Sjogren's Syndrome Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The OSCAR-MP Consensus Criteria for Quality Assessment of Retinal Optical Coherence Tomography Angiography
Discussion We propose a 3-step approach for standardized quality control: (1) To define a specific ROI, (2) to assess the occurrence of OCTA artifacts according to the OSCAR-MP criteria, and (3) to evaluate OCTA quality based on the occurrence of different artifacts within the ROI. OSCAR-MP OCTA QC criteria achieved high interrater agreement in an international multicenter study and is a promising QC protocol for application in the context of future clinical trials and studies. (Source: Neurology Neuroimmunology and Neuroinflammation)
Source: Neurology Neuroimmunology and Neuroinflammation - October 9, 2023 Category: Neurology Authors: Wicklein, R., Yam, C., Noll, C., Aly, L., Banze, N., Romahn, E. F., Wolf, E., Hemmer, B., Oertel, F. C., Zimmermann, H., Albrecht, P., Ringelstein, M., Baumann, C., Feucht, N., Penkava, J., Havla, J., Gernert, J. A., Mardin, C., Vasileiou, E. S., Van Der Tags: All Imaging, Retina, Multiple sclerosis Research Article Source Type: research

Sexual health in women with Sjogren's syndrome: A review
CONCLUSIONS: In summary, certain aspects of sexual health (sexual function, sex hormones and pregnancy outcomes) are impaired in SS women. Screening for sexual health problems in SS female should become an integral part of medical clinical practice. Rheumatologists should be aware of this association and collaborate with gynecologists, obstetricians, psychologists, and other experts on this issue to determine appropriate therapeutic approaches.PMID:37801781 | DOI:10.1016/j.ejogrb.2023.09.025 (Source: Reproductive Biology)
Source: Reproductive Biology - October 6, 2023 Category: Reproduction Medicine Authors: Yang Yang Xin-Xiang Huang Rong-Xiu Huo Jin-Ying Lin Source Type: research

Oral microbial biomap in the drought environment: Sjogren's syndrome
AbstractSjogren's syndrome (SS) is an autoimmune disease that affects primarily the salivary glands, making perturbations in the oral ecosystem and potential factors of salivary flow that influence the onset and development of the disease. The oral cavity contains diverse microorganisms that inhabit various niches such as the oral microbial “biomap.” It does not seem specific enough to establish a characteristic microbiome, given the diversity of clinical manifestations, variable rates of salivary secretion, and influential risk factors in patients with SS. This review discusses the biogeography of the oral microbio...
Source: Molecular Oral Microbiology - September 29, 2023 Category: Microbiology Authors: Laura Bustos ‐Lobato, Maria J. Rus, Carlos Saúco, Aurea Simon‐Soro Tags: REVIEW ARTICLE Source Type: research

Evaluation of ocular neuropathic pain
CONCLUSION: Ocular pain questionnaires can potentially diagnose ocular neuropathic pain. Disease-specific questionnaires are limited to their target populations, and non-disease-specific ophthalmic questionnaires are unreliable. Further studies are required to determine the most appropriate questionnaire to evaluate ocular neuropathic pain.PMID:37748645 | DOI:10.1016/j.jtos.2023.09.009 (Source: The Ocular Surface)
Source: The Ocular Surface - September 25, 2023 Category: Opthalmology Authors: Damien Tuan-Man Le Himal Kandel Stephanie L Watson Source Type: research

Research progress on the clinical application and mechanism of iguratimod in the treatment of autoimmune diseases and rheumatic diseases
Autoimmune diseases are affected by complex pathophysiology involving multiple cell types, cytokines, antibodies and mimicking factors. Different drugs are used to improve these autoimmune responses, including nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, antibodies, and small molecule drugs (DMARDs), which are prevalent clinically in the treatment of rheumatoid arthritis (RA), etc. However, low cost-effectiveness, reduced efficacy, adverse effects, and patient non-response are unattractive factors driving the development of new drugs such as iguratimod. As a new disease-modifying antirheumatic drug, igur...
Source: Frontiers in Immunology - September 21, 2023 Category: Allergy & Immunology Source Type: research

Requirements for anti ‐aquaporin 5 autoantibody production in a mouse model
This study aimed to understand the antigenic characteristics that induce autoantibodies against an AQP5 “E” epitope (AQP5E) in a mouse model using C57BL/6 mice. Immunization with a PmE-L peptide derived from Pm AQP, which contains amino acid mismatches both at the B- and T-cell epitopes, efficiently induced anti-AQP5E autoantibodies accompanied by increased germinal center (GC) B and follicular he lper T cells in the draining lymph nodes. However, PmE, a peptide lacking a T-cell epitope, and AQP5E-L, an AQP5-derived self-peptide, hardly induced either anti-AQP5E autoantibodies or GC responses. Surprisingly, OTII-AQP5E,...
Source: Molecular Oral Microbiology - September 19, 2023 Category: Microbiology Authors: Sabin Acharya, Ahreum Lee, Hyunjin Kim, Hyeong ‐jin Kim, Youngnim Choi Tags: ORIGINAL ARTICLE Source Type: research

Clinicopathological characteristics and prognosis of lupus nephritis patients with acute kidney injury
CONCLUSIONS: LN patients with AKI stage 3, but not stage 1 and 2, have poorer long-term renal outcomes and patient survival. Our study demonstrates the importance of early identification and management of AKI in LN patients.PMID:37708856 | DOI:10.1159/000533847 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Suchun Li Qimei Luo Yuting Fan Chen Zhao Fengxian Huang Xi Xia Wei Chen Source Type: research

B Cells Clonality and Primary Sjogren Syndrome: Comment on the article by Arvidsson, et al.
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - September 11, 2023 Category: Rheumatology Authors: Ranjeet Singh Mahla Tags: Letters Source Type: research