Influence of pia-arachnoid complex on the indentation response of porcine brain at different length scales
J Mech Behav Biomed Mater. 2021 Oct 29;127:104925. doi: 10.1016/j.jmbbm.2021.104925. Online ahead of print.ABSTRACTBrain tissues are surrounded by two tightly adhering thin membranes known as the pia-arachnoid complex (PAC), which is pivotal in regulating brain mechanical response upon mechanical impact. Despite the crucial role of PAC as a structural damper protecting the brain, its mechanical contribution has received minimal attention. In this work, the mechanical contribution of PAC on brain tissues against mechanical loading is characterized by using a custom-built indentation apparatus. The indentation responses of t...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 25, 2022 Category: Materials Science Authors: Long Qian Shunbo Wang Shuilong Zhou Yifan Sun Hongwei Zhao Source Type: research

Biodegradation of gelatin stabilized tetragonal zirconia synthesized by microwave assisted sol-gel method
J Mech Behav Biomed Mater. 2022 Jan 7;127:105070. doi: 10.1016/j.jmbbm.2021.105070. Online ahead of print.ABSTRACTThe purpose of current work of is to organize stabilized tetragonal zirconia (t-ZrO2) nano-particles with microwave abetted sol-gel technique. To increase the stability and shrink the crystal size, both microwave (MW) and gelatin components are used as structure guiding methods. Gelatin was used with the aim of bone implantations, as raw materials used in gelatin production are cattle bones. It contains purified collagen protein (a main protein that in the extracellular matrix found in the body's various connec...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 25, 2022 Category: Materials Science Authors: Mahwish Bashir Farzana Majid Summeya Akram Adnan Ali Shaimaa A M Abdelmohsen Source Type: research

Wear investigation based on a novel, anatomic shoulder prosthesis with bearing materials inversion
CONCLUSION: Compared to similarly investigated systems, the Modular-Shoulder-System shows a reduction in wear. This reduction shows that material inversion may lead to a wear reduction. However, if subluxation of the humeral head occurs more frequently, increased material wear can be expected with the Modular-Shoulder-System. An influence of the conformity on the wear behaviour could not be determined.PMID:35074735 | DOI:10.1016/j.jmbbm.2022.105080 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 25, 2022 Category: Materials Science Authors: Maximilian Uhler Steffen Braun Stefan Schroeder Tobias Renkawitz Jan Philippe Kretzer Source Type: research

Flow dynamics in the sinus and downstream of third and fourth generation balloon expandable transcatheter aortic valves
J Mech Behav Biomed Mater. 2022 Jan 17;127:105092. doi: 10.1016/j.jmbbm.2022.105092. Online ahead of print.ABSTRACTOBJECTIVE: The early success of transcatheter aortic valve (TAV) replacement (TAVR) has fueled further innovations in the field leading to the emergence multiple iterations of TAV designs. Whether these newer designs are associated with similar hemodynamic outcomes remains unknown. Recently, the SAPIEN 3 Ultra valve received FDA approval for use in patients with published clinical outcomes. The aim of this study is (1) to evaluate and compare the flow dynamics downstream of the SAPIEN 3 Ultra and a SAPIEN 3 (2...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 23, 2022 Category: Materials Science Authors: Brennan J Vogl Ahmed El Shaer Juan A Crestanello Mohamad Alkhouli Hoda Hatoum Source Type: research

Flow dynamics in the sinus and downstream of third and fourth generation balloon expandable transcatheter aortic valves
J Mech Behav Biomed Mater. 2022 Jan 17;127:105092. doi: 10.1016/j.jmbbm.2022.105092. Online ahead of print.ABSTRACTOBJECTIVE: The early success of transcatheter aortic valve (TAV) replacement (TAVR) has fueled further innovations in the field leading to the emergence multiple iterations of TAV designs. Whether these newer designs are associated with similar hemodynamic outcomes remains unknown. Recently, the SAPIEN 3 Ultra valve received FDA approval for use in patients with published clinical outcomes. The aim of this study is (1) to evaluate and compare the flow dynamics downstream of the SAPIEN 3 Ultra and a SAPIEN 3 (2...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 23, 2022 Category: Materials Science Authors: Brennan J Vogl Ahmed El Shaer Juan A Crestanello Mohamad Alkhouli Hoda Hatoum Source Type: research

Independent changes in bone mineralized and marrow soft tissues following acute knee injury require dual-energy or high-resolution computed tomography for accurate assessment of bone mineral density and stiffness
J Mech Behav Biomed Mater. 2022 Jan 15;127:105091. doi: 10.1016/j.jmbbm.2022.105091. Online ahead of print.ABSTRACTMusculoskeletal injuries often induce local accumulation of blood and/or fluid within the bone marrow, which is detected on medical imaging as edema-like marrow signal intensities (EMSI). In addition to its biological effects on post-injury recovery, the displacement of low-attenuating, largely adipocytic marrow by EMSI may introduce errors into quantitative computed tomography (QCT) measurements of bone mineral density (vBMD) and resulting bone stiffness estimates from image-based finite element (FE) analysis...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 22, 2022 Category: Materials Science Authors: Chantal M J de Bakker Nikolas K Knowles Richard E A Walker Sarah L Manske Steven K Boyd Source Type: research

