High pressure torsion induced lowering of Young's modulus in high strength TNZT alloy for bio-implant applications.
This study may be useful for developing excellent removable implant materials. PMID: 32469711 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Maity T, Balcı Ö, Gammer C, Ivanov E, Eckert J, Prashanth KG Tags: J Mech Behav Biomed Mater Source Type: research

Two-body wear test of enamel against laboratory polished and clinically adjusted zirconia.
CONCLUSION: Within the constraints of the test method in this experiment, zirconia irrespective of surface preparation, was found to cause less vertical and volumetric enamel wear compared to control enamel. No statistically significant difference was seen between LP zirconia and LP + CA zirconia. PMID: 32469712 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Mehzabeen KR, Boughton P, Kan WH, Ruys AJ, Guazzato M Tags: J Mech Behav Biomed Mater Source Type: research

Laser powder bed fusion of titanium-tantalum alloys: Compositions and designs for biomedical applications.
This study further shows that porous TiTa scaffolds fabricated using L-PBF are biocompatible with comparable biological results and manufacturability as Ti6Al4V and commercially pure titanium, based on the results obtained from cell culture with human osteosarcoma cell line SAOS-2. PMID: 32469713 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Huang S, Sing SL, de Looze G, Wilson R, Yeong WY Tags: J Mech Behav Biomed Mater Source Type: research

3D printed biodegradable functional temperature-stimuli shape memory polymer for customized scaffoldings.
Abstract Shape memory polymers (SMPs) and their composites have become the prominent choice of the various industries owing to the unique inherent characteristics which can be stimulated through the exposure of external stimuli. The use of SMPs in the three-dimensional (3D) technologies has produced enormous advantages. However, the potential of SMPs in 3D printing has limitedly explored. In the present study, an investigation was performed to study the shape memory effect (SME) of the fused filament fabricated (FFF) chitosan (CS) reinforced poly-lactic-acid (PLA) based porous scaffolds. Firstly, the composite fil...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Pandey A, Singh G, Singh S, Jha K, Prakash C Tags: J Mech Behav Biomed Mater Source Type: research

Enhanced healing of rat calvarial defects with 3D printed calcium-deficient hydroxyapatite/collagen/bone morphogenetic protein 2 scaffolds.
Abstract In this paper, we mainly to evaluate the newly formed bone using the Calcium deficient hydroxyapatite (CDHA)/collagen-based bio-ceramic scaffold as Bone Morphogenetic Protein-2 (BMP-2) carrier in rat calvarial critical-sized bone defect. In the real-time PCR analysis, the CDHA/collagen scaffold loaded rhBMP-2 group showed significantly enhanced results of bone-related gene expression (p 
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Han SH, Lee J, Lee KM, Jin YZ, Yun HS, Kim G, Lee JH Tags: J Mech Behav Biomed Mater Source Type: research

Improvements of material removal in cortical bone via impact cutting method.
Abstract Bone cutting with high efficiency as well as low levels of forces and damage has a great significance for orthopaedic surgeries. Due to the brittleness and anisotropy of cortical bone, a conventional cutting process can cause irregular crack propagation and fractured bone chip, affecting the tissue removal process and postoperative recovery. In this paper, a high-frequency impact cutting method is investigated, and its effect on fracture propagation, chip formation and cutting forces is studied for orthogonal cutting. Experimental results show that cracks are deflected by cement lines in conventional cutt...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Bai W, Shu L, Sun R, Xu J, Silberschmidt VV, Sugita N Tags: J Mech Behav Biomed Mater Source Type: research

A biomimetic urethral model to evaluate urinary catheter lubricity and epithelial micro-trauma.
Abstract The standard method of evaluating the lubricity of intermittent urinary catheters with coefficient of friction (CoF) testing is not physiologically relevant, while there is also a dearth of published research on catheter-associated urethral micro-trauma. We developed a novel human urethral epithelial cell-seeded model of the urethra to replace the rubber counter-surface used in standard CoF testing. This cell-seeded model, in conjunction with a novel testing device, allows an investigation of catheter-associated epithelial micro-trauma in vitro for the first time. The CoF of four brands of commercially-av...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Humphreys O, Pickering M, O'Cearbhaill ED, Flanagan TC Tags: J Mech Behav Biomed Mater Source Type: research

