Why fear can be fatal?
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Case reports and images in cardiovascular medicine Source Type: research

Metal through metal: pacing lead across a mechanical tricuspid valve
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Case reports and images in cardiovascular medicine Source Type: research

Use of intermittent high negative pressure vacuum-assisted closure for pediatric poststernotomy mediastinitis
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Case reports and images in cardiovascular medicine Source Type: research

The ‘respect rather than resect’ principle in mitral valve repair: the lateral dislocation of the P2 technique
Conclusion: The lateral dislocation of P2 is an easily fine-tuned technique for isolated P2 prolapse, with the advantage of short aortic cross-clamp and cardiopulmonary bypass times. We think it might be very favorable in older and frail patients. Long-term follow-up is necessary to assess the durability of this technique. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Research articles: Mitral valve disease Source Type: research

Effects of levosimendan in patients with severe functional mitral regurgitation undergoing MitraClip implantation
Conclusion: Prophylactic levosimendan did not affect long-term outcome in patients undergoing PMVR. However, levosimendan as an adjunctive therapy to MitraClip implantation offers further therapeutic advantages in patients with advanced heart failure by improving systolic right ventricle function. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Research articles: Mitral valve disease Source Type: research

Global longitudinal strain predicts outcome after MitraClip implantation for secondary mitral regurgitation
Aim: The aim of this study was to assess preoperative determinants, prevalence, and prognostic impact of left ventricular (LV) reverse remodeling (LVRR) in patients with secondary mitral regurgitation (SMR), undergoing MitraClip implantation (MCi). Methods: From March 2012 to January 2015, a total of 41 consecutive patients with moderate-to-severe SMR treated successfully with MCi were enrolled. All patients underwent clinical and echocardiographic follow-up after MCi. Global longitudinal strain (GLS) was obtained using two dimensional speckle tracking analysis. A reduction in LV end-systolic volume more than 10% compared...
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Research articles: Mitral valve disease Source Type: research

Comparison of vernakalant and ranolazine in atrial fibrillation
Background: Current guidelines recommend vernakalant for pharmacologic cardioversion of recent-onset atrial fibrillation. However, this drug is not established as chronic therapy. Methods and results: In total, 15 rabbit hearts were Langendorff-perfused. A burst pacing protocol-induced atrial fibrillation in 7 of 15 hearts at baseline (10 episodes). Subsequently, a combination of acetylcholine and isoproterenol (ACH/ISO) has been administered to increase occurrence of atrial fibrillation resulting in a reduction of atrial action potential duration (−25 ms, P  (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Research articles: Atrial arrhythmias Source Type: research

Efficacy of second-generation cryoballoon ablation in paroxysmal and persistent atrial fibrillation patients
In this study, we aimed to compare the efficacy of single pulmonary vein isolation with the second-generation cryoballoon (CB-Adv) and predictors of atrial fibrillation recurrences in patients with paroxysmal (PAF) and persistent atrial fibrillation (PersAF). Methods: Consecutive PAF and PersAF patients undergoing CB-Adv for the first time were enrolled. Patients were followed with in-clinic visits including Holter ECG. Atrial arrhythmic episodes symptomatic or documented lasting more than 30 s were considered as recurrences. Results: A total of 96 consecutive patients [77 men (80%), mean age 57.4 ± 9.9 year...
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Research articles: Atrial arrhythmias Source Type: research

Chitinase-3-like protein-1 (YKL-40) before and after therapy in supraventricular arrhythmias
Background: The inflammatory glycoprotein chitinase-3-like protein 1 or YKL-40 has emerged as a potential biomarker of cardiovascular diseases, including atrial fibrillation (AFib). We sought to assess YKL-40 in a wide spectrum of supraventricular arrhythmias besides AFib in comparison with other inflammatory markers. Methods: We determined serum levels of YKL-40, C-reactive protein (CRP) and IL-6 in 70 patients with AFib, atrial flutter, atrioventricular node reentry tachycardia or other supraventricular tachycardias before, immediately after therapy and 1 week after therapy; 20 healthy patients served as controls. Patie...
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Research articles: Atrial arrhythmias Source Type: research

