Combination of transfemoral balloon-assisted tracking and the knuckle wire technique as a solution in a challenging urgent percutaneous coronary intervention
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

K.O.: a life-threatening punch. Report of a young patient experiencing anterior ST-elevation myocardial infarction after chest trauma
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Case reports Source Type: research

Myocardial infarction with nonobstructed coronary arteries following accidental nitrogen inhalation: diagnosis by cardiac magnetic resonance and coronary computed tomography
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Case reports Source Type: research

Baseline significant tricuspid regurgitation is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis
Introduction Significant tricuspid regurgitation is a well recognized indicator of right ventricular dysfunction. Recent studies have shown that significant tricuspid regurgitation is potentially associated with increased mortality in patients with severe aortic stenosis who underwent transcatheter aortic valve replacement (TAVR). However, data remained sparse and inconclusive. Thus, we performed a systematic review and meta-analysis of the literature to assess the association between significant tricuspid regurgitation and mortality in post TAVR patients. Hypothesis Significant tricuspid regurgitation is predictive f...
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Interventional cardiology. Structural heart disease Source Type: research

Angiographic performance of a novel sirolimus-coated balloon in native coronary lesions: the FAtebenefratelli SIrolimus COated NATIVES prospective registry
Conclusion The use of a novel SCB in native coronary arteries was associated with good angiographic outcome at 6-month follow-up. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Interventional cardiology. Coronary artery disease Source Type: research

The BIOFLOW-III Italian Satellite Registry: 18-month results of the Orsiro stent in an all-comer high-risk population
Conclusions The study results confirmed the excellent clinical performance of the Orsiro drug-eluting stents at 18 months in the whole all-comer population and in the prespecified high-risk subgroups. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Interventional cardiology. Coronary artery disease Source Type: research

The 12-lead ECG: a continuous reference for the cardiologist
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Editorial comment Source Type: research

ECG in dilated cardiomyopathy: specific findings and long-term prognostic significance
Conclusion The exhaustive systematic evaluation of ECG has an incremental impact in the prognostication of a large cohort of DCM patients, also regarding the arrhythmic stratification. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Clinical and prognostic association of total atrial conduction time in patients with heart failure: a report from Studies Investigating Co-morbidities Aggravating Heart Failure
Background The total atrial conduction time can be measured as the time from the onset of the P wave on the ECG to the peak of the A wave recorded at the mitral annulus using tissue Doppler imaging (A′; P-A′TDI); when prolonged, it might predict incident atrial fibrillation. Methods We measured P-A′TDI in outpatients with heart failure and sinus rhythm enrolled in the SICA-HF programme. Results P-A′TDI measured at the lateral mitral annulus was longer in patients with HF with reduced [LVEF50% and NT-proBNP > 125 ng/l, N = 71; 128 (108–145) ms; P = 0.026] compared to co...
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Global longitudinal strain in prosthesis-patient mismatch: relation to left ventricular mass regression and outcomes
This study was designed to investigate the association between the baseline global longitudinal strain (GLS) and the postoperative LVMR, and its relation to adverse outcomes. Methods A total of 316 patients with aortic stenosis undergoing isolated mechanical prosthesis implantation were screened, and data from 91 patients with aortic PPM and 165 non-PPM patients were retrospectively collected. All 256 patients underwent measurement of GLS by two-dimensional speckle-tracking echocardiography preoperatively, and were followed up for postoperative changes of LV mass index (LVMi) and other clinical outcomes. Results Duri...
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Imaging Source Type: research

Diagnostic utility of hybrid single photon emission computed tomography/computed tomography imaging in patients with Takotsubo syndrome
Conclusion In the majority of patients with TTS perfusion in SPECT was normal or only minor perfusion defect was observed. Application of CT attenuation correction did not change the final result of myocardial perfusion imaging; therefore, the CT component of the SPECT/CT study performed for attenuation correction is not useful for TTS diagnosis. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Imaging Source Type: research

Effects of postprandial hydroxytyrosol and derivates on oxidation of LDL, cardiometabolic state and gene expression: a nutrigenomic approach for cardiovascular prevention
Background and aim Cardiovascular diseases (CVDs) are the most frequent causes of death in the world. Inflammation and oxidative damage contribute significantly to the development of atherosclerosis and CVDs. European Food Safety Authority scientific opinion has acknowledged that hydroxytyrosol (3,4-dihydroxyphenylethanol) and derivatives, contained in extra virgin olive oil (EVOO), typically used in Mediterranean diet may play a crucial role in the reduction of the inflammatory pathway and in the prevention of CVDs. The aim of the study was to determine the effect in healthy volunteers of 25 g of phenols-rich EVOO (p-...
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Research articles: Prevention Source Type: research

