Immature porcine cortical bone mechanical properties and composition change with maturation and displacement rate
The objective of this study was to characterize the evolution of tissue-level mechanical behavior, composition, and microstructure of maturing cortical porcine bone with uniaxial tension, Raman spectroscopy, and light microscopy as a function of maturation. We asked: 1) How do the monotonic uniaxial tensile properties change with maturation and displacement rate; 2) How does the composition and microstructure change with maturation; and 3) Is there a correlation between composition and tensile properties with maturation? Elastic modulus (p < 0.001), fracture stress (p < 0.001), and energy absorption (p < 0.014) in...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 15, 2024 Category: Materials Science Authors: Emily Szabo Jay Bensusan Ozan Akkus Clare Rimnac Source Type: research

The effect of triglycerol diacrylate on the printability and properties of UV curable, bio-based nanohydroxyapatite composites
This study demonstrates the development of bio-based additive manufacturing feedstocks for potential uses in sustainable manufacturing, rapid prototyping, and biomaterial applications.PMID:38490049 | DOI:10.1016/j.jmbbm.2024.106499 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 15, 2024 Category: Materials Science Authors: Elizabeth V Diederichs Dibakar Mondal Haresh Patil Maud Gorbet Thomas L Willett Source Type: research

Tunable structure and linear viscoelastic properties of poly(glycerol adipate urethane)-based elastomeric composites for tissue regeneration
J Mech Behav Biomed Mater. 2024 Mar 2;153:106493. doi: 10.1016/j.jmbbm.2024.106493. Online ahead of print.ABSTRACTElastomeric biocomposites based on poly(glycerol adipate urethane) and hydroxyapatite were fabricated for tissue regeneration. The poly(glycerol adipate urethane) (PGAU) elastomeric composite matrices were obtained by chemical crosslinking of the poly(glycerol adipate) prepolymer (pPGA) with diisocyanate derivative of L-lysine. Two series of composites varying in the amount of L-lysine diisocyanate ethyl ester (LDI) used as a crosslinking agent were manufactured. As a ceramic filler both unmodified and L-lysine...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 14, 2024 Category: Materials Science Authors: Ma łgorzata Anna Gazińska Anna Krokos Source Type: research

Fabrication and characterization of a bioactive composite scaffold based on polymeric collagen/gelatin/nano β-TCP for alveolar bone regeneration
This study aimed to fabricate and characterize the freeze-dried bone regeneration scaffolds composed of polymeric Type I collagen, nano Beta-tricalcium phosphate (β-TCP), and gelatin. The stable structures of scaffolds were obtained by thermal crosslinking and EDC/NHS ((1-ethyl-3-(3-dimethylaminopropyl) carbodiimide)/(N-hydroxysuccinimide)) chemical crosslinking processes. Subsequently, the physicochemical and biological properties of the scaffolds were characterized and assessed. The results indicated the bioactive composite scaffolds containing 10% and 20% (w/v) nano β-TCP exhibited suitable porosity (84.45 ± 25.43 nm...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 14, 2024 Category: Materials Science Authors: Chao Yao Prisana Pripatnanont Junbiao Zhang Srisurang Suttapreyasri Source Type: research

Experimental characterization of residual deformations in human descending thoracic aortas
J Mech Behav Biomed Mater. 2024 Mar 2;153:106492. doi: 10.1016/j.jmbbm.2024.106492. Online ahead of print.ABSTRACTThe effect of residual stresses on the deformation of human aortas under pulsatile pressure is relevant. Experimental measurements of residual deformations are necessary to characterize residual stresses in human aortas. For this reason, an experimental study is carried out. In the present study, longitudinal and circumferential strips from descending thoracic aortas obtained from 21 donors, harvested during organ donation explant, underwent residual deformation measurements. The intact wall and the three separ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 13, 2024 Category: Materials Science Authors: Marco Amabili Giulio Franchini Rinaldo Garziera Source Type: research

