Comparison of coronary artery bypass graft versus drug-eluting stents in dialysis patients: an updated systemic review and meta-analysis
Introduction As percutaneous coronary intervention (PCI) technologies have been far improved, we hence conducted an updated systemic review and meta-analysis to determine the comparability between coronary artery bypass graft (CABG) and PCI with drug-eluting stent (DES) in ESRD patients. Methods We comprehensively searched the databases of MEDLINE, EMBASE, PUBMED and the Cochrane from inception to January 2020. Included studies were published observational studies that compared the risk of cardiovascular outcomes among dialysis patients with CABG and DES. Data from each study were combined using the random-effec...
Source: Journal of Cardiovascular Medicine - March 10, 2021 Category: Cardiology Tags: Research articles: Interventions Source Type: research

Relationship between extreme obesity and mortality in patients with reduced ejection fraction
Aims Although obesity is associated with increased mortality, epidemiologic studies in heart failure have reported lower mortality in obese patients compared with matched nonobese patients (the ‘obesity paradox’). However, the relationship between survival and extreme (morbid) obesity (BMI ≥ 40) is poorly understood. We evaluate survival in low ejection fraction patients across a range of BMI categories, including extreme obesity. Methods In a retrospective review, 12 181 consecutive patients receiving nuclear stress testing at a tertiary care center were stratified based on BMI and ejection fraction...
Source: Journal of Cardiovascular Medicine - March 10, 2021 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Paradoxical effect of fat diet in matrix metalloproteinases induced mitochondrial dysfunction in diabetic cardiomyopathy
Conclusion Overall, these findings suggest novel therapeutic targets aimed to counteract mitochondrial dysfunction in the onset of diabetic cardiomyopathy. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 10, 2021 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Emerging therapy in light-chain and acquired transthyretin-related amyloidosis: an Italian single-centre experience in heart transplantation
Conclusion HTx may represent a valuable option in carefully selected patients. ASCT after HTx is an effective treatment that could decrease amyloidosis relapse in light-chain cardiac amyloidosis patients. A multidisciplinary approach is mandatory to select the best candidates and to obtain the most effective results with a specific surveillance follow-up protocol. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 10, 2021 Category: Cardiology Tags: Research articles: Heart failure Source Type: research

Managing patent foramen ovale in COVID-19 patients during and after viral infection: an unresolved matter
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - March 10, 2021 Category: Cardiology Tags: View point Source Type: research