High-dose valacyclovir to prevent congenital cytomegalovirus transmission in pregnancy: is it possible to reduce major side effects?
Ultrasound Obstet Gynecol. 2023 Apr;61(4):539-540. doi: 10.1002/uog.26193.NO ABSTRACTPMID:37011081 | DOI:10.1002/uog.26193 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - April 3, 2023 Category: Radiology Authors: M De Santis T G Vitelli R Santangelo A Lanzone S Tartaglia Source Type: research
Bell Palsy: Facts and Current Research Perspectives
CNS Neurol Disord Drug Targets. 2023 Mar 21. doi: 10.2174/1871527322666230321120618. Online ahead of print.ABSTRACTBell palsy is a non-progressive neurological condition characterized by the acute onset of ipsilateral seventh cranial nerve paralysis. People who suffer from this type of facial paralysis develop a droop on one side of their face, or sometimes both. This condition is distinguished by a sudden onset of facial paralysis accompanied by clinical features such as mild fever, postauricular pain, dysgeusia, hyperacusis, facial changes, and drooling or dry eyes. Epidemiological evidence suggests that 15 to 23 people ...
Source: CNS and Neurological Disorders Drug Targets - March 24, 2023 Category: Drugs & Pharmacology Authors: Jayaraman Rajangam Arun Prasath Lakshmanan K Umamaheswara Rao D Jayashree Rajan Radhakrishnan B Roshitha Palanisamy Sivanandy M Jyothi Sravani K Hanna Pravalika Source Type: research
Bell Palsy: Facts and Current Research Perspectives
CNS Neurol Disord Drug Targets. 2023 Mar 21. doi: 10.2174/1871527322666230321120618. Online ahead of print.ABSTRACTBell palsy is a non-progressive neurological condition characterized by the acute onset of ipsilateral seventh cranial nerve paralysis. People who suffer from this type of facial paralysis develop a droop on one side of their face, or sometimes both. This condition is distinguished by a sudden onset of facial paralysis accompanied by clinical features such as mild fever, postauricular pain, dysgeusia, hyperacusis, facial changes, and drooling or dry eyes. Epidemiological evidence suggests that 15 to 23 people ...
Source: CNS and Neurological Disorders Drug Targets - March 24, 2023 Category: Drugs & Pharmacology Authors: Jayaraman Rajangam Arun Prasath Lakshmanan K Umamaheswara Rao D Jayashree Rajan Radhakrishnan B Roshitha Palanisamy Sivanandy M Jyothi Sravani K Hanna Pravalika Source Type: research
Bell Palsy: Facts and Current Research Perspectives
CNS Neurol Disord Drug Targets. 2023 Mar 21. doi: 10.2174/1871527322666230321120618. Online ahead of print.ABSTRACTBell palsy is a non-progressive neurological condition characterized by the acute onset of ipsilateral seventh cranial nerve paralysis. People who suffer from this type of facial paralysis develop a droop on one side of their face, or sometimes both. This condition is distinguished by a sudden onset of facial paralysis accompanied by clinical features such as mild fever, postauricular pain, dysgeusia, hyperacusis, facial changes, and drooling or dry eyes. Epidemiological evidence suggests that 15 to 23 people ...
Source: CNS and Neurological Disorders Drug Targets - March 24, 2023 Category: Drugs & Pharmacology Authors: Jayaraman Rajangam Arun Prasath Lakshmanan K Umamaheswara Rao D Jayashree Rajan Radhakrishnan B Roshitha Palanisamy Sivanandy M Jyothi Sravani K Hanna Pravalika Source Type: research
Bell Palsy: Facts and Current Research Perspectives
CNS Neurol Disord Drug Targets. 2023 Mar 21. doi: 10.2174/1871527322666230321120618. Online ahead of print.ABSTRACTBell palsy is a non-progressive neurological condition characterized by the acute onset of ipsilateral seventh cranial nerve paralysis. People who suffer from this type of facial paralysis develop a droop on one side of their face, or sometimes both. This condition is distinguished by a sudden onset of facial paralysis accompanied by clinical features such as mild fever, postauricular pain, dysgeusia, hyperacusis, facial changes, and drooling or dry eyes. Epidemiological evidence suggests that 15 to 23 people ...
