Fight Aging! Newsletter, January 8th 2024
This study examined whether the local injection of the supernatant of activated PRP (saPRP) into the salivary gland (SG) could help prevent aging-induced SG dysfunction and explored the mechanisms responsible for the protective effects on the SG hypofunction. Human salivary gland epithelial cells (hSGEC) were treated with saPRP or PRP after senescence through irradiation. The significant proliferation of hSGEC was observed in saPRP treated group compared to irradiation only group and irradiation + PRP group. Cellular senescence, apoptosis, and inflammation were significantly reduced in the saPRP group. Th...
Source: Fight Aging! - January 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Platelet Rich Plasma Treatment Rescues Damaged Salivary Gland Function in Aged Mice
This study examined whether the local injection of the supernatant of activated PRP (saPRP) into the salivary gland (SG) could help prevent aging-induced SG dysfunction and explored the mechanisms responsible for the protective effects on the SG hypofunction. Human salivary gland epithelial cells (hSGEC) were treated with saPRP or PRP after senescence through irradiation. The significant proliferation of hSGEC was observed in saPRP treated group compared to irradiation only group and irradiation + PRP group. Cellular senescence, apoptosis, and inflammation were significantly reduced in the saPRP group. ...
Source: Fight Aging! - January 5, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Ailments and Their Add-ons
You get one ailment, and it always seems to bring along its ' friends ' . A few examples are cancer with chemotherapy causes digestive issuesand temporary baldness. It can sometimes also cause long term cardiac issues - which can eventually kill you. With rheumatoid arthritis you can get things like Sjogren ' s Syndrome which causes dry eyes and other fun things. Afew examples are:" ... [RA]inflammation can result in conditions affecting skin, heart, lung, eyes, mental health, etc. Conditions likeosteoporosis, cataracts,depression, cancers, etc. are more common. And add to that infection based conditions like influenza, p...
Source: Caroline's Breast Cancer Blog - August 21, 2017 Category: Cancer & Oncology Tags: ailments being a patient comorbidities Source Type: blogs

Pulmonary manifestations of Sjogren's syndrome
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - September 20, 2016 Category: Internal Medicine Tags: pulmonary rheumatology Source Type: blogs

Fight Aging! Newsletter, August 29th 2016
This study demonstrates that TNTs play a significant part in the intercellular transfer of α-synuclein fibrils and reveals the specific role of lysosomes in this process. This represents a major breakthrough in understanding the mechanisms underlying the progression of synucleinopathies. These compelling findings, together with previous reports from the same team, point to the general role of TNTs in the propagation of prion-like proteins in neurodegenerative diseases and identify TNTs as a new therapeutic target to combat the progression of these incurable diseases. Shorter Period of Rapamycin Treatment in Mice...
Source: Fight Aging! - August 28, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards a Regenerative Therapy for the Lacrimal Gland and Dry Eyes
In this study, the researchers used progenitor cells that were poised to become epithelial tissue, a key component of the lacrimal gland. The researchers knew they faced a major challenge: sorting and separating "sticky" epithelial cell progenitors without destroying them. "We had to figure out how to dissociate the tissue into single cells without completely obliterating everything." The researchers solved this problem by developing markers to label the cells of interest and then testing different enzymes and other reagents to draw them out of tissues. With these cells in hand, the researchers injected them into th...
Source: Fight Aging! - August 22, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fighting Back - How 5 Famous People Overcame Autoimmune Diseases
Ever wondered what Rheumatoid Arthritis or Multiple Sclerosis really are? Have you ever heard of Sjogren's Syndrome or Psoriatic Arthritis? All these strange-sounding diseases and many more are classified as autoimmune diseases.Contributor: Sandra GreenPublished: Jan 04, 2013 (Source: Most Recent Health Wellness - Associated Content)
Source: Most Recent Health Wellness - Associated Content - January 4, 2013 Category: Other Conditions Source Type: blogs