Independent changes in bone mineralized and marrow soft tissues following acute knee injury require dual-energy or high-resolution computed tomography for accurate assessment of bone mineral density and stiffness
J Mech Behav Biomed Mater. 2022 Jan 15;127:105091. doi: 10.1016/j.jmbbm.2022.105091. Online ahead of print.ABSTRACTMusculoskeletal injuries often induce local accumulation of blood and/or fluid within the bone marrow, which is detected on medical imaging as edema-like marrow signal intensities (EMSI). In addition to its biological effects on post-injury recovery, the displacement of low-attenuating, largely adipocytic marrow by EMSI may introduce errors into quantitative computed tomography (QCT) measurements of bone mineral density (vBMD) and resulting bone stiffness estimates from image-based finite element (FE) analysis...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 22, 2022 Category: Materials Science Authors: Chantal M J de Bakker Nikolas K Knowles Richard E A Walker Sarah L Manske Steven K Boyd Source Type: research

Effect of seasonal change on the biomechanical and physical properties of the human skin
In this study, the effect of one cycle of winter to summer seasonal transition on the mechanical and physical properties of skin was investigated in vivo. Fourteen healthy skin volunteers aged between 22 and 42 years were studied at the volar lower and upper arms. The findings indicate a 22.15% and 34.29% decrease in trans-epidermal water loss (TEWL) and the average epidermal roughness (AER), respectively. Also, improved skin properties were observed such as a 25.48% rise in average epidermal hydration (AEH), 22.59% in skin thickness, 38.64% and 21.92% in melanin and redness, respectively, as well as an 8.25% rise in its f...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 20, 2022 Category: Materials Science Authors: Ifeanyi Uchegbulam Simon G Danby Roger Lewis Matt J Carr é Raman Maiti Source Type: research

Effect of seasonal change on the biomechanical and physical properties of the human skin
In this study, the effect of one cycle of winter to summer seasonal transition on the mechanical and physical properties of skin was investigated in vivo. Fourteen healthy skin volunteers aged between 22 and 42 years were studied at the volar lower and upper arms. The findings indicate a 22.15% and 34.29% decrease in trans-epidermal water loss (TEWL) and the average epidermal roughness (AER), respectively. Also, improved skin properties were observed such as a 25.48% rise in average epidermal hydration (AEH), 22.59% in skin thickness, 38.64% and 21.92% in melanin and redness, respectively, as well as an 8.25% rise in its f...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 20, 2022 Category: Materials Science Authors: Ifeanyi Uchegbulam Simon G Danby Roger Lewis Matt J Carr é Raman Maiti Source Type: research

Comparative retrieval analysis of contemporary mobile and fixed unicompartmental knee bearing designs
J Mech Behav Biomed Mater. 2022 Jan 8;127:105076. doi: 10.1016/j.jmbbm.2022.105076. Online ahead of print.ABSTRACTThere are two different concepts behind Unicompartmental Knee Replacement (UKR). Mobile bearings, as exemplified by the Oxford UKR, and fixed bearings, as exemplified by the Physica ZUK. These are the two most commonly implanted UKRs in the UK. For the first time, a comparison of the tribological features of 19 explanted Oxford and 19 explanted Physica ZUK UKRs was undertaken. Surface damage on the polyethylene (PE) inserts of the Oxford and Physica ZUK cohorts were assessed using an established semi-quantitati...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 18, 2022 Category: Materials Science Authors: Shannen Chacko Rajan Oana Bretcanu David John Deehan Thomas Jonathan Joyce Source Type: research

Comparative retrieval analysis of contemporary mobile and fixed unicompartmental knee bearing designs
J Mech Behav Biomed Mater. 2022 Jan 8;127:105076. doi: 10.1016/j.jmbbm.2022.105076. Online ahead of print.ABSTRACTThere are two different concepts behind Unicompartmental Knee Replacement (UKR). Mobile bearings, as exemplified by the Oxford UKR, and fixed bearings, as exemplified by the Physica ZUK. These are the two most commonly implanted UKRs in the UK. For the first time, a comparison of the tribological features of 19 explanted Oxford and 19 explanted Physica ZUK UKRs was undertaken. Surface damage on the polyethylene (PE) inserts of the Oxford and Physica ZUK cohorts were assessed using an established semi-quantitati...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 18, 2022 Category: Materials Science Authors: Shannen Chacko Rajan Oana Bretcanu David John Deehan Thomas Jonathan Joyce Source Type: research

Comparative retrieval analysis of contemporary mobile and fixed unicompartmental knee bearing designs
J Mech Behav Biomed Mater. 2022 Jan 8;127:105076. doi: 10.1016/j.jmbbm.2022.105076. Online ahead of print.ABSTRACTThere are two different concepts behind Unicompartmental Knee Replacement (UKR). Mobile bearings, as exemplified by the Oxford UKR, and fixed bearings, as exemplified by the Physica ZUK. These are the two most commonly implanted UKRs in the UK. For the first time, a comparison of the tribological features of 19 explanted Oxford and 19 explanted Physica ZUK UKRs was undertaken. Surface damage on the polyethylene (PE) inserts of the Oxford and Physica ZUK cohorts were assessed using an established semi-quantitati...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 18, 2022 Category: Materials Science Authors: Shannen Chacko Rajan Oana Bretcanu David John Deehan Thomas Jonathan Joyce Source Type: research

