Preparation and characterization of NaF/Chitosan supramolecular complex and their effects on prevention of enamel demineralization
J Mech Behav Biomed Mater. 2023 Sep 19;147:106134. doi: 10.1016/j.jmbbm.2023.106134. Online ahead of print.ABSTRACTFluoridated mouthrinse is indicated for individuals with high risk of caries. Chitosan (Chit) exhibits antibacterial properties, but little is known about its effects on enamel when combined with sodium fluoride (NaF) to form NaF/Chit supramolecular complexes. In our study, NaF/Chit supramolecular complexes structured as microparticles were synthetized and characterized, and their effects on human enamel were evaluated after cariogenic challenge simulating the daily mouthrinse use. Initially, NaF/Chit complex ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - September 24, 2023 Category: Materials Science Authors: Alana Gail Lopes Ta ís Chaves Magalhães Ângelo Márcio Leite Denadai Hugo Lemes Carlo Rog ério Lacerda Dos Santos Eliseu Aldrighi Munchow Fab íola Galbiatti de Carvalho Source Type: research
Preparation and characterization of NaF/Chitosan supramolecular complex and their effects on prevention of enamel demineralization
J Mech Behav Biomed Mater. 2023 Sep 19;147:106134. doi: 10.1016/j.jmbbm.2023.106134. Online ahead of print.ABSTRACTFluoridated mouthrinse is indicated for individuals with high risk of caries. Chitosan (Chit) exhibits antibacterial properties, but little is known about its effects on enamel when combined with sodium fluoride (NaF) to form NaF/Chit supramolecular complexes. In our study, NaF/Chit supramolecular complexes structured as microparticles were synthetized and characterized, and their effects on human enamel were evaluated after cariogenic challenge simulating the daily mouthrinse use. Initially, NaF/Chit complex ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - September 24, 2023 Category: Materials Science Authors: Alana Gail Lopes Ta ís Chaves Magalhães Ângelo Márcio Leite Denadai Hugo Lemes Carlo Rog ério Lacerda Dos Santos Eliseu Aldrighi Munchow Fab íola Galbiatti de Carvalho Source Type: research
Effects of sodium fluoride on neural tube development in chick embryos
CONCLUSION: Low and high-dose fluoride exposure was associated with developing neural tube defects, but there was no statisticaly significance.PMID:37741361 | DOI:10.1016/j.neuchi.2023.101502 (Source: Neuro-Chirurgie)
Source: Neuro-Chirurgie - September 23, 2023 Category: Neurosurgery Authors: Mazhar Mammadov Selin Tural Emon Ezgi Akar Dilek Akakin Dila Şener Source Type: research
Effects of sodium fluoride on neural tube development in chick embryos
CONCLUSION: Low and high-dose fluoride exposure was associated with developing neural tube defects, but there was no statisticaly significance.PMID:37741361 | DOI:10.1016/j.neuchi.2023.101502 (Source: Neurochirurgie)
Source: Neurochirurgie - September 23, 2023 Category: Neurosurgery Authors: Mazhar Mammadov Selin Tural Emon Ezgi Akar Dilek Akakin Dila Şener Source Type: research
Effects of sodium fluoride on neural tube development in chick embryos
CONCLUSION: Low and high-dose fluoride exposure was associated with developing neural tube defects, but there was no statisticaly significance.PMID:37741361 | DOI:10.1016/j.neuchi.2023.101502 (Source: Neuro-Chirurgie)
Source: Neuro-Chirurgie - September 23, 2023 Category: Neurosurgery Authors: Mazhar Mammadov Selin Tural Emon Ezgi Akar Dilek Akakin Dila Şener Source Type: research
Effects of sodium fluoride on neural tube development in chick embryos
CONCLUSION: Low and high-dose fluoride exposure was associated with developing neural tube defects, but there was no statisticaly significance.PMID:37741361 | DOI:10.1016/j.neuchi.2023.101502 (Source: Neurochirurgie)
Source: Neurochirurgie - September 23, 2023 Category: Neurosurgery Authors: Mazhar Mammadov Selin Tural Emon Ezgi Akar Dilek Akakin Dila Şener Source Type: research
Novel technique of detecting inflammatory and osseous changes in the glenohumeral joint associated with patient age and weight using FDG- and NaF-PET imaging