Baroreflex activation therapy: a new approach to the management of advanced heart failure with reduced ejection fraction
Chronic heart failure is a common clinical condition characterized by persistent excessive sympathetic nervous system activation. The derangement of the sympathetic activity has relevant implications for disease progression and patient survival. Aiming to positively impact patient outcome, autonomic nervous system modulatory therapies have been developed and tested in animal and clinical studies. As a general gross assumption, direct vagal stimulation and baroreflex activation are considered equivalent. This assumption does not take into account the fact that direct cervical vagal nerve stimulation involves activation of b...
Source: Journal of Cardiovascular Medicine - August 17, 2017 Category: Cardiology Tags: Review Source Type: research

Stress echo in Italy: state-of-the-art 2015
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research letters Source Type: research

Appropriateness of use criteria in echocardiography: an Italian experience
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research letters Source Type: research

Epicardial collaterals spasm as a cause of ST elevation myocardial infarction
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Atypical recurrence of Takotsubo syndrome: giant T-wave inversion and huge QTc prolongation
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Altered fasting glycemia in cardiac patients during in-hospital rehabilitation: impact on short and long-term follow-up
Background and aims: Hospitalized patients after acute cardiovascular events have poorer prognosis if glucose regulation is diagnosed as abnormal. We compared the short and long-term outcome of patients with newly diagnosed altered fasting glycemia (AFG) to that of known diabetic patients and patients with normal glucose regulation (NGR) after admission to cardiac rehabilitation. Methods: We retrospectively analyzed 2490 consecutive patients. Three groups were identified: known diabetes mellitus (n = 540, 22%), fasting glycemia above 110 mg/dl (AFG, n = 269, 11%), and fasting glycemia 110 mg/dl or less (NGR, n...
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

‘PERFSCORE’ – a multidimensional score: a simple way to predict the success of cardiac rehabilitation
Conclusion: In conclusion, we propose an easy algorithm to calculate the success of cardiac rehabilitation. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Detrimental effects of a bout of physical exercise on circulating endogenous inhibitors of endothelial function in patients with coronary artery disease
Background: A bout of intense physical activity has been shown to transiently impair endothelial function; however, the underlying mechanisms are unclear. Aim: The purpose of the review was to assess the impact of a bout of physical exercise induced by exercise stress echocardiography, on blood concentration of the endogenous inhibitors of nitric oxide synthase, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA), in patients with atherosclerosis. Methods: Overall, 83 study participants were enrolled, 25 coronary artery disease (CAD) patients, 20 age and sex-matched asymptomatic study participants w...
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Acquired coronary artery disease in adult patients with congenital heart disease: a true or a false problem?
Conclusion: Acquired CAD may coexist with congenital heart defects but the association is quite rare. It typically occurs later during adulthood and it is usually associated with atrial septal defect. Acquired CAD and congenital heart defects can be treated contemporarily with good early and late results. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Liberal bilateral internal thoracic artery use in people with diabetes neutralizes the negative impact of insulin-requiring status
Conclusion: In diabetic patients, the insulin-requiring status is by itself a risk factor neither for in-hospital death nor for poor late outcomes after routine BITA grafting. Only the risk of prolonged invasive ventilation and deep sternal wound infection are increased early after surgery. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Evaluation of a protocol for same-day discharge after radial lounge monitoring in a southern Swiss referral percutaneous coronary intervention centre
Aims: The aim of the study was to retrospectively evaluate safety and patient satisfaction of same-day discharge after elective radial coronary angiography/percutaneous coronary intervention (PCI) after the implementation of a radial lounge facility. Methods: All patients admitted to our radial lounge with a planned same-day discharge after an uncomplicated coronary angiography/PCI, having a co-living caregiver, were day enrolled in the study. Rates of same-day discharge, unplanned overnight stay, and in-hospital and first complications [death, myocardial infarction (MI), unplanned coronary angiography, access site hemato...
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Antithrombotic strategies in the catheterization laboratory for patients with acute coronary syndromes undergoing percutaneous coronary interventions: insights from the EmploYEd antithrombotic therapies in patients with acute coronary Syndromes HOspitalized in iTalian cardiac care units Registry
Conclusion: In our contemporary, nationwide, all-comers cohort of ACS patients undergoing PCI, antithrombotic therapies were commonly initiated before the catheterization laboratory. In the periprocedural period, the most frequently employed drugs were unfractioned heparin, leading to a high rate of crossover, followed by GPIs and bivalirudin, mainly used during complex PCI. Clinical Trial Registration. URL: http://www.clinicaltrials.gov . Unique identifier: NCT02015624. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Management of diabetic patients hospitalized for acute coronary syndromes: a prospective multicenter registry
Background: Patients with diabetes mellitus and acute coronary syndrome (ACS) present an increased risk of adverse cardiovascular events. An Italian Consensus Document indicated ‘three specific must’ to obtain in this subgroup of patients: optimal oral antiplatelet therapy, early invasive approach and a tailored strategy of revascularization for unstable angina/non-ST-elevation-myocardial infarction (UA/NSTEMI); furthermore, glycemia at admission should be managed with dedicated protocols. Aim: To investigate if previous recommendations are followed, the present multicenter prospective observational registry w...
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Characteristics, in-hospital management and outcome of late acute ST-elevation myocardial infarction presenters
Background: Patients with delayed presentation of acute myocardial infarction with ST-segment elevation (STEMI) frequently have a poor prognosis but literature about acute complications in intensive cardiac care unit (ICCU) and in-hospital outcome are still limited. Methods: All STEMI patients admitted to our institution between June 2007 and December 2013 were divided into patients presenting more than 12 h after symptom onset (lateSTEMI) and within 12 h (STEMI). Baselines clinical features including details about treatment of choice were collected. Major acute complications in ICCU and in-hospital mortality were the...
Source: Journal of Cardiovascular Medicine - June 30, 2017 Category: Cardiology Tags: Research articles Source Type: research

