Acute-Onset Postoperative Herpetic Endophthalmitis: A Case Report
We report a rare case of acute-onset herpetic endophthalmitis presenting within 72 hours following cataract surgery for a complicated cataract in a patient with a history of pre-existing healed viral keratitis. Our case highlights that a suspicion of viral endophthalmitis should be kept in mind as a cause of acute-onset post-cataract surgery endophthalmitis, especially in cases of surgery that fail to yield a positive result on Gram's stain, culture or PCR for bacteria and fungi.PMID:37492828 | PMC:PMC10363650 | DOI:10.7759/cureus.40875 (Source: Herpes)
Source: Herpes - July 26, 2023 Category: Infectious Diseases Authors: Vinita Gupta Umesh Yadav Saurabh Luthra Anurag Singla Source Type: research
Acute-Onset Postoperative Herpetic Endophthalmitis: A Case Report
We report a rare case of acute-onset herpetic endophthalmitis presenting within 72 hours following cataract surgery for a complicated cataract in a patient with a history of pre-existing healed viral keratitis. Our case highlights that a suspicion of viral endophthalmitis should be kept in mind as a cause of acute-onset post-cataract surgery endophthalmitis, especially in cases of surgery that fail to yield a positive result on Gram's stain, culture or PCR for bacteria and fungi.PMID:37492828 | PMC:PMC10363650 | DOI:10.7759/cureus.40875 (Source: Herpes)
Source: Herpes - July 26, 2023 Category: Infectious Diseases Authors: Vinita Gupta Umesh Yadav Saurabh Luthra Anurag Singla Source Type: research
Case Report of Herpes Zoster Ophthalmicus with Concurrent Parotitis
J Educ Teach Emerg Med. 2023 Apr 30;8(2):V6-V10. doi: 10.21980/J8R93N. eCollection 2023 Apr.ABSTRACTA 36-year-old immunocompetent female presented to the emergency department (ED) with five days of headache and left-sided facial pain. Physical exam showed conjunctival injection of the left eye with multiple vesicular lesions distributed along the V1 dermatome. Labs were remarkable for mild elevation in erythrocyte sedimentation rate (ESR) and c-reactive protein (CRP) with no elevation in white blood cell (WBC) count. Computed tomography (CT) with contrast of the neck revealed soft tissue stranding around the parotid gland....
Source: Herpes - July 19, 2023 Category: Infectious Diseases Authors: Serena Tally Michelle Brown Edmund Hsu Source Type: research
Case Report of Herpes Zoster Ophthalmicus with Concurrent Parotitis
J Educ Teach Emerg Med. 2023 Apr 30;8(2):V6-V10. doi: 10.21980/J8R93N. eCollection 2023 Apr.ABSTRACTA 36-year-old immunocompetent female presented to the emergency department (ED) with five days of headache and left-sided facial pain. Physical exam showed conjunctival injection of the left eye with multiple vesicular lesions distributed along the V1 dermatome. Labs were remarkable for mild elevation in erythrocyte sedimentation rate (ESR) and c-reactive protein (CRP) with no elevation in white blood cell (WBC) count. Computed tomography (CT) with contrast of the neck revealed soft tissue stranding around the parotid gland....
Source: Herpes - July 19, 2023 Category: Infectious Diseases Authors: Serena Tally Michelle Brown Edmund Hsu Source Type: research
Universal screening programme for cytomegalovirus infection in the first trimester of pregnancy: study protocol for an observational multicentre study in the area of Barcelona (CITEMB study)
Introduction
Congenital cytomegalovirus (cCMV) is the leading cause of non-genetic sensorineural hearing loss and one of the main causes of neurological disability. Despite this, no universal screening programme for cCMV has been implemented in Spain. A recent study has shown that early treatment with valaciclovir, initiated in the first trimester and before the onset of signs in the fetus, reduces the risk of fetal infection. This finding favours the implementation of a universal screening programme for cCMV.
The aim of this study is to evaluate the performance of a universal screening programme for cCMV during the first ...
