLUSIONS: The broad ZEDS study population enhances the likelihood that ZEDS will provide generalizable high-quality evidence regarding the efficacy and safety of suppressive valacyclovir for HZO immunocompetent adults and whether it should become standard of care.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03134196.PMID:38411973 | DOI:10.1097/ICO.0000000000003497 (Source: Herpes)
Source: Herpes - February 27, 2024 Category: Infectious Diseases Authors: Christina R Prescott Elisabeth J Cohen Judith S Hochman Andrea B Troxel Ying Lu Alberta Twi-Yeboah Carlos Lopez Jimenez Shahzad I Mian Choulakian Y Mazen David B Warner Keith H Baratz Bennie H Jeng ZEDS Trial Research Group Source Type: research

Pharmacologic interventions for the treatment of equine herpesvirus-1 in domesticated horses: A systematic review
CONCLUSIONS AND CLINICAL IMPORTANCE: Our review indicates minimal or limited benefit either as a prophylactic or post-exposure treatment for any of the studied interventions in the mitigation of EHV-1-associated disease outcome.PMID:38380685 | DOI:10.1111/jvim.17016 (Source: Herpes)
Source: Herpes - February 21, 2024 Category: Infectious Diseases Authors: Lutz Goehring David C Dorman Klaus Osterrieder Brandy A Burgess Kelsie Dougherty Peggy Gross Claire Neinast Nicola Pusterla Gisela Soboll-Hussey David P Lunn Source Type: research