Awareness of hypertension consequences is less than awareness of risk factors for hypertension
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research letters Source Type: research

The prognostic value of red cell distribution width in ST segment elevation myocardial infarction is independent of necrosis size
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research letters Source Type: research

Trends in length of hospital stay in acute pulmonary embolism over the years. What is changing in the era of direct oral anticoagulants?
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research letters Source Type: research

An individualized left ventricular lead-targeting strategy improves long-term survival of cardiac resynchronization therapy patients and influences the benefit of the implantable cardioverter-defibrillator: a long-term follow-up of the TARGET study
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research letters Source Type: research

Reveal LINQTM experience out of the electrophysiology lab
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research letters Source Type: research

Anticoagulation therapy in elderly patients with atrial fibrillation: results from the Registry of Atrial Fibrillation To Investigate the Implementation of New Guidelines (RAFTING)
Background: Patients with atrial fibrillation aged 75 years or older have a CHA2DS2VASc score that dictates oral anticoagulants. We recorded physicians’ anticoagulation attitudes in elderly patients with atrial fibrillation and assessed the impact of stroke and bleeding risk. Methods: Atrial Fibrillation To Investigate the Implementation of New Guidelines , a countrywide prospective registry performed in Greece during 2010, a period when only vitamin-K antagonists (VKA) were available, enrolled 1127 patients with atrial fibrillation diagnosis during Emergency Departments visit in 31 representative hospitals; 807 pat...
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research articles Source Type: research

Prevalence and predictors of long corrected QT interval in HIV-positive patients: a multicenter study
Conclusion: A low CD4+ cell count is associated with long cQT independently from HAART in HIV-positive patients and may be useful to correctly stratify arrhythmic risk in these patients. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research articles Source Type: research

Ranolazine therapy in drug-refractory ventricular arrhythmias
Conclusion: In this small study, ranolazine proved to be effective, well tolerated, and safe in reducing ventricular arrhythmia episodes and ICD interventions in patients with recurrent antiarrhythmic drug-refractory events. In addition, none of the patients with chronic angina developed major ventricular arrhythmias. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research articles Source Type: research

Anatomic relationship between left coronary artery and left atrium in patients undergoing atrial fibrillation ablation
Conclusion: The anatomic relationship between left atrium and coronary arteries is extremely relevant when performing atrial fibrillation TCA by extensive lesions. Therefore, at least in the latter case, preablation imaging should be recommended to avoid rare, but potentially life-threatening, complications with the aim of an as well tolerated as possible procedure. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research articles Source Type: research