Surface and mechanical properties of a nanostructured citrate hydroxyapatite coating on pure titanium.
In this study, new citrate-HAP (cHAP) coatings were produced by a simple hydrothermal method on pure titanium (Ti) surface, without requiring any additional pretreatment on this metal surface. The formed cHAP coatings consisting of nanorod-like hydroxyapatite particles, conferred nanoroughness and wettability able to endow improved biological responses. Indeed, the presence of citrate species in the precipitate medium seems to be responsible for controlling the morphology of the new coatings. The presence of citrate groups on the surface of cHAP coatings, identified by chemical composition analysis, due to their implicatio...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Arrés M, Salama M, Rechena D, Paradiso P, Reis L, Alves MM, Botelho do Rego AM, Carmezim MJ, Vaz MF, Deus AM, Santos C Tags: J Mech Behav Biomed Mater Source Type: research

Estimation of the hyperelastic parameters of fresh human oropharyngeal soft tissues using indentation testing.
This study has provided estimates of the hyperelastic parameters of all upper airway soft tissues using fresh human tissue specimens for the first time. PMID: 32469719 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Haddad SMH, Dhaliwal SS, Rotenberg BW, Ladak HM, Samani A Tags: J Mech Behav Biomed Mater Source Type: research

Extrusion of the biodegradable ZnMg0.8Ca0.2 alloy - The influence of extrusion parameters on microstructure and mechanical characteristics.
In this study, we focused on the influence of extrusion parameters, such as temperature and extrusion ratio, on microstructural and mechanical characteristics of a ZnMg0.8Ca0.2 (wt.%) alloy. The extrusion led to a significant grain refinement and the formation of a crystallographic texture. Extrusion temperature played a more significant role in the mean grain size compared to the extrusion ratio (ER). At lower extrusion temperatures, the texture was less intensive and the subsequent mechanical anisotropy was weaker. Constants for the prediction of the grain size based on the Zener-Hollomon parameter were obtained. Predict...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Čapek J, Kubásek J, Pinc J, Drahokoupil J, Čavojský M, Vojtěch D Tags: J Mech Behav Biomed Mater Source Type: research

Deformation behavior of normal human enamel: A study by nanoindentation.
We examined the distribution of hardness and modulus across the lingual-buccal enamel cross-section by nanoindentation. At the occlusal surface, the hardness and modulus of enamel were found to be 5.00 ± 0.22 GPa and 97.12 ± 2.95 GPa, respectively. At the area close to the enamel-dentine-junction (EDJ), the hardness and modulus were 3.72 ± 0.35 GPa and 76.83 ± 5.71 GPa, respectively. At the middle region in between the EDJ and the outer enamel layer, the hardness and modulus were found to be 4.23 ± 0.18 GPa and 87....
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Shen L, Barbosa de Sousa F, Tay N, Lang TS, Kaixin VL, Han J, Kilpatrick-Liverman L, Wang W, Lavender S, Pilch S, Gan HY Tags: J Mech Behav Biomed Mater Source Type: research

The significant impact of mechanically-induced phase transformation on cellular functionality of biomedical austenitic stainless steel.
Abstract The implant surface and tissue experience strain when micro-motion occurs at the bone-implant interface under physiological loading. Moreover, strain is also introduced on the surface during mechanical processing of biomedical devices. Both these situations can induce phase transformation depending on the degree of stability of the microstructural constituents. In this regard, we elucidate here the interplay between mechanically-induced phase transformation (strain-induced martensite) in austenitic stainless steel on osteoblast functions. Strain-induced martensite significantly impacted cellular functions...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Challa VSA, Nune KC, Gong N, Misra RDK Tags: J Mech Behav Biomed Mater Source Type: research

3D metal printing in dentistry: An in vitro biomechanical comparative study of two additive manufacturing technologies for full-arch implant-supported prostheses.
esquita MF Abstract The use of 3D technologies is progressing in the dental field. However, little is known about the biomechanical behavior of the additive manufacturing of full-arch fixed dental prostheses (FAFDPs) for the establishment of clinical protocols. We investigated the influence of three CAD/CAM technologies: milling (control), Selective Laser Melting (SLM) and Electron Beam Melting (EBM) for FAFDP manufacturing. Also, the effects of ceramic veneer and spark erosion on marginal misfits of FAFDPs, the stability of prosthetic screws, strain and stress on the implant-supported system, as well as the effec...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Barbin T, Velôso DV, Del Rio Silva L, Borges GA, Presotto AGC, Barão VAR, Mesquita MF Tags: J Mech Behav Biomed Mater Source Type: research

