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Specialty: Cardiology
Condition: Cardiomyopathy

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Total 533 results found since Jan 2013.

Cardiac involvement, morbidity and mortality in hereditary transthyretin amyloidosis because of p.Glu89Gln mutation
Conclusion Cardiac involvement is common and has significant prognostic implications in the evaluated patients with p.Glu89Gln mutation. Heart failure and rhythm disturbances are the main causes of death. An earlier identification of the disease is crucial to improve prognosis.
Source: Journal of Cardiovascular Medicine - August 3, 2020 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Cardiac complications in inherited mitochondrial diseases
In this study, we looked at molecular genetics of MIDs and cardiac manifestations in patients with mitochondrial dysfunction.
Source: Heart Failure Reviews - July 28, 2020 Category: Cardiology Source Type: research

Current Treatment Options in Cardiovascular Medicine: Update on Reversible Cerebral Vasoconstriction Syndrome
ConclusionRCVS can now be accurately diagnosed using clinical and imaging features available upon presentation. Advances in knowledge about the risk factors, prognosis, and potential harmful effects of certain therapeutic strategies, are expected to optimize the management of this increasingly well recognized syndrome.
Source: Current Treatment Options in Cardiovascular Medicine - July 13, 2020 Category: Cardiology Source Type: research

Comparison of Complications and In-Hospital Mortality in Takotsubo (Apical Ballooning/Stress) Cardiomyopathy versus Acute Myocardial Infarction
There are limited data on the incidence of complications and in-hospital outcomes, among patients with Takotsubo cardiomyopathy (TC), as compared to acute myocardial infarction (AMI). From 2007-2014, a retrospective cohort of TC was compared to AMI using the National Inpatient Sample database. Complications were classified as acute heart failure, ventricular arrhythmic, cardiac arrest, high-grade atrioventricular block, mechanical, vascular/access, pericardial, stroke and acute kidney injury. Temporal trends, clinical characteristics and in-hospital outcomes were compared.
Source: The American Journal of Cardiology - July 12, 2020 Category: Cardiology Authors: Saraschandra Vallabhajosyula, Gregory W Barsness, Joerg Herrmann, Nandan S Anavekar, Rajiv Gulati, Abhiram Prasad Source Type: research

Biventricular imaging markers to predict outcomes in non ‐compaction cardiomyopathy: a machine learning study
ConclusionsOur findings show the importance of biventricular assessment to detect the severity of this cardiomyopathy and to plan for early clinical intervention. In addition, this study shows that even patients with normal LV function and negative late gadolinium enhancement had MACE. ML is a promising tool for analysing a large set of parameters to stratify and predict prognosis in LVNC patients.
Source: ESC Heart Failure - June 29, 2020 Category: Cardiology Authors: Camila Rocon, Mahdi Tabassian, Marcelo Dantas Tavares de Melo, Jose Arimateia Araujo Filho, Cesar Jos é Grupi, Jose Rodrigues Parga Filho, Edimar Alcides Bocchi, Jan D'hooge, Vera Maria Cury Salemi Tags: Original Research Article Source Type: research

Direct oral anticoagulants compared to vitamin K antagonist for the management of left ventricular thrombus
ConclusionsOur data suggest that DOACs are likely to be at least as effective and safe as VKA for stroke prevention in patients with LV thrombus and, despite their lack of a licence for this indication, are therefore likely to represent a reasonable and more convenient option for this setting. The optimal timing and type of anticoagulation for LV thrombus, as well as the role of screening for high ‐risk patients, should be tested in prospective, randomized trials.
Source: ESC Heart Failure - June 24, 2020 Category: Cardiology Authors: Hansa Iqbal, Sam Straw, Thomas P. Craven, Katherine Stirling, Stephen B. Wheatcroft, Klaus K. Witte Tags: Original Research Article Source Type: research

A Novel Extracorporeal Continuous-Flow Ventricular Assist System for Patients With Advanced Heart Failure 　- Initial Clinical Experience.
CONCLUSIONS: This novel extracorporeal VAD system with a hydrodynamically levitated centrifugal pump can safely and successfully bridge patients with advanced heart failure to subsequent therapeutic stages. PMID: 32461539 [PubMed - as supplied by publisher]
Source: Circulation Journal - May 27, 2020 Category: Cardiology Authors: Seguchi O, Fujita T, Kitahata N, Iwasaki K, Kuroda K, Nakajima S, Watanabe T, Yanase M, Fukushima S, Tsukiya T, Katagiri N, Mizuno T, Takewa Y, Hamasaki T, Onda K, Hayashi T, Yamamoto H, Tatsumi E, Kobayashi J, Fukushima N Tags: Circ J Source Type: research

Cardiovascular Magnetic Resonance and Sport Cardiology: a Growing Role in Clinical Dilemmas
AbstractExercise training induces morphological and functional cardiovascular adaptation known as the “athlete’s heart” with changes including dilatation, hypertrophy, and increased stroke volume. These changes may overlap with pathological appearances. Distinguishing athletic cardiac remodelling from cardiomyopathy is important and is a frequent medical dilemma. Cardiac magnetic resonance (CM R) has a role in clinical care as it can refine discrimination of health from a disease where ECG and echocardiography alone have left or generated uncertainty. CMR can more precisely assess cardiac structure and function as we...
Source: Journal of Cardiovascular Translational Research - May 19, 2020 Category: Cardiology Source Type: research