Source: BMJ Open - July 19, 2023 Category: General Medicine Authors: Sanchez-Duran, M. A., Maiz, N., Liutsko, L., Bielsa-Pascual, J., Garcia-Sierra, R., Zientalska, A. M., Velasco, I., Vazquez, E., Gracia, O., Ribas, A., Sitja, N., Nadales, M., Martinez, C., Gonce, A., Frick, M. A., Guerrero-Martinez, M., Violan, C., Toran Tags: Open access, Infectious diseases Source Type: research
The effect of valacyclovir on secondary prevention of congenital cytomegalovirus infection, following primary maternal infection acquired periconceptionally or in the first trimester of pregnancy. An individual patient data meta-analysis
Recent studies have showed that oral valacyclovir 8g/day reduces significantly the vertical CMV transmission rate in women with primary CMV infection acquired periconceptionally or during the first trimester. The present individual patient data meta-analysis aims to assess the effectiveness and safety of valacyclovir treatment in the secondary prevention of congenital CMV infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 18, 2023 Category: OBGYN Authors: Christos Chatzakis, Karen Shahar-nissan, Valentine Faure-bardon, Olivier Picone, Eran Hadar, Jacob Amir, Charles Egloff, Alexandre Vivanti, Alexandros Sotiriadis, Marianne Leruez-ville, Yves Ville Tags: Systematic Review Source Type: research
The effect of valacyclovir on secondary prevention of congenital cytomegalovirus infection, following primary maternal infection acquired periconceptionally or in the first trimester of pregnancy. An individual patient data meta-analysis
Recent studies have shown that a dosage of 8 g/d of oral valacyclovir reduces substantially the vertical transmission rate of cytomegalovirus in women with primary cytomegalovirus infection acquired periconceptionally or during the first trimester of pregnancy. This individual patient data meta-analysis aimed to assess the effectiveness and safety of valacyclovir treatment in the secondary prevention of congenital cytomegalovirus infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 18, 2023 Category: OBGYN Authors: Christos Chatzakis, Karen Shahar-Nissan, Valentine Faure-Bardon, Olivier Picone, Eran Hadar, Jacob Amir, Charles Egloff, Alexandre Vivanti, Alexandros Sotiriadis, Marianne Leruez-Ville, Yves Ville Tags: Systematic Review Source Type: research
Focal Posterior Herpetic Retinitis
Ocul Immunol Inflamm. 2023 Jul 11:1-4. doi: 10.1080/09273948.2023.2230261. Online ahead of print.ABSTRACTDespite having 20/20 vision, a 17-year-old Emirati female presented with central visual changes in her left eye. These changes were attributed to a dull foveal reflex with pigmentary alterations. Retinal pigment epithelium (RPE) mottling at the macula level, attenuating the ellipsoid zone, and a hyper-reflective line connecting the RPE to the outer nuclear layer was observed through spectral domain optical coherence tomography (SD-OCT) of the left eye. In the presence of negative results from laboratory evaluations, the...
Source: Herpes - July 11, 2023 Category: Infectious Diseases Authors: Sahar H AlAli Piergiorgio Neri Francesco Pichi Source Type: research
Focal Posterior Herpetic Retinitis
Ocul Immunol Inflamm. 2023 Jul 11:1-4. doi: 10.1080/09273948.2023.2230261. Online ahead of print.ABSTRACTDespite having 20/20 vision, a 17-year-old Emirati female presented with central visual changes in her left eye. These changes were attributed to a dull foveal reflex with pigmentary alterations. Retinal pigment epithelium (RPE) mottling at the macula level, attenuating the ellipsoid zone, and a hyper-reflective line connecting the RPE to the outer nuclear layer was observed through spectral domain optical coherence tomography (SD-OCT) of the left eye. In the presence of negative results from laboratory evaluations, the...
Source: Ocular Immunology and Inflammation - July 11, 2023 Category: Allergy & Immunology Authors: Sahar H AlAli Piergiorgio Neri Francesco Pichi Source Type: research
Acyclovir-Resistant Anogenital Herpes Simplex Virus in an HIV Patient With Pseudoepitheliomatous Hyperplasia Resembling Squamous Cell Carcinoma
CONCLUSION: Atypical, chronic presentations of HSV are common in immunocompromised patients. Hypertrophic HSV is the least common clinical presentation and can be mistaken for squamous cell carcinoma, creating difficulty in diagnosis. Due to concerns for malignancy, our patient's lesions were biopsied, which revealed prominent PEH. While PEH is benign, it can be misdiagnosed as squamous cell carcinoma on histopathology, particularly when there is clinical suspicion for malignancy. In these cases, the clinician needs to alert the pathologist to the immunosuppressed status of the patient. Detailed evaluation for infectious c...