Mechanical behaviour of additively manufactured bioactive glass/high density polyethylene composites.
In this study, BAG is added to a polymer to induce bioactivity and to realize fused filament fabrication (FFF) based printing of polymer composites for potential orthopaedic implant applications. BAG (5, 10, and 20 wt%) is melt compounded with high density polyethylene (HDPE) and subsequently extruded into feedstock filament for FFF-printing. Tensile tests on developed filaments reveal that they are stiff enough to resist forces exerted during the printing process. Micrography of printed HDPE/BAG reveals perfect diffusion of raster interface indicating proper selection of printing parameters. Micrography of freeze fra...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Jeyachandran P, Bontha S, Bodhak S, Balla VK, Kundu B, Doddamani M Tags: J Mech Behav Biomed Mater Source Type: research

Effect of indenter material on reliability of all-ceramic crowns.
Abstract OBJECTIVES: Controversy exists about whether the elastic modulus (E) mismatch between the loading indenter and ceramic materials influences fatigue testing results. The research hypotheses were that for porcelain veneered Y-TZP crowns 1) A low modulus Steatite indenter (SB) leads to higher fatigue reliability compared to a high modulus tungsten carbide indenter (WC); 2) Different surface damage patterns are expected between low and high modulus indenters after sliding contact fatigue testing. All ceramic crowns will exhibit similar step-stress accelerated life testing (SSALT) contact fatigue reliability (...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Lorenzoni FC, Bonfante EA, Valverde GB, Coelho PG, Bonfante G, Thompson VP, Silva NRFA Tags: J Mech Behav Biomed Mater Source Type: research

Mechanical properties of native and acellular temporal muscle fascia for surgical reconstruction and computational modelling purposes.
This study provides tensile data of 52 TMFs at an age range of 18 to 94 years. It further investigates, if acellular fascia scaffolds differ from native counterparts in their biomechanical behaviour. Native TMF has a median elastic modulus of 26.2 MPa (acellular: 24.5 MPa), an ultimate tensile strength of 2.9 MPa (acellular: 2.1 MPa), a maximum force of 12.6 N (acellular: 9.9 N) and a strain at failure of 14.1% (acellular: 14.8%). No significant difference was found regarding the properties of native and acellular samples. Elastic modulus and the ultimate tensile strength increased with age but onl...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Zwirner J, Ondruschka B, Scholze M, Schulze-Tanzil G, Hammer N Tags: J Mech Behav Biomed Mater Source Type: research

Physicochemical properties of dimethacrylate resin composites with comonomer of Hexa/Tri-ethylene glycol bis(carbamate-isoproply- α-methylstyrene).
Physicochemical properties of dimethacrylate resin composites with comonomer of Hexa/Tri-ethylene glycol bis(carbamate-isoproply-α-methylstyrene). J Mech Behav Biomed Mater. 2020 Aug;108:103832 Authors: He J, Garoushi S, Säilynoja E, Vallittu PK, Lassila L Abstract New photocurable "Phene" like monomers Hexaethylene glycol bis(carbamate-isoproply-α-methylstyrene) (HE-Phene) and Triethylene glycol bis(carbamate-isoproply-α-methylstyrene) (TE-Phene) were synthesized and incorporated into Bis-GMA/TEGDMA with the aim of reducing polymerization shrinkage without detriment t...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: He J, Garoushi S, Säilynoja E, Vallittu PK, Lassila L Tags: J Mech Behav Biomed Mater Source Type: research

Collagen peptide simulated bending after applied axial deformation.
In this study we used steered molecular dynamics to first model a collagen peptide under axial tension and then apply a perpendicular bending force. Axial tension causes molecular elongation and increased the subsequent perpendicular bending stiffness, but surprisingly did not increase the predicted collagen triple helix microunfolding threshold. We believe these results elucidate a key potential mechanism by which microscale mechanical loads translate from cellular and micro scales down to the nano and atomistic. Further, these data predict that cryptic force-induced collagen triple helix unwinding is axial-deformation in...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 31, 2020 Category: Materials Science Authors: Bourne JW, Shi L, Torzilli PA Tags: J Mech Behav Biomed Mater Source Type: research

Effect of cooling rate on hardness and microstructure of Pd-Ag-In-Sn-Ga alloy during porcelain firing simulation.
This study examined the effect of the cooling rate on the hardness and its effect on the microstructure during porcelain firing simulation of a Pd-Ag-In-Sn-Ga metal-ceramic alloy. In practice, after each firing step for porcelain bonding, the prosthesis is cooled to room temperature before proceeding to the next firing step. The cooling step is known to allow the hardness of the metal substructure to increase. The aim of the study was to determine whether controlling the cooling rate after each porcelain-firing step increases the hardness of the Pd-Ag-based metal-ceramic alloy. The results showed that the hardness of speci...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Shin HJ, Kwon YH, Seol HJ Tags: J Mech Behav Biomed Mater Source Type: research

