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Specialty: Cardiology
Condition: Cardiomyopathy

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Total 533 results found since Jan 2013.

Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology
Acute right ventricular (RV) failure is a complex clinical syndrome that results from many causes. Research efforts have disproportionately focused on the failing left ventricle, but recently the need has been recognized to achieve a more comprehensive understanding of RV anatomy, physiology, and pathophysiology, and of management approaches. Right ventricular mechanics and function are altered in the setting of either pressure overload or volume overload. Failure may also result from a primary reduction of myocardial contractility owing to ischaemia, cardiomyopathy, or arrhythmia. Dysfunction leads to impaired RV filling ...
Source: European Journal of Heart Failure - March 15, 2016 Category: Cardiology Authors: Veli‐Pekka Harjola, Alexandre Mebazaa, Jelena Čelutkienė, Dominique Bettex, Hector Bueno, Ovidiu Chioncel, Maria G. Crespo‐Leiro, Volkmar Falk, Gerasimos Filippatos, Simon Gibbs, Adelino Leite‐Moreira, Johan Lassus, Josep Masip, Christian Mueller, Tags: Statement Source Type: research

Comparison of linear versus cubic assessment of left atrial size in the prediction of atrial fibrillation development in hypertrophic cardiomyopathy
Left atrial (LA) enlargement evaluated by echocardiography is a very strong predictor of cardiovascular (CV) outcomes such as atrial fibrillation (AF), stroke, congestive heart failure, and CV death in multiple clinical settings [1,2]. As a consequence, researchers have focused their attention on the best method to assess LA size. Left atrium is a thin-walled cardiac chamber directly exposed to left ventricular (LV) pressure during diastole, which represents its afterload. In particular, in hypertrophic cardiomyopathy (HCM), almost all patients have some degree of LV diastolic dysfunction.
Source: International Journal of Cardiology - March 16, 2016 Category: Cardiology Authors: Alessandra Giamundo, Grazia Canciello, Antonio Rapacciuolo, Francesca Musella, Gianluigi Savarese, Teresa Strisciuglio, Eugenio Stabile, Raffaele Izzo, Bruno Trimarco, Maria Angela Losi Source Type: research

High Incidence of De Novo and Subclinical Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy and Cardiac Rhythm Management Device
ConclusionAF is common in patients with HCM who need a CRM device. More than 50% of these patients develop de novo AF that was predominantly subclinical in our cohort.This article is protected by copyright. All rights reserved
Source: Journal of Cardiovascular Electrophysiology - April 5, 2016 Category: Cardiology Authors: IRIS WILKE, KATRIN WITZEL, JULIA MÜNCH, SIMON PECHA, STEPHAN BLANKENBERG, HERMANN REICHENSPURNER, STEPHAN WILLEMS, MONICA PATTEN, ALI AYDIN Tags: Original ‐ Clinical Source Type: research

Global longitudinal strain is associated with heart failure outcomes in hypertrophic cardiomyopathy
Conclusions In patients with HCM, reduced GLS is an independent factor associated with poor cardiac outcomes, and particularly HF outcomes.
Source: Heart - April 24, 2016 Category: Cardiology Authors: Reant, P., Mirabel, M., Lloyd, G., Peyrou, J., Lopez Ayala, J.-M., Dickie, S., Bulluck, H., Captur, G., Rosmini, S., Guttmann, O., Demetrescu, C., Pantazis, A., Tome-Esteban, M., Moon, J. C., Lafitte, S., McKenna, W. J. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Clinical diagnostic tests Heart failure and cardiomyopathies Source Type: research

Myocardial triglyceride content in patients with left ventricular hypertrophy: comparison between hypertensive heart disease and hypertrophic cardiomyopathy
We examined whether myocardial TG content assessed by 1H-MRS was useful for diagnosis in patients with LVH. To quantify myocardial TG content, we conducted 1H-MRS in 35 subjects with LVH. Left ventricular function was measured by cardiac magnetic resonance imaging. Patients were assigned to a hypertensive heart disease (HHD, n = 10) or hypertrophic cardiomyopathy (HCM, n = 25) group based on the histology and/or late gadolinium enhancement pattern. The myocardial TG content was significantly higher in the HHD group than in the HCM group (2.14 ± 1.29 vs. 1.09 ± 0.72 %, P < 0.001). Myocardial TG content were ...
Source: Heart and Vessels - May 2, 2016 Category: Cardiology Source Type: research

Usefulness of Electrocardiographic Patterns at Presentation to Predict Long-Term Risk of Cardiac Death in Patients wtih Hypertrophic Cardiomyopathy
The Objective of this study is to investigate the prognostic significance of 12-lead electrocardiogram (ECG) patterns in a large multicenter cohort of patients with hypertrophic cardiomyopathy (HC). 1004 consecutive patients with HC and a recorded standard ECG (64% men, mean age 50±16 years) were evaluated at 4 Italian centres. The study end-points were sudden cardiac death (SCD) or surrogates, including appropriate implanted cardiac defibrillator discharge and resuscitated cardiac arrest) and major cardiovascular events (including SCD or surrogates and death due to heart failure, cardioembolic stroke or heart transplantation).
Source: The American Journal of Cardiology - May 14, 2016 Category: Cardiology Authors: Elena Biagini, Chiara Pazzi, Iacopo Olivotto, Beatrice Musumeci, Giuseppe Limongelli, Giuseppe Boriani, Giuseppe Pacileo, Vittoria Mastromarino, Maria Letizia Bacchi Reggiani, Massimiliano Lorenzini, Francesco Lai, Alessandra Berardini, Francesca Mingardi Source Type: research

