Hippocampal HDAC6 promotes POCD by regulating NLRP3-induced microglia pyroptosis via HSP90/HSP70 in aged mice

CONCLUSIONS: Our findings suggest that hippocampal HDAC6 promotes POCD by regulating NLRP3-induced microglia pyroptosis via HSP90/HSP70 in aged mice.PMID:38527593 | DOI:10.1016/j.bbadis.2024.167137

Source: Biochimica et Biophysica Acta - March 25, 2024 Category: Biochemistry Authors: Qi-Cheng Lin Jiao Wang Xin-Lin Wang Chi Pan Shao-Wu Jin Steven Char Yuan-Xiang Tao Hong Cao Jun Li Source Type: research