High load frequency at 20Hz: Its effects on the fatigue behavior of a leucite-reinforced glass-ceramic.
Abstract Considering the long time spent in low frequency cyclic fatigue tests, this study aimed to evaluate the influence of loading frequency (2 Hz and 20 Hz) on the flexural fatigue strength (FFS) and on the time and number of cycles to failure of a leucite-reinforced glass-ceramic. Disc-shaped specimens were produced using leucite-reinforced glass-ceramic CAD/CAM blocks (IPS Empress CAD), according to ISO 6872/2015. Two fatigue tests were performed. The FFS (n = 17) was determined by staircase approach at a lifetime of 500,000 cycles, for 2 Hz (control - chewing frequency estimative) a...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Fraga S, Rodrigues CDS, Zucuni CP, Pereira GKR, Barbosa MN, Valandro LF, May LG Tags: J Mech Behav Biomed Mater Source Type: research

Biaxial test and hyperelastic material models of silicone elastomer fabricated by extrusion-based additive manufacturing for wearable biomedical devices.
This study investigates the experimental setup and methods to measure and characterize mechanical properties of AM solid and porous silicone elastomer sheets on equi-biaxial stretch (with the stretch ratio up to 2). Four hyperelastic material models were applied to characterize the AM silicone sheet and evaluated through the finite element analysis (FEA) to quantify the fit to biaxial tensile test results. The Yeoh model with C10 = 80.7 kPa, C20 = -2.11 kPa, and C30 = 0.22 kPa has the best match to the experimentally measured stress-strain curve as well as the force and strain i...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Putra KB, Tian X, Plott J, Shih A Tags: J Mech Behav Biomed Mater Source Type: research

Multiscale structural insights of load bearing bamboo: A computational modeling approach.
Abstract Bamboo has been widely utilized as a load bearing material in building construction since ancient times by taking advantage of its excellent mechanical performances under loading as well as its low density and rapid growth. Applications of bamboo to engineering, architecture, and infrastructure require an in-depth understanding of the relationship between its morphology and mechanics, including how this regularly spaced segmental structure adapts to taking the applied loads. However, previous research on buckling behavior of structural bamboo considered it as a homogenous tube without multiscale structura...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Cui J, Qin Z, Masic A, Buehler MJ Tags: J Mech Behav Biomed Mater Source Type: research

Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish.
Abstract Despite sharing oncogenetic mutations, only a small number of cells within a given tissue will undergo malignant transformation. Biochemical and physical factors responsible for this cancer-initiation process are not well understood. Here we study biophysical differences of pre-melanoma and melanoma cells in a BRAFV600E/P53 zebrafish model. The AFM indentation technique was used to study the cancer-initiating cells while the surrounding melanocytes were the control. We observed a statistically significant decrease in the modulus of elasticity (the effective Young's modulus) of cancer-initiating cells comp...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Makarova N, Kalaparthi V, Wang A, Williams C, Dokukin ME, Kaufman CK, Zon L, Sokolov I Tags: J Mech Behav Biomed Mater Source Type: research

Mechanical properties and failure deformation mechanisms of yak horn under quasi-static compression and dynamic impact.
Abstract In the natural environment, the horns of yak possess remarkable structural mechanical properties to protect the head from injury. In this paper, quasi-static compression and dynamic impact tests were conducted on yak horn in different regions under axial and lateral conditions to evaluate mechanical properties such as elastic modulus, ultimate strength and energy absorption. Meanwhile, the failure deformation mechanism under both low and high strain rates is explored. Moreover, experimental analysis of the correlation among mechanical properties, sampling position, strain rate and loading direction was co...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Liu S, Xu S, Song J, Zhou J, Xu L, Li X, Zou M Tags: J Mech Behav Biomed Mater Source Type: research

Analysis of multiple shear wave modes in a nonlinear soft solid: Experiments and finite element simulations with a tilted acoustic radiation force.
Abstract Tissue nonlinearity is conventionally measured in shear wave elastography by studying the change in wave speed caused by the tissue deformation, generally known as the acoustoelastic effect. However, these measurements have mainly focused on the excitation and detection of one specific shear mode, while it is theoretically known that the analysis of multiple wave modes offers more information about tissue material properties that can potentially be used to refine disease diagnosis. This work demonstrated proof of concept using experiments and finite element simulations in a uniaxially stretched phantom by...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Caenen A, Knight AE, Rouze NC, Bottenus NB, Segers P, Nightingale KR Tags: J Mech Behav Biomed Mater Source Type: research