A novel hip joint prosthesis with uni-directional articulations for reduced wear
J Mech Behav Biomed Mater. 2022 Jan 3;127:105072. doi: 10.1016/j.jmbbm.2021.105072. Online ahead of print.ABSTRACTA novel polymer-on-metal hip joint prosthesis design that makes use of uni-directional articulations was developed and tested in this work. The new implant was tested using two polymer variants, virgin ultra-high molecular weight polyethylene (UHMWPE), and Vitamin E-infused highly crosslinked polyethylene (VEHXPE). The degrees of freedom of the ball-and-socket are reproduced by three cylindrical orthogonally-aligned articulations. This unconventional design leverages on the molecular orientation hardening mecha...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 16, 2022 Category: Materials Science Authors: Donald Dalli Joseph Buhagiar Pierluigi Mollicone Pierre Schembri Wismayer Source Type: research

Two-versus three-screw osteosynthesis of the mandibular condylar head: A finite element analysis
This study aimed to investigate the biomechanical differences in mandibular condylar head osteosynthesis with two versus three titanium screws using finite element analysis. A finite element model of the mandible with a right type P condylar head fracture fixed with two or three titanium screws was analyzed in ANSYS Mechanical. The geometry of the model assembly was constructed in ANSYS Spaceclaim. Biomechanical load boundary conditions were obtained from a validated musculoskeletal model in AnyBody Modeling System™. The preprocessing of the finite element model and mapping of the obtained boundary conditions was don...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 16, 2022 Category: Materials Science Authors: Daphne Sch önegg G ünter T Müller Michael Blumer Harald Essig Maximilian E H Wagner Source Type: research

A novel hip joint prosthesis with uni-directional articulations for reduced wear
J Mech Behav Biomed Mater. 2022 Jan 3;127:105072. doi: 10.1016/j.jmbbm.2021.105072. Online ahead of print.ABSTRACTA novel polymer-on-metal hip joint prosthesis design that makes use of uni-directional articulations was developed and tested in this work. The new implant was tested using two polymer variants, virgin ultra-high molecular weight polyethylene (UHMWPE), and Vitamin E-infused highly crosslinked polyethylene (VEHXPE). The degrees of freedom of the ball-and-socket are reproduced by three cylindrical orthogonally-aligned articulations. This unconventional design leverages on the molecular orientation hardening mecha...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 16, 2022 Category: Materials Science Authors: Donald Dalli Joseph Buhagiar Pierluigi Mollicone Pierre Schembri Wismayer Source Type: research

Two-versus three-screw osteosynthesis of the mandibular condylar head: A finite element analysis
This study aimed to investigate the biomechanical differences in mandibular condylar head osteosynthesis with two versus three titanium screws using finite element analysis. A finite element model of the mandible with a right type P condylar head fracture fixed with two or three titanium screws was analyzed in ANSYS Mechanical. The geometry of the model assembly was constructed in ANSYS Spaceclaim. Biomechanical load boundary conditions were obtained from a validated musculoskeletal model in AnyBody Modeling System™. The preprocessing of the finite element model and mapping of the obtained boundary conditions was don...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 16, 2022 Category: Materials Science Authors: Daphne Sch önegg G ünter T Müller Michael Blumer Harald Essig Maximilian E H Wagner Source Type: research

Natural cardiac regeneration conserves native biaxial left ventricular biomechanics after myocardial infarction in neonatal rats
J Mech Behav Biomed Mater. 2022 Jan 4;126:105074. doi: 10.1016/j.jmbbm.2022.105074. Online ahead of print.ABSTRACTAfter myocardial infarction (MI), adult mammals exhibit scar formation, adverse left ventricular (LV) remodeling, LV stiffening, and impaired contractility, ultimately resulting in heart failure. Neonatal mammals, however, are capable of natural heart regeneration after MI. We hypothesized that neonatal cardiac regeneration conserves native biaxial LV mechanics after MI. Wistar rat neonates (1 day old, n = 46) and adults (8-10 weeks old, n = 20) underwent sham surgery or permanent left anterior descending coron...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 14, 2022 Category: Materials Science Authors: Hanjay Wang Andrew Wisneski Annabel M Imbrie-Moore Michael J Paulsen Zhongjie Wang Yue Xuan Hector Lopez Hernandez Camille E Hironaka Haley J Lucian Hye Sook Shin Shreya Anilkumar Akshara D Thakore Justin M Farry Anahita Eskandari Kiah M Williams Frederic Source Type: research

