Switching across direct oral anticoagulants: a real-life-setting pilot prospective study
Conclusion
DOAC-to-DOAC switch happens in 9% of patients using DOAC each year, and seems not to impact rates of cardiovascular events after switch. Dabigatran, in the elderly, might be associated with a higher risk of DOAC-to-DOAC switch. Further studies are needed to confirm the long-term safety and effectiveness of switching paradigm. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 1, 2021 Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research
Rate of venous thromboembolism and atrial fibrillation in a real-world case series of advanced cancer patients: the CaTEV Study
Conclusion
This study showed for cancer patients a considerably higher incidence of VTE and a comparable incidence of atrial fibrillation than reported in literature. Validated thromboembolic risk scores appear to be poorly predictive, and LMWH remains the most widely used anticoagulant drug. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 1, 2021 Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research
Prevention of cancer therapy-related heart failure, is it really possible?
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 1, 2021 Category: Cardiology Tags: Review: Editorial Source Type: research
Machine learning and network medicine: a novel approach for precision medicine and personalized therapy in cardiomyopathies
The early identification of pathogenic mechanisms is essential to predict the incidence and progression of cardiomyopathies and to plan appropriate preventive interventions. Noninvasive cardiac imaging such as cardiac computed tomography, cardiac magnetic resonance, and nuclear imaging plays an important role in diagnosis and management of cardiomyopathies and provides useful prognostic information.
Most molecular factors exert their functions by interacting with other cellular components, thus many diseases reflect perturbations of intracellular networks. Indeed, complex diseases and traits such as cardiomyopathies are...
Source: Journal of Cardiovascular Medicine - May 1, 2021 Category: Cardiology Tags: Review Source Type: research
Resilience and response of the congenital cardiac network in Italy during the COVID-19 pandemic: Erratum
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Erratum Source Type: research
Letter in reply to ‘Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper’
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Letters to the editor Source Type: research
Letter to the Editor: ‘Updated clinical evidence and place in therapy of bempedoic acid (BA) for hypercholesterolemia: aNMCO position paper’
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Letters to the editor Source Type: research
Outcome of extracorporeal membrane oxygenation support for high-risk percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Research letters Source Type: research
Unprotected left-main coronary percutaneous intervention in elderly: a retrospective analysis of practice and clinical outcome
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Research letters Source Type: research
Transient ST-segment elevation in coronavirus disease-2019
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Case reports Source Type: research
Mid-ventricular Takotsubo syndrome ‘lockdown’-related during coronavirus disease 2019 outbreak: a case report
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Case reports Source Type: research
Influence of ageing on circadian rhythm of heart rate variability in healthy subjects
Conclusion
A progressive physiological autonomic imbalance is present in ageing. The inverse trend in the relation between HRV parameters and age found in the senior group could be mainly due to a faster fluctuation of RR. This should be considered when studying changes in the cardiac autonomic nervous control. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Research articles: Prevention Source Type: research
Left atrial conduit function modulates right ventricular afterload, exercise capacity and survival in heart failure patients
Aims
To assess if left atrial phasic function characteristics modulate functional capacity/survival by impacting on the pulsatile component of right ventricular (RV) afterload, as represented by pulmonary arterial compliance (PAC).
Materials and methods
Sixty heart failure patients (67 ± 11 years, ejection fraction 39 ± 11%, range 20--62%) underwent 6 min walk test (6MWT) and 3D transthoracic echocardiography. Left atrial conduit was computed off-line, gathering simultaneous real-time 3D multibeats (six cycles) left atrial and left ventricular (LV) volume curves, with conduit (time) = [LV (time...
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Research articles: Prevention Source Type: research
Bridge to heart transplantation in patients with cardiogenic shock: a 20-year experience with two different surgical strategies
Aims
We aimed to describe how treatment of patients in cardiogenic shock bridged to heart transplantation with mechanical circulatory support, using either biventricular assist devices (BVADs) or extracorporeal life support (ECLS), has evolved in the last 20 years in our centre.
Methods
Since 1998, 72 patients with refractory heart failure and indication for heart transplantation have received mechanical circulatory support: 40 had an ECLS system and 32 a BVAD.
Results
Early mortality was similar (17.5 vs. 9.4%, P = 0.25) regardless of the type of support. After a median support time of 8 (1–27) vs....
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Research articles: Heart failure Source Type: research
Imaging predictors of incident heart failure: a systematic review and meta-analysis
Conclusion
LVEF less than 50%, left ventricular dilation and diastolic dysfunction are independent predictors of incident heart failure among asymptomatic individuals, while left ventricular hypertrophy seems less predictive. These findings may serve as a framework for implementing imaging-based screening strategies in patients at risk of heart failure and inform future studies testing preventive or therapeutic approaches aiming at thwarting or halting the progression from asymptomatic (preclinical) to overt heart failure. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 7, 2021 Category: Cardiology Tags: Research articles: Heart failure Source Type: research