Elemental analysis of commercial zirconia dental implants - Is "metal-free" devoid of metals?
Elemental analysis of commercial zirconia dental implants - Is "metal-free" devoid of metals? J Mech Behav Biomed Mater. 2020 Jul;107:103759 Authors: Gross C, Bergfeldt T, Fretwurst T, Rothweiler R, Nelson K, Stricker A Abstract OBJECTIVES: The interest in ceramic dental implants made of yttria-stabilized tetragonal zirconia polycrystals (Y-TZP) or alumina toughened zirconia (ATZ) has increased in recent years. However, in the light of aging, corrosion, and potential impurities of zirconia ceramics, the material composition of these implants and the associated term "metal-free" is ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Gross C, Bergfeldt T, Fretwurst T, Rothweiler R, Nelson K, Stricker A Tags: J Mech Behav Biomed Mater Source Type: research

In silico analysis of Superelastic Nitinol staples for trans-sternal closure.
CONCLUSION: Computational results prove that superelastic Nitinol staples are promising candidates as alternatives to routinely performed techniques for sternal closure. PMID: 32364952 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 5, 2020 Category: Materials Science Authors: Subasi O, Torabnia S, Lazoglu I Tags: J Mech Behav Biomed Mater Source Type: research

Maturity-dependent cartilage cell plasticity and sensitivity to external perturbation.
CONCLUSION: This study demonstrates differential, nonlinear expression of chondroprogenitor markers and matrix synthesis genes as a function of cartilage maturity, as well as loss of biological plasticity in aged tissue. These findings have likely implications for age-related loss of regeneration and osteoarthritis progression. PMID: 32321631 [PubMed - in process] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 25, 2020 Category: Materials Science Authors: Walsh SK, Schneider SE, Amundson LA, Neu CP, Henak CR Tags: J Mech Behav Biomed Mater Source Type: research

External and internal responses of cervical disc arthroplasty and anterior cervical discectomy and fusion: A finite element modeling study.
Abstract Surgical treatment for spinal disorders, such as cervical disc herniation and spondylosis, includes the removal of the intervertebral disc and replacement of biological or artificial materials. In the former case, bone graft is used to fill the space, and this conventional procedure is termed anterior cervical discectomy and fusion (ACDF). The latter surgery is termed as artificial disc replacement ADR) or cervical disc arthroplasty (CDA). Surgeries are most commonly performed at one or two levels. The present study was designed to determine the external (range of motion, ROM) and internal (anterior and p...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 25, 2020 Category: Materials Science Authors: Purushothaman Y, Yoganandan N, Jebaseelan D, Choi H, Baisden J Tags: J Mech Behav Biomed Mater Source Type: research

Extrafibrillar matrix yield stress and failure envelopes for mineralised collagen fibril arrays.
This study identified yield properties of extrafibrillar matrix using an aligned mineralised tissue. The ability to obtain yield stress data and unloading stiffness from micropillar compression tests of MTLT at the level of the mineralised collagen fibril array and downscaling these into the EM mitigates against possible errors associated with macroscopic stiffness predictions and proved to be an invaluable advantage compared to similar modelling approaches. Results may help to improve computational models that may then be used in pre-clinical testing or development of personalised treatment strategies. PMID: 32279843...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Speed A, Groetsch A, Schwiedrzik JJ, Wolfram U Tags: J Mech Behav Biomed Mater Source Type: research

Inverse correlations between wear and mechanical properties in biphasic dental materials with ceramic constituents.
The objective of this study is to elucidate the interdependence of competing mechanical degradation processes in biphasic dental materials with ceramic constituents in the region of high-pressure occlusal loading. It is hypothesized that wear resistance in this region correlates inversely with basic material parameters (modulus, hardness, toughness, strength) evaluated from 'standardized' test specimens. Ball-on-flat wear tests in simulation of oral function are used to quantify susceptibility to protracted sliding contact damage. Wear rates for this class of dental material tend to increase with quasistatic parameter valu...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Borrero-Lopez O, Guiberteau F, Zhang Y, Lawn BR Tags: J Mech Behav Biomed Mater Source Type: research

