Electroacupuncture alleviates intestinal inflammation via a distinct neuro-immune signal pathway in the treatment of postoperative ileus
CONCLUSIONS: EA at ST36 prevents intestinal inflammation and dysmotility through a neural circuit that requires vagal innervation but is independent of the spleen. Further findings revealed that the process involves enteric neurons mediating the vagal signal and requires the presence of α7nAChR. These findings suggest that utilizing EA at ST36 may represent a possible therapeutic approach for POI and other immune-related gastrointestinal diseases.PMID:38471276 | DOI:10.1016/j.biopha.2024.116387 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - March 12, 2024 Category: Drugs & Pharmacology Authors: Shuchang Liu Wei Fu Jingnan Fu Guibing Chen Yuxin He Ting Zheng Tao Ma Source Type: research
Electroacupuncture alleviates intestinal inflammation via a distinct neuro-immune signal pathway in the treatment of postoperative ileus
CONCLUSIONS: EA at ST36 prevents intestinal inflammation and dysmotility through a neural circuit that requires vagal innervation but is independent of the spleen. Further findings revealed that the process involves enteric neurons mediating the vagal signal and requires the presence of α7nAChR. These findings suggest that utilizing EA at ST36 may represent a possible therapeutic approach for POI and other immune-related gastrointestinal diseases.PMID:38471276 | DOI:10.1016/j.biopha.2024.116387 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - March 12, 2024 Category: Drugs & Pharmacology Authors: Shuchang Liu Wei Fu Jingnan Fu Guibing Chen Yuxin He Ting Zheng Tao Ma Source Type: research
Primary Immune Thrombocytopenic Purpura (ITP) and ITP Associated with Systemic Lupus Erythematosus: A Review of Clinical Characteristics and Treatment Modalities
Int J Rheumatol. 2024 Mar 1;2024:6650921. doi: 10.1155/2024/6650921. eCollection 2024.ABSTRACTImmune thrombocytopenic purpura (ITP) is an immune-mediated disorder characterized by the destruction of platelets and megakaryocytes due to autoantibodies against the platelet surface proteins. ITP without any apparent cause of thrombocytopenia is defined as primary ITP, and ITP in the setting of SLE is secondary ITP, which can be diagnosed after excluding other causes of thrombocytopenia by history, physical examination, and laboratory testing. Patients with ITP associated with SLE have higher median platelet count and less blee...
Source: International Journal of Rheumatology - March 11, 2024 Category: Rheumatology Authors: Krishna Prasad Bashyal Sangam Shah Calvin Ghimire Shravya Balmuri Pradip Chaudhary Sandip Karki Anuj Krishna Poudel Ashbina Pokharel Vishal Devarkonda Samina Hayat Source Type: research
Hereditary spherocytosis in a young female in Eastern Nepal: a case report
CONCLUSION: HS remains underdiagnosed, especially in our regions. The osmotic fragility test emerges as an economical diagnostic tool in resource-limited settings, particularly when spherocytosis is absent in the peripheral blood smears. Its inclusion in diagnostic protocols can expedite accurate HS identification and enhance patient outcomes.PMID:38463107 | PMC:PMC10923321 | DOI:10.1097/MS9.0000000000001804 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Anusha Rayamajhi Manisha Shrestha Priyanka K C Robin Maskey Source Type: research
A rare delayed onset of esophageal varices and portal vein thrombosis in a ten-year-old patient following umbilical vein catheterization
CONCLUSION: This case highlights pediatric PVT, emphasizing the need for a collaborative approach among gastroenterologists, hematologists, and geneticists. Further research is required to understand PVT mechanisms and long-term implications, aiding in diagnosis and management, especially when it appears in late childhood. Evaluation is crucial in deciphering thrombophilia-related complications in the context of hypertension.PMID:38463113 | PMC:PMC10923273 | DOI:10.1097/MS9.0000000000001588 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Qusay Abdoh Abdalaziz Darwish Mohammad Alnees Mahdi Awwad Duha Najajra Mai Alsadi Maysa Alawneh Source Type: research
Primary Immune Thrombocytopenic Purpura (ITP) and ITP Associated with Systemic Lupus Erythematosus: A Review of Clinical Characteristics and Treatment Modalities
Int J Rheumatol. 2024 Mar 1;2024:6650921. doi: 10.1155/2024/6650921. eCollection 2024.ABSTRACTImmune thrombocytopenic purpura (ITP) is an immune-mediated disorder characterized by the destruction of platelets and megakaryocytes due to autoantibodies against the platelet surface proteins. ITP without any apparent cause of thrombocytopenia is defined as primary ITP, and ITP in the setting of SLE is secondary ITP, which can be diagnosed after excluding other causes of thrombocytopenia by history, physical examination, and laboratory testing. Patients with ITP associated with SLE have higher median platelet count and less blee...
Source: International Journal of Rheumatology - March 11, 2024 Category: Rheumatology Authors: Krishna Prasad Bashyal Sangam Shah Calvin Ghimire Shravya Balmuri Pradip Chaudhary Sandip Karki Anuj Krishna Poudel Ashbina Pokharel Vishal Devarkonda Samina Hayat Source Type: research
Hereditary spherocytosis in a young female in Eastern Nepal: a case report
CONCLUSION: HS remains underdiagnosed, especially in our regions. The osmotic fragility test emerges as an economical diagnostic tool in resource-limited settings, particularly when spherocytosis is absent in the peripheral blood smears. Its inclusion in diagnostic protocols can expedite accurate HS identification and enhance patient outcomes.PMID:38463107 | PMC:PMC10923321 | DOI:10.1097/MS9.0000000000001804 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Anusha Rayamajhi Manisha Shrestha Priyanka K C Robin Maskey Source Type: research
A rare delayed onset of esophageal varices and portal vein thrombosis in a ten-year-old patient following umbilical vein catheterization
CONCLUSION: This case highlights pediatric PVT, emphasizing the need for a collaborative approach among gastroenterologists, hematologists, and geneticists. Further research is required to understand PVT mechanisms and long-term implications, aiding in diagnosis and management, especially when it appears in late childhood. Evaluation is crucial in deciphering thrombophilia-related complications in the context of hypertension.PMID:38463113 | PMC:PMC10923273 | DOI:10.1097/MS9.0000000000001588 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Qusay Abdoh Abdalaziz Darwish Mohammad Alnees Mahdi Awwad Duha Najajra Mai Alsadi Maysa Alawneh Source Type: research
Primary Immune Thrombocytopenic Purpura (ITP) and ITP Associated with Systemic Lupus Erythematosus: A Review of Clinical Characteristics and Treatment Modalities
Int J Rheumatol. 2024 Mar 1;2024:6650921. doi: 10.1155/2024/6650921. eCollection 2024.ABSTRACTImmune thrombocytopenic purpura (ITP) is an immune-mediated disorder characterized by the destruction of platelets and megakaryocytes due to autoantibodies against the platelet surface proteins. ITP without any apparent cause of thrombocytopenia is defined as primary ITP, and ITP in the setting of SLE is secondary ITP, which can be diagnosed after excluding other causes of thrombocytopenia by history, physical examination, and laboratory testing. Patients with ITP associated with SLE have higher median platelet count and less blee...
Source: International Journal of Rheumatology - March 11, 2024 Category: Rheumatology Authors: Krishna Prasad Bashyal Sangam Shah Calvin Ghimire Shravya Balmuri Pradip Chaudhary Sandip Karki Anuj Krishna Poudel Ashbina Pokharel Vishal Devarkonda Samina Hayat Source Type: research
