Distal Pancreatectomy for Body Pancreatic Ductal Adenocarcinoma: Is Splenectomy Necessary? A Propensity Score Matched Study
CONCLUSION: SPDP for B-PDAC is associated with less postoperative morbidity than DSP, without impairing oncological outcomes.PMID:38526834 | DOI:10.1245/s10434-024-15220-0 (Source: Ann Oncol)
Source: Ann Oncol - March 25, 2024 Category: Cancer & Oncology Authors: Tatiana Codjia Christian Hobeika Pierre Platevoet Riccardo Pravisani Safi Dokmak B éatrice Aussilhou Lancelot Marique J érome Cros Fran çois Cauchy Mickael Lesurtel Alain Sauvanet Source Type: research
Hippocampal HDAC6 promotes POCD by regulating NLRP3-induced microglia pyroptosis via HSP90/HSP70 in aged mice
CONCLUSIONS: Our findings suggest that hippocampal HDAC6 promotes POCD by regulating NLRP3-induced microglia pyroptosis via HSP90/HSP70 in aged mice.PMID:38527593 | DOI:10.1016/j.bbadis.2024.167137 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - March 25, 2024 Category: Biochemistry Authors: Qi-Cheng Lin Jiao Wang Xin-Lin Wang Chi Pan Shao-Wu Jin Steven Char Yuan-Xiang Tao Hong Cao Jun Li Source Type: research
Diagnosis and comprehensive treatment of a glucagonoma in a patient with residual intrahepatic metastases postoperatively: A case report and literature review
Oncol Lett. 2024 Mar 11;27(5):202. doi: 10.3892/ol.2024.14336. eCollection 2024 May.ABSTRACTGlucagonomas are rare neuroendocrine neoplasms of the pancreas with malignant potential. At present, their epidemiology is not entirely clear, so clinicians are not well versed, lacking any consensus on diagnosis or comprehensive treatment. The present study reports the case of a 32-year-old woman hospitalized for recurrent glossitis, perioral dermatitis and necrolytic migratory erythema (NME) of both lower limbs. Imaging studies revealed a low-density nodule (~2 cm) in the tail of the pancreas, as well as multiple space-occupying h...
Source: Oncology Letters - March 22, 2024 Category: Cancer & Oncology Authors: Shenghui Yu Muxi Ge Cheng Zhang Lang Chen Lei Zhao Source Type: research
[ < sup > 18 < /sup > F]FDOPA PET/CT in Solid Pseudopapillary Tumor of the Pancreas: a Recurred Tumor Mimicking Splenosis
Nucl Med Mol Imaging. 2024 Apr;58(2):81-85. doi: 10.1007/s13139-023-00826-1. Epub 2023 Oct 5.ABSTRACTSolid pseudopapillary tumor (SPT) of the pancreas is a neoplasm with low malignant potential. It is often challenging to diagnose SPT due to its nonspecific clinical and radiological features, and [18F]FDOPA is effective in diagnosing SPT, particularly in differentiating SPT from benign conditions such as splenosis. A 55-year-old woman underwent distal pancreatectomy and splenectomy for histologically confirmed SPT. She was also initially diagnosed with splenosis. During follow-up, sizes of multiple nodular lesions were inc...
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Joonhyung Gil Minseok Suh Hongyoon Choi Jin Chul Paeng Gi Jeong Cheon Keon Wook Kang Source Type: research
[ < sup > 18 < /sup > F]FDOPA PET/CT in Solid Pseudopapillary Tumor of the Pancreas: a Recurred Tumor Mimicking Splenosis
Nucl Med Mol Imaging. 2024 Apr;58(2):81-85. doi: 10.1007/s13139-023-00826-1. Epub 2023 Oct 5.ABSTRACTSolid pseudopapillary tumor (SPT) of the pancreas is a neoplasm with low malignant potential. It is often challenging to diagnose SPT due to its nonspecific clinical and radiological features, and [18F]FDOPA is effective in diagnosing SPT, particularly in differentiating SPT from benign conditions such as splenosis. A 55-year-old woman underwent distal pancreatectomy and splenectomy for histologically confirmed SPT. She was also initially diagnosed with splenosis. During follow-up, sizes of multiple nodular lesions were inc...
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Joonhyung Gil Minseok Suh Hongyoon Choi Jin Chul Paeng Gi Jeong Cheon Keon Wook Kang Source Type: research
Splenectomy is Associated With More Complications Than Spleen Preservation in Patients With Blunt Abdominal Trauma
The spleen is involved in almost 32% of abdominal trauma. In recent years, the substitution of the surgical treatment of blunt splenic injury with a nonoperative management in selected cases has occurred. The aim of this study is to compare the group of patients undergoing splenectomy with conservative treatment and embolization when necessary. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Gustavo Kleinsorge, Rodrigo do Lago, Daniel Pinto Source Type: research
Two cases of venous thromboembolism in siblings after splenectomy due to a novel PROC gene mutation
Venous thromboembolism(VTE)is a common multifactorial disease. Anticoagulant protein deficiency is the most usual hereditary thrombophilia in the Chinese people, which includes protein C(PC), protein S and ant... (Source: Thrombosis Journal)
Source: Thrombosis Journal - March 19, 2024 Category: Hematology Authors: Yunfang Zhang, Bo Wang, Yuxin Bai and Anxin Wang Tags: Case Report Source Type: research
Predictors of portal vein thrombosis after splenectomy in patients with cirrhosis
CONCLUSION: Wider PVD and MELD score > 10 were independent predictors of PVT at 1 months, 3 months, and 12 months after splenectomy in patient with cirrhosis.PMID:38495270 | PMC:PMC10941749 | DOI:10.4254/wjh.v16.i2.241 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - March 18, 2024 Category: Gastroenterology Authors: Ting Li Li-Li Wang Ya-Ping Li Jian Gan Xi-Sheng Wei Xiao-Rong Mao Jun-Feng Li Source Type: research
