Efficacy of Different Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth
Conclusions: Ultimately, with both fluoride therapies reducing hypersensitivity/pain significantly, treatment with 38% SDF+KI was clearly more effective in caries arrest than 5% NaF varnish after a 3-month period.PMID:38004091 | PMC:PMC10672976 | DOI:10.3390/medicina59112042 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - November 25, 2023 Category: Universities & Medical Training Authors: Mohamed Abudrya Christian H Splieth Mhd Said Mourad Ruth M Santamar ía Source Type: research

Effects of silver diamine fluoride on demineralization protection after a secondary acid challenge
CONCLUSIONS: Using silver diamine fluoride may have comparable benefits to fluoride varnish in mineral loss prevention.PMID:37937621 | DOI:10.1590/1678-7757-2023-0244 (Source: Appl Human Sci)
Source: Appl Human Sci - November 8, 2023 Category: Physiology Authors: Mauro A Tudares George J Eckert Frank Lippert Source Type: research

Effects of silver diamine fluoride on demineralization protection after a secondary acid challenge
CONCLUSIONS: Using silver diamine fluoride may have comparable benefits to fluoride varnish in mineral loss prevention.PMID:37937621 | DOI:10.1590/1678-7757-2023-0244 (Source: Appl Human Sci)
Source: Appl Human Sci - November 8, 2023 Category: Physiology Authors: Mauro A Tudares George J Eckert Frank Lippert Source Type: research

Effects of silver diamine fluoride on demineralization protection after a secondary acid challenge
CONCLUSIONS: Using silver diamine fluoride may have comparable benefits to fluoride varnish in mineral loss prevention.PMID:37937621 | DOI:10.1590/1678-7757-2023-0244 (Source: Appl Human Sci)
Source: Appl Human Sci - November 8, 2023 Category: Physiology Authors: Mauro A Tudares George J Eckert Frank Lippert Source Type: research

Aortic valve perivascular adipose tissue computed tomography attenuation in patients with aortic stenosis
CONCLUSIONS: CT-derived aortic valve perivascular adipose tissue attenuation is not associated with AS disease severity, activity or progression suggesting that it has no value in the investigation and management of patients with AS.PMID:37918901 | DOI:10.1136/heartjnl-2023-323217 (Source: Atherosclerosis)
Source: Atherosclerosis - November 2, 2023 Category: Cardiology Authors: Simona B Botezatu Xinming Yu Mohammed N Meah Michelle C Williams Damini Dey David E Newby Evangelos Tzolos Marc R Dweck Source Type: research

Long term stability of lactate in uncentrifuged sodium fluoride/potassium oxalate blood collection tubes
CONCLUSION: A small proportion of lactate specimens may experience significant delay in processing. Although lactate levels may incrementally increase over 48-hours at room temperature in unspun NaF/KOx collection tubes, the changes may not be clinically impactful.PMID:37903217 | DOI:10.1177/00045632231213746 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - October 30, 2023 Category: Biochemistry Authors: Ivan Stevic Jade Bolsover Rick Moore Vipin Bhayana Source Type: research

Long term stability of lactate in uncentrifuged sodium fluoride/potassium oxalate blood collection tubes
CONCLUSION: A small proportion of lactate specimens may experience significant delay in processing. Although lactate levels may incrementally increase over 48-hours at room temperature in unspun NaF/KOx collection tubes, the changes may not be clinically impactful.PMID:37903217 | DOI:10.1177/00045632231213746 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - October 30, 2023 Category: Biochemistry Authors: Ivan Stevic Jade Bolsover Rick Moore Vipin Bhayana Source Type: research

Long term stability of lactate in uncentrifuged sodium fluoride/potassium oxalate blood collection tubes
CONCLUSION: A small proportion of lactate specimens may experience significant delay in processing. Although lactate levels may incrementally increase over 48-hours at room temperature in unspun NaF/KOx collection tubes, the changes may not be clinically impactful.PMID:37903217 | DOI:10.1177/00045632231213746 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - October 30, 2023 Category: Biochemistry Authors: Ivan Stevic Jade Bolsover Rick Moore Vipin Bhayana Source Type: research

Bilateral Carotid Artery Molecular Calcification Assessed by [ < sup > 18 < /sup > F] Fluoride PET/CT: Correlation with Cardiovascular and Thromboembolic Risk Factors
This study utilized positron emission tomography/computed tomography (PET/CT) with [18F] sodium fluoride (NaF) as a tracer to visualize active calcification and inflammation at the molecular level. Our aim was to investigate the association between cardiovascular risk factors and [18F] NaF uptake in the left and right common carotid arteries (LCC and RCC). A cohort of 102 subjects, comprising both at-risk individuals and healthy controls, underwent [18F] NaF PET/CT imaging. The results revealed significant correlations between [18F] NaF uptake and cardiovascular risk factors such as age (β = 0.005, 95% CI 0.003-0.008, p &...
Source: Atherosclerosis - October 28, 2023 Category: Cardiology Authors: Shiv Patil Eric M Teichner Robert C Subtirelu Chitra Parikh Omar Al-Daoud Miraziz Ismoilov Thomas Werner Poul Flemming H øilund-Carlsen Abass Alavi Source Type: research

