In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution
Braz Dent J. 2023 May-Jun;34(3):119-128. doi: 10.1590/0103-6440202305460.ABSTRACTTo assess the in vitro and in situ effect of experimental combined fluoride and calcium nanocomposite solutions on dental caries prevention. Nanocompound mesoporous silica (MS) with calcium (Ca) and sodium fluoride (NaF) - (MSCaNaF); MS with NaF (MSNaF), NaF solution (positive control), and deionized water (negative control - CG) were studied. The specimens (n=130) were submitted in vitro to a multispecies biofilm in the presence of 2% sucrose. After 24 h and 48 h, the culture medium pH, the percent of surface mineral loss (%SML), and lesion d...
Source: Braz Dent J - July 19, 2023 Category: Dentistry Authors: Karla Lorene de Fran ça Leite Mariana Leonel Martins Millene de Oliveira Dias Fernanda Oliveira Miranda Tavares Isabella Barbosa Dos Santos Justino L úcio Mendes Cabral Aline de Almeida Neves Yuri Wanderley Cavalcanti Lucianne Cople Maia Source Type: research

The role of FGF9-mediated TGF- β1/Smad signaling in enamel hypoplasia induced by exposure to fluoride and SO < sub > 2 < /sub > in rats
Ecotoxicol Environ Saf. 2023 Jul 14;263:115243. doi: 10.1016/j.ecoenv.2023.115243. Online ahead of print.ABSTRACTMany geographical areas of the world are polluted by both fluoride and sulfur dioxide (SO2). However, the effects of simultaneous exposure to fluoride and SO2 on teeth are unknown. Fibroblast growth factor-9 (FGF9) and transforming growth factor-β1 (TGF-β1) are key signaling molecules in enamel development. The purpose of the study was to explore the effects of co-exposure to fluoride and sulfur dioxide on enamel and to investigate the role and mechanism of FGF9 and TGF-β1. First, sodium fluoride (NaF) and SO...
Source: Ecotoxicology and Environmental Safety - July 16, 2023 Category: Environmental Health Authors: Ying Lv Yang Wang Jin Yao Jiaojiao He Changhu Lin Guohui Bai Chenglong Tu Source Type: research

The role of FGF9-mediated TGF- β1/Smad signaling in enamel hypoplasia induced by exposure to fluoride and SO < sub > 2 < /sub > in rats
Ecotoxicol Environ Saf. 2023 Jul 14;263:115243. doi: 10.1016/j.ecoenv.2023.115243. Online ahead of print.ABSTRACTMany geographical areas of the world are polluted by both fluoride and sulfur dioxide (SO2). However, the effects of simultaneous exposure to fluoride and SO2 on teeth are unknown. Fibroblast growth factor-9 (FGF9) and transforming growth factor-β1 (TGF-β1) are key signaling molecules in enamel development. The purpose of the study was to explore the effects of co-exposure to fluoride and sulfur dioxide on enamel and to investigate the role and mechanism of FGF9 and TGF-β1. First, sodium fluoride (NaF) and SO...
Source: Ecotoxicology and Environmental Safety - July 16, 2023 Category: Environmental Health Authors: Ying Lv Yang Wang Jin Yao Jiaojiao He Changhu Lin Guohui Bai Chenglong Tu Source Type: research

ERS Mediated by GRP-78/PERK/CHOP Signaling Is Involved in Fluoride-Induced Ameloblast Apoptosis
This study presents a possibility for therapeutic strategies for dental fluorosis, while further exploration is required.PMID:37410266 | DOI:10.1007/s12011-023-03746-5 (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - July 6, 2023 Category: Biology Authors: Li Jinyi Yang Keyu Dai Shanshan He Shuyang Liu Ruirui Guo Qingyu Liu Fei Source Type: research

ERS Mediated by GRP-78/PERK/CHOP Signaling Is Involved in Fluoride-Induced Ameloblast Apoptosis
This study presents a possibility for therapeutic strategies for dental fluorosis, while further exploration is required.PMID:37410266 | DOI:10.1007/s12011-023-03746-5 (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - July 6, 2023 Category: Biology Authors: Li Jinyi Yang Keyu Dai Shanshan He Shuyang Liu Ruirui Guo Qingyu Liu Fei Source Type: research