The proportion of CD161 on CD56+ NK cells in peripheral circulation associates with clinical features and disease activity of primary Sj ögren's syndrome
ConclusionThis study suggested that the proportion of CD56+ NK cells and CD161+CD56+ NK cells decreased significantly in pSS patients, and the proportion of CD161+CD56+ NK cells negatively associated with the clinical features and disease activity of pSS patients. CD161 expression inhibited the function of CD56+ NK cells in peripheral blood of pSS patients. The CD161+CD56+ NK cells may present as a potential target for therapy and a biomarker of disease activity in pSS. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 5, 2024 Category: Allergy & Immunology Authors: Ping Zhao, Yanhong Yang, Saizhe Song, Wei Cheng, Cheng Peng, Xin Chang, Jian Wu, Cuiping Liu Tags: ORIGINAL ARTICLE Source Type: research

Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
CONCLUSIONS: Both KRG and placebo groups showed significant reductions in fatigue. KRG treatment for 24 weeks did not reduce fatigue symptoms more than the placebo in patients with rheumatic diseases.PMID:38576235 | DOI:10.3904/kjim.2023.350 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 5, 2024 Category: Internal Medicine Authors: Soo-Kyung Cho Yeo-Jin Song Jung-Yong Han Hye Won Kim Eunwoo Nam Yoon-Kyoung Sung Source Type: research

Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
CONCLUSIONS: Both KRG and placebo groups showed significant reductions in fatigue. KRG treatment for 24 weeks did not reduce fatigue symptoms more than the placebo in patients with rheumatic diseases.PMID:38576235 | DOI:10.3904/kjim.2023.350 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 5, 2024 Category: Internal Medicine Authors: Soo-Kyung Cho Yeo-Jin Song Jung-Yong Han Hye Won Kim Eunwoo Nam Yoon-Kyoung Sung Source Type: research

Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
CONCLUSIONS: Both KRG and placebo groups showed significant reductions in fatigue. KRG treatment for 24 weeks did not reduce fatigue symptoms more than the placebo in patients with rheumatic diseases.PMID:38576235 | DOI:10.3904/kjim.2023.350 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 5, 2024 Category: Internal Medicine Authors: Soo-Kyung Cho Yeo-Jin Song Jung-Yong Han Hye Won Kim Eunwoo Nam Yoon-Kyoung Sung Source Type: research

Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
CONCLUSIONS: Both KRG and placebo groups showed significant reductions in fatigue. KRG treatment for 24 weeks did not reduce fatigue symptoms more than the placebo in patients with rheumatic diseases.PMID:38576235 | DOI:10.3904/kjim.2023.350 (Source: The Korean Journal of Internal Medicine)
Source: The Korean Journal of Internal Medicine - April 5, 2024 Category: Internal Medicine Authors: Soo-Kyung Cho Yeo-Jin Song Jung-Yong Han Hye Won Kim Eunwoo Nam Yoon-Kyoung Sung Source Type: research

Downregulated GPX4 in salivary gland epithelial cells contributes to salivary secretion dysfunction in Sjogren's syndrome via lipid ROS/pSTAT4/AQP5 axis
This study unraveled novel targets to revitalize the salivary secretion function in SS patients.PMID:38574973 | DOI:10.1016/j.freeradbiomed.2024.04.003 (Source: Free Radical Biology and Medicine)
Source: Free Radical Biology and Medicine - April 4, 2024 Category: Biology Authors: Jiannan Zhou Janak L Pathak Lihong Wu Bo Chen Tingting Cao Wei Wei Xiaodan Wu Guiping Chen Nobumoto Watanabe Xiaomeng Li Jiang Li Source Type: research

Association of pulmonary hypertension with outcomes in patients with Systemic sclerosis and other connective tissue disorders: review and meta-analysis
CONCLUSIONS: Patients with SSc-PH are characterized by significantly lower survival function as compared to SSc patients without PH. Among the different entities of PH, SSc shows the worst survival, underlining prognostic significance of detection and evaluation of PH according to the currently established approach.PMID:38567564 | DOI:10.36141/svdld.v41i1.14570 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Maka Gegenava Tea Gegenava Source Type: research

Association of pulmonary hypertension with outcomes in patients with Systemic sclerosis and other connective tissue disorders: review and meta-analysis
CONCLUSIONS: Patients with SSc-PH are characterized by significantly lower survival function as compared to SSc patients without PH. Among the different entities of PH, SSc shows the worst survival, underlining prognostic significance of detection and evaluation of PH according to the currently established approach.PMID:38567564 | PMC:PMC11008328 | DOI:10.36141/svdld.v41i1.14570 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Maka Gegenava Tea Gegenava Source Type: research