Experimental characterization of residual deformations in human descending thoracic aortas
J Mech Behav Biomed Mater. 2024 Mar 2;153:106492. doi: 10.1016/j.jmbbm.2024.106492. Online ahead of print.ABSTRACTThe effect of residual stresses on the deformation of human aortas under pulsatile pressure is relevant. Experimental measurements of residual deformations are necessary to characterize residual stresses in human aortas. For this reason, an experimental study is carried out. In the present study, longitudinal and circumferential strips from descending thoracic aortas obtained from 21 donors, harvested during organ donation explant, underwent residual deformation measurements. The intact wall and the three separ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 13, 2024 Category: Materials Science Authors: Marco Amabili Giulio Franchini Rinaldo Garziera Source Type: research

Implementing Machine Learning approaches for accelerated prediction of bone strain in acetabulum of a hip joint
J Mech Behav Biomed Mater. 2024 Mar 2;153:106495. doi: 10.1016/j.jmbbm.2024.106495. Online ahead of print.ABSTRACTThe Finite Element (FE) methods for biomechanical analysis involving implant design and subject parameters for musculoskeletal applications are extensively reported in literature. Such an approach is manually intensive and computationally expensive with longer simulations times. Although Artificial Intelligence (AI) based approaches are implemented to a limited extent in biomechanics, such approaches to predict bone strain in acetabulum of a hip joint, are hardly explored. In this context, the primary objective...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: Gowtham Nimmal Haribabu Bikramjit Basu Source Type: research

Additively-manufactured Mg wire-reinforced PLDL-matrix composites for biomedical applications
J Mech Behav Biomed Mater. 2024 Mar 2;153:106496. doi: 10.1016/j.jmbbm.2024.106496. Online ahead of print.ABSTRACTCoupons of a medical grade PLDL polymer matrix uniaxially reinforced with a 15% volume fraction of Mg wires have been manufactured by fused filament fabrication for the first time. Two different types of Mg wires, without and with a surface treatment by plasma electrolytic oxidation were used. Both composite materials were subjected to degradation in phosphate buffer solution over a 3-week period, and their degradation and deformation micromechanisms were analysed in detail. Additionally, the materials were sub...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: C Thompson C Gonz ález J LLorca Source Type: research

Implementing Machine Learning approaches for accelerated prediction of bone strain in acetabulum of a hip joint
J Mech Behav Biomed Mater. 2024 Mar 2;153:106495. doi: 10.1016/j.jmbbm.2024.106495. Online ahead of print.ABSTRACTThe Finite Element (FE) methods for biomechanical analysis involving implant design and subject parameters for musculoskeletal applications are extensively reported in literature. Such an approach is manually intensive and computationally expensive with longer simulations times. Although Artificial Intelligence (AI) based approaches are implemented to a limited extent in biomechanics, such approaches to predict bone strain in acetabulum of a hip joint, are hardly explored. In this context, the primary objective...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: Gowtham Nimmal Haribabu Bikramjit Basu Source Type: research

Additively-manufactured Mg wire-reinforced PLDL-matrix composites for biomedical applications
J Mech Behav Biomed Mater. 2024 Mar 2;153:106496. doi: 10.1016/j.jmbbm.2024.106496. Online ahead of print.ABSTRACTCoupons of a medical grade PLDL polymer matrix uniaxially reinforced with a 15% volume fraction of Mg wires have been manufactured by fused filament fabrication for the first time. Two different types of Mg wires, without and with a surface treatment by plasma electrolytic oxidation were used. Both composite materials were subjected to degradation in phosphate buffer solution over a 3-week period, and their degradation and deformation micromechanisms were analysed in detail. Additionally, the materials were sub...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: C Thompson C Gonz ález J LLorca Source Type: research