Learning curve using the second-generation cryoballoon ablation
Aims: To study the learning curve with the second-generation cryoballoon technology focusing on safety, efficacy and procedural characteristics. Methods: We included 300 patients (men 64.6%, mean age 58.3 ± 12.4 years), 240 of whom were treated by four operators without prior experience in atrial fibrillation ablation and compared them with 60 consecutive patients treated by senior operator. To study the learning curves, we divided the study period into two trimesters and analyzed procedure duration, fluoroscopy times, complications, characteristics of the freeze–thaw cycles and midterm outcomes. Results...
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research articles Source Type: research

Femoral venous pressure waveform as indicator of phrenic nerve injury in the setting of second-generation cryoballoon ablation
Conclusion: In conclusion, this novel method assessing the VPW for predicting PNI is inexpensive, easily available, with reproducible measurements, and appears to be more effective than traditional assessment methods. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Research articles Source Type: research

Lung ultrasonography: a practical guide for cardiologists
Lung ultrasonography is a well established, user-friendly and easy-to-use technique that can be used in the evaluation of several pathological conditions affecting the lung. Adding lung ultrasonography to traditional echocardiography provides an integrated cardiopulmonary ultrasound analysis. The simultaneous collection of information about the heart and the lungs can help physicians to investigate acute and chronic cardio-pulmonary conditions within a noninvasive, single-probe and all-in-one examination, not exposing the patient to the danger of ionizing radiation. We here briefly review the echographic techniques used to...
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Reviews Source Type: research

Obstructive sleep apnoea–hypopnoea and arrhythmias: new updates
Conclusion: Arrhythmias are frequent in OSAH. Treatment of OSAH may reduce some of them. An implantable cardioverter-defibrillator and continuous positive airway pressure should be considered in some patients. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Reviews Source Type: research

Impact of targeting adenosine-induced transient venous reconnection in patients undergoing pulmonary vein isolation for atrial fibrillation: a meta-analysis of 3524 patients
Conclusion: Additional ablation aiming to eliminate adenosine-induced transient pulmonary vein reconnection failed to reduce the risk of atrial fibrillation recurrence at follow-up. Moreover, although adenosine-guided PVI is not affected by an augmented risk of adverse events, it is associated with a NS increased fluoroscopy exposure and significantly longer procedure duration. Further studies are required to identify the actual role of adenosine in PVI. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Reviews Source Type: research

Dabigatran in nonvalvular atrial fibrillation: from clinical trials to real-life experience
Atrial fibrillation is the most common arrhythmia in over-midlife patients. In addition to systolic heart failure, cerebral thromboembolism represents the most dramatic complication of this rhythm disorder, contributing to morbidity and mortality. Traditionally, anticoagulation has been considered the main strategy in preventing stroke and systemic embolism in atrial fibrillation patients and vitamin K-dependent antagonists have been widely used in clinical practice. Recently, the development of direct oral anticoagulants has certainly improved the management of this disease, providing, for the first time, the opportunity ...
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Reviews Source Type: research

Cooling techniques in mild hypothermia after cardiac arrest
Therapeutic hypothermia has been shown to reduce brain damage due to postcardiac arrest syndrome. Actually, there is no agreement on which is the best device to perform therapeutic hypothermia. The ‘ideal’ device should not only ‘cool’ patient until 33–34°C as fast as possible, but also maintain the target temperature and reverse the therapeutic hypothermia. For out-of-hospital cardiac arrest, there are devices that allow starting of therapeutic hypothermia on the field (prehospital hypothermia). On hospital arrival, these prehospital devices can be quickly and easily replaced with other d...
Source: Journal of Cardiovascular Medicine - May 19, 2017 Category: Cardiology Tags: Reviews Source Type: research

‘Full-metal Jacket’ treatment of multiple paravalvular leaks
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Congenital heart disease: Images in cardiology Source Type: research

Transcatheter treatment of ‘complex’ malfunction of tricuspid valve prosthesis
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Congenital heart disease: Images in cardiology Source Type: research

Real-world use of ticagrelor and prasugrel in patients with NSTEMI undergoing percutaneous coronary intervention
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Congenital heart disease: Research letters Source Type: research

Short-term cardiopulmonary efficiency improvement after transcatheter baffle leak closure in a Mustard-operated patient
No abstract available (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Congenital heart disease: Research letters Source Type: research

