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Condition: Cardiomyopathy
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Total 1426 results found since Jan 2013.
To block or not to block: Targeting SK channels in diseased hearts
Atrial fibrillation (AF) is the most common arrhythmia, affecting more than 1% of general population and reaching over 10% in advanced age in the USA. Atrial fibrillation drastically increases the risk of stroke and promotes development of cardiomyopathy and congestive heart failure. Existing pharmacological approaches using β-blockers and inhibitors of Na+, Ca2+ and K+ channels to treat AF are effective only in 50% of cases. Furthermore, these drugs could affect ventricular tissue promoting proarrhythmic changes in electrical conduction, intracellular Ca2+ homeostasis, or action potential duration (APD).
Source: Journal of Molecular and Cellular Cardiology - September 22, 2023 Category: Cytology Authors: Dmitry Terentyev, Andriy E. Belevych, Bum-Rak Choi, Shanna Hamilton Source Type: research
The potential predictive value of cardiac mechanics for left ventricular reverse remodelling in dilated cardiomyopathy
ConclusionsPatients with LVRR had a lower LV volume index, lower LVSV index, lower LGE extent, higher LVRI, and preserved myocardial deformation in the longitudinal direction at baseline. LVRI and rGLPS at baseline were independent determinants of LVRR.
Source: ESC Heart Failure - September 12, 2023 Category: Cardiology Authors: Ao Kan,
Qimin Fang,
Shuhao Li,
Wenying Liu,
Xinwei Tao,
Kaiyao Huang,
Mengyao Hu,
Zhaofeng Feng,
Lianggeng Gong Tags: Original Article Source Type: research
Clinical Characteristics and Outcomes of Chagas Disease in the United States: A Multicenter Retrospective Analysis
Am J Trop Med Hyg. 2023 Sep 11:tpmd230361. doi: 10.4269/ajtmh.23-0361. Online ahead of print.ABSTRACTChagas disease affects approximately 300,000 patients in the United States. We evaluated a multicenter U.S.-based network to obtain clinical characteristics and outcomes of chronic Chagas disease by disease forms. This was a U.S.-based, multicenter, population-based, retrospective cohort study. We queried TriNetX, a global research network, to identify patients with dual-positive IgG serology for Trypanosoma cruzi. We captured outcomes of interest for up to 5 years. We found 429 patients with evidence of dual-positive T. cr...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Andr és F Henao-Martínez Christian Olivo-Freites Nelson I Agudelo Higuita Carolina Ferraz Carlos Franco-Paredes Jose Tuells Laila Woc-Colburn Salvador Villalpando-Carri ón Daniel B Chastain Anis Rassi Source Type: research
Starting Pediatric VAD Program: Transforming Challenges into Opportunities; A Case Series of a Single Center
CONCLUSIONS: To establish a VAD program, numerous specialties must be included with adequate training and learning for all team members.PMID:37679088 | DOI:10.59958/hsf.5545
Source: The Heart Surgery Forum - September 7, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Matija Bako š Milivoj Novak Dalibor Šarić Dorotea Bartoni ček Dra žen Belina Željko Đurić Darko Ani ć Željko Čolak Sanja Konosi ć Marina Mihalec Filip Rubi ć Toni Mati ć Goran Me đimurec Mislav Planinc Source Type: research