Natural cardiac regeneration conserves native biaxial left ventricular biomechanics after myocardial infarction in neonatal rats
J Mech Behav Biomed Mater. 2022 Jan 4;126:105074. doi: 10.1016/j.jmbbm.2022.105074. Online ahead of print.ABSTRACTAfter myocardial infarction (MI), adult mammals exhibit scar formation, adverse left ventricular (LV) remodeling, LV stiffening, and impaired contractility, ultimately resulting in heart failure. Neonatal mammals, however, are capable of natural heart regeneration after MI. We hypothesized that neonatal cardiac regeneration conserves native biaxial LV mechanics after MI. Wistar rat neonates (1 day old, n = 46) and adults (8-10 weeks old, n = 20) underwent sham surgery or permanent left anterior descending coron...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 14, 2022 Category: Materials Science Authors: Hanjay Wang Andrew Wisneski Annabel M Imbrie-Moore Michael J Paulsen Zhongjie Wang Yue Xuan Hector Lopez Hernandez Camille E Hironaka Haley J Lucian Hye Sook Shin Shreya Anilkumar Akshara D Thakore Justin M Farry Anahita Eskandari Kiah M Williams Frederic Source Type: research

In-situ SEM cyclic nanoindentation of pre-sintered and sintered zirconia materials
This study advances the fundamental understanding of nanoindentation mechanics of zirconia materials.PMID:35026563 | DOI:10.1016/j.jmbbm.2021.105068 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 13, 2022 Category: Materials Science Authors: Afifah Z Juri Animesh K Basak Ling Yin Source Type: research

Effects of hybrid inorganic-organic nanofibers on the properties of enamel resin infiltrants - An in vitro study
J Mech Behav Biomed Mater. 2022 Jan 4;126:105067. doi: 10.1016/j.jmbbm.2021.105067. Online ahead of print.ABSTRACTThis in vitro study aimed to evaluate the overall mechanical properties of resin infiltrants doped with bioactive nanofibers and their ability in inhibiting enamel demineralization or achieving remineralization of the adjacent enamel to white spots. A commercial resin infiltrant (ICON, DMG) was doped with hybrid inorganic-organic nanofibers and analyzed for degree of conversion (DC, n = 3) and surface hardness (SH, n = 6). Subsequently, enamel specimens (6 × 4 × 2 mm3) were prepared and submitted to...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 13, 2022 Category: Materials Science Authors: Alyssa Teixeira Obeid Luisa Helena Antunes Garcia Tatiana Rita de Lima Nascimento L úcio Roberto Cançado Castellano Juliana Fraga Soares Bombonatti Heitor Marques Hon ório Rafael Francisco Lia Mondelli Salvatore Sauro Marilia Mattar de Amo êdo Campos Source Type: research

In-situ SEM cyclic nanoindentation of pre-sintered and sintered zirconia materials
This study advances the fundamental understanding of nanoindentation mechanics of zirconia materials.PMID:35026563 | DOI:10.1016/j.jmbbm.2021.105068 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 13, 2022 Category: Materials Science Authors: Afifah Z Juri Animesh K Basak Ling Yin Source Type: research

Effects of hybrid inorganic-organic nanofibers on the properties of enamel resin infiltrants - An in vitro study
J Mech Behav Biomed Mater. 2022 Jan 4;126:105067. doi: 10.1016/j.jmbbm.2021.105067. Online ahead of print.ABSTRACTThis in vitro study aimed to evaluate the overall mechanical properties of resin infiltrants doped with bioactive nanofibers and their ability in inhibiting enamel demineralization or achieving remineralization of the adjacent enamel to white spots. A commercial resin infiltrant (ICON, DMG) was doped with hybrid inorganic-organic nanofibers and analyzed for degree of conversion (DC, n = 3) and surface hardness (SH, n = 6). Subsequently, enamel specimens (6 × 4 × 2 mm3) were prepared and submitted to...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 13, 2022 Category: Materials Science Authors: Alyssa Teixeira Obeid Luisa Helena Antunes Garcia Tatiana Rita de Lima Nascimento L úcio Roberto Cançado Castellano Juliana Fraga Soares Bombonatti Heitor Marques Hon ório Rafael Francisco Lia Mondelli Salvatore Sauro Marilia Mattar de Amo êdo Campos Source Type: research

Development of HAp/GO/Ag coating on 316 LVM implant for medical applications
In this study, antibacterial activity, biocompatibility, and corrosion resistance of 316 LVM implants were improved using the development of HAp/GO/Ag nanocomposite coatings by the dip-coating method. The XRD and FTIR results confirmed the synthesis of HAp/GO/Ag nanocomposites. HAp/Ag nanoparticles (68 nm) bound to epoxy, hydroxyl, and carboxyl functional groups on GO sheets (size of GO sheets varies from 255 to 1480 nm) by electrostatic interaction. FESEM images showed that HAp/GO/Ag coatings had higher density and fewer micro-cracks than pure HAp coatings. In addition, HAp/GO/Ag coatings showed optimized nano-hardness (4...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 10, 2022 Category: Materials Science Authors: Reza Ahmadi Safoura Izanloo Source Type: research