CONCLUSION: Our study demonstrates the varying effect of limb laterality and BMI on FDG and NaF uptake at the GH joint. Adoption of molecular imaging will require future studies that correlate tracer uptake with relevant medical and illness history as well as degenerative change evident on traditional imaging.PMID:37736491 | PMC:PMC10509288 (Source: Molecular Medicine)
Source: Molecular Medicine - September 22, 2023 Category: Molecular Biology Authors: Peter Sang Uk Park Lori Jia William Y Raynor Om H Gandhi Mia Mijung Park Thomas J Werner Poul Flemming H øilund-Carlsen Abass Alavi Source Type: research
Regulatory-systemic approach in Aspergillus niger for bioleaching improvement by controlling precipitation
Appl Microbiol Biotechnol. 2023 Sep 22. doi: 10.1007/s00253-023-12776-x. Online ahead of print.ABSTRACTIn the context of e-waste recycling by fungal bioleaching, nickel and cobalt precipitate as toxic metals by oxalic acid, whereas organic acids, such as citric, act as a high-performance chelating agent in dissolving these metals. Oxalic acid elimination requires an excess and uneconomical carbon source concentration in culture media. To resolve this issue, a novel and straightforward systems metabolic engineering method was devised to switch metabolic flux from oxalic acid to citric acid. In this technique, the genome-sca...
Source: Applied Microbiology and Biotechnology - September 22, 2023 Category: Microbiology Authors: Ali Naderi Farzane Vakilchap Ehsan Motamedian Seyyed Mohammad Mousavi Source Type: research
Novel technique of detecting inflammatory and osseous changes in the glenohumeral joint associated with patient age and weight using FDG- and NaF-PET imaging
CONCLUSION: Our study demonstrates the varying effect of limb laterality and BMI on FDG and NaF uptake at the GH joint. Adoption of molecular imaging will require future studies that correlate tracer uptake with relevant medical and illness history as well as degenerative change evident on traditional imaging.PMID:37736491 | PMC:PMC10509288 (Source: Molecular Medicine)
Source: Molecular Medicine - September 22, 2023 Category: Molecular Biology Authors: Peter Sang Uk Park Lori Jia William Y Raynor Om H Gandhi Mia Mijung Park Thomas J Werner Poul Flemming H øilund-Carlsen Abass Alavi Source Type: research
Regulatory-systemic approach in Aspergillus niger for bioleaching improvement by controlling precipitation
Appl Microbiol Biotechnol. 2023 Sep 22. doi: 10.1007/s00253-023-12776-x. Online ahead of print.ABSTRACTIn the context of e-waste recycling by fungal bioleaching, nickel and cobalt precipitate as toxic metals by oxalic acid, whereas organic acids, such as citric, act as a high-performance chelating agent in dissolving these metals. Oxalic acid elimination requires an excess and uneconomical carbon source concentration in culture media. To resolve this issue, a novel and straightforward systems metabolic engineering method was devised to switch metabolic flux from oxalic acid to citric acid. In this technique, the genome-sca...
Source: Applied Microbiology and Biotechnology - September 22, 2023 Category: Microbiology Authors: Ali Naderi Farzane Vakilchap Ehsan Motamedian Seyyed Mohammad Mousavi Source Type: research
Combined Effects of Fluoride and Dietary Seleno-L-methionine at Environmentally Relevant Concentrations on Female Zebrafish (Danio rerio) Liver: Histopathological Damages, Oxidative Stress and Inflammation
In this study, female zebrafish (Danio rerio) were exposed to fluoride (80 mg/L sodium fluoride) and/or dietary selenomethionine for 30, 60 and 90 days, the effects on the liver of zebrafish were investigated. The results indicated that an increase in fluoride burden, inhibited growth and impaired liver morphology were recorded after fluoride exposure. Furthermore, fluoride alone caused oxidative stress and inflammation in the liver, as reflected by the increase in ROS and MDA contents, the reduction of anti-oxidative enzymes, the altered immune related enzymes (ACP, AKP, LZM and MPO) and the expression of IL-6, IL-1β, TN...