Sometimes they come back: recurrent noncardiac right-to-left shunt after percutaneous patent foramen ovale closure
An increasing number of patients are being evaluated for percutaneous patent foramen ovale (PFO) closure to prevent recurrent cerebrovascular events, but debate still exists on therapeutic indications and off-label closure device implantation. Pulmonary arteriovenous fistulas (PAVFs) are a rare and heterogeneous malformation prevalently associated with Rendu–Osler–Weber syndrome, and may mimic PFO right-to-left shunt (RLS), leading to unnecessary interventions and in some cases to relapses. Residual shunt is increasingly being observed both after PFO closure and PAVF embolization, even at long-term follow-up, w...
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Congenital heart disease: Research letters Source Type: research

Off-label use of Amplatzer Duct Occluder II additional sizes
Conclusion: In our case series, ADO II-AS was well tolerated, versatile and cost-effective in treatment of different types of nonduct shunt lesions, mainly in young children and in older patients with comorbidities. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Research articles: Valve disease Source Type: research

Percutaneous management of failed bioprosthetic pulmonary valves in patients with congenital heart defects
Aims: We reviewed our center experience in the field of transcatheter pulmonary valve-in-valve implantation (TPViV), that is emerging as a treatment option for patients with pulmonary bioprosthetic valve (BPV) dysfunction. Methods: Between April 2008 and September 2015, a total of six patients with congenital heart disease (four men) underwent TPViV due to stenosis of preexisting BPV. Four patients received a Melody Medtronic Transcatheter Pulmonary Valve and two an Edward Sapien Valve. Results: No procedural-related complications occurred. After valve implantation, right ventricular systolic pressure (RVSP, 80.5 &plus...
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Research articles: Valve disease Source Type: research

Aortoventricular annulus shape as a predictor of pacemaker implantation following transcatheter aortic valve replacement
Aims: Conduction abnormalities following transcatheter aortic valve replacement (TAVR) are caused by damage of the aortoventricular conduction tissue during positioning of the valve. Therefore, our aim was to assess whether a higher difference between the long and short diameters of the elliptic aortoventricular annulus will possess higher forces on the annulus, and thus will be a predictor of pacemaker need following TAVR. Methods: We retrospectively analyzed 123 patients who had the aortoventricular annulus measured by computed tomography angiography. The difference between maximal (Dmax) and minimal (Dmin) diameters of...
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Research articles: Valve disease Source Type: research

Transcatheter mitral valve replacement with a novel self-expandable prosthesis: single institutional experience procedural outcomes and follow-up
Conclusion: CardiAQ valve placement is safe using a transapical or transseptal approach. Following valve replacement, there was a marked functional improvement in survivors. Transcatheter mitral valve replacement is a promising therapy for mitral regurgitation in a selected patient population. (Source: Journal of Cardiovascular Medicine)
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Research articles: Valve disease Source Type: research

Relationship between ventricular pressure and coronary artery disease in asymptomatic adult heart transplant recipients
Introduction: The association between data of right heart catheterization and cardiac allograft vasculopathy (CAV) in adult heart transplant (HTx) recipients remains to be determined. Methods and results: This is an observational, retrospective study, including all consecutive asymptomatic HTx patients undergoing routine right and left catheterization. The independent predictive power of pulmonary capillary wedge pressure (PCWP) to predict CAV (classified according to working formulation of a standardized nomenclature for CAV-2010) was the primary end point. Seventy-one patients were included, with a mean time from HTx to...
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research

Impact of coronary revascularization on the clinical and scintigraphic outlook of patients with myocardial ischemia
Aims: The impact of coronary revascularization on outcomes and ischemic burden among patients with objective proof of ischemia is not yet established. We appraised the impact of revascularization on outcomes and residual ischemia in patients with objective evidence of ischemia at myocardial perfusion scintigraphy (MPS). Methods: We queried our database for stable patients with myocardial ischemia at MPS, excluding those with prior myocardial infarction, systolic dysfunction, or cardiomyopathy. The impact of revascularization (defined as revascularization as first follow-up event) on outcomes and changes in myocardial isch...
Source: Journal of Cardiovascular Medicine - April 28, 2017 Category: Cardiology Tags: Research articles: Coronary artery disease Source Type: research