Impact of the oral repercussions of Sjogren's Syndrome on patient's quality of life – a systematic review and meta-analysis
This study aimed to perform a systematic review to evaluate the impact of the oral repercussions of Sjogren's Syndrome (SS) on the quality of life (QoL) of patients living with this disease. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - March 20, 2024 Category: ENT & OMF Authors: Lauren Neumann Villarinho, Bruna Barcelos S ó, Lauren Frenzel Schuch, Felippe José Almeida Loureiro, Marco Antonio Trevizani Martins, Manoela Domingues Martins Source Type: research
Impact of the oral repercussions of Sjogren's Syndrome on patient's quality of life: a systematic review and meta-analysis
This study aimed to perform a systematic review to evaluate the impact of the oral repercussions of Sjogren's Syndrome (SS) on the quality of life (QoL) of patients living with this disease. To conduct this work, we followed the PRISMA guidelines. The included studies evaluated oral repercussions of SS and their correlation with QoL. The risk of bias was assessed with the JBI tools for each type of study design. Our findings resulted in 26 articles met the eligibility criteria. Seventeen articles (65.3%) used the OHIP-14 questionnaire to evaluate oral health-related QoL (OHRQoL) and showed that the oral repercussions of SS...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - March 20, 2024 Category: ENT & OMF Authors: Lauren Neumann Villarinho, Bruna Barcelos S ó, Lauren Frenzel Schuch, Felippe José Almeida Loureiro, Marco Antonio Trevizani Martins, Manoela Domingues Martins Source Type: research
An updated advancement of bifunctional IL-27 in inflammatory autoimmune diseases
Interleukin-27 (IL-27) is a member of the IL-12 family. The gene encoding IL-27 is located at chromosome 16p11. IL-27 is considered as a heterodimeric cytokine, which consists of Epstein–Barr virus (EBV)-induced gene 3 (Ebi3) and IL-27p28. Based on the function of IL-27, it binds to receptor IL-27rα or gp130 and then regulates downstream cascade. To date, findings show that the expression of IL-27 is abnormal in different inflammatory autoimmune diseases (including systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome, Behcet’s disease, inflammatory bowel disease, multiple sclerosis, systemic sclerosis,...
Source: Frontiers in Immunology - March 19, 2024 Category: Allergy & Immunology Source Type: research