Functional mechanical attributes of natural and synthetic gel-based scaffolds in tissue engineering: strain-stiffening effects on apparent elastic modulus and compressive toughness
J Mech Behav Biomed Mater. 2022 Jan 5;126:105066. doi: 10.1016/j.jmbbm.2021.105066. Online ahead of print.ABSTRACTThe accurate identification and determination of elastic modulus and toughness, as well as other functional mechanical attributes of artificial tissues, are of paramount importance in several fields of tissue science, tissue engineering and technology, since biomechanical and biophysical behavior is strongly linked to biological features of the medical implants and tissue-engineering scaffolds. When soft or ultra-soft materials are investigated, a relevant dispersion of elastic modulus values can be achieved, d...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 10, 2022 Category: Materials Science Authors: Alessandro Schiavi Rugiada Cuccaro Adriano Troia Source Type: research

Development of HAp/GO/Ag coating on 316 LVM implant for medical applications
In this study, antibacterial activity, biocompatibility, and corrosion resistance of 316 LVM implants were improved using the development of HAp/GO/Ag nanocomposite coatings by the dip-coating method. The XRD and FTIR results confirmed the synthesis of HAp/GO/Ag nanocomposites. HAp/Ag nanoparticles (68 nm) bound to epoxy, hydroxyl, and carboxyl functional groups on GO sheets (size of GO sheets varies from 255 to 1480 nm) by electrostatic interaction. FESEM images showed that HAp/GO/Ag coatings had higher density and fewer micro-cracks than pure HAp coatings. In addition, HAp/GO/Ag coatings showed optimized nano-hardness (4...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 10, 2022 Category: Materials Science Authors: Reza Ahmadi Safoura Izanloo Source Type: research

Functional mechanical attributes of natural and synthetic gel-based scaffolds in tissue engineering: strain-stiffening effects on apparent elastic modulus and compressive toughness
J Mech Behav Biomed Mater. 2022 Jan 5;126:105066. doi: 10.1016/j.jmbbm.2021.105066. Online ahead of print.ABSTRACTThe accurate identification and determination of elastic modulus and toughness, as well as other functional mechanical attributes of artificial tissues, are of paramount importance in several fields of tissue science, tissue engineering and technology, since biomechanical and biophysical behavior is strongly linked to biological features of the medical implants and tissue-engineering scaffolds. When soft or ultra-soft materials are investigated, a relevant dispersion of elastic modulus values can be achieved, d...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 10, 2022 Category: Materials Science Authors: Alessandro Schiavi Rugiada Cuccaro Adriano Troia Source Type: research

Development of HAp/GO/Ag coating on 316 LVM implant for medical applications
In this study, antibacterial activity, biocompatibility, and corrosion resistance of 316 LVM implants were improved using the development of HAp/GO/Ag nanocomposite coatings by the dip-coating method. The XRD and FTIR results confirmed the synthesis of HAp/GO/Ag nanocomposites. HAp/Ag nanoparticles (68 nm) bound to epoxy, hydroxyl, and carboxyl functional groups on GO sheets (size of GO sheets varies from 255 to 1480 nm) by electrostatic interaction. FESEM images showed that HAp/GO/Ag coatings had higher density and fewer micro-cracks than pure HAp coatings. In addition, HAp/GO/Ag coatings showed optimized nano-hardness (4...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 10, 2022 Category: Materials Science Authors: Reza Ahmadi Safoura Izanloo Source Type: research

Functional mechanical attributes of natural and synthetic gel-based scaffolds in tissue engineering: strain-stiffening effects on apparent elastic modulus and compressive toughness
J Mech Behav Biomed Mater. 2022 Jan 5;126:105066. doi: 10.1016/j.jmbbm.2021.105066. Online ahead of print.ABSTRACTThe accurate identification and determination of elastic modulus and toughness, as well as other functional mechanical attributes of artificial tissues, are of paramount importance in several fields of tissue science, tissue engineering and technology, since biomechanical and biophysical behavior is strongly linked to biological features of the medical implants and tissue-engineering scaffolds. When soft or ultra-soft materials are investigated, a relevant dispersion of elastic modulus values can be achieved, d...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 10, 2022 Category: Materials Science Authors: Alessandro Schiavi Rugiada Cuccaro Adriano Troia Source Type: research

Using Statistical Shape and Appearance Modelling to characterise the 3D shape and material properties of human lumbar vertebrae: A proof of concept study
J Mech Behav Biomed Mater. 2021 Dec 15;126:105047. doi: 10.1016/j.jmbbm.2021.105047. Online ahead of print.ABSTRACTPatient variation affects the outcomes of a range of spinal interventions, from disc replacement to vertebral fixation and vertebroplasty. Statistical Shape and Appearance Modelling (SSAM) can be used to describe anatomical variation and pathological differences within the population. To better understand how bone density and shape variation affect load transfer with respect to surgical treatments, Finite Element (FE) models can be generated from a SSAM. The aim for this study is to understand whether geometri...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: G A Day A C Jones R K Wilcox Source Type: research

Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach
The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties. It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear. It was further hypothesized that the mechanical properties governing the model depend on the tissue's composition. Frequency sweep tests were conducted on eight porcine meniscal specimens. A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel wi...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Massimiliano De Rosa Giovanni Filippone Thomas M Best Alicia R Jackson Francesco Travascio Source Type: research