Source: Herpes - July 10, 2023 Category: Infectious Diseases Authors: Jean Elizze M Charles Stephen E Weis Gregory A Hosler Source Type: research
Acyclovir-Resistant Anogenital Herpes Simplex Virus in an HIV Patient With Pseudoepitheliomatous Hyperplasia Resembling Squamous Cell Carcinoma
CONCLUSION: Atypical, chronic presentations of HSV are common in immunocompromised patients. Hypertrophic HSV is the least common clinical presentation and can be mistaken for squamous cell carcinoma, creating difficulty in diagnosis. Due to concerns for malignancy, our patient's lesions were biopsied, which revealed prominent PEH. While PEH is benign, it can be misdiagnosed as squamous cell carcinoma on histopathology, particularly when there is clinical suspicion for malignancy. In these cases, the clinician needs to alert the pathologist to the immunosuppressed status of the patient. Detailed evaluation for infectious c...
Source: Herpes - July 10, 2023 Category: Infectious Diseases Authors: Jean Elizze M Charles Stephen E Weis Gregory A Hosler Source Type: research
Varicella Zoster Meningitis in a Young, Immunocompetent Patient Despite Initiation of Antiviral Therapy
Cureus. 2023 Jun 5;15(6):e39980. doi: 10.7759/cureus.39980. eCollection 2023 Jun.ABSTRACTVaricella zoster virus (VZV) reactivation, also known as herpes zoster is common in older adults and immunocompromised individuals and often causes a painful, vesicular rash limited to a dermatomal distribution. On occasion, it can lead to various neurological complications as well. Here we present the case of a young, immunocompetent male in his 20's with a history of primary varicella infection who presented with complaints of a painful rash in the S3-S4 dermatomal distribution. Despite being initiated on the standard oral antiviral ...
Source: Herpes - July 7, 2023 Category: Infectious Diseases Authors: Yashitha Chirumamilla Sania Ajmal Bhawuk Subedi Ghassan Bachuwa Basim Towfiq Source Type: research
The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 1-global current practice patterns for the management of Herpes Simplex Virus and Varicella Zoster Virus anterior uveitis
CONCLUSIONS: Consensus was reached on several aspects of diagnosis, choice of initial treatment, and treatment endpoints for HSV and VZV AU. Treatment duration and management of recurrences varied between experts.PMID:37419957 | DOI:10.1038/s41433-023-02630-9 (Source: Herpes)
Source: Herpes - July 7, 2023 Category: Infectious Diseases Authors: Zheng Xian Thng Ikhwanuliman Putera Ilaria Testi Kevin Chan Mark Westcott Soon-Phaik Chee Andrew D Dick John H Kempen Bahram Bodaghi Jennifer E Thorne Talin Barisani-Asenbauer Marc D de Smet Justine R Smith Peter McCluskey Rina La Distia Nora Douglas A Ja Source Type: research
Varicella Zoster Meningitis in a Young, Immunocompetent Patient Despite Initiation of Antiviral Therapy
Cureus. 2023 Jun 5;15(6):e39980. doi: 10.7759/cureus.39980. eCollection 2023 Jun.ABSTRACTVaricella zoster virus (VZV) reactivation, also known as herpes zoster is common in older adults and immunocompromised individuals and often causes a painful, vesicular rash limited to a dermatomal distribution. On occasion, it can lead to various neurological complications as well. Here we present the case of a young, immunocompetent male in his 20's with a history of primary varicella infection who presented with complaints of a painful rash in the S3-S4 dermatomal distribution. Despite being initiated on the standard oral antiviral ...
Source: Herpes - July 7, 2023 Category: Infectious Diseases Authors: Yashitha Chirumamilla Sania Ajmal Bhawuk Subedi Ghassan Bachuwa Basim Towfiq Source Type: research
Treatment outcomes of PCR-positive acute retinal necrosis
ConclusionsOur review found increased incidence of CMV-positive ARN. Patients with zone 1 disease had worse initial visual acuity. Moreover, patients had more favorable outcomes with V2T and V9B compared to V1T. CMV-positive patients clinically worsened after intravitreal steroid injections, further underscoring the value of a PCR diagnosis to tailor the patients ’ treatment plan accordingly. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - June 27, 2023 Category: General Medicine Source Type: research