Human lumbar spinal column injury criteria from vertical loading at the base: Applications to military environments.
The objective of this study was to determine force-based lumbar spine injury criteria due to vertical impact using Post Mortem Human Surrogate (PMHS) experiments. Mounted personnel in military vehicles sustain loads from the pelvis in combat events such as underbody blast loadings. Forty-three post mortem human subject thoracolumbar spinal columns were obtained, screened for pre-existing trauma, bone mineral densities (BMDs) were determined, pre-test radiological images were taken, fixed at the ends in polymethylmethacrylate, load cells were attached to the ends of the fixation, positioned on custom vertical accelerator de...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Yoganandan N, Moore J, DeVogel N, Pintar F, Banerjee A, Baisden J, Zhang JY, Loftis K, Barnes D Tags: J Mech Behav Biomed Mater Source Type: research

Structure, mechanical properties, and modeling of cyclically compressed pulmonary emboli.
We describe the hysteretic response characteristic of foams, using a model of phase transitions in which the compressed foam is segregated into coexisting rarefied and densified phases whose fractions change during compression. Our model takes account of the rupture of RBCs in the compressed emboli and stresses due to fluid flow through their small pores. Our results can help in classifying emboli as rich in fibrin or rich in red blood cells, and can help in understanding what responses to expect when stresses are applied to thrombi in vivo. PMID: 32279846 [PubMed - in process] (Source: Journal of the Mechanical Behav...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Chernysh IN, Spiewak R, Cambor CL, Purohit PK, Weisel JW Tags: J Mech Behav Biomed Mater Source Type: research

Design of a patient-specific mandible reconstruction implant with dental prosthesis for metal 3D printing using integrated weighted topology optimization and finite element analysis.
This study developed a design strategy with weighted topology optimization and fabrication for producing patient-specific implants using metal 3D printing. The obtained reconstruction implant can provide good biomechanical performance and recovery of appearance for oral rehabilitation. PMID: 32279847 [PubMed - in process] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Li CH, Wu CH, Lin CL Tags: J Mech Behav Biomed Mater Source Type: research

Shear wave speeds track axial stress in porcine collateral ligaments.
Abstract Ligament tension is an important factor that can affect the success of total knee arthroplasty (TKA) procedures. However, surgeons currently lack objective approaches for assessing tension in a particular ligament intraoperatively. The purpose of this study was to investigate the use of noninvasive shear wave tensiometry to characterize stress in medial and lateral collateral ligaments (MCLs and LCLs) ex vivo and evaluate the capacity of shear wave speed to predict axial load. Nine porcine MCL and LCL specimens were subjected to cyclic axial loading while shear wave speeds were measured using laser vibrom...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Blank JL, Thelen DG, Roth JD Tags: J Mech Behav Biomed Mater Source Type: research

Topology optimization of 3D-printed structurally porous cage for acetabular reinforcement in total hip arthroplasty.
Abstract Aseptic loosening and mechanical failure of acetabular reinforcement components are among the main causes of their reduced service life. Current acetabular implants typically feature a structural solid layer that provides load bearing capacity, coated with a foam of uniform porosity to reduce stress shielding and implant loosening. This paper presents an alternative concept for a 3D printed cage that consists of a multifunctional fully porous layer with graded attributes that integrate both structural function and bone in-growth properties. The design comprises a hemispherical cup affixed to a superior fl...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Moussa A, Rahman S, Xu M, Tanzer M, Pasini D Tags: J Mech Behav Biomed Mater Source Type: research

Mechanical performance, corrosion and tribological evaluation of a Co-Cr-Mo alloy processed by MIM for biomedical applications.
In this study, the processing parameters mechanical performance, corrosion and tribological evaluation of a low carbon content Co-Cr-Mo alloy are discussed. The production of parts using the Metal Injection Moulding (MIM) process is optimized, specifically concerning the rheological analysis of the prepared feedstocks, the optimum choice of the powder loading and the design of the debinding and sintering cycles. The mechanical properties as regards hardness, tensile strength and bending strength, as well as fatigue tests and wear characterization, are discussed for the full densified specimens obtained. Additionally, corro...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Herranz G, Berges C, Naranjo JA, García C, Garrido I Tags: J Mech Behav Biomed Mater Source Type: research

Fabrication of ZrO2-Bearing lithium-silicate glass-ceramics by pressureless sintering and spark plasma sintering.
Abstract OBJECTIVE: the present study evaluated the effect of the Spark Plasma Sintering (SPS) and Pressureless Sintering (PLS) methods on the physical and mechanical properties of ZrO2-bearing Lithium Silicate (ZLS) glass-ceramics. METHOD: SPS and PLS methods were used for fabricating of the zirconia-bearing Lithium Silicate glass-ceramics. Several sintering temperatures were applied in order to achieving the best mechanical and physical properties in both methods. For this purpose, the particle size measurement of the glass powder was performed. Field Emission Scanning Electron Microscope (FESEM) was carrie...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Ghayebloo M, Alizadeh P, Melo RM Tags: J Mech Behav Biomed Mater Source Type: research