Insights into the mechanical interaction between an active cranial implant and the skull subjected to moderate impact loadings
J Mech Behav Biomed Mater. 2021 Dec 15;126:105048. doi: 10.1016/j.jmbbm.2021.105048. Online ahead of print.ABSTRACTIn the context of cochlear implants, which are now widely used, and innovative active devices, the cranial implantation of electronic devices raises new questions about the mechanical interactions between the implant and the skull. The aim of this study was to build a methodology using experimental data and numerical simulations to evaluate the mechanical interactions between the skull and the WIMAGINE® active cranial implant intended for use for tetraplegic patients. A finite element model of the implant ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Alice Siegel Fabien Sauter-Starace S ébastien Laporte Source Type: research

Influence of strut-size and cell-size variations on porous Ti6Al4V structures for load-bearing implants
This study evaluated pore morphology dependence and strut-size on compression, shear deformation, and in vitro response of additively manufactured porous Ti6Al4V structures. Selective laser melting (SLM)-based additive manufacturing (AM) technique was used to process two types of structures with honeycomb cell design-one with constant cell-size of ∼470 μm with mean strut-size varying from 92 to 134 μm, and denoted as strut-size variation (SSV); and the other with a constant strut-size of ∼135 μm with mean cell-size varying from 580 to 740 μm, denoted as cell-size variation (CSV). It was observed that un...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Sushant Ciliveri Amit Bandyopadhyay Source Type: research

A parameter reduced adaptive quasi-linear viscoelastic model for soft biological tissue in uniaxial tension
This study proposes a 'reduced-parameter' AQLV model (2M2N) for the modelling of soft biological tissues at finite strain ranges. Sequentially, the comparison of model parameters of soft tissues is easier and the experimental burden is reduced.PMID:34999491 | DOI:10.1016/j.jmbbm.2021.104999 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Othniel J Aryeetey Martin Frank Andrea Lorenz Sarah-Jane Estermann Andreas G Reisinger Dieter H Pahr Source Type: research

Using Statistical Shape and Appearance Modelling to characterise the 3D shape and material properties of human lumbar vertebrae: A proof of concept study
J Mech Behav Biomed Mater. 2021 Dec 15;126:105047. doi: 10.1016/j.jmbbm.2021.105047. Online ahead of print.ABSTRACTPatient variation affects the outcomes of a range of spinal interventions, from disc replacement to vertebral fixation and vertebroplasty. Statistical Shape and Appearance Modelling (SSAM) can be used to describe anatomical variation and pathological differences within the population. To better understand how bone density and shape variation affect load transfer with respect to surgical treatments, Finite Element (FE) models can be generated from a SSAM. The aim for this study is to understand whether geometri...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: G A Day A C Jones R K Wilcox Source Type: research

Mechanical properties of meniscal circumferential fibers using an inverse finite element analysis approach
The objective of this study was to propose a constitutive model for collagen fibers embedded in the ECM of the meniscus and to characterize the tissue's pertinent mechanical properties. It was hypothesized that a linear fiber reinforced viscoelastic constitutive model is suitable to describe meniscal mechanical behavior in shear. It was further hypothesized that the mechanical properties governing the model depend on the tissue's composition. Frequency sweep tests were conducted on eight porcine meniscal specimens. A first cohort of experimental data resulted from tissue specimens where collagen fibers oriented parallel wi...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Massimiliano De Rosa Giovanni Filippone Thomas M Best Alicia R Jackson Francesco Travascio Source Type: research

Insights into the mechanical interaction between an active cranial implant and the skull subjected to moderate impact loadings
J Mech Behav Biomed Mater. 2021 Dec 15;126:105048. doi: 10.1016/j.jmbbm.2021.105048. Online ahead of print.ABSTRACTIn the context of cochlear implants, which are now widely used, and innovative active devices, the cranial implantation of electronic devices raises new questions about the mechanical interactions between the implant and the skull. The aim of this study was to build a methodology using experimental data and numerical simulations to evaluate the mechanical interactions between the skull and the WIMAGINE® active cranial implant intended for use for tetraplegic patients. A finite element model of the implant ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Alice Siegel Fabien Sauter-Starace S ébastien Laporte Source Type: research

Influence of strut-size and cell-size variations on porous Ti6Al4V structures for load-bearing implants
This study evaluated pore morphology dependence and strut-size on compression, shear deformation, and in vitro response of additively manufactured porous Ti6Al4V structures. Selective laser melting (SLM)-based additive manufacturing (AM) technique was used to process two types of structures with honeycomb cell design-one with constant cell-size of ∼470 μm with mean strut-size varying from 92 to 134 μm, and denoted as strut-size variation (SSV); and the other with a constant strut-size of ∼135 μm with mean cell-size varying from 580 to 740 μm, denoted as cell-size variation (CSV). It was observed that un...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Sushant Ciliveri Amit Bandyopadhyay Source Type: research

