Treatment outcomes of PCR-positive acute retinal necrosis
CONCLUSIONS: Our review found increased incidence of CMV-positive ARN. Patients with zone 1 disease had worse initial visual acuity. Moreover, patients had more favorable outcomes with V2T and V9B compared to V1T. CMV-positive patients clinically worsened after intravitreal steroid injections, further underscoring the value of a PCR diagnosis to tailor the patients' treatment plan accordingly.PMID:37365446 | DOI:10.1007/s11845-023-03426-2 (Source: Herpes)
Source: Herpes - June 26, 2023 Category: Infectious Diseases Authors: Ahmad M Sidiqi Mahadev Bhalla Haaris M Khan Forson Chan Christopher Lowe Eduardo V Navajas Source Type: research
Inhibition of < em > BPHL < /em > inhibits proliferation in lung carcinoma cell lines
CONCLUSIONS: In this study, the data indicate that BPHL potentially promotes proliferation, inhibits apoptosis, and increases colony formation and metastasis in lung cancer. Overall, our study suggests that BPHL may be a gene that promotes tumor growth in lung cancer.PMID:37323178 | PMC:PMC10261862 | DOI:10.21037/tlcr-23-225 (Source: Cell Research)
Source: Cell Research - June 16, 2023 Category: Cytology Authors: Pengfei Ren Jianxue Zhai Xuelian Wang Yucheng Yin Zuju Lin Kaican Cai Haofei Wang Source Type: research
Long-term follow-up of acute retinal necrosis with retinal detachment secondary to herpes simplex virus type 2 with a successful visual outcome
BMJ Case Rep. 2023 Apr 26;16(4):e252913. doi: 10.1136/bcr-2022-252913.ABSTRACTA man in his early 20s presented with acute loss of vision in his only eye, the left eye (OS), and was on oral steroids. He had lost vision in his right eye during his childhood and the cause was unknown. There was no history of trauma. Best-corrected visual acuity (BCVA) in OS was 20/100 and in the right eye was hand movements. OS showed non-granulomatous keratic precipitates on the cornea, anterior chamber flare 1+ and cell 1+, early cataract, vitreous haze and cells 2+ with nasal retinal detachment and superior full thickness retinitis. He und...
Source: Herpes - May 15, 2023 Category: Infectious Diseases Authors: Srinivasan Sanjay Shama Sharief Aishwarya Joshi Naresh Kumar Yadav Source Type: research
Epstein-Barr Virus Keratouveitis-Induced Malignant Glaucoma After Penetrating Keratoplasty: A Case Report and Literature Review
CONCLUSIONS: EBV endotheliitis and anterior uveitis can induce malignant glaucoma following PK. A high index of suspicion is required when a patient has a history of unexplained multiple graft rejections.PMID:37155286 | DOI:10.1080/09273948.2023.2208659 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 8, 2023 Category: Allergy & Immunology Authors: Varintorn Chuckpaiwong Prae Phimpho Kaevalin Lekhanont Puttiya Kaewkorn Passara Jongkhajornpong Source Type: research
Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles: comprehensive spectroscopic study
The direct binding of antiviral agents; Daclatasvir and valacyclovir and green synthesized nanoparticles to salmon sperm DNA have been assessed in a comparative study. The nanoparticles were synthesized by the... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - April 19, 2023 Category: Chemistry Authors: Ahmed Faried Abdel Hakiem, Ahmed Mohsen Kamal El-Sagheir, Mohammed E. Draz, Niveen A. Mohamed and Ahmed Safwat Aboraia Tags: Research Source Type: research
Multimodal Imaging of a Case of Bilateral Frosted Branch Angiitis in a 5-Year-Old Boy Secondary to Epstein Barr Virus (EBV) Infection
CONCLUSIONS: Frosted branch angiitis can present following an EBV infection.PMID:37071816 | DOI:10.1080/09273948.2023.2194412 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 18, 2023 Category: Allergy & Immunology Authors: Raunaq Khanna Chitralekha S Devishanmani Suchitra Pradeep Jyotirmay Biswas Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
Bell Palsy: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):415-420.ABSTRACTBell palsy should be suspected in patients with acute onset of unilateral facial weakness or paralysis involving the forehead in the absence of other neurologic abnormalities. The overall prognosis is good. More than two-thirds of patients with typical Bell palsy have a complete spontaneous recovery. For children and pregnant women, the rate of complete recovery is up to 90%. Bell palsy is idiopathic. Laboratory testing and imaging are not required for diagnosis. When other causes of facial weakness are being considered, laboratory testing may identify a treatable cause. An...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Sarah N Dalrymple Jessica H Row John Gazewood Source Type: research