Practical implementation of the Endocarditis Team in ‘functional’ reference centres: the Italian hospital network experience and recommendations of the Italian Society of Echocardiography and Cardiovascular Imaging
The 2015 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis recommend the use of a multidisciplinary team in the care of patients with infective endocarditis. A standardized collaborative approach should be implemented in centres with immediate access to different imaging techniques, cardiac surgery and health professionals from several specialties. This position paper has been produced by the Task Force for Management of Infective Endocarditis of Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI) with the aim of providing recommendations for the implementation...
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Position statement Source Type: research

May transcatheter aortic valve replacement become the preferred treatment over conventional surgery for elderly women with symptomatic severe aortic stenosis?
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 11, 2019 Category: Cardiology Tags: Editorial Source Type: research

Takotsubo cardiomyopathy: prognostication is affected by the underlying trigger: the reply
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Letters to the editor Source Type: research

Takotsubo cardiomyopathy: prognostication is affected by the underlying trigger
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Letters to the editor Source Type: research

Predictors of oedema in Tako-Tsubo cardiomyopathy: new insights into the diabetes paradox
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Research letter Source Type: research

Use of direct oral anticoagulants in very elderly patients: a case report of apixaban in an ultracentenary patient
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Case report Source Type: research

Left ventricular pseudo-aneurysm after transapical valve-in-valve transcatheter aortic valve replacement treated with percutaneous closure
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

A case of ‘resistant’ thrombus: all you can hit in very late stent thrombosis
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Differences in the extent of fibrosis in obstructive and nonobstructive hypertrophic cardiomyopathy
Aims Left ventricular outflow tract (LVOT) obstruction is a key feature of hypertrophic cardiomyopathy (HCM) that identifies patients at increased risk of adverse outcomes. Previous studies have hypothesized that LVOT obstruction enhances myocardial fibrosis and increases left ventricular (LV) filling pressures, producing greater clinical deterioration. However, this hypothesis has not been demonstrated in a clinical cohort comparing obstructive and nonobstructive patients. Methods Patients with HCM in whom Doppler echocardiography was performed within 30 days of cardiac MRI were enrolled, using the E/e′ ratio t...
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Torsemide versus furosemide and intermediate-term outcomes in patients with heart failure: an updated meta-analysis
Conclusion Torsemide is associated with a reduction in intermediate-term heart failure readmissions and improvement in New York Heart Association class compared with furosemide but is not associated with a reduced mortality risk. Additional randomized trials are needed to examine the impact of loop diuretics on clinical outcomes in patients with heart failure. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Prevalence and prognosis of lead masses in patients with cardiac implantable electronic devices without infection
Conclusion There is an evidence of clinical lead masses in asymptomatic patients with cardiac implantable electronic devices. The value of these findings is still debated for aetiological interpretation and for therapeutic strategy, but they are not necessarily associated with an infection. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Research articles: Imaging Source Type: research

Simplified three-dimensional spatial approach for improving confidence in reliably measuring left ventricular linear internal dimensions
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 3, 2019 Category: Cardiology Tags: Editorial Source Type: research

The difficult task of reducing symptom onset-to-balloon time among patients undergoing primary PCI
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research letter Source Type: research

Severe silent myocardial ischemia during echocardiographic examination in a patient during cardiac screening for a kidney transplant intervention
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Hidden culprit lesion: beyond coronary angiography
Coronary imaging is a useful tool to identify wall vessel disease also in the absence of obstructive stenosis. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Propensity-score-adjusted comparison of Evolut vs. Portico devices for transcatheter aortic valve implantation
Conclusion The acute and mid-term comparative safety and effectiveness of Evolut and Portico in experienced hands are similar, with the notable exception of a lower risk of permanent pacemaker implantation with Portico. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Structural heart intervention Source Type: research

Arrhythmic risk stratification in patients with dilated cardiomyopathy and intermediate left ventricular dysfunction
Conclusion A consistent quota of DCM patients with intermediate left ventricular dysfunction receiving OMT experienced SCD/MVA during follow-up. Left atrial dilatation and arrhythmogenic pattern were associated with a higher risk of SCD/MVA. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Virtual histology-intravascular ultrasound as a diagnostic alternative for morphological characterization of carotid plaque: comparison with histology and high-resolution magnetic resonance findings
Conclusion We believe that VH-IVUS may be useful when a quick intraprocedural evaluation of a carotid plaque before or after stent placement is required, but is not suitable for the accurate in-vivo differentiation between stable and unstable plaques prone to rupture, due to the suboptimal assessment of the necrotic component, fibrous cap thickness and rupture signs. We do believe, however, that these results need further evaluation in larger populations to be confirmed. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Predictors of in-hospital and long-term mortality in unselected patients admitted to a modern coronary care unit
Conclusion In our Level-2 ICCU, predictors of in-hospital and long-term mortality are similar to those commonly found in a Level-3 ICU. These data strongly suggest that ICUs dealing with acute cardiovascular patients should be reorganized with a necessary upgrading of competences and resources for medical and nursing staff. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