A parameter reduced adaptive quasi-linear viscoelastic model for soft biological tissue in uniaxial tension
This study proposes a 'reduced-parameter' AQLV model (2M2N) for the modelling of soft biological tissues at finite strain ranges. Sequentially, the comparison of model parameters of soft tissues is easier and the experimental burden is reduced.PMID:34999491 | DOI:10.1016/j.jmbbm.2021.104999 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 9, 2022 Category: Materials Science Authors: Othniel J Aryeetey Martin Frank Andrea Lorenz Sarah-Jane Estermann Andreas G Reisinger Dieter H Pahr Source Type: research

Evaluation of wear behaviour of various occlusal splint materials and manufacturing processes
J Mech Behav Biomed Mater. 2022 Jan 1;126:105053. doi: 10.1016/j.jmbbm.2021.105053. Online ahead of print.ABSTRACTOBJECTIVES: To investigate the volumetric and vertical loss of occlusal splints manufactured by conventional (heat-cure), subtractive (CAD/CAM) and additive (3D-printing) methods.METHODS: Six occlusal splint materials were investigated (n = 126), using three manufacturing methods: heat-cured, CAD/CAM and 3D-printed built-in three different printing angles (0°,45°and 90°). Block-on-ring wear testing was performed with extracted human molars as the antagonist. All samples were tested with an applied f...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 8, 2022 Category: Materials Science Authors: Anastasiia Grymak John Neil Waddell John M Aarts Sunyoung Ma Joanne Jung Eun Choi Source Type: research

Mechanical properties of brain tissue based on microstructure
J Mech Behav Biomed Mater. 2021 Dec 18;126:104924. doi: 10.1016/j.jmbbm.2021.104924. Online ahead of print.ABSTRACTResearch on the mechanical properties of brain tissue has gradually deepened recently. Two indentation protocols were used here to characterize the mechanical properties of cortical tissues. Further, histological staining was used to explore the correlation between the mechanical properties and microstructure on the basis of the density of cell nuclei and proteoglycan content. No significant difference was observed in transient contact stiffness between the cerebral cortex and cerebellar cortex at the depth in...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 8, 2022 Category: Materials Science Authors: Chi Zhang Changyi Liu Hongwei Zhao Source Type: research

Fabrication of Customized dental guide by stereolithography method and evaluation of dimensional accuracy with artificial neural networks
J Mech Behav Biomed Mater. 2022 Jan 3;126:105071. doi: 10.1016/j.jmbbm.2021.105071. Online ahead of print.ABSTRACTThe present study was investigated the production dental guides by using additive manufacturing stereolithography (SLA) technology, and the dimensional aperture values of the dental guides for dental implant treatment using artificial intelligence technology. The aim of this study is to benefit from artificial neural networks (ANNs) to classify the results obtained from the new production freedom of SLA by changing the existing design concept of dental guides. In the study, the Three Dimensional (3D) anatomical...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 8, 2022 Category: Materials Science Authors: Hasan T ürker Bekir Aksoy Koray Özsoy Source Type: research

Subject specific finite element modelling of periprosthetic femoral fractures in different load cases
In this study, a state-of-the-art subject specific FE modelling technique for bone is utilised to generate and investigate PFF. A bilinear constitutive law is applied to bone tissue in subject specific FE models of five human femurs which are virtually implanted with a straight hip stem to numerically analyse PFF. The material parameters of the models are expressed as a function of bone ash density and mapped node wise to the FE mesh. In this way the subject specific, heterogeneous structure of bone is mimicked. For material mapping of the parameters, computed tomography (CT) images of the original fresh-frozen femurs are ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 7, 2022 Category: Materials Science Authors: N S Hennicke M Saemann D Kluess R Bader M Sander Source Type: research

In vitro biocompatiability and mechanical properties of bone adhesive tape composite based on poly(butyl fumarate)/poly(propylene fumarate)-diacrylate networks
J Mech Behav Biomed Mater. 2021 Dec 28;126:105049. doi: 10.1016/j.jmbbm.2021.105049. Online ahead of print.ABSTRACTPolyfumarate has been considered as injectable and biodegradable bone cement. However, its mechanical and degradation properties are particularly important. Therefore, the current study aimed to develop the properties by compositing poly (butyl fumarate)-based networks with hydroxyapatite nano-powders. In this regard, the poly (butyl fumarate) (PBF) matrix composite was compared with different components by evaluating their composition, mechanical properties, hydrophilicity, and biodegradability. Furthermore, ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 6, 2022 Category: Materials Science Authors: Liang Wang Ge-Qing Zhang Xin-Hai He Yan-Dong Cui Najeeb Ur Rehman Lashari Da-Gang Guo Jing Zheng Source Type: research

Cardiac mesh morphing method for finite element modeling of heart failure with preserved ejection fraction
In this study, we propose a novel and easily adaptable cardiac reconstruction algorithm by morphing an existing discretized mesh of an advanced finite element (FE) model, to match anatomies acquired from porcine cardiac magnetic resonance imaging (cMRI) scans. The morphing algorithm involves iterative FE simulations with visco-hyperelastic material properties. The living heart porcine model (LHPM) was chosen as the input baseline FE mesh, in order to preserve detailed anatomical features that cannot be captured in routine scans such as myofiber orientations and conduction pathways. The algorithm was demonstrated for the re...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 3, 2022 Category: Materials Science Authors: Jonathan Weissmann Christopher J Charles A Mark Richards Choon Hwai Yap Gil Marom Source Type: research

