Addressing thrombosis concerns in immune thrombocytopenia: the role of fostamatinib in immune thrombocytopenia management
Expert Rev Hematol. 2024 Jan-Mar;17(1-3):55-66. doi: 10.1080/17474086.2024.2318345. Epub 2024 Feb 19.ABSTRACTINTRODUCTION: Immune thrombocytopenia (ITP), a disease that commonly presents with an increased risk of bleeding, can also paradoxically produce an increased risk of thromboembolic events. The risk of thromboembolism can be associated with patient-related factors (e.g. co-morbidities, age and history of thrombosis), disease-related factors (e.g. a greater proportion of younger, more reactive platelets, and the presence of microparticles and pro-inflammatory cytokines) and treatment-related factors (e.g. splenectomy,...
Source: Expert Review of Hematology - February 19, 2024 Category: Hematology Authors: Drew Provan Jecko Thachil Mar ía Teresa Álvarez Román Source Type: research
Splenectomy at Early stage of Autoimmune Arthritis Delayed Inflammatory Response and Reduced Joint Deterioration in Mice
In conclusion, splenectomy in early stages of GIA delayed the inflammatory response, suggesting a protective effect against the development and progression of severe destructive arthritis.PMID:38363980 | DOI:10.1093/cei/uxae013 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Esam Khanfar Katalin Olasz Szonja G ál Erzs ébet Gajdócsi B éla Kajtár Tam ás Kiss P éter Balogh Timea Berki Ferenc Boldizs ár Source Type: research
Splenectomy at Early stage of Autoimmune Arthritis Delayed Inflammatory Response and Reduced Joint Deterioration in Mice
In conclusion, splenectomy in early stages of GIA delayed the inflammatory response, suggesting a protective effect against the development and progression of severe destructive arthritis.PMID:38363980 | DOI:10.1093/cei/uxae013 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Esam Khanfar Katalin Olasz Szonja G ál Erzs ébet Gajdócsi B éla Kajtár Tam ás Kiss P éter Balogh Timea Berki Ferenc Boldizs ár Source Type: research
Splenectomy at Early stage of Autoimmune Arthritis Delayed Inflammatory Response and Reduced Joint Deterioration in Mice
In conclusion, splenectomy in early stages of GIA delayed the inflammatory response, suggesting a protective effect against the development and progression of severe destructive arthritis.PMID:38363980 | DOI:10.1093/cei/uxae013 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Esam Khanfar Katalin Olasz Szonja G ál Erzs ébet Gajdócsi B éla Kajtár Tam ás Kiss P éter Balogh Timea Berki Ferenc Boldizs ár Source Type: research
Splenectomy at Early stage of Autoimmune Arthritis Delayed Inflammatory Response and Reduced Joint Deterioration in Mice
In conclusion, splenectomy in early stages of GIA delayed the inflammatory response, suggesting a protective effect against the development and progression of severe destructive arthritis.PMID:38363980 | DOI:10.1093/cei/uxae013 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Esam Khanfar Katalin Olasz Szonja G ál Erzs ébet Gajdócsi B éla Kajtár Tam ás Kiss P éter Balogh Timea Berki Ferenc Boldizs ár Source Type: research
Splenectomy at Early stage of Autoimmune Arthritis Delayed Inflammatory Response and Reduced Joint Deterioration in Mice
In conclusion, splenectomy in early stages of GIA delayed the inflammatory response, suggesting a protective effect against the development and progression of severe destructive arthritis.PMID:38363980 | DOI:10.1093/cei/uxae013 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Esam Khanfar Katalin Olasz Szonja G ál Erzs ébet Gajdócsi B éla Kajtár Tam ás Kiss P éter Balogh Timea Berki Ferenc Boldizs ár Source Type: research
Clinicopathological analysis of sclerosing angiomatoid nodular transformation in the spleen
CONCLUSION: The diagnosis of SANT requires a combination of immunohistochemical and histological features, and early splenectomy is crucial for treatment.PMID:38358197 | DOI:10.4103/ijpm.ijpm_543_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 15, 2024 Category: Pathology Authors: Shufei Wei Yongliang Han Yingyong Hou Liangliang Wang Source Type: research
Clinicopathological analysis of sclerosing angiomatoid nodular transformation in the spleen
CONCLUSION: The diagnosis of SANT requires a combination of immunohistochemical and histological features, and early splenectomy is crucial for treatment.PMID:38358197 | DOI:10.4103/ijpm.ijpm_543_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 15, 2024 Category: Pathology Authors: Shufei Wei Yongliang Han Yingyong Hou Liangliang Wang Source Type: research
Cancers, Vol. 16, Pages 790: Splenectomy as Part of Maximal-Effort Cytoreductive Surgery in Advanced Epithelial Ovarian Cancer
Discussion: The findings of our study support the feasibility of splenectomy in advanced epithelial ovarian cancer; however, its impact on patients’ survival is considerable. Therefore, every effort should be made to avoid splenic injury which will result in unintended splenectomy for non-oncological reasons. (Source: Cancers)
Source: Cancers - February 15, 2024 Category: Cancer & Oncology Authors: Vasilios Pergialiotis Eleftherios Zachariou Vasilios Lygizos Dimitrios Efthymios Vlachos Emmanouil Stamatakis Kyveli Angelou Georgios Daskalakis Nikolaos Thomakos Dimitrios Haidopoulos Tags: Article Source Type: research