Shear bond strength of composite cement to alumina-coated versus tribochemical silica-treated zirconia.
Abstract OBJECTIVES: To compare the shear bond strength of composite-resin cement to nano-structured alumina-coated versus to tribochemical silica-treated zirconia, and to analyze the residual stresses on both of nano-structured alumina-coated versus tribochemical silica-treated zirconia specimens. METHODS: One hundred and eighty zirconia disks (10 mm and 5 mm in diameter, 5 mm thickness) were divided into two groups: nano-structured alumina coating (H.C.Starck, AlN) and tribochemical silica treatment (CoJet) followed by RelyX Ceramic Primer (COJ). For each group, two different sizes of identic...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Thammajaruk P, Blatz MB, Buranadham S, Guazzato M, Wang Y Tags: J Mech Behav Biomed Mater Source Type: research

Extraction force and its determinants for minimally invasive vertical tooth extraction.
CONCLUSIONS: Extraction forces using the Benex® vertical extraction system vary widely and can be less than 50N or exceed 600N. On average, higher extraction forces are required to extract teeth with longer and thicker roots, as well as for teeth that are in functional occlusion. PMID: 32279853 [PubMed - in process] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Dietrich T, Schmid I, Locher M, Addison O Tags: J Mech Behav Biomed Mater Source Type: research

Wear analysis and topographical properties of monolithic zirconia and CoCr against human enamel after polishing and glazing procedures.
n M Abstract PURPOSE: Intraoral adjustments of monolithic zirconia (MZ) necessitate intraoral grinding and polishing procedures, causing surface topography changes. The effect of various polishing and glazing procedures on surface roughness, topographical and phase changes of CoCr compared to zirconia, and assessment of the wear of the opposing dentition has been evaluated in this study. MATERIALS AND METHODS: One group of square Cobaltchromium (CoCr) and four groups of sintered and polished zirconia specimens (12 × 12 × 1mm) were fabricated (N = 5, n = 8) u...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Fontolliet A, Al-Haj Husain N, Özcan M Tags: J Mech Behav Biomed Mater Source Type: research

A multi-throughput mechanical loading system for mouse intervertebral disc.
In this study, we report the development and validation of a new mouse disc organ culture system by dynamically applying compression loading in a customized micro-culture device tailored for mouse lumbar discs. Precise axial compression force was delivered by a computer-controlled system consisting of a robust micromechanical linear actuator, a force sensitive resistor, and a precision micro-stepping machinery. Customized PDMS-based loading chambers allowed simultaneous loading of six discs per regimen, which streamlined the workflow to reach sufficient statistic power. The detrimental loading regimen of mouse lumbar discs...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 15, 2020 Category: Materials Science Authors: Xing Y, Zhang P, Zhang Y, Holzer L, Xiao L, He Y, Majumdar R, Huo J, Yu X, Ramasubramanian MK, Jin L, Wang Y, Li X, Oberholzer J Tags: J Mech Behav Biomed Mater Source Type: research

Surface modification of polymer textile biomaterials by N2 supercritical jet: Preliminary mechanical and biological performance assessment.
Abstract Foreign Body Reaction (FBR) is a critical issue to be addressed when polyethylene terephthalate (PET) textile implants are considered in the medical field to treat pathologies involving hernia repair, revascularization strategies in arterial disease, and aneurysm or heart valve replacement. The natural porosity of textile materials tends to induce exaggerated tissue ingrowth which may prevent the implants from remaining flexible. One hypothesized way to limit the FBR process is to increase the material surface roughness at the yarn level. Supercritical N2 (ScN2) jet particle projection is a technique that...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 7, 2020 Category: Materials Science Authors: Khoffi F, Khalsi Y, Chevrier J, Kerdjoudj H, Tazibt A, Heim F Tags: J Mech Behav Biomed Mater Source Type: research