Design and surface characterization of micropatterned silica coatings for zirconia dental implants
J Mech Behav Biomed Mater. 2021 Dec 24;126:105060. doi: 10.1016/j.jmbbm.2021.105060. Online ahead of print.ABSTRACTThe use of zirconia as an alternative biomaterial for titanium implants has been increasing due to its biocompatibility, favorable aesthetic features, less potential for early plaque accumulation and mechanical properties. Despite the developed efforts, strategies to promote an effective osseointegration are still enough. In this sense and combining the silica properties to improve bone formation with the micropatterning guidance characteristics, silica coatings with micropatterns were designed and evaluated r...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 2, 2022 Category: Materials Science Authors: Andr é Moreira Sara Madeira Mihaela Buciumeanu Joana Fialho Angela Carvalho Filipe Silva Fernando J Monteiro Jo ão Caramês Source Type: research

Effects of scattering on ultrasound wave transmission through bioinspired scaffolds
In this study we investigate how ultrasound wave transmission differs between scaffolds with uniform pore shapes (triangle, square, rectangle, hexagon) and a bioinspired scaffold with higher structural integrity that is inspired from the atomic structure of hydroxyapatite which is a primary component of bone. We use finite element method and ultrasound experiments on 3D-printed scaffolds composed of Acrylonitrile butadiene styrene (ABS) with constant porosity to predict the effect of pore shape and wave signal frequency in the range of 1-20 MHz on acoustic wave scattering and transmission. We find that the pore shape of th...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 2, 2022 Category: Materials Science Authors: Marco Fielder Arun K Nair Source Type: research

Design and surface characterization of micropatterned silica coatings for zirconia dental implants
J Mech Behav Biomed Mater. 2021 Dec 24;126:105060. doi: 10.1016/j.jmbbm.2021.105060. Online ahead of print.ABSTRACTThe use of zirconia as an alternative biomaterial for titanium implants has been increasing due to its biocompatibility, favorable aesthetic features, less potential for early plaque accumulation and mechanical properties. Despite the developed efforts, strategies to promote an effective osseointegration are still enough. In this sense and combining the silica properties to improve bone formation with the micropatterning guidance characteristics, silica coatings with micropatterns were designed and evaluated r...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 2, 2022 Category: Materials Science Authors: Andr é Moreira Sara Madeira Mihaela Buciumeanu Joana Fialho Angela Carvalho Filipe Silva Fernando J Monteiro Jo ão Caramês Source Type: research

Effects of scattering on ultrasound wave transmission through bioinspired scaffolds
In this study we investigate how ultrasound wave transmission differs between scaffolds with uniform pore shapes (triangle, square, rectangle, hexagon) and a bioinspired scaffold with higher structural integrity that is inspired from the atomic structure of hydroxyapatite which is a primary component of bone. We use finite element method and ultrasound experiments on 3D-printed scaffolds composed of Acrylonitrile butadiene styrene (ABS) with constant porosity to predict the effect of pore shape and wave signal frequency in the range of 1-20 MHz on acoustic wave scattering and transmission. We find that the pore shape of th...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 2, 2022 Category: Materials Science Authors: Marco Fielder Arun K Nair Source Type: research

Mechanical characterization of TiO < sub > 2 < /sub > nanowires flexible scaffold by nano-indentation/scratch
J Mech Behav Biomed Mater. 2021 Dec 28;126:105069. doi: 10.1016/j.jmbbm.2021.105069. Online ahead of print.ABSTRACTMechanical properties of nanowires (NWs) flexible scaffold biomaterials with open pores and channels are important factors to cell reorganize in growth for tissue regeneration engineering. However, accurate test the mechanical properties of the NWs scaffold is still a challenge because of their flexible property and porous structure. Herein, we measured the mechanical characterizes of TiO2 nanowires (TiO2NWs) flexible scaffold by multi-loads, multi-displacements mixed verification method in nano-indentation/sc...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 1, 2022 Category: Materials Science Authors: Licheng Hua Conghu Hu Jin Li Bin Huang Jianke Du Source Type: research

Mechanical and fatigue behaviour of artificial ligaments (ALs)
J Mech Behav Biomed Mater. 2021 Dec 27;126:105063. doi: 10.1016/j.jmbbm.2021.105063. Online ahead of print.ABSTRACTA flexible biologic band, ACL is the most injured and ruptured ligament in the knees of humans and animals. This research aims to produce synthetic anterior cruciate ligaments (ACLs) and compare these ligaments' mechanical and fatigue life properties with the natural ACL and commercial synthetic grafts. Artificial ligaments were designed as a core-sheath type structure. The core consisted of straight, parallel yarns and the sheath was a tubular fabric produced by weaving or braiding techniques from polyester o...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 1, 2022 Category: Materials Science Authors: C Aka G Basal Source Type: research