Source: CNS and Neurological Disorders Drug Targets - March 24, 2023 Category: Drugs & Pharmacology Authors: Jayaraman Rajangam Arun Prasath Lakshmanan K Umamaheswara Rao D Jayashree Rajan Radhakrishnan B Roshitha Palanisamy Sivanandy M Jyothi Sravani K Hanna Pravalika Source Type: research
Genital Herpes Simplex Virus Type 2 Suppression With Valacyclovir Is Not Associated With Changes in Nugent Score or Absolute Abundance of Key Vaginal Bacteria
CONCLUSIONS: Short-term HSV-2 suppression with valacyclovir did not significantly affect the Nugent score or the vaginal microbiome despite potent suppression of HSV-2 shedding.PMID:36949872 | PMC:PMC10026542 | DOI:10.1093/ofid/ofad099 (Source: Herpes)
Source: Herpes - March 23, 2023 Category: Infectious Diseases Authors: Tara M Babu Sujatha Srinivasan Amalia Magaret Sean Proll Helen Stankiewicz Karita Jacqueline M Wallis Stacy Selke Dana Varon Thepthara Pholsena David Fredricks Jeanne Marrazzo Anna Wald Christine Johnston Source Type: research
Genital Herpes Simplex Virus Type 2 Suppression With Valacyclovir Is Not Associated With Changes in Nugent Score or Absolute Abundance of Key Vaginal Bacteria
CONCLUSIONS: Short-term HSV-2 suppression with valacyclovir did not significantly affect the Nugent score or the vaginal microbiome despite potent suppression of HSV-2 shedding.PMID:36949872 | PMC:PMC10026542 | DOI:10.1093/ofid/ofad099 (Source: Herpes)
Source: Herpes - March 23, 2023 Category: Infectious Diseases Authors: Tara M Babu Sujatha Srinivasan Amalia Magaret Sean Proll Helen Stankiewicz Karita Jacqueline M Wallis Stacy Selke Dana Varon Thepthara Pholsena David Fredricks Jeanne Marrazzo Anna Wald Christine Johnston Source Type: research
Clinical features and prognostic factors in adults with viral meningitis
Brain. 2023 Mar 16:awad089. doi: 10.1093/brain/awad089. Online ahead of print.ABSTRACTClinical features applicable to the entire spectrum of viral meningitis are limited, and prognostic factors for adverse outcomes are undetermined. This nationwide population-based prospective cohort study included all adults with presumed and microbiologically confirmed viral meningitis in Denmark from 2015 until 2020. Prognostic factors for an unfavourable outcome (Glasgow Outcome Scale score of 1-4) 30 days after discharge were examined by modified Poisson regression. In total, 1066 episodes of viral meningitis were included, yielding a...
Source: Herpes - March 17, 2023 Category: Infectious Diseases Authors: Pelle Trier Petersen Jacob Bodilsen Micha Phill Gr ønholm Jepsen Lykke Larsen Merete Storgaard Birgitte R ønde Hansen Jannik Helweg-Larsen Lothar Wiese Hans Rudolf L üttichau Christian Østergaard Andersen Henrik Nielsen Christian Thomas Brandt Danish Source Type: research
Clinical features and prognostic factors in adults with viral meningitis
Brain. 2023 Mar 16:awad089. doi: 10.1093/brain/awad089. Online ahead of print.ABSTRACTClinical features applicable to the entire spectrum of viral meningitis are limited, and prognostic factors for adverse outcomes are undetermined. This nationwide population-based prospective cohort study included all adults with presumed and microbiologically confirmed viral meningitis in Denmark from 2015 until 2020. Prognostic factors for an unfavourable outcome (Glasgow Outcome Scale score of 1-4) 30 days after discharge were examined by modified Poisson regression. In total, 1066 episodes of viral meningitis were included, yielding a...
Source: Herpes - March 17, 2023 Category: Infectious Diseases Authors: Pelle Trier Petersen Jacob Bodilsen Micha Phill Gr ønholm Jepsen Lykke Larsen Merete Storgaard Birgitte R ønde Hansen Jannik Helweg-Larsen Lothar Wiese Hans Rudolf L üttichau Christian Østergaard Andersen Henrik Nielsen Christian Thomas Brandt Danish Source Type: research
Clinical features and prognostic factors in adults with viral meningitis
AbstractClinical features applicable to the entire spectrum of viral meningitis are limited, and prognostic factors for adverse outcomes are undetermined.This nationwide population-based prospective cohort study included all adults with presumed and microbiologically confirmed viral meningitis in Denmark from 2015 until 2020. Prognostic factors for an unfavourable outcome (Glasgow Outcome Scale score of 1 –4) 30 days after discharge were examined by modified Poisson regression.In total, 1066 episodes of viral meningitis were included, yielding a mean annual incidence of 4.7 episodes per 100 000 persons. Pathogens were en...
Source: Brain - March 16, 2023 Category: Neurology Source Type: research
Comparative efficacy of antiviral agents for prevention and management of herpes labialis: a systematic review and network meta-analysis
CONCLUSION: NMA highlighted that several agents were effective in the management of herpes labialis among which the combination of oral valacyclovir with topical clobetasol therapy was the most effective in reducing the time to heal. However, further studies are required to determine which intervention is the most effective in preventing the recurrence of herpes labialis.PMID:36914303 | DOI:10.1016/j.jebdp.2022.101778 (Source: Herpes)
Source: Herpes - March 13, 2023 Category: Infectious Diseases Authors: Kim Hoe Koe Sajesh K Veettil Mari Kannan Maharajan M Sakil Syeed Athira Balakrishnan Nair Divya Gopinath Source Type: research
Refractory < em > Candida dubliniensis < /em > Retinitis in an Immunocompetent Patient
CONCLUSION: Candida dubliniensisendophthalmitis can affect immunocompetent individuals and require a prolonged treatment course.PMID:36867499 | DOI:10.1080/09273948.2023.2185264 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 3, 2023 Category: Allergy & Immunology Authors: Fahmeeda Murtaza Austin Pereira H Nida Sen Henry E Wiley Panos G Christakis Source Type: research
Refractory < em > Candida dubliniensis < /em > Retinitis in an Immunocompetent Patient
CONCLUSION: Candida dubliniensis endophthalmitis can affect immunocompetent individuals and require a prolonged treatment course.PMID:36867499 | DOI:10.1080/09273948.2023.2185264 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 3, 2023 Category: Allergy & Immunology Authors: Fahmeeda Murtaza Austin Pereira H Nida Sen Henry E Wiley Panos G Christakis Source Type: research