B-type natriuretic peptide and outcome in patients with apical hypertrophic cardiomyopathy.
CONCLUSIONS: Measuring BNP may help stratify the risk of HCM-related adverse outcome in apical HCM patients. PMID: 32439341 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - May 17, 2020 Category: Cardiology Authors: Shirotani S, Minami Y, Saito C, Haruki S, Hagiwara N Tags: J Cardiol Source Type: research

Atrial Fibrillation in Hypertrophic Cardiomyopathy: Evidence-based Review About Mechanism, Complications and Management
Hypertrophic cardiomyopathy (HCM) is 1 of the most frequent genetic cardiovascular diseases affecting 1 out of every 500 individuals in general population. Atrial Fibrillation incidences were 3.8% per 100 patients per year and overall prevalence among HCM patients are 27.09%. Higher risk of death noted in HCM patients with atrial fibrillation. Stroke and other thrombo embolic risks are increased in such patients. Medical management using mainly betablockers or amiodarone produced variable results and high rate of recurrence. Catheter ablation reduced symptom burden and complications despite moderate recurrence. Patients wi...
Source: Critical Pathways in Cardiology - May 16, 2020 Category: Cardiology Tags: Review Article Source Type: research

Outcome of patients receiving a continuous flow left ventricular assist device - a retrospective single center study.
Conclusions. Survival rates were good, although one third of patients were bridged with temporary circulatory support. We report a high level of freedom from pump thrombosis, fatal stroke, and driveline infection. PMID: 32292078 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - April 16, 2020 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

The role of echocardiography for diagnosis and prognostic stratification in hypertrophic cardiomyopathy
AbstractHypertrophic cardiomyopathy (HCM) is the most frequent cardiac disease with genetic substrate, affecting about 0.2 –0.5% of the population. While most of the patients with HCM have a relatively good prognosis, some are at increased risk of adverse events. Identifying such patients at risk is important for optimal treatment and follow-up. While clinical and electrocardiographic information plays an important ro le, echocardiography remains the cornerstone in assessing patients with HCM. In this review, we discuss the role of echocardiography in diagnosing HCM, the key features that differentiate HCM from other dis...
Source: Journal of Echocardiography - April 15, 2020 Category: Cardiology Source Type: research

Extent of Late Gadolinium Enhancement Predicts Thromboembolic Events in Patients With Hypertrophic Cardiomyopathy.
CONCLUSIONS: LGE extent (>14.4%) is an independent predictor for thromboembolic complications in patients with HCM and might therefore be considered as an important risk marker. The risk for thromboembolic events is significantly elevated if accompanied by AF. PMID: 32238665 [PubMed - as supplied by publisher]
Source: Circulation Journal - March 31, 2020 Category: Cardiology Authors: Hohneck A, Overhoff D, Doesch C, Sandberg R, Rudic B, Tueluemen E, Budjan J, Szabo K, Borggrefe M, Papavassiliu T Tags: Circ J Source Type: research

Relation of Advanced Interatrial Block to Risk of Atrial Fibrillation and Stroke
Advanced interatrial block (A-IAB) has been associated to atrial fibrillation (AF) and ischemic stroke, raising the question as to whether such patients, even when still in sinus rhythm without documented AF, could benefit from oral anticoagulation. AF and A-IAB are both markers of stroke. The anatomical substrate in both is fibrotic atrial cardiomyopathy, resulting in atrial electromechanical dyssynchrony, dysfunction, and left atrial remodelling, that favour blood stasis and hypercoagulation. Under these conditions thrombogenic cascade may be triggered, resulting in systemic embolization.
Source: The American Journal of Cardiology - March 16, 2020 Category: Cardiology Authors: Antoni Bay és-de-Luna, Manuel Martínez-Sellés, Roberto Elosua, Antoni Bayés-Genís, Guiomar Mendieta, Adrian Baranchuk, Günter Breithardt Source Type: research

Incidence, clinical characteristics, and risk factors of peripartum cardiomyopathy in Nigeria: results from the PEACE Registry
ConclusionsIn Nigeria, the burden of PPCM was greatest in the North –West zone, which has the highest known incidence. PPCM was predicted by sociodemographic factors and pre‐eclampsia, which should be considered in its control at population level. Postpartum customary birth practices and Hausa–Fulani ethnicity were not associated with PPCM in Nigeria.
Source: ESC Heart Failure - January 27, 2020 Category: Cardiology Authors: K.M. Karaye, N.A. Ishaq, H. Sa'idu, S.A. Balarabe, M.A. Talle, M.S. Isa, U.G. Adamu, H. Umar, H.I. Okolie, M.N. Shehu, I.Y. Mohammed, B. Sanni, O.S. Ogah, I. Oboirien, E.M. Umuerri, A.C. Mankwe, V.Y. Shidali, P. Njoku, S. Dodiyi ‐Manue Tags: Original Research Article Source Type: research