Source: Biological Trace Element Research - September 20, 2023 Category: Biology Authors: Xiulin Zhang Jinling Cao Jianjie Chen Guodong Wang Lijuan Li Xiaobing Wei Runxiao Zhang Source Type: research
Effects of prolonged fluoride exposure on innate immunity, intestinal mechanical, and immune barriers in mice
Res Vet Sci. 2023 Sep 14;164:105019. doi: 10.1016/j.rvsc.2023.105019. Online ahead of print.ABSTRACTThe aim of this study is to explore the effects of fluoride on the innate immunity, intestinal mechanical barrier, and immune barrier of C57BL/6 mice, as well as to analyze the degree of structural and tissue damage, providing reference data for related research. Mice were randomly divided into four groups and then treated with 0 mg/L (control), 50 mg/L, 100 mg/L, 125 mg/L sodium fluoride solution, respectively, for 120 days. Histological technique, ELISA, MTT colorimetry methods were used to detect and analyze the effects o...
Source: Cell Research - September 20, 2023 Category: Cytology Authors: Yan Wang Jing Xu Hang Chen Yuanbin Shu Weiqi Peng Chunxiao Lai Ruiyang Kong Ruiyang Lan Lijing Huang Jinge Xin Ning Sun Xueqin Ni Yang Bai Bangyuan Wu Source Type: research
Combined Effects of Fluoride and Dietary Seleno-L-methionine at Environmentally Relevant Concentrations on Female Zebrafish (Danio rerio) Liver: Histopathological Damages, Oxidative Stress and Inflammation
In this study, female zebrafish (Danio rerio) were exposed to fluoride (80 mg/L sodium fluoride) and/or dietary selenomethionine for 30, 60 and 90 days, the effects on the liver of zebrafish were investigated. The results indicated that an increase in fluoride burden, inhibited growth and impaired liver morphology were recorded after fluoride exposure. Furthermore, fluoride alone caused oxidative stress and inflammation in the liver, as reflected by the increase in ROS and MDA contents, the reduction of anti-oxidative enzymes, the altered immune related enzymes (ACP, AKP, LZM and MPO) and the expression of IL-6, IL-1β, TN...
Source: Biological Trace Element Research - September 20, 2023 Category: Biology Authors: Xiulin Zhang Jinling Cao Jianjie Chen Guodong Wang Lijuan Li Xiaobing Wei Runxiao Zhang Source Type: research
Utility of a simplified [18F] sodium fluoride PET imaging method to quantify bone metabolic flux for a wide range of clinical applications
We review the rationale, methodology, and clinical utility of quantitative [18F] sodium fluoride ([18F]NaF) positron emission tomography-computed tomography (PET-CT) imaging to measure bone metabolic flux (Ki, also known as bone plasma clearance), a measurement indicative of the local rate of bone formation at the chosen region of interest. We review the bone remodelling cycle and explain what aspects of bone remodelling are addressed by [18F]NaF PET-CT. We explain how the technique works, what measurements are involved, and what makes [18F]NaF PET-CT a useful tool for the study of bone remodelling. We discuss how these me...
Source: Frontiers in Endocrinology - September 13, 2023 Category: Endocrinology Source Type: research
Cardioprotective and renoprotective effects of melatonin and vitamin E on fluoride-induced hypertension and renal dysfunction in rats
AbstractFluoride is an important toxicological and environmental toxicant that is implicated in diverse cardiorenal system dysfunctions via the induction of oxidative stress. The present study aims at evaluating the cardioprotective and renoprotective effects of melatonin and vitamin E on fluoride toxicity on biomarkers of oxidative stress, clinical pathology, and their molecular mechanism of action. Apparently healthy male rats of the Wistar strain (n = 50; 160 ± 7.5 g), were randomly distributed into five groups of ten animals per group as follows: Control, sodium fluoride (NaF, 25 mg/kg), NaF and melatonin 20...
Source: Comparative Clinical Pathology - September 13, 2023 Category: Pathology Source Type: research