Bilateral Carotid Artery Molecular Calcification Assessed by [ < sup > 18 < /sup > F] Fluoride PET/CT: Correlation with Cardiovascular and Thromboembolic Risk Factors
This study utilized positron emission tomography/computed tomography (PET/CT) with [18F] sodium fluoride (NaF) as a tracer to visualize active calcification and inflammation at the molecular level. Our aim was to investigate the association between cardiovascular risk factors and [18F] NaF uptake in the left and right common carotid arteries (LCC and RCC). A cohort of 102 subjects, comprising both at-risk individuals and healthy controls, underwent [18F] NaF PET/CT imaging. The results revealed significant correlations between [18F] NaF uptake and cardiovascular risk factors such as age (β = 0.005, 95% CI 0.003-0.008, p &...
Source: Atherosclerosis - October 28, 2023 Category: Cardiology Authors: Shiv Patil Eric M Teichner Robert C Subtirelu Chitra Parikh Omar Al-Daoud Miraziz Ismoilov Thomas Werner Poul Flemming H øilund-Carlsen Abass Alavi Source Type: research

Effects of a stabilized stannous fluoride dentifrice on clinical, immunomodulatory, and microbial outcomes in a human experimental gingivitis model
CONCLUSION: The stannous fluoride stabilized with zinc phosphate dentifrice formulation demonstrated clinical reduction in gingival inflammation and a beneficial effect on microbiome and immune markers. This intervention should be explored as a preventive aid in the progression of plaque-induced gingivitis to periodontitis.PMID:37885337 | DOI:10.1002/JPER.22-0710 (Source: Cancer Control)
Source: Cancer Control - October 27, 2023 Category: Cancer & Oncology Authors: Noah Fine Abdelahhad Barbour Kamini Kaura Kristopher A Kerns Dandan Chen Harsh M Trivedi Juliana Gomez Amarpreet Sabharwal Jeffrey S McLean Richard P Darveau Michael Glogauer Source Type: research

Could imaging microcalcification activity improve abdominal aortic aneurysm risk stratification after intervention?
Calcification is a common feature of abdominal aortic aneurysm (AAA), but its role in the pathogenesis of the disease remains incompletely understood. While heavy arterial macrocalcification is thought be a marker of disease stability, earlier stages in osteogenic remodelling of AAAs marked by microcalcification represent active disease associated with a healing response to inflammation and carry a greater risk of aneurysm expansion. Whether tracking changes in calcification using 18F-sodium fluoride (NaF) positron emission tomography (PET) after therapeutic intervention can improve risk stratification in AAA is the though...
Source: Heart - October 26, 2023 Category: Cardiology Authors: Chowdhury, M. M., Tarkin, J. M. Tags: Editorials Source Type: research

[ < sup > 18 < /sup > F]sodium fluoride positron emission tomography: a systematic bibliometric review from 2008 to 2022
CONCLUSIONS: There has been an increase in the literature published in the field of [18F]NaF PET from 2008 to 2022. The United States holds a prominent position in the field of [18F]NaF PET. Arteriosclerosis and bone metastasis are the main topics in this field and at the forefront of research.PMID:37869342 | PMC:PMC10585531 | DOI:10.21037/qims-23-703 (Source: Atherosclerosis)
Source: Atherosclerosis - October 23, 2023 Category: Cardiology Authors: Weiming Zhou Xiao Liu Yan Li Ting Kang Zhanwen Huang Santao Ou Source Type: research

Identification and characterization of an ectophosphatase activity involved in Acanthamoeba castellanii adhesion to host cells
Eur J Protistol. 2023 Oct 13;91:126026. doi: 10.1016/j.ejop.2023.126026. Online ahead of print.ABSTRACTAcanthamoeba castellanii is a free-living amoeba and an opportunistic pathogen for humans that can cause encephalitis and, more commonly, Acanthamoeba keratitis. During its life cycle, A. castellanii may present as proliferative and infective trophozoites or resistant cysts. The adhesion of trophozoites to host cells is a key first step in the pathogenesis of infection. A major virulence protein of Acanthamoeba is a mannose-binding protein (MBP) that mediates the adhesion of amoebae to cell surfaces. Ectophosphatases are ...
Source: European Journal of Protistology - October 23, 2023 Category: Microbiology Authors: Luiz Fernando Carvalho-Kelly Anita Leocadio Freitas-Mesquita Clara Ferreira Pralon Eduarda de Souza-Maciel Jos é Roberto Meyer-Fernandes Source Type: research

Identification and characterization of an ectophosphatase activity involved in Acanthamoeba castellanii adhesion to host cells
Eur J Protistol. 2023 Oct 13;91:126026. doi: 10.1016/j.ejop.2023.126026. Online ahead of print.ABSTRACTAcanthamoeba castellanii is a free-living amoeba and an opportunistic pathogen for humans that can cause encephalitis and, more commonly, Acanthamoeba keratitis. During its life cycle, A. castellanii may present as proliferative and infective trophozoites or resistant cysts. The adhesion of trophozoites to host cells is a key first step in the pathogenesis of infection. A major virulence protein of Acanthamoeba is a mannose-binding protein (MBP) that mediates the adhesion of amoebae to cell surfaces. Ectophosphatases are ...
Source: European Journal of Protistology - October 23, 2023 Category: Microbiology Authors: Luiz Fernando Carvalho-Kelly Anita Leocadio Freitas-Mesquita Clara Ferreira Pralon Eduarda de Souza-Maciel Jos é Roberto Meyer-Fernandes Source Type: research