Topological optimization of 3D printed bone analog with PEKK for surgical mandibular reconstruction.
CONCLUSIONS: The 3D printed bone analog with topological optimization is patient-specific and has advantages over the conventional fibular bone graft for surgical mandibular reconstruction. The optimized PEKK bone analog model creates more normal stress-strain trajectories than the fibular graft model and likely provides better functional and cosmetic outcomes. PMID: 32279058 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 5, 2020 Category: Materials Science Authors: Cheng KJ, Liu YF, Wang R, Zhang JX, Jiang XF, Dong XT, Xu X Tags: J Mech Behav Biomed Mater Source Type: research

Characterization of arterial flow mediated dilation via a physics-based model.
Abstract In this paper, a physics-based mathematical model is developed to describe the transient behavior of the brachial artery during the Flow Mediated Dilation (FMD) test. The change of the artery's diameter was collected for 7 cases via in vivo, non-invasive ultrasound imaging. A theoretical model was developed to capture the response of the blood vessel to the change of the blood flow, in which the vessel's compliance is modeled as a function of the wall shear stress (WSS). The theory precisely captures the key feature of the mechanotransduction process, which a conventional viscoelastic model fails to descr...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 5, 2020 Category: Materials Science Authors: Sidnawi B, Chen Z, Sehgal C, Wu Q Tags: J Mech Behav Biomed Mater Source Type: research

In-vitro polishing of CAD/CAM ceramic restorations: An evaluation with SEM and confocal profilometry.
CONCLUSION: The surface roughness of ZIR, LS and FC crowns after the use of chairside polishing kits was comparable with the roughness measured before occlusal adjustment. A two-step procedure showed as good results as a three-step process. A smoother surface was obtained for ZIR and LS compared to FC with both polishing protocols. PMID: 32276187 [PubMed - as supplied by publisher] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 3, 2020 Category: Materials Science Authors: Scherrer D, Bragger U, Ferrari M, Mocker A, Joda T Tags: J Mech Behav Biomed Mater Source Type: research

Structural, chemical and optical characterizations of an experimental SiO2-Y-TZP ceramic produced by the uniaxial/isostatic pressing technique.
This study aimed to produce a new SiO2+Y-TZP ceramic via uniaxial/isostatic compression that was structurally and chemically characterized relating to its translucency and flexural strength. SiO2 and Y-TZP were mixed using a ball mill, pressed and sintered at 1150 °C. The optical and mechanical properties of the specimens were compared to lithium disilicate (LD) and zirconia-reinforced lithium silicate (ZLS) (Kruskal-Wallis, α = 0.05). The Fourier Transform Infrared Spectroscopy bands suggested an interaction between Si, O and Zr. Contrast ratio and translucency parameter of the experimental cerami...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 1, 2020 Category: Materials Science Authors: Mosquim V, Ferrairo BM, Vertuan M, Magdalena AG, Fortulan CA, Lisboa-Filho PN, Cesar PF, Bonfante EA, Honório HM, Sanches Borges AF Tags: J Mech Behav Biomed Mater Source Type: research

Hydration related changes in tensile response of posterior porcine sclera.
Abstract It has been shown that there exists significance dependence between hydration and biomechanical properties of hydrated tissues such as cornea. The primary purpose of this study was to determine hydration effects on mechanical properties of sclera. Scleral strips, dissected from the posterior part of pig eyes along the superior-inferior direction, were divided into four hydration groups by first drying them and then soaking them in PBS until their hydration reached to 75%, 100%, 150%, and 200%. The strips were subjected to ten consecutive cycles of loading and unloading up to 1 MPa. The response of sa...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 18, 2020 Category: Materials Science Authors: Hatami-Marbini H, Pachenari M Tags: J Mech Behav Biomed Mater Source Type: research

How does stent expansion alter drug transport properties of the arterial wall?
cute;nez MA Abstract Stents have become the most successful device to treat advanced atherosclerotic lesions. However, one of the main issues with these interventions is the development of restenosis. The coating of stents with antiproliferative substances to reduce this effect is now standard, although such drugs can also delay re-endothelialization of the intima. The drug release strategy is therefore a key determinant of drug-eluting stent efficacy. Many mathematical models describing drug transport in arteries have been developed and, usually separately, models describing the mechanics of arterial tissue have ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 18, 2020 Category: Materials Science Authors: Escuer J, Cebollero M, Peña E, McGinty S, Martínez MA Tags: J Mech Behav Biomed Mater Source Type: research

Service life characterization of orthopedic implant material made of ultra-high molecular weight polyethylene under physiological conditions.
PMID: 32174385 [PubMed - in process] (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 18, 2020 Category: Materials Science Authors: Wegner N, Scholz R, Knyazeva M, Walther F Tags: J Mech Behav Biomed Mater Source Type: research