Implementing Machine Learning approaches for accelerated prediction of bone strain in acetabulum of a hip joint
J Mech Behav Biomed Mater. 2024 Mar 2;153:106495. doi: 10.1016/j.jmbbm.2024.106495. Online ahead of print.ABSTRACTThe Finite Element (FE) methods for biomechanical analysis involving implant design and subject parameters for musculoskeletal applications are extensively reported in literature. Such an approach is manually intensive and computationally expensive with longer simulations times. Although Artificial Intelligence (AI) based approaches are implemented to a limited extent in biomechanics, such approaches to predict bone strain in acetabulum of a hip joint, are hardly explored. In this context, the primary objective...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: Gowtham Nimmal Haribabu Bikramjit Basu Source Type: research

Additively-manufactured Mg wire-reinforced PLDL-matrix composites for biomedical applications
J Mech Behav Biomed Mater. 2024 Mar 2;153:106496. doi: 10.1016/j.jmbbm.2024.106496. Online ahead of print.ABSTRACTCoupons of a medical grade PLDL polymer matrix uniaxially reinforced with a 15% volume fraction of Mg wires have been manufactured by fused filament fabrication for the first time. Two different types of Mg wires, without and with a surface treatment by plasma electrolytic oxidation were used. Both composite materials were subjected to degradation in phosphate buffer solution over a 3-week period, and their degradation and deformation micromechanisms were analysed in detail. Additionally, the materials were sub...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: C Thompson C Gonz ález J LLorca Source Type: research

Implementing Machine Learning approaches for accelerated prediction of bone strain in acetabulum of a hip joint
J Mech Behav Biomed Mater. 2024 Mar 2;153:106495. doi: 10.1016/j.jmbbm.2024.106495. Online ahead of print.ABSTRACTThe Finite Element (FE) methods for biomechanical analysis involving implant design and subject parameters for musculoskeletal applications are extensively reported in literature. Such an approach is manually intensive and computationally expensive with longer simulations times. Although Artificial Intelligence (AI) based approaches are implemented to a limited extent in biomechanics, such approaches to predict bone strain in acetabulum of a hip joint, are hardly explored. In this context, the primary objective...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: Gowtham Nimmal Haribabu Bikramjit Basu Source Type: research

Additively-manufactured Mg wire-reinforced PLDL-matrix composites for biomedical applications
J Mech Behav Biomed Mater. 2024 Mar 2;153:106496. doi: 10.1016/j.jmbbm.2024.106496. Online ahead of print.ABSTRACTCoupons of a medical grade PLDL polymer matrix uniaxially reinforced with a 15% volume fraction of Mg wires have been manufactured by fused filament fabrication for the first time. Two different types of Mg wires, without and with a surface treatment by plasma electrolytic oxidation were used. Both composite materials were subjected to degradation in phosphate buffer solution over a 3-week period, and their degradation and deformation micromechanisms were analysed in detail. Additionally, the materials were sub...
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 9, 2024 Category: Materials Science Authors: C Thompson C Gonz ález J LLorca Source Type: research

Influence of coating dental enamel with a TiF < sub > 4 < /sub > -loaded polymeric primer on the adverse effects caused by a bleaching gel with 35% H < sub > 2 < /sub > O < sub > 2 < /sub >
CONCLUSION: Coating enamel with a PPol containing TiF4 before applying a 35% BG may increase enamel microhardness and esthetic efficacy and reduce the trans-amelodentinal cytotoxicity of conventional in-office tooth bleaching. The PPol containing 10 mg/mL of TiF4 promoted the best outcomes.PMID:38458078 | DOI:10.1016/j.jmbbm.2024.106497 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - March 8, 2024 Category: Materials Science Authors: Vict ória Peruchi Rafael Antonio de Oliveira Ribeiro Igor Paulino Mendes Soares L ídia de Oliveira Fernandes Juliana Rios de Oliveira Maria Luiza Barucci Ara újo Pires Josimeri Hebling Diana Gabriela Soares Carlos Alberto de Souza Costa Source Type: research