In-hospital and long-term outcomes of HIV-positive patients undergoing PCI according to kind of stent: a meta-analysis
Background Pathogenesis of cardiovascular disease in HIV-positive patients is related to the interaction between traditional and HIV-specific factors. Limited data are available regarding the prognosis of HIV-positive patients undergoing percutaneous coronary intervention (PCI). Methods All observational studies evaluating the prognosis of HIV-positive patients treated with PCI were included. In-hospital and long-term major adverse cardiac events (MACE) [composite endpoint of all-cause death or myocardial infarction (MI)] were the primary endpoints, whereas in-hospital and long-term all-cause death, cardiovascular dea...
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Drug-eluting compared to bare metal stents in patients with end-stage renal disease on dialysis: a meta-analysis
Conclusions Our meta-analysis shows a significant reduction in all-cause and cardiovascular mortality with the use of DES over BMS in dialyzed patients. Despite the lack of randomized studies, systematic use of DES in these high-risk patients should thus reasonably be considered as a first option in percutaneous coronary intervention candidates. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Impact of long-term therapy with acetylsalicylic acid on immature platelet count: a single-centre cohort study
Acetylsalicylic acid (ASA) represents one of the most widely used pharmacological treatments for the prevention of atherothrombotic events. However, its use in low-risk patients is still debated, due to the complex balance between benefits and bleeding complications, therefore requiring new tools for the assessment of cardiovascular risk. Immature platelet count (IPC) has been suggested as a marker of platelet reactivity and turnover, thus potentially reflecting the progression of the chronic atherothrombotic vascular damage, which could be prevented by ASA. However, no study has evaluated, so far, the impact of long-term ...
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Cardiac autonomic regulation in patients undergoing pulmonary vein isolation for atrial fibrillation
Conclusion Successful PVI may lead to transient autonomic alterations reflected by a reduction in pulse interval variability and BRS, with more prolonged changes in the Valsalva ratio. The efficacy of PVI in preventing atrial fibrillation recurrence seems to be related to transient parasympathetic atrial denervation. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research

Insertable cardiac monitor detection of silent atrial fibrillation in candidates for percutaneous patent foramen ovale closure
Conclusion An occult preexisting atrial fibrillation may lead to unnecessary percutaneous foramen ovale closure in a significant proportion of patients. A 6-month loop-recorder monitoring may improve the patient oriented decision-making. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research

Impact of β-thalassemia trait carrier state on inflammatory status in patients with newly diagnosed hypertension
Background B-thalassemia carrier state or thalassemia minor confers cardiovascular protection through favorable lipidemic and blood pressure profile. However, its impact on inflammatory status—a common denominator of the above conditions—has not been addressed. Methods We investigated a wide range of inflammatory markers [white blood cell (WBC) count, homocysteine, C-reactive protein (CRP), serum amyloid A (SAA), fibrinogen, plasminogen, fibronectin, plasminogen activator inhibitor-1 (PAI-1), and uric acid] in a large cohort of 15 805 newly diagnosed hypertensive patients (8299 men, 7506 women); 626 of t...
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Prevention Source Type: research

IGENDA protocol: gender differences in awareness, knowledge and perception of cardiovascular risk: An Italian multicenter study
Conclusion The present project could shed new light on the knowledge, awareness and perception of CVRFs and CVDs. If substantial differences will be detected by gender, the findings of this study may contribute to ultimately provide a new gender-oriented primary care approach inside the Italian healthcare system related to cardiovascular prevention and therapy strategies. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Research articles: Prevention Source Type: research

Occult bacteraemia in cardiac implantable electronic device patients: a review of diagnostic workflow and mandatory therapy
Cardiac implantable electronic device (CIED) implantation has greatly increased, with an associated exponential increase in CIED infections (CDIs). Cardiac device related infective endocarditis (CDRIE) has high morbidity and mortality: approximately 10–21%. Therefore, a prompt diagnosis and radical treatment of CDRIE are needed; transvenous lead extraction (TLE) is the mainstay for the complete healing, even if associated with wide logistic problems, high therapeutic costs and high mortality risk for patients. Some criticisms about the value of Duke criteria and their limitations for the diagnosis of CDRIE are known....
Source: Journal of Cardiovascular Medicine - April 2, 2019 Category: Cardiology Tags: Review Source Type: research