Silent AF and Hypertrophic Stroke Risk: More Data, More Monitoring
This article is protected by copyright. All rights reserved
Source: Journal of Cardiovascular Electrophysiology - May 15, 2016 Category: Cardiology Authors: Jeffrey R. Winterfield, Jamie Voss Tags: Editorial Comment Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter‐Defibrillators Over Time in Ischemic and Dilated Cardiomyopathy Patients
Conclusions: These changes in clinical practice with a shift to primary prevention and rise in non‐ischemic cardiomyopathy implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real life cohort.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - May 15, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, STICHERLING CHRISTIAN, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: Original Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter Defibrillators over Time in Ischemic and Dilated Cardiomyopathy Patients
ConclusionThese changes in clinical practice with a shift to primary prevention and rise in non‐ICM implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real‐life cohort.
Source: Pacing and Clinical Electrophysiology : PACE - June 6, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, CHRISTIAN STICHERLING, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: ORIGINAL Source Type: research

Chronic plus binge ethanol feeding induces myocardial oxidative stress, mitochondrial and cardiovascular dysfunction, and steatosis
Alcoholic cardiomyopathy in humans develops in response to chronic excessive alcohol consumption; however, good models of alcohol-induced cardiomyopathy in mice are lacking. Herein we describe mouse models of alcoholic cardiomyopathies induced by chronic and binge ethanol (EtOH) feeding and characterize detailed hemodynamic alterations, mitochondrial function, and redox signaling in these models. Mice were fed a liquid diet containing 5% EtOH for 10, 20, and 40 days (d) combined with single or multiple EtOH binges (5 g/kg body wt). Isocalorically pair-fed mice served as controls. Left ventricular (LV) function and morpholo...
Source: AJP: Heart and Circulatory Physiology - June 7, 2016 Category: Cardiology Authors: Matyas, C., Varga, Z. V., Mukhopadhyay, P., Paloczi, J., Lajtos, T., Erdelyi, K., Nemeth, B. T., Nan, M., Hasko, G., Gao, B., Pacher, P. Tags: Call for Papers: Cardiovascular Mitochondria and Redox Control Source Type: research

0137 : Takotsubo cardiomyopathy following acute cerebral events
Conclusion Takotsubo cardiomyopathy can develop early within in the first days after an acute cerebral event, predominantly in women with insular or posterior fossa lesions and induced by possible vegetative reactions. The author hereby declares no conflict of interest
Source: Archives of Cardiovascular Diseases Supplements - June 15, 2016 Category: Cardiology Source Type: research

Resolution of left ventricular thrombus with apixaban in a patient with hypertrophic cardiomyopathy.
Abstract Anticoagulation with warfarin is the main treatment of intracardiac thrombus. While novel oral anticoagulants (NOACs) have been approved by the US Food and Drug Administration (FDA) for stroke prevention in patients with nonvalvular atrial fibrillation (AF), they are not indicated for resolution of intracardiac thrombus. The case of a 60-year-old woman with left ventricular (LV) thrombus secondary to hypertrophic cardiomyopathy and AF is described in the present report. Indications for oral anticoagulation were AF and LV thrombus. Thrombus was dissolved after 1 month of apixaban treatment. To the best of ...
Source: Turk Kardiyoloji Dernegi arsivi - May 31, 2016 Category: Cardiology Authors: Kaya A, Hayıroğlu Mİ, Keskin M, Tekkeşin Aİ, Alper AT Tags: Turk Kardiyol Dern Ars Source Type: research

Prognostic Implications of Left Ventricular Scar Determined by Late Gadolinium Enhanced Cardiac Magnetic Resonance in Patients with Atrial Fibrillation
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease (CAD) and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with CAD, prior myocardial infarction (MI), or hypertrophic or dilated cardiomyopathy were excluded. The endpoints of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death,...
Source: The American Journal of Cardiology - July 17, 2016 Category: Cardiology Authors: Promporn Suksaranjit, Christopher J. McGann, Nazem Akoum, Joseph Biskupiak, Gregory J. Stoddard, Eugene G. Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F. Marrouche, Brent D. Wilson Source Type: research

Usefulness of Electrocardiographic Patterns at Presentation to Predict Long-term Risk of Cardiac Death in Patients With Hypertrophic Cardiomyopathy
The objective of this study was to investigate the prognostic significance of 12-lead electrocardiogram (ECG) patterns in a large multicenter cohort of patients with hypertrophic cardiomyopathy; 1,004 consecutive patients with hypertrophic cardiomyopathy and a recorded standard ECG (64% men, mean age 50 ± 16 years) were evaluated at 4 Italian centers. The study end points were sudden cardiac death (SCD) or surrogates, including appropriate implanted cardiac defibrillator discharge and resuscitated cardiac arrest and major cardiovascular events (including SCD or surrogates and death due to heart f ailure, cardioembolic st...
Source: The American Journal of Cardiology - May 14, 2016 Category: Cardiology Authors: Elena Biagini, Chiara Pazzi, Iacopo Olivotto, Beatrice Musumeci, Giuseppe Limongelli, Giuseppe Boriani, Giuseppe Pacileo, Vittoria Mastromarino, Maria Letizia Bacchi Reggiani, Massimiliano Lorenzini, Francesco Lai, Alessandra Berardini, Francesca Mingardi Tags: Cardiomyopathy Source Type: research