Atrial conduit function quantitation precardioversion predicts early arrhythmia recurrence in persistent atrial fibrillation patients
Aims Atrial fibrillation incidence is increasing due to ageing population and electrical cardioversion (ECV) is overused because of atrial fibrillation recurrences. Study's aim was to evaluate value of novel three-dimensional echocardiographic-derived left atrial conduit (LAC) function quantification in predicting early atrial fibrillation recurrence after ECV. Methods We included 106 patients [74 (64–78) years] who underwent ECV for persistent nonvalvular atrial fibrillation. For all clinical data and simultaneous left atrial and left ventricular (LV) three-dimensional full-volume data sets were available befor...
Source: Journal of Cardiovascular Medicine - March 7, 2019 Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research

Chronic thromboembolic pulmonary hypertension (CTEPH): what do we know about it? A comprehensive review of the literature
Chronic thromboembolic disease (CTED), especially when associated with pulmonary hypertension (CTEPH), is a fearsome and under-diagnosed but potentially curable complication of pulmonary embolism, thanks to recent therapeutic options. Aspecific symptoms and signs make its diagnosis challenging, requiring clinicians to be ready to suspect its presence in patients with dyspnea of unknown origin or persistent symptoms after acute pulmonary embolism. The aim of this review is to provide an update to the general practitioner or the specialist physician on the state of the art regarding the epidemiology, pathophysiology and clin...
Source: Journal of Cardiovascular Medicine - March 7, 2019 Category: Cardiology Tags: Review Source Type: research

Pre-transcatheter aortic valve implantation assessment in patients with renal failure: computed tomography and MRI acquisition protocols in our experience
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research letter Source Type: research

Rejection in heart transplantation for cardiac sarcoidosis mimicking idiopathic giant cell myocarditis: long-term follow-up
Heart transplantation is a life-saving therapy for some patients admitted for acute myocarditis. However, controversial exists about the major risk of rejection following heart transplantation in specific types of myocarditis. Because of relatively few data on the post heart transplant outcomes, we report the long-term follow-up of a 39-year-old patient with a previous history of ulcerative colitis, which rapidly worsened heart failure until an emergency heart transplant in 2004. The clinical course was complicated by many episodes of rejection; lastly, after the development of severe cardiac allograft vasculopathy, re-he...
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Endovascular repair in extra-anatomic bypass after hypoplastic aortic arch repair
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Improving health perception through a transition care model for adolescents with congenital heart disease
Aims The aim of this study was to assess the impact of a transition clinic model on adolescent congenital heart disease (CHD) patients’ health perception outcomes. The transition clinic model consists of multidisciplinary standardized interventions to educate and support CHD patients and represents a key element in the adequate delivery of care to these individuals during their transition from childhood to adulthood. Currently, empirical data regarding the impact of transition clinic models on the improvement of health perceptions in CHD adolescent patients are lacking. Methods A quasi-experimental design was em...
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research articles: Congenital heart disease Source Type: research

Intravascular ultrasound assisted carotid artery stenting: randomized controlled trial. Preliminary results on 60 patients
Conclusions Though not recommended as a routine intraprocedural evaluation, IVUS may be useful for a real-time CAS control when treating challenging plaques, such as ‘soft’ or lipidic ones or those prone to rupture, or whenever an intraprocedural morphologic evaluation is required for the appropriate stent choice, or when higher embolic risk is evaluated. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research articles: Editorial Source Type: research

No guts, no glory for aortic stenosis: impact of liver function on patients undergoing trascatheter aortic valve implantation
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research articles: Editorial Source Type: research

Meta-analysis of impact of liver disease on mortality after transcatheter aortic valve implantation
Aims To evaluate whether liver disease is associated with increased mortality after transcatheter aortic valve implantation (TAVI) and whether TAVI is associated with decreased mortality compared to surgical aortic valve replacement (SAVR) in patients with liver disease, we performed meta-analyses of currently available studies. Methods Studies reporting mortality in TAVI patients with liver disease versus those without liver disease and mortality after TAVI versus SAVR in patients with liver disease were eligible to be included. A relative risk (RR) or hazard ratio of mortality for TAVI patients with versus without l...
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research articles: Structural heart intervention Source Type: research

Transcathether aortic valve implantation with the new repositionable self-expandable Medtronic Evolut R vs. CoreValve system: evidence on the benefit of a meta-analytical approach
Conclusions The use of new-generation Evolut R was associated with improved procedural, functional and clinical outcomes compared with the CoreValve device. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research articles: Structural heart intervention Source Type: research

Identifying responders to oral iron supplementation in heart failure with a reduced ejection fraction: a post-hoc analysis of the IRONOUT-HF trial
Conclusion This study failed to identify a subset of responders more likely to derive a clinical benefit from oral iron therapy and does not support its routine use in patients with symptomatic HFrEF and iron deficiency. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 5, 2019 Category: Cardiology Tags: Research articles: Heart failure Source Type: research